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Zu "K04197" wurden 54 Artikel gefunden!
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Artikelnummer: TGM-T11934-1mg
Description: Macitentan-d4 (ACT-064992 D4) is a deuterated substitute for Macitentan and can be used as a dual antagonist of the non-peptides ETA and ETB (endothelin receptor).Macitentan-d4 is less toxic than Macitentan, has a longer half-life, and can be used to study endothelin receptor-mediated diseases. Smiles:...
Schlagworte: | Macitentan D4, ACT-064992 D4 |
Anwendung: | GC-MS, LC-MS, internal standard, quantification, dual EDNRA / EDNRB antagonist |
CAS | 1258428-05-5 |
MW: | 592.3 D |
ab 257,00 €
Artikelnummer: TGM-T31744-25mg
Description: Fandosentan potassium is a bio-active chemical. Detailed information has not been published. Target: Others. Smiles: [K].CCc1cc(cc2OCOc12)C1=C(N(c2ccccc2C(F)(F)F)S(=O)(=O)c2ccccc12)C(O)=O , t:13,
Schlagworte: | PD 180988, PD 180988-0016, UNII-14U0D2SA4K |
Anwendung: | Targets endothelin receptor type A (EDNRA) |
CAS | 221246-12-4 |
MW: | 556.57 D |
1.491,00 €
Artikelnummer: TGM-T5458-100mg
Description: Darusentan (Lu-135252) is a potent inhibitor of endothelin signaling and function in large and small arteries. Target: Endothelin Receptor. Smiles: COc1cc(OC)nc(O[C@H](C(O)=O)C(OC)(c2ccccc2)c2ccccc2)n1. References: Liang F, et al. Darusentan is a potent inhibitor of endothelin signaling and function in...
Schlagworte: | Lu-135252 |
Anwendung: | ETA receptor antagonist |
CAS | 171714-84-4 |
MW: | 410.43 D |
ab 45,00 €
Artikelnummer: TGM-T73820-5mg
Description: Bosentan-d4, the deuterium-labeled variant of Bosentan, serves as a competitive dual antagonist against endothelin-1 (ET) by targeting both ET A and ET B receptors. It exhibits binding affinities with K i values of 4.7 nM for ET A and 95 nM for ET B in human SMC. Smiles:...
Anwendung: | GC-MS, LC-MS, internal standard |
CAS | 1065472-77-6 |
MW: | 555.64 D |
674,00 €
Artikelnummer: TGM-TMPH-01294-100ug
Description: Receptor for endothelin-1. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of binding affinities for ET-A is: ET1 > ET2 >> ET3.
Schlagworte: | EDNRA, ETRA, ETA, Endothelin-1 receptor, ET-A, ETA-R, hET-AR |
MW: | 8.8 kD |
ab 226,00 €
Artikelnummer: TGM-TQ0270-10mg
Description: Atrasentan hydrochloride (ABT-627 hydrochloride) is an endothelin receptor antagonist with an IC50 of 55.1 µM for ETA. Target: Endothelin Receptor. Smiles: Cl.CCCCN(CCCC)C(=O)CN1C[C@@H]([C@H]([C@@H]1c1ccc(OC)cc1)C(O)=O)c1ccc2OCOc2c1. References: Banerjee S, et al. In vitro and in vivo molecular evidence...
Schlagworte: | A-147627 hydrochloride, ABT-627 hydrochloride, (+)-A 127722 hydrochloride |
Anwendung: | Targets endothelin receptor type A (EDNRA) |
CAS | 195733-43-8 |
MW: | 547.08 D |
ab 41,00 €
Artikelnummer: TGM-T6792-100mg
Description: BQ-123 is a selective endothelin A receptor (ETA) antagonist with IC50 of 7.3 nM. Phase 2. Target: Endothelin Receptor. Smiles: [H][C@@]12CCCN1C(=O)[C@@]([H])(CC(O)=O)NC(=O)[C@@H](Cc1c[nH]c3ccccc13)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](NC2=O)C(C)C. References: Ihara M, et al. J Cardiovasc Pharmacol. 1992, 12,...
Schlagworte: | BQ123 |
Anwendung: | Endothelin receptor A antagonist |
CAS | 136553-81-6 |
MW: | 610.7 D |
ab 78,00 €
Artikelnummer: CSB-CF007403HU.100
Organism: Homo sapiens (Human). Source: in vitro E.coli expression system. Expression Region: 21-427aa. Protein Length: Full Length of Mature Protein. Tag Info: C-terminal 10xHis-tagged. Target Protein Sequence: DNPERYSTNL SNHVDDFTTF RGTELSFLVT THQPTNLVLP SNGSMHNYCP QQTKITSAFK YINTVISCTI FIVGMVGNAT LLRIIYQNKC...
Schlagworte: | ETA, ET-A, ETA-R, hET-AR, Endothelin-1 receptor, Endothelin receptor type A, Recombinant Human Endothelin-1 receptor (EDNRA) |
Anwendung: | Activity not tested |
Exprimiert in: | E.coli in vitro |
Ursprungsart: | human |
MW: | 48.5 kD |
ab 1.413,00 €
Artikelnummer: CSB-YP007403HU1.1
Organism: Homo sapiens (Human). Source: Yeast. Expression Region: 21-80aa. Protein Length: Partial. Tag Info: N-terminal 6xHis-tagged. Target Protein Sequence: DNPERYSTNL SNHVDDFTTF RGTELSFLVT THQPTNLVLP SNGSMHNYCP QQTKITSAFK. Purity: Greater than 90% as determined by SDS-PAGE. Endotoxin: Not test. Biological...
Schlagworte: | ETA, ET-A, ETA-R, hET-AR, Endothelin-1 receptor, Endothelin receptor type A, Recombinant Human Endothelin-1 receptor... |
Anwendung: | Activity not tested |
Exprimiert in: | Yeast |
Ursprungsart: | human |
MW: | 8.8 kD |
ab 235,00 €
Artikelnummer: CSB-PA002447.100
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
Schlagworte: | Anti-ETA, Anti-ET-A, Anti-ETA-R, Anti-hET-AR, Anti-Endothelin-1 receptor, Anti-Endothelin receptor type A, Ednra antibody,... |
Anwendung: | ELISA, WB, IHC, IF |
Wirt: | Rabbit |
Spezies-Reaktivität: | human, mouse, monkey |
ab 106,00 €
Artikelnummer: CSB-PA002449.100
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
Schlagworte: | Anti-ETA, Anti-ET-A, Anti-ETA-R, Anti-hET-AR, Anti-Endothelin-1 receptor, Anti-Endothelin receptor type A, Ednra antibody,... |
Anwendung: | ELISA, WB, IF |
Wirt: | Rabbit |
Spezies-Reaktivität: | human, mouse, rat |
ab 106,00 €
Artikelnummer: CSB-PA299262.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: EDNRA. Antigen Species: Human
Schlagworte: | Anti-ETA, Anti-ET-A, Anti-ETA-R, Anti-hET-AR, Anti-Endothelin-1 receptor, Anti-Endothelin receptor type A, Ednra antibody,... |
Anwendung: | ELISA, WB, IHC |
Wirt: | Rabbit |
Spezies-Reaktivität: | human, mouse |
ab 163,00 €