Zu "K04278" wurden 102 Artikel gefunden!

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JWH 133
JWH 133

Artikelnummer: Cay10005428-1

JWH 133 is a synthetic cannabinoid (CB) that is over 200-fold selective for the peripheral CB2 receptor (Ki = 3.4 nM) over the central CB1 receptor (Ki = 677 nM). It inhibits the growth of tumors in mice, increasing apoptosis and impairing angiogenesis. JWH 133 also suppresses inflammation in experimental colitis...
Schlagworte: 3-(1,1-dimethylbutyl)-6aR,7,10,10aR-tetrahydro-6,6,9-trimethyl-6H-dibenzo[b,d]pyran
Anwendung: Analytical reference standard, peripheral CB2 receptor selective
CAS 259869-55-1
MW: 312.5 D
ab 61,00 €
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Cannabidiol
Cannabidiol

Artikelnummer: Cay90080-5

Cannabidiol (Cay-90080) is an analytical reference material categorized as a phytocannabinoid. Unlike Delta9-THC (Cay-ISO60157, Cay-12068), cannabidiol is non-psychoactive. This product is intended for research and forensic applications.Formal Name:...
Schlagworte: CBD, 2-[1R-3-methyl-6R-(1-methylethenyl)-2-cyclohexen-1-yl]-5-pentyl-1,3-benzenediol
Anwendung: Analytical reference material, non-psychoactive phytocannabinoid
CAS 13956-29-1
MW: 314.5 D
ab 85,00 €
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Magnolol
Magnolol

Artikelnummer: TGM-T3000-100mg

Description: Magnolol (5,5'-Diallyl-2,2'-biphenyldiol) is a dual agonist of RXRalpha( EC50=10.4 µM) and PPARgamma(EC50=17.7 µM). It blocks TNF-alpha-induced NF-KB activation. Target: NF-kappaB, PPAR, p53, Autophagy, Antibacterial, Retinoid Receptor. Smiles: OC=1C(=CC(CC=C)=CC1)C2=CC(CC=C)=CC=C2O. References: Ai...
Schlagworte: NSC 293099, 5,5'-Diallyl-2,2'-biphenyldiol
Anwendung: Metabolic studies, CB2 receptor agonist
CAS 528-43-8
MW: 266.33 D
ab 31,00 €
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Vicasinabin
Vicasinabin

Artikelnummer: TGM-T38912-5mg

Description: Vicasinabin, a potent agonist of cannabinoid receptor 2 (CB2), exhibits promising potential for researching chronic pain, atherosclerosis, regulation of bone mass, neuroinflammation, and related human diseases. Target: Others. Smiles: Cn1nnnc1Cn1nnc2c(nc(nc12)C(C)(C)C)N1CC[C@H](O)C1. References:...
Anwendung: Targets cannabinoid receptor 2 (CNR2)
CAS 1433361-02-4
MW: 358.41 D
787,00 €
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GW 405833
GW 405833

Artikelnummer: TGM-T7705-100mg

Description: GW 405833 (L-768242) is an agonist of cannabinoid-2 (CB(2)) receptor-selective. Target: Cannabinoid Receptor. Smiles: COc1ccc2n(C(=O)c3cccc(Cl)c3Cl)c(C)c(CCN3CCOCC3)c2c1. References: Li A L , Carey L M , Mackie K , et al. The cannabinoid CB 2 agonist GW405833 suppresses inflammatory and neuropathic pain...
Schlagworte: L-768242
Anwendung: Partial CB2 receptor agonist
CAS 180002-83-9
MW: 447.35 D
ab 31,00 €
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LY2828360
LY2828360

