Zu "K04278" wurden 107 Artikel gefunden!
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JWH 133
Artikelnummer: Cay10005428-1
JWH 133 is a synthetic cannabinoid (CB) that is over 200-fold selective for the peripheral CB2 receptor (Ki = 3.4 nM) over the central CB1 receptor (Ki = 677 nM). It inhibits the growth of tumors in mice, increasing apoptosis and impairing angiogenesis. JWH 133 also suppresses inflammation in experimental colitis...
| Schlagworte: | 3-(1,1-dimethylbutyl)-6aR,7,10,10aR-tetrahydro-6,6,9-trimethyl-6H-dibenzo[b,d]pyran |
| Anwendung: | Analytical reference standard, peripheral CB2 receptor selective |
| CAS | 259869-55-1 |
| MW: | 312.5 D |
ab 60,00 €
GW 405833
Artikelnummer: TGM-T7705-100mg
Description: GW 405833 (L-768242) is an agonist of cannabinoid-2 (CB(2)) receptor-selective. Target: Cannabinoid Receptor. Smiles: COc1ccc2n(C(=O)c3cccc(Cl)c3Cl)c(C)c(CCN3CCOCC3)c2c1. References: Li A L , Carey L M , Mackie K , et al. The cannabinoid CB 2 agonist GW405833 suppresses inflammatory and neuropathic pain...
| Schlagworte: | L-768242 |
| Anwendung: | Partial CB2 receptor agonist |
| CAS | 180002-83-9 |
| MW: | 447.35 D |
ab 34,00 €
A-836339
Artikelnummer: TGM-T7375-100mg
Description: A-836339 acts as a potent cannabinoid receptor full agonist which has a higher affinity for the peripheral CB2 receptor (Ki = 0.64 nM) over the central CB1 receptor (Ki = 270 nM). It displays analgesic, anti-inflammatory, and anti-hyperalgesic effects in mice. Target: Cannabinoid Receptor. Smiles:...
| Anwendung: | Synthetic cannabinoid, analgesic, antiinflammatory, antihyperalgesic |
| CAS | 959746-77-1 |
| MW: | 310.45 D |
ab 39,00 €
LY2828360
Artikelnummer: TGM-T7316-100mg
Description: LY2828360 is a cannabinoid (CB) receptor 2 agonist (Ki = 40.3 nM). It selectively activates CB2 over CB1 in a GTPgammaS binding assay (EC50s = 20.1 and >100,000 nM, respectively). Target: Cannabinoid Receptor. Smiles: CN1CCN(CC1)c1nc(C)nc2n(C3CCOCC3)c(nc12)-c1ccccc1Cl. References: Lin X , Dhopeshwarkar...
| Anwendung: | CB2 agonist |
| CAS | 1231220-79-3 |
| MW: | 426.94 D |
ab 37,00 €
beta-Caryophyllene
Artikelnummer: TGM-T9114-500mg
Description: beta-Caryophyllene ((-)-(E)-Caryophyllene) acts as an CB2 receptor agonist. Target: Endogenous Metabolite, Cannabinoid Receptor. Smiles: [H][C@]12CC(C)(C)[C@]1([H])CC\C(C)=C/CCC2=C. References: Cheng Y, etal. beta-Caryophyllene ameliorates the Alzheimer-like phenotype in APP/PS1 Mice through CB2...
| Schlagworte: | (-)-beta-caryophyllene, (-)-trans-Caryophyllene, (-)-(E)-Caryophyllene |
| Anwendung: | Antioxidant, antineuroinflammatory, antiproliferative, antinociceptive agent |
| CAS | 87-44-5 |
| MW: | 204.35 D |
41,00 €
PF-03550096
Artikelnummer: TGM-T84412-10mg
Description: PF-03550096, an orally active synthetic cannabinoid (CB), selectively binds to peripheral CB2 receptors with a Ki value of 7.9 nM, demonstrating analgesic activity [1]. Target: Others. Smiles: C(N[C@@H]([C@](C)(C)C)C(N)=O)(=O)N1C=2C(N(CCC(C)(C)O)C1=O)=CC=CC2
| Anwendung: | Synthetic cannabinoid (CB2 receptor) |
| CAS | 910376-39-5 |
| MW: | 376.45 D |
Bitte fragen Sie den aktuellen Preis für diesen Artikel an.
