Zu "K04279" wurden 41 Artikel gefunden!
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Israpafant
Artikelnummer: TGM-T27638-100mg
Description: Israpafant is a selective antagonist for the platelet-activating factor receptor ( IC50 = 0.84nM). Israpafant inhibits PAF-induced human platelet aggregation. Israpafant inhibits the activation of eosinophil cells and consequently delays the development of immune responses. Israpafant also has...
| Schlagworte: | Y-24180, Y24180, Y 24180 |
| Anwendung: | Targets platelet-activating factor receptor (PTAFR) |
| CAS | 117279-73-9 |
| MW: | 489.07 D |
ab 2.421,00 €
Lexipafant
Artikelnummer: TGM-T27821-100mg
Description: Lexipafant is a platelet-activating factor (PAF) receptor antagonist which inhibits the binding of PAF to its receptor, thereby reducing inflammation and associated tissue injury. [Reduce organ damage, mitigate sepsis]. Target: Others. Smiles:...
| Schlagworte: | DO6, BB882, BB-882, GR-167089, DO-6, ISV-611 |
| Anwendung: | Targets platelet-activating factor receptor (PTAFR) |
| CAS | 139133-26-9 |
| MW: | 458.57 D |
ab 1.671,00 €
CV-6209
Artikelnummer: TGM-T27102-10mg
Description: CV-6209 is a potent antagonist of the platelet-activating factor (PAF) receptor. Target: AChE, PAFR. Smiles: [Cl-].O=C(OCC(OC)COC(=O)N(C(=O)C)CC=1C=CC=C[N+]1CC)NCCCCCCCCC CCCCCCCCC. References: Iwao Y, et al. Anti-Helicobacter pylori actions of CV-6209, a platelet-activating factor receptor antagonist....
| Schlagworte: | CV 6209, CV6209 |
| Anwendung: | PTAFR antagonist |
| CAS | 100488-87-7 |
| MW: | 642.31 D |
ab 128,00 €
Ginkgolide C
Artikelnummer: TGM-T2750-1mL
Description: Ginkgolide C (BN-52022), a natural product, can enhance the cardiac function of rats in the body. Target: Endogenous Metabolite, AMPK, Sirtuin, MMP. Smiles: C[C@@H]1C(=O)O[C@H]2[C@@H](O)[C@]34[C@@H]5OC(=O)[C@]3(O[C@@H]3OC(=O)[C@H](O)[C@]43[C@@H]([C@H]5O)C(C)(C)C)[C@@]12O. References: Liou CJ, et al....
| Schlagworte: | BN-52022 |
| Anwendung: | PAF receptor antagonist |
| CAS | 15291-76-6 |
| MW: | 440.4 D |
49,00 €
Ginkgolide B
Artikelnummer: TGM-T2751-1mL
Description: Ginkgolide B (BN-52021) is a PAFR antagonist(IC50=3.6 µM) isolated from Ginkgo biloba. Target: Apoptosis, Endogenous Metabolite, PAFR. Smiles: CC1C(=O)OC2C(O)C34C5CC(C(C)(C)C)C33C(O)C(=O)OC3OC4(C(=O)O5)C12O. References: Lamant V, et al. BiochemPharmacol, 1987, 36(17), 2749-2752.
| Schlagworte: | BN-52021 |
| Anwendung: | PAFr antagonist |
| CAS | 15291-77-7 |
| MW: | 424.4 D |
ab 57,00 €
PAF C-18:1
Artikelnummer: TGM-T36764-10mg
Description: PAF C-18:1 is a naturally occurring phospholipid produced by cells upon stimulation and plays a role in the establishment and maintenance of the inflammatory response. It is less potent than PAF C-16 and PAF C-18 in the induction of neutrophil chemotaxis, but is equipotent to PAF C-16 and PAF C-18 in...
| Anwendung: | Phospholipid, eosinophil migration promotor |
| CAS | 85966-90-1 |
| MW: | 549.73 D |
ab 198,00 €
LAU-0901
Artikelnummer: TGM-T83777-50mg
Description: LAU-0901, a platelet-activating factor (PAF) receptor antagonist, demonstrates efficacy in reducing infarct volume and enhancing neurological function in rats subjected to middle cerebral artery occlusion (MCAO)-induced cerebral ischemia, at doses of 30, 60, and 90 mg/kg. Furthermore, it diminishes...
| Anwendung: | PAF receptor antagonist |
| CAS | 727358-25-0 |
| MW: | 612.54 D |
Bitte fragen Sie den aktuellen Preis für diesen Artikel an.
Anti-PTAFR
Artikelnummer: CSB-PA109839.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: PTAFR. Antigen Species: Human
| Schlagworte: | Anti-PAFR, Anti-PAFr, Anti-PTAFR, Anti-PAF-R, Anti-Platelet-activating factor receptor, OTTHUMP00000004041 antibody,... |
| Anwendung: | ELISA, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 167,00 €
PAF C-18:1
Artikelnummer: Cay18779-5
PAF C-18:1 is a naturally occurring phospholipid produced by cells upon stimulation and plays a role in the establishment and maintenance of the inflammatory response. It is less potent than PAF C-16 (Cay-60900) and PAF C-18 (Cay-60910) in the induction of neutrophil chemotaxis, but is equipotent to PAF C-16 and PAF...
| Schlagworte: | 1-Oleoyl-2-acetyl-sn-glycero-3-phosphorylcholine, Platelet-activating Factor C-18:1,... |
| Anwendung: | Phospholipid, eosinophil migration promotor |
| CAS | 85966-90-1 |
| MW: | 549.7 D |
ab 111,00 €
CV-6209 (chloride)
Artikelnummer: Cay15955-1
CV-6209 is a potent antagonist of the platelet-activating factor (PAF) receptor, inhibiting aggregation of rabbit and human platelets induced by PAF with IC50 values of 75 and 170 nM, respectively. It has little action on platelet aggregation induced by arachidonic acid, ADP, or collagen. CV-6209 is bioavailable, as...
| Schlagworte: | 2-(2-acetyl-6-methoxy-3,9-dioxo-4,8-dioxa-2,10-diazaoctacos-1-yl)-1-ethyl-pyridinium, monochloride |
| Anwendung: | PTAFR antagonist |
| CAS | 100488-87-7 |
| MW: | 642.3 D |
ab 133,00 €
Anti-PAF Receptor (human) (11A4, Clone 21)
Artikelnummer: Cay160600-1
PAF is a potent phospholipid mediator which exerts diverse biological actions by interaction with a G protein-coupled PAF receptor. The PAF receptor has been cloned from a number of species including human, rat, and guinea pig and is characterized as a 7-transmembrane receptor which induces phosphoinositol turnover...
| Schlagworte: | Anti-PAFR, Anti-PAFr, Anti-PAFr, Anti-PTAFR, Anti-PAF-R, Anti-PAF-R, Anti-Platelet-activating factor receptor,... |
| Anwendung: | ELISA, FC, ICC |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
431,00 €
Apafant
Artikelnummer: Cay14532-1
Platelet-activating factor (PAF) is a biologically active phospholipid that activates platelets, polymorphonuclear leukocytes, monocytes, and macrophages. PAF also increases vascular permeability, decreases cardiac output, induces hypotension, stimulates uterine contraction, and has been implicated in pathological...
| Schlagworte: | WEB 2086,... |
| Anwendung: | PAF receptor antagonist |
| CAS | 105219-56-5 |
| MW: | 456 D |
ab 69,00 €