Zu "K04189" wurden 180 Artikel gefunden!
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Motixafortide
Artikelnummer: TGM-T14665-25mg
Description: Motixafortide (BKT140 4-fluorobenzoyl) is a CXCR4 antagonist with an IC50 of 1 nM. Target: CXCR. Smiles:...
| Schlagworte: | BL-8040, BKT140 (4-fluorobenzoyl), TF14016 |
| Anwendung: | Targets C-X-C chemokine receptor type 4 (CXCR4, CD184) |
| CAS | 664334-36-5 |
| MW: | 2159.52 D |
ab 732,00 €
MSX-122
Artikelnummer: TGM-T3992-100mg
Description: MSX-122 is a novel small molecule and partial CXCR4 antagonist, with potent inhibition of CXCR4/CXCL12 actions(IC50 = 10 nM). Target: CXCR. Smiles: C(Nc1ncccn1)c1ccc(CNc2ncccn2)cc1. References: Liang Z, et al. Development of a unique small molecule modulator of CXCR4. PLoS One. 2012,7(4):e34038.
| Schlagworte: | MSX122, MSX 122 |
| Anwendung: | CXCR4 partial antagonist |
| CAS | 897657-95-3 |
| MW: | 292.34 D |
ab 57,00 €
AMD 3465 hexahydrobromide
Artikelnummer: TGM-T7208-100mg
Description: AMD 3465 hexahydrobromide (GENZ-644494 (hexahydrobromide)) is a CXCR4 receptor antagonist with potential anticancer and anti-HIV activity. Target: HIV Protease, CXCR. Smiles: Br.Br.Br.Br.Br.Br.C(NCc1ccccn1)c1ccc(CN2CCCNCCNCCC NCC2)cc1. References: Hatse S, et al. AMD3465, a monomacrocyclic CXCR4...
| Schlagworte: | GENZ-644494 (hexahydrobromide) |
| Anwendung: | CXCL12 inhibitor, CXCR4 antagonist |
| CAS | 185991-07-5 |
| MW: | 896.07 D |
ab 34,00 €
CXCR4 Protein, Human, Recombinant (hFc)
Artikelnummer: TGM-TMPJ-01037-10ug
Description: C-X-C chemokine receptor type 4 (CXCR4) is an alpha-chemokine receptor specific for stromal-derived-factor-1 (SDF-1 also called CXCL12), a molecule endowed with potent chemotactic activity for lymphocytes. This receptor is one of several chemokine receptors that HIV isolates can use to infect CD4+ T...
| Schlagworte: | CXCR4,CD184,Fusin,D2S201E,FB22,HM89,HSY3RR,LAP3,LCR1,LESTR,NPY3R,NPYR,NPYRL,NPYY3R,WHIM |
| MW: | 45 kD |
ab 135,00 €
CXCR4 Protein, Human, Recombinant
Artikelnummer: TGM-TMPY-06553-100ug
Description: CXCR4 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 39.75 kDa and the accession number is P61073-1.
| Schlagworte: | FB22, NPYR, LAP3, LAP-3, WHIM, NPY3R, LCR1, CD184, LESTR, WHIMS, HM89, HSY3RR, NPYRL, D2S201E, chemokine (C-X-C motif)... |
| MW: | 39.75 kD |
ab 821,00 €
Mavorixafor
Artikelnummer: TGM-TQ0174-100mg
Description: Mavorixafor (AMD-070) is an effective and selective antagonist of CXCR4, with an IC50 value of 13 nM against CXCR4 125I-SDF binding. Mavorixafor inhibits the replication of T-tropic HIV-1 (NL4.3 strain) in MT-4 cells (IC50 = 1 nM) and PBMCs (IC50 = 9 nM). Target: CXCR. Smiles:...
