Zu "K04180" wurden 175 Artikel gefunden!
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TAK-220
Artikelnummer: TGM-T16973-100mg
Description: TAK-220 is a selective and orally bioavailable CCR5 antagonist with IC50 values of 3.5 nM for RANTES binding inhibition and 1.4 nM for MIP-1alpha binding inhibition to CCR5. Target: HIV Protease. Smiles: CC(=O)N1CCC(CC1)C(=O)N(CCCN1CCC(Cc2ccc(cc2)C(N)=O)CC1)c1ccc(C)c(Cl)c1. References: Takashima K, et...
| Anwendung: | CCR5 antagonist |
| CAS | 333994-00-6 |
| MW: | 553.14 D |
ab 339,00 €
Ancriviroc
Artikelnummer: TGM-T30047-100mg
Description: Ancriviroc(CHEMBL336672), an imidoxime with strong antiretroviral activity, is a potent CCR5 inhibitor that can be used to study HIV. Target: HIV Protease. Smiles: C(=N/OCC)(\C1CCN(CC1)C2(C)CCN(C(=O)C3=C(C)N(=O)=CC=C3C)CC2)/C4=CC=C(Br)C=C4. References: Xu M, et al. Inhibitory effects of Schisandrin C on...
| Schlagworte: | SCH-351125, Schering C, [3H]ancriviroc, CHEMBL336672, AC1NUILE |
| Anwendung: | Targets C-C chemokine receptor type 5 (CCR5, CD195) |
| CAS | 370893-06-4 |
| MW: | 557.52 D |
ab 190,00 €
Vicriviroc maleate
Artikelnummer: TGM-T3435-100mg
Description: Vicriviroc maleate (SCH-417690 (maleate))(Sch-417690) is a piperazine-based CCR5 receptor antagonist with activity against human immunodeficiency virus. The IC50 value is 0.91 nM in clinical development for the treatment of HIV-1. Target: HIV Protease, CCR. Smiles:...
| Schlagworte: | SCH-417690 (maleate), SCH-D (maleate) |
| Anwendung: | Targets C-C chemokine receptor type 5 (CCR5, CD195) |
| CAS | 599179-03-0 |
| MW: | 649.7 D |
ab 58,00 €
Aplaviroc hydrochloride
Artikelnummer: TGM-T26642-25mg
Description: Aplaviroc is a human cellular CC chemokine receptor 5 (CCR5) entry inhibitor. Aplaviroc binds specifically to CCR5 and demonstrates potent anti-human immunodeficiency virus activity in vitro in the subnanomolar range. In vitro studies show that aplaviroc selectively inhibits the binding of a particular...
| Schlagworte: | AK 602, AK602, Aplaviroc HCl, AK-602, GW873140, GW-873140, GW873140A |
| Anwendung: | Targets C-C chemokine receptor type 5 (CCR5, CD195) |
| CAS | 461023-63-2 |
| MW: | 614.17 D |
ab 1.118,00 €
Fuscin
Artikelnummer: TGM-T37714-5mg
Description: Fuscin is a quinonoid fungal metabolite originally isolated from O. fuscum that has diverse biological activities. It inhibits binding of the ADP/ATP translocase inhibitor atractyloside to rat liver mitochondria in an ADP-dependent manner when used at a concentration of 50 µM in a radioligand binding...
| Anwendung: | Human CCR5 antagonist |
| CAS | 83-85-2 |
| MW: | 276.288 D |
2.208,00 €
TAK-779
Artikelnummer: TGM-T7499-100mg
Description: TAK-779 (Takeda 779) is an antagonist of chemokine receptor 5 (CCR5), CCR2b, and CXC chemokine receptor 3 (CXCR3). Target: CXCR, HIV Protease, CCR. Smiles: [Cl-].Cc1ccc(cc1)-c1ccc2CCCC(=Cc2c1)C(=O)Nc1ccc(C[N+](C)(C)C2CCOCC2)cc1. References: Suzaki Y , Hamada K , Nomi T , et al. A small-molecule...
| Schlagworte: | Takeda 779 |
| Anwendung: | CCR5 / CCR2b / CXCR3 antagonist |
| CAS | 229005-80-5 |
| MW: | 531.13 D |
ab 38,00 €
Anti-CD195, clone RoAb13, Phycoerythrin conjugated
Artikelnummer: E-AB-F1418D.100
CD195, also known as CCR5, is a 45 kD G protein-coupled seven transmembrane CC-chemokine receptor. It binds to MIP-1alpha, MIP-1beta, and RANTES and is expressed on a subset of T cells and monocytes. CCR5 mediates an intracellular signal thought to induce cell differentiation and proliferation. CCR5 has also been...
