Zu "K04177" wurden 46 Artikel gefunden!

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NEU
C-C chemokine receptor type 2 (Ccr2), partial, mouse, recombinant
C-C chemokine receptor type 2 (Ccr2), partial, mouse,...

Artikelnummer: CSB-EP004841MO1.1

Organism: Mus musculus (Mouse). Source: E.coli. Expression Region: 1-55aa. Protein Length: Partial. Tag Info: N-terminal 10xHis-tagged and C-terminal Myc-tagged. Target Protein Sequence: MEDNNMLPQF IHGILSTSHS LFTRSIQELD EGATTPYDYD DGEPCHKTSV KQIGA. Purity: Greater than 90% as determined by SDS-PAGE. Endotoxin: Not...
Schlagworte: Ccr2, CCR2, CD192, CCR-2, Cmkbr2, CC-CKR-2, C-C CKR-2, MCP-1 receptor, JE/FIC receptor, C-C chemokine receptor type 2,...
Anwendung: Activity not tested
Exprimiert in: E.coli
Ursprungsart: mouse
MW: 13.6 kD
ab 354,00 €
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NEU
Anti-CCR2 antibody(DMC447), IgG1 Chimeric mAb
Anti-CCR2 antibody(DMC447), IgG1 Chimeric mAb

Artikelnummer: DIM-DMC100447.10

Protein function: Key functional receptor for CCL2 but can also bind CCL7 and CCL12 (PubMed:8146186, PubMed:8048929, PubMed:23408426). Its binding with CCL2 on monocytes and macrophages mediates chemotaxis and migration induction through the activation of the PI3K cascade, the small G protein Rac and lamellipodium...
Schlagworte: Anti-CC-CKR-2, Anti-MCP-1-R, Anti-CD192, Anti-CCR2 antibody(DMC447), IgG1 Chimeric mAb
Wirt: Rabbit
Spezies-Reaktivität: human
CAS 12
ab 139,00 €
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NEU
Human CCR2 Protein, hFc Tag
Human CCR2 Protein, hFc Tag

Artikelnummer: DIM-PME100922.10

Recombinant Human CCR2 with C-terminal human Fc tag. CCR2(Met1-Ala42) hFc(Glu99-Ala330), Protein function: Key functional receptor for CCL2 but can also bind CCL7 and CCL12 (PubMed:8146186, PubMed:8048929, PubMed:23408426). Its binding with CCL2 on monocytes and macrophages mediates chemotaxis and migration...
Schlagworte: CC-CKR-2, CCR-2, CCR2A, CCR2B, CD192, CKR2, CKR2A, CKR2B, CMKBR2, MCP-1-R
Exprimiert in: Human cells
Ursprungsart: human
CAS 12
MW: 31.0 kD
ab 95,00 €
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NEU
Human CCR2 Protein, mFc Tag
Human CCR2 Protein, mFc Tag

Artikelnummer: DIM-PME101109.10

Recombinant human CCR2 protein with C-terminal mouse Fc tag. CCR2(Met1-Ala42) mFc(Pro99-Lys330), Protein function: Key functional receptor for CCL2 but can also bind CCL7 and CCL12 (PubMed:8146186, PubMed:8048929, PubMed:23408426). Its binding with CCL2 on monocytes and macrophages mediates chemotaxis and migration...
Schlagworte: CC-CKR-2, MCP-1-R, CD192
Exprimiert in: Human cells
Ursprungsart: human
CAS 12
MW: 31.1 kD
ab 144,00 €
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NEU
CCR2 (human) full length protein-synthetic nanodisc
CCR2 (human) full length protein-synthetic nanodisc

Artikelnummer: DIM-FLP100028.10

Discover a breakthrough in membrane protein research and drug development with DIMA Biotech's Synthetic Nanodiscs. Traditional methods struggle with challenges in obtaining water-soluble and bioactive forms of multi-transmembrane proteins. Our innovative polymer-based Nanodisc platform offers a game-changing...
Schlagworte: CCR2, CD192, CCR-2, CMKBR2, MCP-1-R, CC-CKR-2, C-C CKR-2, C-C chemokine receptor type 2, Monocyte chemoattractant protein...
Anwendung: Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization
Exprimiert in: Human cells
Ursprungsart: human
MW: 41.9 kD
ab 1.260,00 €
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NEU
Mouse CCR2 Protein, hFc Tag
Mouse CCR2 Protein, hFc Tag

