Zu "K04176" wurden 32 Artikel gefunden!
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CCR1 antagonist 8
Artikelnummer: TGM-T14899-100mg
Description: CCR1 antagonist 8, a third azaindazole series compound, is a CCR1 antagonist (IC50: 1.8 nM in Ca2+ flux assay). Target: CCR. Smiles: CS(=O)(=O)c1cc(ccn1)C1(CC1)NC(=O)c1cncc2n(ncc12)-c1ccc(F)cc1. References: Harcken C, et al. Identification of novel azaindazole CCR1 antagonist clinical candidates. Bioorg...
| Anwendung: | CCR1 antagonist |
| CAS | 1295298-26-8 |
| MW: | 451.47 D |
ab 1.059,00 €
BI-639667
Artikelnummer: Cay41523-1
BI-639667 is a chemokine (C-C motif) receptor 1 (CCR1) antagonist. It inhibits calcium flux induced by chemokine (C-C motif) ligand 3 (CCL3) in cells expressing CCR1 (IC50 = 2 nM). BI-639667 also inhibits RANTES-induced chemotaxis in THP-1 cells (IC50 = 2 nM).Formal Name:...
| Schlagworte: | 1-(4-fluorophenyl)-N-[1-[2-(methylsulfonyl)-4-pyridinyl]cyclopropyl]-1H-pyrazolo[3,4-c]pyridine-4-carboxamide |
| Anwendung: | CCR1 antagonist |
| CAS | 1295298-26-8 |
| MW: | 451.5 D |
ab 85,00 €
C-C chemokine receptor type 1 (Ccr1), mouse, recombinant
Artikelnummer: CSB-CF004839MO.100
Organism: Mus musculus (Mouse). Source: in vitro E.coli expression system. Expression Region: 1-355aa. Protein Length: Full Length. Tag Info: N-terminal 10xHis-tagged. Target Protein Sequence: MEISDFTEAY PTTTEFDYGD STPCQKTAVR AFGAGLLPPL YSLVFIIGVV GNVLVILVLM QHRRLQSMTS IYLFNLAVSD LVFLFTLPFW IDYKLKDDWI FGDAMCKLLS...
| Schlagworte: | Ccr1, CCR1, CD191, CCR-1, Cmkbr1, RANTES-R, CC-CKR-1, C-C CKR-1, MIP-1alpha-R, C-C chemokine receptor type 1, Macrophage... |
| Anwendung: | Activity not tested |
| Exprimiert in: | E.coli in vitro |
| Ursprungsart: | mouse |
| MW: | 43.7 kD |
ab 1.413,00 €
C-C chemokine receptor type 1 (CCR1), partial, human,...
Artikelnummer: CSB-EP004839HU1.1
Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 306-355aa. Protein Length: Partial. Tag Info: N-terminal 6xHis-SUMO-tagged. Target Protein Sequence: ERFRKYLRQL FHRRVAVHLV KWLPFLSVDR LERVSSTSPS TGEHELSAGF. Purity: Greater than 85% as determined by SDS-PAGE. Endotoxin: Not test. Biological Activity:...
| Schlagworte: | CCR1, CD191, HM145, CCR-1, CMKBR1, RANTES-R, CC-CKR-1, C-C CKR-1, MIP-1alpha-R, LD78 receptor, C-C chemokine receptor type... |
| Anwendung: | Activity not tested |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 18.9 kD |
ab 240,00 €
Anti-CCR1 antibody(DMC465), IgG1 Chimeric mAb
Artikelnummer: DIM-DMC100465.10
Protein function: Receptor for a C-C type chemokine. Binds to MIP-1-alpha, MIP- 1-delta, RANTES, and MCP-3 and, less efficiently, to MIP-1-beta or MCP- 1 and subsequently transduces a signal by increasing the intracellular calcium ions level. Responsible for affecting stem cell proliferation. [The UniProt Consortium]
| Schlagworte: | Anti-CD191, Anti-CKR-1, Anti-CKR1, Anti-CMKBR1, Anti-HM145, Anti-MIP1aR, Anti-SCYAR1, Anti-CCR1 antibody(DMC465), IgG1... |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
| CAS | 12 |
ab 139,00 €
Human CCR1 Protein, hFc Tag
Artikelnummer: DIM-PME100921.10
Recombinant human CCR1 protein with C-terminal human Fc tag. CCR1(Met1-Ala34) hFc(Glu99-Ala330), Protein function: Receptor for a C-C type chemokine. Binds to MIP-1-alpha, MIP- 1-delta, RANTES, and MCP-3 and, less efficiently, to MIP-1-beta or MCP- 1 and subsequently transduces a signal by increasing the...
