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Zu "K04222" wurden 55 Artikel gefunden!
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NEU
Artikelnummer: CSB-EP023068HU.1
Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 1-29aa. Protein Length: Partial. Tag Info: N-terminal GST-tagged. Target Protein Sequence: MDNVLPVDSD LSPNISTNTS EPNQFVQPA. Purity: Greater than 90% as determined by SDS-PAGE. Endotoxin: Not test. Biological Activity: n/a. Form: Liquid or Lyophilized...
Schlagworte: | SPR, NK1R, NK-1R, TACR1, NK-1 receptor, Substance-P receptor, Tachykinin receptor 1, Recombinant Human Substance-P... |
Anwendung: | Activity not tested |
Exprimiert in: | E.coli |
Ursprungsart: | human |
MW: | 30.1 kD |
ab 213,00 €
Artikelnummer: ELK-ELK0600.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Mouse TACR1. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Mouse TACR1. Next,...
Schlagworte: | SPR, Tac1r, Tacr1, NK-1R, NK-1 receptor, Substance-P receptor, Tachykinin receptor 1 |
Anwendung: | ELISA |
Spezies-Reaktivität: | mouse |
ab 365,00 €
Artikelnummer: ELK-ELK1512.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human TACR1. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human TACR1. Next,...
Schlagworte: | SPR, NK1R, TACR1, NK-1R, NK-1 receptor, Substance-P receptor, Tachykinin receptor 1 |
Anwendung: | ELISA |
Spezies-Reaktivität: | human |
ab 365,00 €
Artikelnummer: Cay25207-2.5
Acetylaszonalenin is a fungal metabolite that has been found in A. flavipes. It acts as an antagonist of neurokinin-1 (NK1) receptors, inhibiting binding of substance P (Cay-24035) with a Ki value of 170 µM.Formal Name:...
Schlagworte: | (5aS,13aR,14aS)-5-acetyl-14a-(1,1-dimethyl-2-propen-1-yl)-5a,13a,14,14a-tetrahydro-indolo[3',2':4,5]pyrrolo[2,1-c][1,4]ben... |
Anwendung: | Fungal metabolite, substance-P receptor antagonist |
CAS | 42230-55-7 |
MW: | 415.5 D |
ab 189,00 €
Artikelnummer: Cay14867-10
Aprepitant an antiemetic and antagonist of the neurokinin-1 (NK1) receptor (Ki = 3 nM, IC50 = 0.09 nM for the human receptor). It is selective for NK1 over NK3 receptors (Ki = 454.1 nM for human NK3). In vivo, aprepitant (1 mg/kg) prevents plasma extravasation into the esophagus of guinea pigs induced by substance P...
Schlagworte: | Emend, L-754,030, MK-869, ONO-7436,... |
Anwendung: | NK-1 receptor antagonist |
CAS | 170729-80-3 |
MW: | 534.4 D |
ab 50,00 €
Artikelnummer: Cay24035-5
Substance P is tachykinin neuropeptide that selectively binds to neurokinin 1 (NK1) receptors (Kis = 0.14 and 300 nM for NK1 and NK3, respectively) and has diverse biological activities. It is an endogenous peptide expressed in the central and peripheral nervous systems, including the enteric nervous system and in...
Schlagworte: | substance p, trifluoroacetate salt |
Anwendung: | Endogenous TACR1 ligand, neuropeptide |
CAS | 148470-19-3 |
MW: | 1347.6 D |
ab 60,00 €
Artikelnummer: Cay23906-10
Rolapitant is a potent neurokinin-1 (NK1) receptor antagonist (Ki = 0.66 nM for the human receptor). It is greater than 1,000-fold selective for NK1 over NK2 and NK3 and lacks activity in a panel of 100 receptors, transporters, enzymes, and ion channels. Rolapitant inhibits GR-73632-induced calcium efflux in CHO...
Schlagworte: | (5S,8S)-8-[[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]methyl]-8-phenyl-1,7-diazaspiro[4.5]decan-2-one |
Anwendung: | Antiemetic, Neurokinin NK1 antagonist |
CAS | 552292-08-7 |
MW: | 500.5 D |
ab 43,00 €
Artikelnummer: ARG64207.100
Protein function: This is a receptor for the tachykinin neuropeptide substance P. It is probably associated with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinity of this receptor to tachykinins is: substance P > substance K > neuromedin-K. [The UniProt...
Schlagworte: | Anti-SPR, Anti-NK1R, Anti-TACR1, Anti-NK-1R, Anti-NK-1 receptor, Anti-Substance-P receptor, Anti-Tachykinin receptor 1 |
Anwendung: | ELISA, WB |
Wirt: | Goat |
Spezies-Reaktivität: | human |
784,00 €
Artikelnummer: Cay22064-1
Benzomalvin C is a weak antagonist of the neurokinin-1 (NK1) receptor inhibiting binding of substance P by 46% when used at 100 µg/ml in vitro. It is also a weak inhibitor of indolamine 2,3-dioxygenase (IDO) with an IC50 value of 130 µM for recombinant IDO. It was isolated from Penicillium and contains an epoxide...
Schlagworte: | (2R,3S)-rel-(+)-6'-methyl-3-phenyl-spiro[oxirane-2,7'(13'H)-quinazolino[3,2-a][1,4]benzodiazepine]-5',13'(6'H)-dione |
Anwendung: | TACR1 antagonist |
CAS | 157047-98-8 |
MW: | 395.4 D |
682,00 €
Artikelnummer: G-HUFI02888.96
Anwendung: | ELISA |
Spezies-Reaktivität: | human |
641,00 €
Artikelnummer: LKT-A6368.10
NK1 antagonist.
Schlagworte: | (2R)-[(1R)-3,5-bis(trifluoromethyl)phenylethoxy]-(3S)-(4-fluoro)phenyl-4-(3-oxo-1,2,4-triazol-5-yl)methyl morpholine,... |
Anwendung: | Tachykinin receptor 1 / neurokinin-1 receptor antagonist |
CAS | 170729-80-3 |
MW: | 534.43 D |
ab 123,00 €
Artikelnummer: NSJ-R30769
0.5mg/ml if reconstituted with 0.2ml sterile DI water. The Tachykinin receptor 1 (TACR1), also known as Neurokinin 1 receptor (NK1R) or Substance P receptor (SPR) is a G protein coupled receptor found in the central nervous system and peripheral nervous system. The endogenous ligand for this receptor is Substance P,...
Schlagworte: | Anti-SPR, Anti-NK1R, Anti-NK-1R, Anti-TACR1, Anti-NK-1 receptor, Anti-Substance-P receptor, Anti-Tachykinin receptor 1,... |
Anwendung: | WB |
Wirt: | Rabbit |
Spezies-Reaktivität: | human, mouse, rat |
755,00 €