Zu "K04289" wurden 39 Artikel gefunden!
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UCM-05194 (ammonium salt)
Artikelnummer: Cay41682-1
UCM-05194 is an agonist of lysophosphatidic acid receptor 1 (LPA1). It induces calcium mobilization in RH7777 cells expressing LPA1 (EC50 = 0.24 µM). It is selective for LPA1 over LPA2 and LPA3 at 10 µM and is 10-fold selective over LPA5 and 50-fold selective over LPA4, LPA6, and autotaxin. UCM-05194 (1 µM) induces...
| Schlagworte: | benzenedecanoic acid, (1S)-1-(bromomethyl)-2-(phosphonooxy)ethyl ester, monoammonium salt |
| Anwendung: | Lysophosphatidic acid receptor 1 (LPAR1, EDG2, LPA1) agonist |
| MW: | 482.4 D |
ab 130,00 €
PE(18:1(9Z)/0:0)
Artikelnummer: TGM-T37280-10mg
Description: PE(18:1(9Z)/0:0) is a naturally-occurring lysophospholipid and an analog of plasmalogen lysophosphatidylethanolamine. PE(18:1(9Z)/0:0) induces transient increases in intracellular calcium in PC12 rat neuronal cells in a concentration-dependent manner. PE(18:1(9Z)/0:0) increases the production of IL-4...
| Anwendung: | Lysophospholipid |
| CAS | 89576-29-4 |
| MW: | 479.59 D |
ab 39,00 €
1-Stearoyl-2-docosahexaenoyl-sn-glycero-3-PC
Artikelnummer: TGM-T38218-10mg
Description: 1-Stearoyl-2-docosahexaenoyl-sn-glycero-3-PC is a phospholipid in biological membranes containing stearic acid and docosahexaenoic acid at the sn-1 and sn-2 positions, respectively. It has been used to study the organization and dynamics of lipid membranes. In the superoxide dismutase 1 mutant...
| Anwendung: | Lysophospholipid |
| CAS | 59403-52-0 |
| MW: | 834.16 D |
ab 187,00 €
BMS-986020
Artikelnummer: TGM-T4016-100mg
Description: BMS-986020 (AM152) is a selective LPA1 antagonist. Target: LPA Receptor, LPL Receptor. Smiles: C[C@@H](OC(=O)Nc1c(C)noc1-c1ccc(cc1)-c1ccc(cc1)C1(CC1)C(O)=O)c1ccccc1. References: Kihara Y et al. Lysophospholipid receptors in drug discovery. Exp Cell Res. 2015 May 1,333(2):171-7.
| Schlagworte: | BMS986020, AM152 |
| Anwendung: | LPAR1 antagonist |
| CAS | 1257213-50-5 |
| MW: | 482.53 D |
ab 49,00 €
AM966
Artikelnummer: TGM-T4278-100mg
Description: AM966, a excellent affinity, specific, oral LPA1(IC50=17 nM) antagonist, suppresses LPA-stimulated intracellular calcium release. Target: LPA Receptor, LPL Receptor. Smiles: C[C@@H](OC(=O)Nc1c(C)noc1-c1ccc(cc1)-c1ccc(CC(O)=O)cc1)c1ccccc1Cl. References: Swaney, JS, et al. A novel, orally active LPA1...
| Anwendung: | LPAR1 antagonist |
| CAS | 1228690-19-4 |
| MW: | 490.93 D |
ab 36,00 €
Edg-2 receptor inhibitor 1
Artikelnummer: TGM-T4521-100mg
Description: Edg-2 receptor inhibitor 1 (SAR-100842) is an Edg-2 receptor inhibitor extracted (IC50: <0.1 µM). Target: LPA Receptor. Smiles: N(C(=O)C1=CC(OCCC2=CC(C)=CC=C2)=C(OC)C=C1)C3(C(O)=O)CC=4C(C3)=CC=CC4. References: SCHAEFER, Matthias, et al. ACYLAMINO-SUBSTITUTED FUSED CYCLOPENTA NECARBOXYL ICACIDDERI...
| Schlagworte: | SAR-100842 |
| Anwendung: | Edg-2 receptor (lysophosphatidic acid receptor 1, LPAR1) inhibitor |
| CAS | 1195941-38-8 |
| MW: | 445.51 D |
ab 98,00 €
Ki16425
Artikelnummer: TGM-T6108-100mg
Description: Ki16425 (Debio 0719) is a competitive, potent, and reversible antagonist to LPA1, LPA2, and LPA3, with Ki values of 0.34 µM, 6.5 µM, and 0.93 µM, respectively. Target: LPA Receptor, LPL Receptor. Smiles: CC(OC(=O)Nc1c(C)noc1-c1ccc(CSCCC(O)=O)cc1)c1ccccc1Cl. References: Ohta H, et al, Mol Pharmacol,...
| Schlagworte: | Debio 0719 |
| Anwendung: | LPA receptor antagonist |
| CAS | 355025-24-0 |
| MW: | 474.96 D |
ab 37,00 €
ONO-7300243
Artikelnummer: TGM-T7393-100mg
Description: ONO-7300243 is an antagonist of lysophosphatidic acid receptor 1 (LPA1, IC50 : 0.16 µM). Target: LPA Receptor, LPL Receptor. Smiles: COc1cc(cc(OC)c1C)C(=O)N(CCCc1ccccc1)Cc1ccc(CC(O)=O)cc1. References: Terakado M , Suzuki H , Hashimura K , et al. Discovery of ONO-7300243 from a novel class of...
| Anwendung: | LPA1 antagonist |
| CAS | 638132-34-0 |
| MW: | 461.55 D |
ab 40,00 €
NAEPA
Artikelnummer: TGM-T25847-100mg
Description: NAEPA, an LPA mimetic, is a selective agonist of the lysophosphatidic acid-1 (LPA1) receptor. Target: Others. Smiles: C(C(NCCOP(=O)(O)O)=O)CCCCCC/C=C\CCCCCCCC. References: Woclawek-Potocka I, Kondraciuk K, Skarzynski DJ. Lysophosphatidic acid stimulates prostaglandin E2 production in cultured stromal...
| Anwendung: | Selective LPA1 receptor agonist |
| CAS | 24435-25-4 |
| MW: | 405.51 D |
ab 1.521,00 €
Anti-LPAR1
Artikelnummer: CSB-PA007901.50
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
| Schlagworte: | Anti-EDG2, Anti-LPAR1, Anti-LPA-1, Anti-LPA receptor 1, Anti-Lysophosphatidic acid receptor 1, Anti-Lysophosphatidic acid... |
| Anwendung: | ELISA, WB, IHC, IF |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, rat |
125,00 €
Anti-LPAR1 Recombinant Monoclonal, clone 4C3
Artikelnummer: CSB-RA922556A0HU.100
Isotype: Rabbit IgG. Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Affinity-chromatography. Target Name: LPAR1. Antigen Species: Human
| Schlagworte: | Anti-EDG2, Anti-LPAR1, Anti-LPA-1, Anti-LPA receptor 1, Anti-Lysophosphatidic acid receptor 1, Anti-Lysophosphatidic acid... |
| Anwendung: | ELISA, WB, |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 201,00 €
Anti-LPAR1
Artikelnummer: CSB-PA559394.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: LPAR1. Antigen Species: Human
| Schlagworte: | Anti-EDG2, Anti-LPAR1, Anti-LPA-1, Anti-LPA receptor 1, Anti-Lysophosphatidic acid receptor 1, Anti-Lysophosphatidic acid... |
| Anwendung: | ELISA, WB, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 165,00 €