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Iloprost
Iloprost

Artikelnummer: LKT-I458579.1

Iloprost is a synthetic analogue of prostacyclin. This product includes a mixture of 4R and 4S diastereomers. SMILES: CC#CCC(C)C(C=CC1C(CC2C1CC(=CCCCC(=O)O)C2)O)O
Schlagworte: Cilaprost, Ventavis, Endoprost, Ilomedin, Iloprostum, UNII-JED5K35YGL, ZK-36374, JED5K35YGL,...
Anwendung: Prostacyclin analog
CAS 78919-13-8
MW: 360.5 D
ab 313,00 €
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Treprostinil diethanolamine
Treprostinil diethanolamine

Artikelnummer: TGM-T63349-100mg

Description: Treprostinil diethanolamine (UT-15C) is a potent agonist of EP2, DP1, and IP, with values of 3.6, 4.4, and 32.1 nM for EP2, DP1, and IP, respectively, and 212, 826, 2505, and 4680 nM for EP1, EP4, EP3, and FPKi, respectively. Treprostinil diethanolamine contributes to the upregulation of cAMP,...
Schlagworte: UT-15C
Anwendung: Targets prostacyclin receptor (PTGIR)
CAS 830354-48-8
MW: 495.65 D
ab 67,00 €
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Epoprostenol sodium
Epoprostenol sodium

Artikelnummer: TGM-T15238-10mg

Description: Epoprostenol sodium is a potent inhibitor of platelet aggregation used in pulmonary hypertension and transplantation. Target: Others. Smiles: [Na+].CCCCCC(O)C=CC1C(O)CC2OC(CC12)=CCCCC([O-])=O. References: Provencher S, et al.Quality of life, safety and efficacy profile of thermostable flolan in...
Schlagworte: Prostacyclin sodium salt, Prostaglandin I2 sodium salt, Flolan
Anwendung: Targets prostacyclin receptor (PTGIR)
CAS 61849-14-7
MW: 375.461 D
ab 181,00 €
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Iloprost
Iloprost

Artikelnummer: TGM-T15560-1mg

Description: Iloprost is a synthetic analogue of prostacyclin PGI2. Iloprost commonly employed in the treatment of peripheral vascular disease and also indicated in the treatment of patients affected by systemic sclerosis (SSc) in the presence of severe Raynaud's phenomenon (RP). Target: Others. Smiles:...
Schlagworte: Ciloprost, ZK 36374
Anwendung: Targets prostacyclin receptor (PTGIR)
CAS 78919-13-8
MW: 360.49 D
ab 170,00 €
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Epoprostenol
Epoprostenol

Artikelnummer: TGM-T20778-25mg

Description: Epoprostenol, a prostaglandin, is a powerful vasodilator. It inhibits platelet aggregation. Target: Others. Smiles: C(=C/[C@H](CCCCC)O)\[C@@H]1[C@@]2([C@@](O/C(=C\CCCC(O)=O)/C2)(C[C@H]1O)[H])[H]. References: Ahmad KA, Banales J, Henderson CL, Ramos SE, Brandt KM, Powers GC. Intravenous epoprostenol...
Schlagworte: U 53217, U-53,217, U 53,217
Anwendung: Targets prostacyclin receptor (PTGIR)
CAS 35121-78-9
MW: 352.47 D
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Selexipag
Selexipag

Artikelnummer: TGM-T3216-10mg

Description: Selexipag (ACT-293987)(NS-304) is prostacyclin receptor agonist that causes vasodilation in pulmonary vasculature and is used in the therapy of pulmonary arterial hypertension (PAH). Target: Others, Prostaglandin Receptor. Smiles: N(CCCCOCC(NS(C)(=O)=O)=O)(C(C)C)C=1N=C(C(=NC1)C2=CC=CC=C2)C3=CC=CC=C3....
Schlagworte: Uptravi, NS-304, ACT-293987
Anwendung: Targets prostacyclin receptor (PTGIR)
CAS 475086-01-2
MW: 496.62 D
ab 42,00 €
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Beraprost
Beraprost

