Zu "K04153" wurden 224 Artikel gefunden!
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SB-224289 hydrochloride
Artikelnummer: TGM-T12841-10mg
Description: SB-224289 hydrochloride (SB-224289A) is a selective antagonist of 5-HT1B receptor, with anxiolytic effect. Target: 5-HT Receptor. Smiles: Cl.CN1CCC2(COc3cc4CCN(C(=O)c5ccc(cc5)-c5ccc(cc5C)-c5noc(C)n5)c4cc23)CC1. References: Cassilly CD, et al. SB-224289 Antagonizes the Antifungal Mechanism of the Marine...
| Schlagworte: | SB-224289A |
| Anwendung: | 5-HT1B inverse agonist |
| CAS | 180084-26-8 |
| MW: | 557.08 D |
ab 49,00 €
Vilazodone-d8
Artikelnummer: TGM-T13300-1mg
Description: Vilazodone D8 is a deuterium-labeled vilazodone. Vilazodone is a combined inhibitor of serotonin specific reuptake (SSRI) and agonist of 5-HT1A receptor partial. Smiles: [2H]C1([2H])N(CCCCc2c[nH]c3ccc(cc23)C#N)C([2H])([2H])C([2H])([2H])N(c2ccc3oc(cc3c2)C(N)=O)C1([2H])[2H]
| Anwendung: | Serotonin antagonist and reuptake inhibitor (SARI), GC-MS, LC-MS, internal standard |
| CAS | 1794789-93-7 |
| MW: | 449.57 D |
ab 344,00 €
NAN-190 hydrobromide
Artikelnummer: TGM-T12172-100mg
Description: NAN-190 hydrobromide is an antagonist of serotonin receptor 5-HT. Target: 5-HT Receptor. Smiles: Br.COc1ccccc1N1CCN(CCCCN2C(=O)c3ccccc3C2=O)CC1. References: Shahane SA, et al. Detection of phospholipidosis induction: a cell-based assay in high-throughput and high-content format. J Biomol Screen. 2014...
| Anwendung: | 5-HT1A receptor mixed antagonist / partial agonist |
| CAS | 115338-32-4 |
| MW: | 474.39 D |
ab 34,00 €
Naluzotan
Artikelnummer: TGM-T16265-1mg
Description: Naluzotan(PRX 00023) is a novel and potent 5-HT1A agonist with IC50 and Ki values of approximately 20 nM and 5.1 nM, respectively.Naluzotan is a potent hERG K+ channel blocker with an IC50 value of 3800 nM.Naluzotan exhibits anxiolytic activity and can be used to study depression. Target: EGFR, 5-HT...
| Schlagworte: | PRX 00023 |
| Anwendung: | Targets 5-hydroxytryptamine receptor 1 (HTR1) |
| CAS | 740873-06-7 |
| MW: | 450.64 D |
ab 700,00 €
Rizatriptan
Artikelnummer: TGM-T1734L-5mg
Description: Rizatriptan is an agonist of the serotonin-1b and serotonin-1d receptor. Target: Others. Smiles: CN(C)CCc1c[nH]c2ccc(Cn3cncn3)cc12. References: Tradtrantip L, Jin BJ, Yao X, Anderson MO, Verkman AS. Aquaporin-Targeted Therapeutics: State-of-the-Field. Adv Exp Med Biol. 2017,969:239-250. doi:...
| Schlagworte: | Risatriptan, MK 462 free base |
| Anwendung: | Targets 5-hydroxytryptamine receptor 1 (HTR1) |
| CAS | 144034-80-0 |
| MW: | 269.34 D |
970,00 €
Pizotifen
Artikelnummer: TGM-T1442-100mg
Description: Pizotifen (Pizotyline) is a strong serotonin and tryptamine antagonist, with weak anticholinergic, anti-histaminic and anti-kinin effects. It also possesses sedative and appetite-stimulating properties. Pizotifen hydrochloride is an active ingredient in Sandomigran, which is used for the prophylactic...
