Zu "K04261" wurden 44 Artikel gefunden!
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NEU
Prostaglandin E2 receptor EP4 subtype (Ptger4), partial,...
Artikelnummer: CSB-EP018973MO1.1
Organism: Mus musculus (Mouse). Source: E.coli. Expression Region: 361-513aa. Protein Length: Partial. Tag Info: Tag-Free. Target Protein Sequence: RKTVLSKAIE KIKCLFCRIG GSGRDSSAQH CSESRRTSSA MSGHSRSFLA RELKEISSTS QTLLYLPDLT ESSLGGRNLL PGSHGMGLTQ ADTTSLRTLR ISETSDSSQG QDSESVLLVD EVSGSHREEP ASKGNSLQVT FPSETLKLSE KCI....
| Schlagworte: | Ptger4, Ptgerep4, Prostanoid EP4 receptor, PGE receptor EP4 subtype, PGE2 receptor EP4 subtype, Prostaglandin E2 receptor... |
| Anwendung: | Activity not tested |
| Exprimiert in: | E.coli |
| Ursprungsart: | mouse |
| MW: | 16.6 kD |
ab 496,00 €
NEU
Human PTGER2 Protein, hFc Tag
Artikelnummer: DIM-PME100999.10
Recombinant Human PTGER2 Protein with C-terminal human Fc tag. PTGER2(Met1-Glu23) hFc(Glu99-Ala330), Protein function: Receptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(s) proteins that stimulate adenylate cyclase. Has a relaxing effect on smooth muscle. May play an important role...
| Schlagworte: | EP2 |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| CAS | 12 |
| MW: | 28.7 kD |
ab 144,00 €
NEU
Human PTGER4 Protein, hFc Tag
Artikelnummer: DIM-PME101000.10
Recombinant Human PTGER4 Protein with C-terminal human Fc tag. PTGER4(Met1-Ser19) hFc(Glu99-Ala330), Protein function: Receptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(s) proteins that stimulate adenylate cyclase. Has a relaxing effect on smooth muscle. May play an important role...
| Schlagworte: | EP4, EP4R |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| CAS | 12 |
| MW: | 28.1 kD |
ab 144,00 €
NEU
PTGER4 (human) full length protein-synthetic nanodisc
Artikelnummer: DIM-FLP100097.10
Discover a breakthrough in membrane protein research and drug development with DIMA Biotech's Synthetic Nanodiscs. Traditional methods struggle with challenges in obtaining water-soluble and bioactive forms of multi-transmembrane proteins. Our innovative polymer-based Nanodisc platform offers a game-changing...
| Schlagworte: | PTGER4, PTGER2, Prostanoid EP4 receptor, PGE receptor EP4 subtype, PGE2 receptor EP4 subtype, Prostaglandin E2 receptor... |
| Anwendung: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | 53.1 kD |
ab 1.260,00 €
NEU
Anti-PTGER4
Artikelnummer: CSB-PA002354.50
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
| Schlagworte: | Anti-PTGER2, Anti-PTGER4, Anti-Prostanoid EP4 receptor, Anti-PGE receptor EP4 subtype, Anti-PGE2 receptor EP4 subtype,... |
| Anwendung: | ELISA, WB, IF |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
106,00 €
NEU
Anti-PTGER4
Artikelnummer: CSB-PA826092.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: PTGER4. Antigen Species: Human
| Schlagworte: | Anti-PTGER2, Anti-PTGER4, Anti-Prostanoid EP4 receptor, Anti-PGE receptor EP4 subtype, Anti-PGE2 receptor EP4 subtype,... |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 163,00 €
NEU
Anti-PTGER4
Artikelnummer: CSB-PA949253.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: PTGER4. Antigen Species: Human
| Schlagworte: | Anti-PTGER2, Anti-PTGER4, Anti-Prostanoid EP4 receptor, Anti-PGE receptor EP4 subtype, Anti-PGE2 receptor EP4 subtype,... |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 163,00 €
L-161,982
Artikelnummer: Cay10011565-1
Prostaglandin E2 (PGE2) exerts its effects through four separate G coupled-protein receptors (EP1-4). L-161,982 is a potent and selective EP4 receptor antagonist. It demonstrates selective binding to human EP4 receptors with a Ki value of 0.024 µM compared to other receptors of the prostanoid family, EP1, EP2, EP3,...