Artikelnummer: TGM-T30426-25mg

Description: Beraprost is a stable prostacyclin analog. Target: Others. Smiles: CC#CCC(C)C(O)C=CC1C(O)CC2Oc3c(cccc3CCCC(O)=O)C12 , w:9.9, . References: Zhang P, Xu L, Guan H, Liu L, Liu J, Huang Z, Cao X, Liao Z, Xiao H, Li Y. Beraprost sodium, a prostacyclin analogue, reduces fructose-induced hepatocellular...
Schlagworte: ML-1229, MDL-201229, MDL 201229, ML 1229
Anwendung: Targets prostacyclin receptor (PTGIR)
CAS 88430-50-6
MW: 398.499 D
1.520,00 €
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Ciprostene (calcium salt)
Ciprostene (calcium salt)

Artikelnummer: TGM-T36732-10mg

Description: Ciprostene is the 9beta-methyl analog of carbaprostacyclin and a stable analog of PGI2. Ciprostene exhibits biological activity similar to PGI2, but is 30-fold less potent. In patas monkeys, ciprostene induces hypotension and causes tachycardia when administered at a dose of 0.16 µg/kg/min. In addition,...
Anwendung: Targets prostacyclin receptor (PTGIR)
CAS 81703-55-1
MW: 771.146 D
ab 380,00 €
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Ralinepag
Ralinepag

Artikelnummer: TGM-T4635-100mg

Description: Ralinepag (APD811) is a potent, orally bioavailable agonist of non-prostanoid prostacyclin (IP) receptor, with EC50s of 8.5 nM, 530 nM and 850 nM for human and rat IP receptor and human DP1 receptor, respectively. Target: Prostaglandin Receptor, Others. Smiles:...
Schlagworte: APD811
Anwendung: Targets prostacyclin receptor (PTGIR)
CAS 1187856-49-0
MW: 431.91 D
ab 55,00 €
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Treprostinil
Treprostinil

Artikelnummer: TGM-T5150-100mg

Description: Treprostinil (Orenitram) is a potent DP1, IP and EP2 agonist (EC50: 0.6/1.9/6.2 nM). Target: Prostaglandin Receptor. Smiles: CCCCC[C@H](O)CC[C@H]1[C@H](O)C[C@@H]2Cc3c(C[C@H]12)cccc3OCC(O)=O. References: Whittle BJ, et al. Binding and activity of the prostacyclin receptor (IP) agonists, treprostinil and...
Schlagworte: Orenitram, LRX-15, Remodulin
Anwendung: Targets prostacyclin receptor (PTGIR)
CAS 81846-19-7
MW: 390.51 D
ab 40,00 €
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Treprostinil Sodium
Treprostinil Sodium

Artikelnummer: TGM-T5171-10mg

Description: Treprostinil Sodium (UT-15) is a potent DP1, IP and EP2 agonist (EC50: 0.6/1.9/6.2 nM). Target: c-RET, Prostaglandin Receptor, VEGFR. Smiles: [Na+].CCCCC[C@H](O)CC[C@H]1[C@H](O)C[C@@H]2Cc3c(C[C@H]12)cccc3OCC([O-])=O. References: Whittle BJ, et al. Binding and activity of the prostacyclin receptor (IP)...
Schlagworte: UT-15
Anwendung: Targets prostacyclin receptor (PTGIR)
CAS 289480-64-4
MW: 412.5 D
ab 46,00 €
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Clinprost
Clinprost

Artikelnummer: TGM-T68433-100mg

Description: Clinprost is a Vasodilator (peripheral), Platelet aggregation inhibitor, and Prostaglandin I2 receptor agonist. Target: Others. Smiles: C(=C/[C@H](CCCCC)O)\[C@@H]1[C@@]2([C@@](C=C(CCCCC(OC)=O)C2)(C[C@H]1O)[H])[H]
Anwendung: Targets prostacyclin receptor (PTGIR)
CAS 88931-51-5
MW: 364.52 D
ab 1.520,00 €
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