| Schlagworte: | Anti-CCR5, Anti-CD195, Anti-CCR-5, Anti-CMKBR5, Anti-CHEMR13, Anti-CC-CKR-5, Anti-C-C CKR-5, Anti-HIV-1 fusion coreceptor,... |
| Anwendung: | FCM |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
ab 99,00 €
Anti-CD195, clone RoAb13, Elab Fluor(R)647 conjugated
Artikelnummer: E-AB-F1418M.100
CD195, also known as CCR5, is a 45 kD G protein-coupled seven transmembrane CC-chemokine receptor. It binds to MIP-1alpha, MIP-1beta, and RANTES and is expressed on a subset of T cells and monocytes. CCR5 mediates an intracellular signal thought to induce cell differentiation and proliferation. CCR5 has also been...
| Schlagworte: | Anti-CCR5, Anti-CD195, Anti-CCR-5, Anti-CMKBR5, Anti-CHEMR13, Anti-CC-CKR-5, Anti-C-C CKR-5, Anti-HIV-1 fusion coreceptor,... |
| Anwendung: | FCM |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
ab 116,00 €
Anti-CD195, clone RoAb13, Elab Fluor(R)488 conjugated
Artikelnummer: E-AB-F1418L.100
CD195, also known as CCR5, is a 45 kD G protein-coupled seven transmembrane CC-chemokine receptor. It binds to MIP-1alpha, MIP-1beta, and RANTES and is expressed on a subset of T cells and monocytes. CCR5 mediates an intracellular signal thought to induce cell differentiation and proliferation. CCR5 has also been...
| Schlagworte: | Anti-CCR5, Anti-CD195, Anti-CCR-5, Anti-CMKBR5, Anti-CHEMR13, Anti-CC-CKR-5, Anti-C-C CKR-5, Anti-HIV-1 fusion coreceptor,... |
| Anwendung: | FCM |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
ab 116,00 €
C-C chemokine receptor type 5 (CCR5), human, recombinant
Artikelnummer: CSB-CF004844HU.100
Organism: Homo sapiens (Human). Source: in vitro E.coli expression system. Expression Region: 1-352aa. Protein Length: Full Length. Tag Info: N-terminal 10xHis-tagged. Target Protein Sequence: MDYQVSSPIY DINYYTSEPC QKINVKQIAA RLLPPLYSLV FIFGFVGNML VILILINCKR LKSMTDIYLL NLAISDLFFL LTVPFWAHYA AAQWDFGNTM CQLLTGLYFI...
| Schlagworte: | CCR5, CCR-5, CD195, CMKBR5, CHEMR13, CC-CKR-5, C-C CKR-5, HIV-1 fusion coreceptor, C-C chemokine receptor type 5,... |
| Anwendung: | Activity not tested |
| Exprimiert in: | E.coli in vitro |
| Ursprungsart: | human |
| MW: | 43.9 kD |
ab 914,00 €
C-C chemokine receptor type 5 (CCR5)-VLPs, human,...
Artikelnummer: CSB-MP004844HU.1
Organism: Homo sapiens (Human). Source: Mammalian cell. Expression Region: 1-352aa. Protein Length: Full Length. Tag Info: C-terminal 10xHis-tagged(This tag can be tested only under denaturing conditions). Target Protein Sequence: MDYQVSSPIY DINYYTSEPC QKINVKQIAA RLLPPLYSLV FIFGFVGNML VILILINCKR LKSMTDIYLL...
| Schlagworte: | CCR5, CCR-5, CD195, CMKBR5, CHEMR13, CC-CKR-5, C-C CKR-5, HIV-1 fusion coreceptor, C-C chemokine receptor type 5,... |
| Anwendung: | Activity not tested |
| Exprimiert in: | Mammalian cells |
| Ursprungsart: | human |
| MW: | 42.3 kD |
ab 510,00 €
C-C chemokine receptor type 5 (Ccr5), partial, mouse,...
Artikelnummer: CSB-YP004844MO.1
Organism: Mus musculus (Mouse). Source: Yeast. Expression Region: 263-354aa. Protein Length: Partial. Tag Info: N-terminal 6xHis-tagged. Target Protein Sequence: QEFFGLNNCS SSNRLDQAMQ ATETLGMTHC CLNPVIYAFV GEKFRSYLSV FFRKHMVKRF CKRCSIFQQD NPDRASSVYT RSTGEHEVST GL. Purity: Greater than 90% as determined by SDS-PAGE....
| Schlagworte: | Ccr5, CCR-5, CD195, Cmkbr5, CC-CKR-5, C-C CKR-5, MIP-1 alpha receptor, C-C chemokine receptor type 5, Recombinant Mouse... |
| Anwendung: | Activity not tested |
| Exprimiert in: | Yeast |
| Ursprungsart: | mouse |
| MW: | 12.6 kD |
ab 283,00 €