| Schlagworte: | N-[[4'-[[3-butyl-1,5-dihydro-5-oxo-1-[2-(trifluoromethyl)phenyl]-4H-1,2,4-triazol-4-yl]methyl][1,1'-biphenyl]-2-yl]sulfony... |
| Anwendung: | EP4 receptor antagonist |
| CAS | 147776-06-5 |
| MW: | 654.7 D |
ab 50,00 €
CAY10598
Artikelnummer: Cay13281-500
Prostaglandin E2 (PGE2) activates four E prostanoid (EP) receptors, EP1-4. EP4 is a Gs protein-coupled receptor that, by elevating the second messenger cAMP, plays important roles in bone formation and resorption, cancer, and atherosclerosis. CAY10598 is a very potent agonist of EP4, binding with a Ki value of 1.2...
| Schlagworte: | 5-[(3S)-3-hydroxy-4-phenyl-1-buten-1-yl]1-[6-(2H-tetrazol-5R-yl)hexyl]-2-pyrrolidinone |
| Anwendung: | EP4 agonist |
| CAS | 346673-06-1 |
| MW: | 383.5 D |
ab 129,00 €
L-902,688
Artikelnummer: Cay10007712-1
Prostaglandin E2 (PGE2) activates four E prostanoid (EP) receptors, EP1-4. EP4 is a Gs protein-coupled receptor that, by elevating the second messenger cAMP, plays important roles in bone formation and resorption, cancer, and atherosclerosis. L-902,688 is a highly potent agonist of the human PGE2 receptor, EP4. It...
| Schlagworte: | 5-[(1E,3R)-4,4-difluoro-3-hydroxy-4-phenyl-1-buten-1-yl]-1-[6-(2H-tetrazol-5R-yl)hexyl]-2-pyrrolidinone |
| Anwendung: | EP4 agonist |
| CAS | 634193-54-7 |
| MW: | 419.5 D |
ab 150,00 €
EP4 Antagonist 14
Artikelnummer: Cay38427-1
EP4 antagonist 14 is an antagonist of the prostaglandin E2 (PGE2) receptor subtype EP4 with an IC50 value of 1.1 nM in a reporter assay using HEK293 cells expressing the human receptor. It inhibits PGE2-induced beta-arrestin recruitment in the same cells (IC50 = 0.9 nM). EP4 antagonist 14 (10 µM) decreases...
| Schlagworte: | PGE2 Receptor 4 Antagonist 14, Prostaglandin E2 Receptor 4 Antagonist 14,... |
| Anwendung: | EP4 receptor (prostaglandin E receptor 4) antagonist |
| MW: | 453.4 D |
ab 90,00 €
AMX12006
Artikelnummer: Cay39027-10
AMX12006 is an antagonist of the prostaglandin E2 (PGE2) receptor subtype EP4 (IC50 = 4.3 nM). It is selective for EP4 over EP1, EP2, and EP3 receptors (IC50s = >10 µM for all). AMX12006 is cytotoxic to MCF-7 and 4T1 breast and CT26 colon cancer cells (IC50s = 46.73, 79.47, and 41.39 µM, respectively). It reduces...
| Schlagworte: | 4-[(1S)-1-[[[1-methyl-3-[[3-(trifluoromethyl)phenyl]amino]-1H-indol-2-yl]carbonyl]amino]ethyl]-benzoic acid |
| Anwendung: | EP4 receptor (prostaglandin E receptor 4) antagonist |
| CAS | 2639775-01-0 |
| MW: | 481.5 D |
ab 77,00 €