| Schlagworte: | Pizotyline, BC-105 |
| Anwendung: | Targets 5-hydroxytryptamine receptor 2 (HTR2) |
| CAS | 15574-96-6 |
| MW: | 295.44 D |
ab 37,00 €
Rizatriptan benzoate
Artikelnummer: TGM-T1512-100mg
Description: Rizatriptan benzoate (MK-462 Benzoate) selectively binds to and activates serotonin (5-HT) 1B receptors and 5-HT 1D receptors providing relief of migraine headaches. Target: 5-HT Receptor. Smiles: c1cccc(c1)C(=O)O.[nH]1cc(c2cc(ccc12)Cn1ncnc1)CCN(C)C. References: Williamson DJ, et al. Br J...
| Schlagworte: | MK-462 Benzoate |
| Anwendung: | Targets 5-hydroxytryptamine receptor 1 (HTR1) |
| CAS | 145202-66-0 |
| MW: | 391.47 D |
ab 40,00 €
Flesinoxan
Artikelnummer: TGM-T16711-100mg
Description: Flesinoxan, a hypotensive agent, is an effective, high-affinity, and selective 5-hydroxytryptamine1A receptor agonist (EC50: 24 nM). Target: 5-HT Receptor. Smiles: OC[C@@H]1COc2c(O1)cccc2N1CCN(CCNC(=O)c2ccc(F)cc2)CC1. References: Hadrava V, et al. Characterization of 5-hydroxytryptamine1A properties of...
| Anwendung: | Targets 5-hydroxytryptamine receptor 1 (HTR1) |
| CAS | 98206-10-1 |
| MW: | 415.46 D |
ab 371,00 €
1-(1-Naphthyl) piperazine hydrochloride
Artikelnummer: TGM-T21569-100mg
Description: 1-(1-Naphthyl) piperazine hydrochloride (1-naphthalen-1-ylpiperazine hydrochloride) is a serotonergic ligand which could bind nonselectively with multiple serotonin (5-HT) receptors. Target: Others. Smiles: Cl.C1CN(CCN1)C1=CC=CC2=CC=CC=C12. References: Lee M , Rangisetty J B , Pullagurla M R , et al....
| Schlagworte: | 1-(Naphthalen-1-yl)piperazine hydrochloride, 1-naphthalen-1-ylpiperazine hydrochloride |
| Anwendung: | 5-HT1 serotonin receptor agonist, 5-HT2 serotonin receptor antagonist |
| CAS | 104113-71-5 |
| MW: | 248.75 D |
ab 51,00 €
Cinitapride
Artikelnummer: TGM-T21385-1mg
Description: Cinitapride (Blaston) is a gastroprokinetic agent. It slows the actions of the muscles to reduce the symptoms of conditions such as acid reflux, delayed gastric emptying, and ulcer dyspepsia. Cinitapride acts as an antagonist of the 5-HT2 receptors and as an agonist of the 5-HT1 and 5-HT4 receptors....
| Schlagworte: | Cintapro, Cinmove, cinitapride tartrate, Cidine, Paxapride, Blaston |
| Anwendung: | Targets 5-hydroxytryptamine receptor 1 (HTR1) |
| CAS | 66564-14-5 |
| MW: | 402.49 D |
ab 71,00 €
Methysergide maleate
Artikelnummer: TGM-T21423-1mg
Description: Methysergide is used for prophylaxis of migraine headaches/cluster headaches but is no longer recommended due to retropulmonary/retroperitoneal fibrosis. It may also be used in the treatment of serotonin syndrome. It is also used in carcinoid syndrome to treat severe diarrhea. Target: Others. Smiles:...
| Schlagworte: | UML 491, Deseril, Sansert, UML491, Methysergide, UML-491 |
| Anwendung: | Targets 5-hydroxytryptamine receptor 1 (HTR1) |
| CAS | 129-49-7 |
| MW: | 469.54 D |
ab 79,00 €
Xaliproden
Artikelnummer: TGM-T35152-25mg
Description: Xaliproden is a biochemical. Target: Others. Smiles: FC(F)(F)C1=CC=CC(=C1)C2=CCN(CCC=3C=CC=4C=CC=CC4C3)CC2. References: Ng L, Khan F, Young CA, Galea M. Symptomatic treatments for amyotrophic lateral sclerosis/motor neuron disease. Cochrane Database Syst Rev. 2017 Jan 10,1:CD011776. doi:...
| Schlagworte: | SR 57746, SR-57746, SR57746 |
| Anwendung: | Targets 5-hydroxytryptamine receptor 1 (HTR1) |
| CAS | 135354-02-8 |
| MW: | 381.43 D |
1.521,00 €