Artikelnummer: DIM-PME-M100107.10

Recombinant mouse CCR2 protein with C-terminal human Fc tag. Mouse CCR2(Met1-Ala55) hFc(Glu99-Ala330), Protein function: Key functional receptor for CCL2 but can also bind CCL7 and CCL12 chemokines (PubMed:8631787, PubMed:8662823, PubMed:8996246). Its binding with CCL2 on monocytes and macrophages mediates...
Schlagworte: Ckr2, Ccr2a, Ccr2b, Ckr2a, Ckr2b, mJe-r, Cmkbr2, Cc-ckr-2
Exprimiert in: Human cells
Ursprungsart: mouse
MW: 32.3 kD
ab 98,00 €
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NEU
CCR2 (human) full length protein-MNP
CCR2 (human) full length protein-MNP

Artikelnummer: DIM-FLP200028.100

Plasma membrane-coated nanoparticles (MNPs) have been used in various applications, including delivery of therapeutic agents and induction of immune responses et al. Unlike the conventional strategies, MNPs directly leverage intact and natural functions of cell membranes, and show high biocompatibility, specificity,...
Schlagworte: CCR2, CD192, CCR-2, CMKBR2, MCP-1-R, CC-CKR-2, C-C CKR-2, C-C chemokine receptor type 2, Monocyte chemoattractant protein...
Anwendung: Full length transmembrane protein, high biocompatib., ELISA, screening, immunization, cell-based assays
Exprimiert in: Human cells
Ursprungsart: human
MW: 41.9 kD
ab 1.680,00 €
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Human CCR2 (Chemokine C-C-Motif Receptor 2) ELISA Kit
Human CCR2 (Chemokine C-C-Motif Receptor 2) ELISA Kit

Artikelnummer: ELK-ELK2930.48

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human CCR2. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human CCR2. Next,...
Schlagworte: CCR2, CCR-2, CD192, CMKBR2, MCP-1-R, CC-CKR-2, C-C CKR-2, C-C chemokine receptor type 2, Monocyte chemoattractant protein...
Anwendung: ELISA
Spezies-Reaktivität: human
ab 365,00 €
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Mouse CCR2 (Chemokine C-C-Motif Receptor 2) ELISA Kit
Mouse CCR2 (Chemokine C-C-Motif Receptor 2) ELISA Kit

Artikelnummer: ELK-ELK5338.48

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Mouse CCR2. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Mouse CCR2. Next,...
Schlagworte: CCR2, Ccr2, CCR-2, CD192, Cmkbr2, CC-CKR-2, C-C CKR-2, MCP-1 receptor, JE/FIC receptor, C-C chemokine receptor type 2
Anwendung: ELISA
Spezies-Reaktivität: mouse
ab 365,00 €
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Anti-CCR2 (Plozalizumab Biosimilar Antibody)
Anti-CCR2 (Plozalizumab Biosimilar Antibody)

Artikelnummer: G-HDBS0080.100

Protein function: Key functional receptor for CCL2 but can also bind CCL7 and CCL12 (PubMed:8146186, PubMed:8048929, PubMed:23408426). Its binding with CCL2 on monocytes and macrophages mediates chemotaxis and migration induction through the activation of the PI3K cascade, the small G protein Rac and lamellipodium...
Schlagworte: Anti-CCR2, Anti-CCR-2, Anti-CD192, Anti-CMKBR2, Anti-MCP-1-R, Anti-CC-CKR-2, Anti-C-C CKR-2, Anti-C-C chemokine receptor...
Anwendung: FC
Wirt: Human
Spezies-Reaktivität: human
399,00 €
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RS 504393
RS 504393

Artikelnummer: Cay17330-1

RS 504393 is a selective antagonist of the MCP-1 receptor CCR2 (IC50s = 89 nM and >100 µM for CCR2 and CCR1, respectively). It has been shown to inhibit MCP-1-stimulated chemotaxis (IC50 = 330 nM) and ischemia-reperfusion injury in kidneys.Formal Name:...
Schlagworte: 6-methyl-1'-[2-(5-methyl-2-phenyl-4-oxazolyl)ethyl]-spiro[4H-3,1-benzoxazine-4,4'-piperidin]-2(1H)-one
Anwendung: CCR2 chemokine receptor antagonist
CAS 300816-15-3
MW: 417.5 D
ab 61,00 €
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MK-0812
MK-0812

Artikelnummer: Cay21803-5

MK-0812 is an antagonist of chemokine (C-C) motif receptor 2 (CCR2, IC50 = 5 nM for the human receptor). It inhibits mammosphere formation of BT-549 breast cancer cells, an effect that is enhanced by the beta-catenin inhibitor PNU 74654 (Cay-16349). MK-0812 (0.03, 0.1, and 0.3 mg/kg) increases chemokine (C-C) motif...
Schlagworte: 1,5-anhydro-2,3-dideoxy-3-[[(1R,3S)-...
Anwendung: CCR2 antagonist
CAS 624733-88-6
MW: 469.5 D
ab 98,00 €
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