| Schlagworte: | CD191, CKR-1, CKR1, CMKBR1, HM145, MIP1aR, SCYAR1 |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| CAS | 12 |
| MW: | 30.0 kD |
ab 95,00 €
CCR1 (human) full length protein-synthetic nanodisc
Artikelnummer: DIM-FLP100094.10
Discover a breakthrough in membrane protein research and drug development with DIMA Biotech's Synthetic Nanodiscs. Traditional methods struggle with challenges in obtaining water-soluble and bioactive forms of multi-transmembrane proteins. Our innovative polymer-based Nanodisc platform offers a game-changing...
| Schlagworte: | CCR1, HM145, CD191, CCR-1, CMKBR1, RANTES-R, CC-CKR-1, C-C CKR-1, MIP-1alpha-R, LD78 receptor, C-C chemokine receptor type... |
| Anwendung: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | 41.2 kD |
ab 1.260,00 €
Mouse CCR1 (Chemokine C-C-Motif Receptor 1) ELISA Kit
Artikelnummer: ELK-ELK4010.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Mouse CCR1. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Mouse CCR1. Next,...
| Schlagworte: | CCR1, Ccr1, CD191, CCR-1, Cmkbr1, CC-CKR-1, RANTES-R, C-C CKR-1, MIP-1alpha-R, C-C chemokine receptor type 1, Macrophage... |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | mouse |
ab 365,00 €
Human CCR1 (Chemokine C-C-Motif Receptor 1) ELISA Kit
Artikelnummer: ELK-ELK4621.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human CCR1. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human CCR1. Next,...
| Schlagworte: | CCR1, HM145, CD191, CCR-1, CMKBR1, CC-CKR-1, RANTES-R, C-C CKR-1, MIP-1alpha-R, LD78 receptor, C-C chemokine receptor type... |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
ab 365,00 €
Anti-CCR1
Artikelnummer: NSJ-R32913
0.5mg/ml if reconstituted with 0.2ml sterile DI water. C-C chemokine receptor type 1 is a protein that in humans is encoded by the CCR1 gene. This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. The ligands of...
| Schlagworte: | Anti-Ccr1, Anti-CCR1, Anti-CCR-1, Anti-CD191, Anti-Cmkbr1, Anti-CC-CKR-1, Anti-RANTES-R, Anti-C-C CKR-1,... |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | rat |
755,00 €
BX 471
Artikelnummer: Cay18503-1
The CC chemokine receptor-1 (CCR1), whose ligands include macrophage inflammatory protein-1alpha (MIP-1alpha), RANTES, and monocyte chemotactic protein-3 (MCP-3), has a central role in leukocyte trafficking and is highly expressed in certain autoimmune diseases. BX 471 is a nonpeptide CCR1 antagonist that has been...
| Schlagworte: | N-[5-chloro-2-[2-[(2R)-4-[(4-fluorophenyl)methyl]-2-methyl-1-piperazinyl]-2-oxoethoxy]phenyl]-urea |
| Anwendung: | CCR1 antagonist |
| CAS | 217645-70-0 |
| MW: | 434.9 D |
ab 60,00 €
Anti-CCR1
Artikelnummer: NSJ-F48896-0.08ML
In 1X PBS, pH 7.4, with 0.09% sodium azide. CCR1 encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. The ligands of this receptor include macrophage inflammatory protein 1 alpha (MIP-1 alpha), regulated on activation...
| Schlagworte: | Anti-CCR1, Anti-CCR-1, Anti-CD191, Anti-HM145, Anti-CMKBR1, Anti-RANTES-R, Anti-CC-CKR-1, Anti-C-C CKR-1,... |
| Anwendung: | WB, IHC, FC, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 326,00 €