SDB-006
Artikelnummer: TGM-T84447-10mg
Description: SDB-006, a cannabimimetic indole, exhibits affinity for central cannabinoid (CB1) and peripheral cannabinoid (CB2) receptors, with EC50 values of 19 nM and 134 nM, respectively. This compound emerged from investigations into JWH 018 adamantyl carboxamide, a related substance known for its illicit sale...
| Anwendung: | Analytical standard, cannabimimetic indole |
| CAS | 695213-59-3 |
| MW: | 320.436 D |
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URB447
Artikelnummer: TGM-T84488-10mg
Description: URB447, a peripherally restricted CB1 cannabinoid antagonist with IC50 values of 313 nM for rat CB1 receptor and 41 nM for human CB2 receptor, effectively reduces food intake and body weight gain in mice. It achieves these effects without penetrating the brain or antagonizing central CB1-dependent...
| Anwendung: | CB1 receptor antagonist, CB2 receptor agonist |
| CAS | 1132922-57-6 |
| MW: | 400.9 D |
Bitte fragen Sie den aktuellen Preis für diesen Artikel an.
CB2/CNR2 Protein, Human, Recombinant
Artikelnummer: TGM-TMPY-06623-100ug
Description: Genetic variants within the CNR2 gene encoding the cannabinoid receptor CB2 are associated with osteoporosis and low bone mineral density (BMD) in case-control studies. There is a possibility that genetic variants of the CNR1 gene may produce a liability to the complication of psychotic state after...
| Schlagworte: | CB2, CB-2, CX5 |
| MW: | 39.68 kD |
ab 821,00 €
JTE-907
Artikelnummer: TGM-T19705-100mg
Description: JTE-907 is a CB2 receptor inverse agonist with high selectivity and oral activity.JTE-907 exhibits anti-inflammatory activity in vivo. Target: Cannabinoid Receptor. Smiles: CCCCCOc1c(OC)ccc2cc(C(=O)NCc3ccc4OCOc4c3)c(=O)[nH]c12. References: Altun A, et al. Attenuation of morphine antinociceptive...
| Schlagworte: | JTE 907 |
| Anwendung: | Selective CB2 receptor antagonist / inverse agonist |
| CAS | 282089-49-0 |
| MW: | 438.47 D |
ab 51,00 €
GW842166X
Artikelnummer: TGM-T6527-100mg
Description: GW842166X is a potent and highly selective agonist of cannabinoid receptor CB2 receptor with EC50 of 63 nM, shows no significant activity at CB1 receptor. Phase 2. Target: Cannabinoid Receptor. Smiles: FC(F)(F)c1nc(Nc2cc(Cl)cc(Cl)c2)ncc1C(=O)NCC1CCOCC1. References: Giblin GM, et al. J Med Chem, 2007,...
| Anwendung: | CB2 receptor agonist |
| CAS | 666260-75-9 |
| MW: | 449.25 D |
ab 31,00 €
BML-190
Artikelnummer: TGM-T6417-100mg
Description: BML-190 (Indomethacin morpholinylamide) is a specific CB2 receptor inverse agonist (Ki: 435 nM), with 50-fold selectivity over CB1 receptor. Target: Cannabinoid Receptor. Smiles: COc1ccc2n(C(=O)c3ccc(Cl)cc3)c(C)c(CC(=O)N3CCOCC3)c2c1. References: New DC, et al. FEBS Lett. 2003, 536(1-3), 157-160.
| Schlagworte: | Indomethacin morpholinylamide, IMMA, BML 190 |
| Anwendung: | CB2 receptor agonist |
| CAS | 2854-32-2 |
| MW: | 426.89 D |
ab 39,00 €