Artikelnummer: TGM-T7316-100mg

Description: LY2828360 is a cannabinoid (CB) receptor 2 agonist (Ki = 40.3 nM). It selectively activates CB2 over CB1 in a GTPgammaS binding assay (EC50s = 20.1 and >100,000 nM, respectively). Target: Cannabinoid Receptor. Smiles: CN1CCN(CC1)c1nc(C)nc2n(C3CCOCC3)c(nc12)-c1ccccc1Cl. References: Lin X , Dhopeshwarkar...
Anwendung: CB2 agonist
CAS 1231220-79-3
MW: 426.94 D
ab 38,00 €
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beta-Caryophyllene
beta-Caryophyllene

Artikelnummer: TGM-T9114-500mg

Description: beta-Caryophyllene ((-)-(E)-Caryophyllene) acts as an CB2 receptor agonist. Target: Endogenous Metabolite, Cannabinoid Receptor. Smiles: [H][C@]12CC(C)(C)[C@]1([H])CC\C(C)=C/CCC2=C. References: Cheng Y, etal. beta-Caryophyllene ameliorates the Alzheimer-like phenotype in APP/PS1 Mice through CB2...
Schlagworte: (-)-beta-caryophyllene, (-)-trans-Caryophyllene, (-)-(E)-Caryophyllene
Anwendung: Antioxidant, antineuroinflammatory, antiproliferative, antinociceptive agent
CAS 87-44-5
MW: 204.35 D
42,00 €
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PF-03550096
PF-03550096

Artikelnummer: TGM-T84412-10mg

Description: PF-03550096, an orally active synthetic cannabinoid (CB), selectively binds to peripheral CB2 receptors with a Ki value of 7.9 nM, demonstrating analgesic activity [1]. Target: Others. Smiles: C(N[C@@H]([C@](C)(C)C)C(N)=O)(=O)N1C=2C(N(CCC(C)(C)O)C1=O)=CC=CC2
Anwendung: Synthetic cannabinoid (CB2 receptor)
CAS 910376-39-5
MW: 376.45 D
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SDB-006
SDB-006

Artikelnummer: TGM-T84447-10mg

Description: SDB-006, a cannabimimetic indole, exhibits affinity for central cannabinoid (CB1) and peripheral cannabinoid (CB2) receptors, with EC50 values of 19 nM and 134 nM, respectively. This compound emerged from investigations into JWH 018 adamantyl carboxamide, a related substance known for its illicit sale...
Anwendung: Analytical standard, cannabimimetic indole
CAS 695213-59-3
MW: 320.436 D
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URB447
URB447

Artikelnummer: TGM-T84488-10mg

Description: URB447, a peripherally restricted CB1 cannabinoid antagonist with IC50 values of 313 nM for rat CB1 receptor and 41 nM for human CB2 receptor, effectively reduces food intake and body weight gain in mice. It achieves these effects without penetrating the brain or antagonizing central CB1-dependent...
Anwendung: CB1 receptor antagonist, CB2 receptor agonist
CAS 1132922-57-6
MW: 400.9 D
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CB2/CNR2 Protein, Human, Recombinant
CB2/CNR2 Protein, Human, Recombinant

Artikelnummer: TGM-TMPY-06623-100ug

Description: Genetic variants within the CNR2 gene encoding the cannabinoid receptor CB2 are associated with osteoporosis and low bone mineral density (BMD) in case-control studies. There is a possibility that genetic variants of the CNR1 gene may produce a liability to the complication of psychotic state after...
Schlagworte: CB2, CB-2, CX5
MW: 39.68 kD
ab 839,00 €
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JTE-907
JTE-907

Artikelnummer: TGM-T19705-100mg

Description: JTE-907 is a CB2 receptor inverse agonist with high selectivity and oral activity.JTE-907 exhibits anti-inflammatory activity in vivo. Target: Cannabinoid Receptor. Smiles: CCCCCOc1c(OC)ccc2cc(C(=O)NCc3ccc4OCOc4c3)c(=O)[nH]c12. References: Altun A, et al. Attenuation of morphine antinociceptive...
Schlagworte: JTE 907
Anwendung: Selective CB2 receptor antagonist / inverse agonist
CAS 282089-49-0
MW: 438.47 D
ab 52,00 €
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