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Zu "K04144" wurden 46 Artikel gefunden!
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NEU
Artikelnummer: CSB-EP007178HU1.1
Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 338-446aa. Protein Length: Partial. Tag Info: N-terminal 6xHis-tagged. Target Protein Sequence: RKAFSTLLGC YRLCPATNNA IETVSINNNG AAMFSSHHEP RGSISKECNL VYLIPHAVGS SEDLKKEEAA GIARPLEKLS PALSVILDYD TDVSLEKIQP ITQNGQHPT. Purity: Greater than 90% as...
Schlagworte: | DRD1, Dopamine D1 receptor, D(1A) dopamine receptor, Recombinant Human D (1A) dopamine receptor (DRD1), partial |
Anwendung: | Activity not tested |
Exprimiert in: | E.coli |
Ursprungsart: | human |
MW: | 17.8 kD |
ab 240,00 €
Artikelnummer: ELK-ELK8646.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Mouse DRD1. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Mouse DRD1. Next,...
Schlagworte: | Drd1, Drd1a, Dopamine D1 receptor, D(1A) dopamine receptor |
Anwendung: | ELISA |
Spezies-Reaktivität: | mouse |
ab 365,00 €
Artikelnummer: ELK-ELK1868.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human DRD1. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human DRD1. Next,...
Schlagworte: | DRD1, Dopamine D1 receptor, D(1A) dopamine receptor |
Anwendung: | ELISA |
Spezies-Reaktivität: | human |
ab 365,00 €
Artikelnummer: Cay16094-10
(-)-Apomorphine is a non-selective dopamine receptor agonist that exhibits pKi values of 6.43, 7.08, 7.59, 8.36, and 7.83 for human recombinant D1, D2L, D3, D4, and D5 receptors, respectively. It produces biphasic effects on locomotor activity and displays anti-Parkinsonian and neuroprotective actions.Formal Name:...
Schlagworte: | NSC 11442, Uprima, 5,6,6aR,7-tetrahydro-6-methyl-4H-dibenzo[de,g]quinoline-10,11-diol, monohydrochloride |
Anwendung: | Dopamine receptor agonist |
CAS | 58117-94-5 |
MW: | 303.8 D |
ab 43,00 €
Artikelnummer: Cay15631-10
SCH 23390 is a halobenzazepine that acts as a selective antagonist of the dopamine D1-like receptor subtypes D1 and D5 (Kis = 0.2 and 0.3 nM, respectively). In vivo studies have demonstrated that SCH 23390 can abolish pharmacologically-induced seizures. This compound is useful for studying the role of the dopamine...
Schlagworte: | 8-chloro-2,3,4,5-tetrahydro-3-methyl-5R-phenyl-1H-3-benzazepin-7-ol, monohydrochloride |
Anwendung: | Dopamine receptor D1 / D5 antagonist |
CAS | 125941-87-9 |
MW: | 324.2 D |
ab 189,00 €
Artikelnummer: Cay15067-10
(±)-SKF 81297 is a selective agonist of the dopamine D1-like receptor (Ki = 1.9 nM). It demonstrates comparatively lower binding affinity for the dopamine D2, dopamine D3, serotonin 5-HT2A, and adrenergic alpha2 receptors (Kis = 1,272, >10,000, 955, and 509 nM, respectively). Activation of dopamine D1-like receptors...
Schlagworte: | (±)-6-chloro-PB, 6-chloro-2,3,4,5-tetrahydro-1-phenyl-1H-3-benzazepine-7,8-diol, monohydrobromide |
Anwendung: | Dopamine D1-like receptor agonist |
CAS | 67287-39-2 |
MW: | 370.7 D |
ab 130,00 €
Artikelnummer: Cay24316-1
A-77636 is a dopamine D1 receptor agonist (Ki = 40 nM). It induces activity equal to or greater than dopamine (Cay-21992) in an adenylate cyclase assay of D1 receptor activity in fish retina and rat caudate putamen (EC50s = 7.4 and 1.1 nM, respectively) but does not show agonist activity at D2 receptors expressed in...
