Zu "K04160" wurden 56 Artikel gefunden!
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Mosapride Citrate
Artikelnummer: TGM-T6597-100mg
Description: Mosapride Citrate (TAK-370 citrate), a gastroprokinetic agent, utilizes as a selective 5HT4 agonist. Target: 5-HT Receptor. Smiles: OC(=O)CC(O)(CC(O)=O)C(O)=O.CCOc1cc(N)c(Cl)cc1C(=O)NCC1CN(Cc2ccc(F)cc2)CCO1. References: Nonogaki K, Kaji T. Diabetes Res Clin Pract. 2015 Dec,110(3):e18-21.
| Schlagworte: | AS-4370, TAK-370 citrate, AS-4370 citrate |
| Anwendung: | Serotonin receptor subtype 5-HT4 agonist |
| CAS | 112885-42-4 |
| MW: | 614.02 D |
ab 43,00 €
Mosapride citrate dihydrate
Artikelnummer: TGM-T6597L-5mg
Description: Mosapride Citrate is a 5-HT4 receptor agonist used to stimulate gastrointestinal motility via acetylcholine. Mosapride Citrate facilitates acetylcholine release from the enteric cholinergic neurons. Target: Others. Smiles: O.OC(=O)CC(O)(CC(O)=O)C(O)=O.CCOc1cc(N)c(Cl)cc1C(=O)NCC1CN(Cc2ccc(F)cc2)CCO1....
| Schlagworte: | Mosapride Citrate, GR-107719-B, GR 107719 B, AS 4370, TAK-370, AS-4370 |
| Anwendung: | Targets 5-hydroxytryptamine receptor 4 (HTR4) |
| CAS | 636582-62-2 |
| MW: | 632.04 D |
98,00 €
FK-1052 HCl
Artikelnummer: TGM-T71045-100mg
Description: FK-1052 HCl is a serotonin 3 & 4 dual receptor antagonist. Target: Others. Smiles: Cl.Cc1nc[nH]c1C[C@H]1CCc2c(C)c3ccccc3n2C1=O
| Anwendung: | Targets 5-hydroxytryptamine receptor 3 (HTR3) |
| CAS | 129299-90-7 |
| MW: | 329.83 D |
ab 1.520,00 €
Prucalopride Succinate
Artikelnummer: TGM-T6958-100mg
Description: Prucalopride Succinate (Resolor Succinate) is a selective, high affinity 5-HT4 receptor agonist, inhibiting human 5-HT(4a) and 5-HT(4b) receptor with Ki value of 2.5 nM and 8 nM, respectively. Target: 5-HT Receptor. Smiles: OC(=O)CCC(O)=O.COCCCN1CCC(CC1)NC(=O)C1=C2OCCC2=C(N)C(Cl)=C1. References: Briejer...
| Schlagworte: | R-108512, Resolor Succinate |
| Anwendung: | Targets 5-hydroxytryptamine receptor 4 (HTR4) |
| CAS | 179474-85-2 |
| MW: | 485.96 D |
ab 31,00 €
Mosapride
Artikelnummer: TGM-T8128-100mg
Description: Mosapride (AS-4370) is a selective 5HT4 agonist. Target: 5-HT Receptor. Smiles: C(NCC1CN(CC2=CC=C(F)C=C2)CCO1)(=O)C3=C(OCC)C=C(N)C(Cl)=C3. References: Odaka T, et al. Serotonin 5- HT4 receptor agonist (mosapride citrate). Nihon Rinsho. 2006 Aug,64(8):1491-4.
| Schlagworte: | AS-4370, TAK-370 |
| Anwendung: | Targets 5-hydroxytryptamine receptor 4 (HTR4) |
| CAS | 112885-41-3 |
| MW: | 421.89 D |
ab 38,00 €
Relenopride
Artikelnummer: TGM-T83981-100mg
Description: Relenopride (YKP 10811) is a selective 5-HT4 receptor agonist that promotes intestinal motility and is used in the study of intestinal disorders. Target: 5-HT Receptor. Smiles: C(NCC1CCN(CC[C@H](OC(N)=O)C2=CC=C(F)C=C2)CC1)(=O)C3=C(OC)C=C(N)C(Cl)=C3. References: Shin A, et al. A randomized trial of...
