Zu "K04146" wurden 66 Artikel gefunden!
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SB-277011 dihydrochloride
Artikelnummer: TGM-T12861L-10mg
Description: SB-277011 dihydrochloride is a potent, selective, orally bioavailable and brain penetrate antagonist of dopamine D3 receptor(pKis of 8.0, 6.0, <5.2 and 5.9 for D3, D2, 5-HT1B, and 5-HT1D receptors, respectively). Target: Dopamine Receptor. Smiles:...
| Schlagworte: | SB-277011A dihydrochloride |
| Anwendung: | DRD3 antagonist |
| CAS | 1226917-67-4 |
| MW: | 511.49 D |
ab 108,00 €
BP 897 hydrochloride
Artikelnummer: TGM-T14767-100mg
Description: BP 897 is a potent and selective agonist of dopamine D3 receptor and it is a weak dopamine D2 receptor antagonist, with Kis of 0.92 nM and 61 nM for D3 and D2 receptors. Which shows low affinities at D1 and D4 receptors (Kis, 3 and 0.3 µM, respectively). Target: Dopamine Receptor. Smiles:...
| Anwendung: | Dopamine D3 receptor partial agonist |
| CAS | 314776-92-6 |
| MW: | 454 D |
ab 31,00 €
Pramipexole dihydrochloride
Artikelnummer: TGM-T1476L-10mg
Description: Pramipexole dihydrochloride could be used to treat Parkinson disease. Target: Dopamine Receptor. Smiles: Cl.Cl.CCCN[C@H]1CCc2nc(N)sc2C1
| Anwendung: | Galphai agonist |
| CAS | 104632-25-9 |
| MW: | 247.79 D |
ab 31,00 €
FAUC-365
Artikelnummer: TGM-T21667-1mg
Description: FAUC-365 is a D3 dopamine receptor agonist. Target: Dopamine Receptor. Smiles: Clc1cccc(N2CCN(CCCCNC(=O)c3cc4ccccc4s3)CC2)c1Cl. References: Bettinetti L, Schlotter K, Hübner H, Gmeiner P. Interactive SAR studies:rational discovery of super-potent and highly selective dopamine D3 receptor antagonists and...
| Schlagworte: | FAUC-365 Benzo[b]thiophene-2-carboxylic acid {4-[4-(2,3-dichloro- phenyl)-piperazin-1-yl]-butyl}-amide, FAUC-365... |
| Anwendung: | Dopamine D3 receptor antagonist |
| CAS | 474432-66-1 |
| MW: | 462.44 D |
ab 48,00 €
Piribedil
Artikelnummer: TGM-T3278-100mg
Description: Piribedil (Trivastan) is a dopamine D2 agonist, used in the treatment of Parkinson's disease. Target: Dopamine Receptor, Histone Methyltransferase, Adrenergic Receptor. Smiles: C(N1CCN(CC1)C1=NC=CC=N1)C1=CC2=C(OCO2)C=C1. References: Millan MJ et al. The Journal of Pharmacology and Experimental...
| Schlagworte: | ET-495, EU-4200, Trivastan, Trivastal |
| Anwendung: | Dopamine receptor agonist |
| CAS | 3605-01-4 |
| MW: | 298.34 D |
ab 49,00 €
Fluoroclebopride
Artikelnummer: TGM-T3187-100mg
Description: Fluoroclebopride is a dopamine (DA) D2 receptor ligand. Target: Dopamine Receptor. Smiles: C(NC1CCN(CC2=CC=C(F)C=C2)CC1)(=O)C3=C(OC)C=C(N)C(Cl)=C3. References: Michael A Nader, et al. Neuropsychopharmacology, Volume 21, Issue 4, October 1999, Pages 589-596
| Anwendung: | PET, dopamine receptor binding |
| CAS | 154540-49-5 |
| MW: | 391.87 D |
ab 31,00 €
ML417
Artikelnummer: TGM-T8423-100mg
Description: ML417 is a selective and brain-penetrant agonist of D3 dopamine (EC50: 38 nM). Target: Dopamine Receptor, Arrestin. Smiles: COc1ccc(OCCN2CCN(CC2)C(=O)c2cc3ccccc3[nH]2)cc1. References: Moritz AE, et al. Discovery, Optimization, and Characterization of ML417: A Novel and Highly Selective D3 Dopamine...
