Zu "K04199" wurden 30 Artikel gefunden!
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NEU
Dersimelagon
Artikelnummer: Cay41468-1
Dersimelagon is an agonist of melanocortin receptor 1 (MC1R). It selectively induces cAMP accumulation in HEK293 cells expressing human MC1R (EC50 = 8.16 nM) over HEK293 cells expressing human MC2R (EC50 = >10,000 nM) but also induces cAMP accumulation in HEK293 cells expressing human MC4R (EC50 = 79.6 nM)....
| Schlagworte: | MT-7117,... |
| Anwendung: | MC1R agonist |
| CAS | 1835256-48-8 |
| MW: | 675.8 D |
ab 90,00 €
NEU
![[Nle4,D-Phe7]-alpha-MSH (acetate)](https://www.biomol.com/media/image/c0/76/db/Cay41548-1_200x200.png "[Nle4,D-Phe7]-alpha-MSH (acetate)")
[Nle4,D-Phe7]-alpha-MSH (acetate)
Artikelnummer: Cay41548-1
[Nle4,D-Phe7]-alpha-Melanocyte-stimulating hormone ([Nle4,D-Phe7]-alpha-MSH) is a peptide agonist of melanocortin receptor 1 (MC1R). It induces cAMP accumulation in mouse L-cells expressing human MC1R (EC50 = 0.5 nM). It also induces tyrosinase activity in mouse melanoma cells. In vivo, [Nle4,D-Phe7]-alpha-MSH (1.8...
| Schlagworte: | [Nle4,D-Phe7]-alpha-Melanocyte-stimulating Hormone, Afamelanotide, Melanotan I, NDP-MSH, NDP-alpha-MSH,... |
| Anwendung: | MC1R peptide agonist |
| CAS | 1566590-77-9 |
| MW: | 1646.9 D |
ab 130,00 €
NEU
MSG606 (trifluoroacetate salt)
Artikelnummer: Cay41550-1
MSG606 is a peptide antagonist of melanocortin receptor 1 (MC1R, IC50 = 17 nM for the human receptor) and a derivative of gamma-melanocyte-stimulating hormone (gamma-MSH). It selectively binds to MC1R over MC3R and MC5R (IC50s = 3,900 and 1,000 nM, respectively, for the human receptors), as well as MC4R at 10 µM....
| Schlagworte: | cyclo(CH2)3CO-Gly-His-D-Phe-Arg-D-Trp-Cys)-Asp-Arg-Phe-Gly-NH2,... |
| Anwendung: | Peptide MC1R antagonist |
| MW: | 1347.5 D |
ab 108,00 €
NEU
hMC1R Agonist 1 (acetate)
Artikelnummer: Cay41560-1
hMC1R agonist 1 is a peptide agonist of melanocortin receptor 1 (MC1R) and a derivative of melanotan-II (Cay-27316). It selectively induces cAMP production in HEK293 cells expressing recombinant human MC1R over those expressing recombinant human MC3R, MC4R, or MC5R (EC50s = 3, 902, 915, and >1,000 nM,...
| Schlagworte: | Ac-Nle-[CHfRWC]-NH2, Ac-Nle-[Cys-His-D-Phe-Arg-Trp-Cys]-NH2,... |
| Anwendung: | Peptide MC1R agonist |
| MW: | 1107.4 D |
ab 137,00 €
Afamelanotide acetate
Artikelnummer: TGM-T7589-100mg
Description: Afamelanotide acetate is a synthetic alpha-melanocyte stimulating hormone analogue and first-in-class melanocortin-1 receptor agonist, used to for Erythropoietic Protoporphyria. Target: Melanocortin Receptor. Smiles:...
| Schlagworte: | afamelanotide |
| Anwendung: | Targets melanocortin 1 receptor (MC1R) |
| CAS | 1566590-77-9 |
| MW: | 1706.9 D |
ab 66,00 €
Bremelanotide Acetate
Artikelnummer: TGM-T7608-100mg
Description: Bremelanotide Acetate (PT-141 Acetate) is an agonist of melanocortin receptor (MCR) . Target: Melanocortin Receptor. Smiles:...
| Schlagworte: | bremelanotide, PT-141 Acetate |
| Anwendung: | Targets melanocortin 4 receptor (MC4R) |
| CAS | 1607799-13-2 |
| MW: | 1085.22 D |
ab 46,00 €
Melanotan I
Artikelnummer: TGM-TP1097-100mg
Description: Melanotan I is a non-specific melanocortin receptor (MCR) agonist, an alpha-melanocyte-stimulating hormone (alpha-MSH) analog, which is injected subcutaneously to increase the amount of melanin in the skin Melanotan I is used as an adjunct to tanning Melanotan I has been used for the prevention of...
| Schlagworte: | [Nle4,D-Phe7]-alpha-MSH, MT-I, Afamelanotide |
| Anwendung: | Targets melanocortin 1 receptor (MC1R) |
| CAS | 75921-69-6 |
| MW: | 1646.85 D |
ab 40,00 €
Melanocyte-stimulating hormone receptor (MC1R)-VLPs,...
Artikelnummer: CSB-MP086369HU.1
Organism: Homo sapiens (Human). Source: Mammalian cell. Expression Region: 1-317aa. Protein Length: Full Length. Tag Info: C-terminal 10xHis-tagged(This tag can be tested only under denaturing conditions). Target Protein Sequence: MAVQGSQRRL LGSLNSTPTA IPQLGLAANQ TGARCLEVSI SDGLFLSLGL VSLVENALVV ATIAKNRNLH...
| Schlagworte: | MSHR, MC1R, MC1-R, MSH-R, Melanocortin receptor 1, Melanocyte-stimulating hormone receptor, Recombinant Human... |
| Anwendung: | Activity not tested |
| Exprimiert in: | Mammalian cells |
| Ursprungsart: | human |
| MW: | 36.1 kD |
ab 562,00 €
Anti-MC1R
Artikelnummer: CSB-PA010093.100
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
| Schlagworte: | Anti-MC1R, Anti-MSHR, Anti-MC1-R, Anti-MSH-R, Anti-Melanocortin receptor 1, Anti-Melanocyte-stimulating hormone receptor,... |
| Anwendung: | ELISA, WB, IF |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 106,00 €
Anti-MC1R
Artikelnummer: CSB-PA122172.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: MC1R. Antigen Species: Human
| Schlagworte: | Anti-MC1R, Anti-MSHR, Anti-MC1-R, Anti-MSH-R, Anti-Melanocortin receptor 1, Anti-Melanocyte-stimulating hormone receptor,... |
| Anwendung: | ELISA, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 163,00 €
Anti-MC1R
Artikelnummer: CSB-PA974732.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: MC1R. Antigen Species: Human
| Schlagworte: | Anti-MC1R, Anti-MSHR, Anti-MC1-R, Anti-MSH-R, Anti-Melanocortin receptor 1, Anti-Melanocyte-stimulating hormone receptor,... |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 163,00 €
Anti-MC1R
Artikelnummer: E-AB-15765.60
This intronless gene encodes the receptor protein for melanocyte-stimulating hormone (MSH). The encoded protein, a seven pass transmembrane G protein coupled receptor, controls melanogenesis. Two types of melanin exist: red pheomelanin and black eumelanin. Gene mutations that lead to a loss in function are...
| Schlagworte: | Anti-MSHR, Anti-MC1R, Anti-MSH-R, Anti-MC1-R, Anti-Melanocortin receptor 1, Anti-Melanocyte-stimulating hormone receptor,... |
| Anwendung: | IHC, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 71,00 €