| Schlagworte: | SKL-IBS, YKP 10811 |
| Anwendung: | Targets 5-hydroxytryptamine receptor 4 (HTR4) |
| CAS | 1221416-43-8 |
| MW: | 492.97 D |
ab 128,00 €
Naronapride
Artikelnummer: TGM-T63785-100mg
Description: Naronapride (ATI-7505) is a potent 5-HT4 receptor agonist, useful for studying gastrointestinal disorders. Target: Others. Smiles: C(N[C@H]1[C@@H](OC)CN(CCCCCC(O[C@@H]2C3CCN(C2)CC3)=O)CC1)(=O)C4=C(OC)C=C(N)C(Cl)=C4
| Anwendung: | Targets 5-hydroxytryptamine receptor 4 (HTR4) |
| CAS | 860174-12-5 |
| MW: | 537.09 D |
ab 2.142,00 €
PF-04995274
Artikelnummer: TGM-T16481-100mg
Description: PF-04995274 is an effective, high-affinity, and partial serotonin 4 receptor (5-HT4R) agonist. PF-04995274 is brain penetrant and can be used for cognitive disorders associated with Alzheimer's disease. PF-04995274 has an EC50 range of 0.26-0.47 nM for human 5-HT4A/4B/4D/4E (Ki range of 0.15-0.46 nM)....
| Anwendung: | 5-HT4A / 5-HT4B / 5-HT4D / 5-HT4E partial agonist |
| CAS | 1331782-27-4 |
| MW: | 432.51 D |
ab 31,00 €
Tegaserod maleate
Artikelnummer: TGM-T1551-100mg
Description: Tegaserod maleate (SDZ-HTF-919) is a 5-HT4 agonist manufactured by Novartis for managing irritable bowel syndrome and constipation. It was the only drug approved by the United States Food and Drug Administration for relieving abdominal discomfort, bloating, and constipation associated with irritable...
| Schlagworte: | HTF-919, SDZ-HTF-919 |
| Anwendung: | Targets 5-hydroxytryptamine receptor 4 (HTR4) |
| CAS | 189188-57-6 |
| MW: | 417.46 D |
ab 40,00 €
Velusetrag
Artikelnummer: TGM-T35046-100mg
Description: Velusetrag(TD-5108)is an effective, selective, and highly potent agonist of the 5-HT4 receptor, and being developed for the treatment of gastroparesis, chronic constipation, and irritable bowel syndrome. Target: Others. Smiles:...
| Schlagworte: | TD5108, TD 5108, TD-5108 |
| Anwendung: | Targets 5-hydroxytryptamine receptor 4 (HTR4) |
| CAS | 866933-46-2 |
| MW: | 504.64 D |
ab 1.140,00 €
Relenopride hydrochloride
Artikelnummer: TGM-T28512-100mg
Description: Relenopride, a 5-HT agonist, is used potentially for the treatment of chronic constipation. Target: Others. Smiles: Cl.COc1cc(N)c(Cl)cc1C(=O)NCC1CCN(CC[C@H](OC(N)=O)c2ccc(F)cc2)CC1. References: Nusrat S, Miner PB Jr. New pharmacological treatment options for irritable bowel syndrome with constipation....
| Schlagworte: | YKP-10811, YKP10811, YKP 10811, Relenopride HCl |
| Anwendung: | Targets 5-hydroxytryptamine receptor 4 (HTR4) |
| CAS | 1221416-42-7 |
| MW: | 529.43 D |
ab 916,00 €
Felcisetrag
Artikelnummer: TGM-T28934-100mg
Description: Felcisetrag (TD-8954) is a potent and selective orally active 5-HT4 agonist with gastrointestinal prokinetic properties.Felcisetrag shows high affinity for the human recombinant 5-HT4(c) (h5-HT4(c)) receptor with a pKi of 9.4. Target: 5-HT Receptor. Smiles:...
| Schlagworte: | TD-8954, TD 8954, TD8954 |
| Anwendung: | Targets 5-hydroxytryptamine receptor 4 (HTR4) |
| CAS | 916075-84-8 |
| MW: | 455.59 D |
ab 156,00 €