| Schlagworte: | AMD-070 |
| Anwendung: | Targets C-X-C chemokine receptor type 4 (CXCR4, CD184) |
| CAS | 558447-26-0 |
| MW: | 349.47 D |
ab 63,00 €
Balixafortide
Artikelnummer: TGM-TP2141L-100mg
Description: Balixafortide (POL6326) is a potent, selective, and well-tolerated peptidic CXCR4 antagonist with an IC50 < 10 nM, and also acts as a potent hematopoietic stem and progenitor cell (HSPC) mobilizing agent. It demonstrates anti-cancer effects[1][2], blocks beta-arrestin recruitment and calcium flux with...
| Schlagworte: | POL6326 |
| Anwendung: | Targets C-X-C chemokine receptor type 4 (CXCR4, CD184) |
| CAS | 1051366-32-5 |
| MW: | 1864.14 D |
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WZ811
Artikelnummer: TGM-T1739-100mg
Description: WZ811 is a novel and effective small molecular CXCR4 antagonist (EC50: 0.3 nM). Target: CXCR. Smiles: C(Nc1ccccn1)c1ccc(CNc2ccccn2)cc1. References: Zhan W, et al. J Med Chem, 2007, 50(23), 5655-5664.
| Anwendung: | CXCR4 antagonist |
| CAS | 55778-02-4 |
| MW: | 290.36 D |
ab 48,00 €
Plerixafor
Artikelnummer: TGM-T1776-100mg
Description: Plerixafor (AMD-3329), a chemokine receptor antagonist, blocks the binding of stromal cell-derived factor (SDF-1alpha) to the cellular receptor CXCR4. Target: CXCR, HIV Protease, Virus Protease. Smiles: C(N1CCCNCCNCCC NCC1)c1ccc(CN2CCCNCCNCCCNCC2)cc1. References: Zabel BA, et al. J Immunol. 2009,...
| Schlagworte: | AMD 3100, JM3100, AMD-3329 |
| Anwendung: | Targets C-X-C chemokine receptor type 4 (CXCR4, CD184) |
| CAS | 110078-46-1 |
| MW: | 502.78 D |
ab 42,00 €
NUCC-390 dihydrochloride
Artikelnummer: TGM-T63004-1mg
Description: NUCC-390 dihydrochloride, a novel and selective CXCR4 receptor agonist, effectively induces the internalization of CXCR4 receptors and acts antagonistically to AMD3100 [1]. This small-molecule compound has demonstrated the ability to facilitate functional nerve recovery following neurodegeneration in...
| Anwendung: | CXCR4 agonist |
| CAS | 2749281-71-6 |
| MW: | 468.46 D |
ab 193,00 €
C-X-C chemokine receptor type 4 (CXCR4), partial, human,...
Artikelnummer: CSB-EP006254HU1.1
Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 303-352aa. Protein Length: Partial of Isoform 2. Tag Info: N-terminal 10xHis-SUMO-tagged and C-terminal Myc-tagged. Target Protein Sequence: PILYAFLGAK FKTSAQHALT SVSRGSSLKI LSKGKRGGHS SVSTESESSS. Purity: Greater than 90% as determined by SDS-PAGE....
| Schlagworte: | LCR1, FB22, HM89, Fusin, LAP-3, NPYRL, CD184, LESTR, CXCR4, CXC-R4, CXCR-4, SDF-1 receptor, LPS-associated protein 3,... |
| Anwendung: | Activity not tested |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 25.2 kD |
ab 213,00 €
C-X-C chemokine receptor type 4 (CXCR4), partial, human,...
Artikelnummer: CSB-EP006254HU1c0.1
Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 303-352aa. Protein Length: Partial of Isoform 2. Tag Info: N-terminal 6xHis-GST-tagged. Target Protein Sequence: PILYAFLGAK FKTSAQHALT SVSRGSSLKI LSKGKRGGHS SVSTESESSS. Purity: Greater than 85% as determined by SDS-PAGE. Endotoxin: n/a. Biological...
| Schlagworte: | LCR1, FB22, HM89, Fusin, LAP-3, NPYRL, CD184, LESTR, CXCR4, CXC-R4, CXCR-4, SDF-1 receptor, LPS-associated protein 3,... |
| Anwendung: | Activity not tested |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 36.7 kD |
ab 213,00 €