Schlagworte: | (1R,3S)-1-(aminomethyl)-3,4-dihydro-3-tricyclo[3.3.1.13,7]dec-1-yl-1H-2-benzopyran-5,6-diol, monohydrochloride |
Anwendung: | Dopamine D1 receptor agonist |
CAS | 145307-34-2 |
MW: | 365.9 D |
ab 60,00 €
Artikelnummer: Cay25331-1
SCH 39166 is a dopamine D1 receptor antagonist (Ki = 5 nM). It is selective for D1 over D2-4 receptors (Kis = 3,751, >1,000, and 5,934 nM, respectively), however, it also binds to D5 receptors (Ki = 4.4 nM). SCH 39166 inhibits food intake in a dose-dependent manner in rats (ED50 = 0.84 mg/kg). It reduces ethanol...
Schlagworte: | 11-chloro-7-methyl-6,6alphaS,7,8,9,13betaR-hexahydro-5H-benzo[d]naphtho[2,1-beta]azepin-12-ol, monohydrobromide |
Anwendung: | D1 receptor antagonist |
CAS | 1227675-51-5 |
MW: | 394.7 D |
ab 54,00 €
Artikelnummer: Cay24961-100
Zuclopenthixol is a dopamine receptor antagonist (Kis = 9.8 and 1.5 nM for D1 and D2 receptors, respectively). It also binds to serotonin (5-HT) receptor subtypes 5-HT2 and 5-HT6, alpha1-adrenergic, and histamine receptors (Kis = 7.6, 3, 33, and 169 nM, respectively) but not alpha2-adrenergic receptors (Ki = >4,300...
Schlagworte: | cis-Clopenthixol, Cisordinol, 4-[(3Z)-3-(2-chloro-9H-thioxanthen-9-ylidene)propyl]-1-piperazineethanol |
Anwendung: | Dopamine receptor antagonist |
CAS | 53772-83-1 |
MW: | 401 D |
ab 84,00 €
Artikelnummer: Cay29033-5
SKF 82958 is a dopamine D1 receptor agonist (K0.5 = 4 nM in a radioligand binding assay). It is selective for dopamine D1 over D2 receptors (K0.5 = 73 nM). SKF 82958 induces dopamine D1 receptor-dependent adenylate cyclase activity in rat striatal membranes (EC50 = 491 nM). SKF 82958 (3 mg/kg) prevents and reverses...
Schlagworte: | (±)-6-chloro-APB, 6-chloro-2,3,4,5-tetrahydro-1-phenyl-3-(2-propen-1-yl)-1H-3-benzazepine-7,8-diol, monohydrobromide |
Anwendung: | Dopamine D1 receptor agonist |
CAS | 74115-01-8 |
MW: | 410.7 D |
ab 163,00 €
Artikelnummer: Cay29480-5
SKF 83566 is a dopamine D1 receptor antagonist. In vivo, SKF 83566 (0.005, 0.01, and 0.03 mg/kg) reduces dexbenzetimide- and scopolamine-induced locomotor stereotypy in rats. It decreases ghrelin-induced increases in novel object exploration and food intake in rats when administered at a dose of 100 µg/kg. SKF 83566...
Schlagworte: | 8-bromo-2,3,4,5-tetrahydro-3-methyl-5-phenyl-1H-3-benzazepin-7-ol, monohydrobromide |
Anwendung: | Dopamine D1 receptor antagonist |
CAS | 108179-91-5 |
MW: | 413.2 D |
ab 84,00 €
Artikelnummer: Cay19530-10
Fluspirilene is a dopamine D2 and D3 receptor antagonist (Kis = 1.5 and 1.1 nM, respectively). It is selective for dopamine D2 and D3 receptors over dopamine D1, alpha1- and alpha2-adrenergic, H1 histamine, and sigma-1 (sigma1) receptors (Kis = 450, 102, >5,000, 540, and 150 nM, respectively), muscarinic...
Schlagworte: | McN-JR 6218, R 6218, Redeptin, 8-[4,4-bis(4-fluorophenyl)butyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one |
Anwendung: | Calcium channel blocker, dopamine receptor antagonist |
CAS | 1841-19-6 |
MW: | 475.6 D |
ab 97,00 €