| Anwendung: | Dopamine D3 receptor agonist |
| CAS | 1386162-69-1 |
| MW: | 379.45 D |
ab 34,00 €
Dopamine D3 Receptor Agonist 13a
Artikelnummer: TGM-T83776-10mg
Description: Dopamine D3 receptor agonist 13a selectively targets the dopamine D3 receptor over dopamine D1, D2, and D4 receptors, with affinities (Ki values) of 0.14, 4,600, 2.85, and 756 nM, respectively. It also interacts with serotonin (5-HT) receptor subtypes 5-HT1A, 5-HT2A, 5-HT2B, and 5-HT2C, with Ki values...
| Anwendung: | Dopamine D3 receptor agonist |
| CAS | 2899250-94-1 |
| MW: | 442.42 D |
ab 88,00 €
Anti-DRD3
Artikelnummer: CSB-PA005795.50
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
| Schlagworte: | Anti-DRD3, Anti-Dopamine D3 receptor, Anti-D(3) dopamine receptor, 3dopamine receptor antibody, D antibody, D(3) dopamine... |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
126,00 €
Pimozide
Artikelnummer: Cay16222-50
Pimozide is a dopamine receptor antagonist (Kis = 2.4, 0.3, and 1.8 nM for D2, D3, and D4 receptors, respectively). It also binds to eight additional receptors (Kds = 25-3,100 nM for the human receptors) and inhibits the voltage-gated sodium channel Nav1.2 and the voltage-gated potassium channel Kv11.1 (IC50s = 42...
| Schlagworte: | NSC 170984, R 6238, 1-[1-[4,4-bis(4-fluorophenyl)butyl]-4-piperidinyl]-1,3-dihydro-2H-benzimidazol-2-one |
| Anwendung: | Dopamine D2/D3-receptor antagonist |
| CAS | 2062-78-4 |
| MW: | 461.6 D |
ab 44,00 €
Fluspirilene
Artikelnummer: Cay19530-5
Fluspirilene is a dopamine D2 and D3 receptor antagonist (Kis = 1.5 and 1.1 nM, respectively). It is selective for dopamine D2 and D3 receptors over dopamine D1, alpha1- and alpha2-adrenergic, H1 histamine, and sigma-1 (sigma1) receptors (Kis = 450, 102, >5,000, 540, and 150 nM, respectively), muscarinic...
| Schlagworte: | McN-JR 6218, R 6218, Redeptin, 8-[4,4-bis(4-fluorophenyl)butyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one |
| Anwendung: | Calcium channel blocker, dopamine receptor antagonist |
| CAS | 1841-19-6 |
| MW: | 475.6 D |
ab 99,00 €
Amisulpride
Artikelnummer: Cay14619-25
Amisulpride is a dopamine D2 and D3 receptor antagonist (Kis = 3 and 3.5 nM, respectively). It is also an antagonist of the serotonin (5-HT) receptor subtypes 5-HT2B, 5-HT7, and 5-HT7A (Kis = 13, 11.5, and 135.5 nM, respectively). It is selective for these receptors over a panel of 39 additional receptors, ion...
| Schlagworte: | DAN 2163, 4-amino-N-[(1-ethyl-2-pyrrolidinyl)methyl]-5-(ethylsulfonyl)-2-methoxy-benzamide |
| Anwendung: | D2 and D3 dopamine receptor antagonist, 5-HT2B and 5-HT7 serotonin receptor antagonist |
| CAS | 71675-85-9 |
| MW: | 369.5 D |
ab 61,00 €