Zu "K04140" wurden 56 Artikel gefunden!
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Miquelianin
Artikelnummer: TGM-TQ0188-5mg
Description: Miquelianin (Quercetin 3-glucuronide) is a potent stilbene oxidase inhibitor, it has antioxidant, anti-atherogenic, and anti-inflammatory activities. Target: Endogenous Metabolite, stilbene oxidase. Smiles: O[C@H]1[C@H](Oc2c(oc3cc(O)cc(O)c3c2=O)-c2ccc(O)c(O)c2)O[C@@H]([C@@H](O)[C@@H]1O)C(O)=O....
| Schlagworte: | Quercetin 3-O-glucuronide, Quercetin 3-glucuronide |
| Anwendung: | alpha-2C adrenergic receptor inhibitor |
| CAS | 22688-79-5 |
| MW: | 478.36 D |
ab 81,00 €
Apraclonidine (hydrochloride)
Artikelnummer: Cay23904-5
Apraclonidine is an alpha2-adrenergic receptor (alpha2-AR) agonist and structural analog of clonidine (Cay-15949). It binds to alpha2-ARs in calf cortex, rat kidney, and rat spleen with IC50 values of 0.9, 4.3, and 4.2 nM, respectively. Apraclonidine also binds to alpha2-ARs in rat cerebral cortex, pig submandibular...
| Schlagworte: | ALO 2145, AL0 2145, 2,6-dichloro-N1-(4,5-dihydro-1H-imidazol-2-yl)-1,4-benzenediamine, monohydrochloride |
| Anwendung: | alpha2-Adrenergic receptor agonist |
| CAS | 73218-79-8 |
| MW: | 281.6 D |
ab 48,00 €
Anti-ADRA2C
Artikelnummer: CSB-PA000916.100
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
| Schlagworte: | Anti-ADRA2C, Anti-ADRA2L2, Anti-Alpha-2CAR, Anti-Alpha-2C adrenoceptor, Anti-Alpha-2C adrenoreceptor, Anti-Alpha-2C... |
| Anwendung: | ELISA, WB, IHC, IF |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 126,00 €
Anti-ADRA2C
Artikelnummer: CSB-PA041229.100
Host Species: Rabbit. Isotype: IgG. Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by...
| Schlagworte: | Anti-ADRA2C, Anti-ADRA2L2, Anti-Alpha-2CAR, Anti-Alpha-2C adrenoceptor, Anti-Alpha-2C adrenoreceptor, Anti-Alpha-2C... |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
283,00 €
Atipamezole (hydrochloride)
Artikelnummer: Cay9001181-5
Atipamezole is an antagonist of alpha2A-adrenergic receptors (alpha2A-ARs, Ki = 1.86 nM). It is selective for alpha2A-ARs over alpha2B- and alpha1-ARs (Kis = 1,949.83 and 13,300 nM, respectively), as well as over 40 receptors, ion channels, and transporters (IC50s = 540->10,000 nM). Atipamezole (0.04, 0.08, and 1.2...
| Schlagworte: | Antisedan(R), 5-(2-ethyl-2,3-dihydro-1H-inden-2-yl)-1H-imidazole, monohydrochloride |
| Anwendung: | alpha2-adrenergic receptor antagonist |
| CAS | 104075-48-1 |
| MW: | 248.8 D |
ab 99,00 €
Dexmedetomidine (hydrochloride)
Artikelnummer: Cay15581-5
Dexmedetomidine is the (S)-enantiomer of medetomidine, an imidazole compound that binds to alpha2-adrenoceptors (Ki = 1.08 nM) with high affinity and selectivity compared to that of alpha1-adrenoceptors (Ki = 1.8 µM). Dexmedetomidine produces analgesic, sedative, and anxiolytic effects through both presynaptic...
| Schlagworte: | Dex, Precedex, 5-[(1S)-1-(2,3-dimethylphenyl)ethyl]-1H-imidazole, monohydrochloride |
| Anwendung: | alpha2-adrenergic receptor agonist |
| CAS | 145108-58-3 |
| MW: | 236.7 D |
ab 67,00 €
Rauwolscine (hydrochloride)
Artikelnummer: Cay15596-50
Rauwolscine is a natural alkaloid that acts as a selective and reversible alpha2-adrenergic receptor antagonist (Ki = 12 nM). It is a stereoisomer of yohimbine, which potently antagonizes both alpha1- and alpha2-adrenergic receptors. Rauwolscine also acts as a receptor antagonist at the serotonin 5-HT2B receptor (Ki...
| Schlagworte: | Isoyohimbine, NSC 407307, alpha-Yohimbine, (16beta,17alpha,20alpha)-17-hydroxy-yohimban-16-carboxylic acid, methyl ester,... |
| Anwendung: | Selective, reversible alpha2-adrenergic receptor antagonist |
| CAS | 6211-32-1 |
| MW: | 390.9 D |
ab 52,00 €
Guanabenz (hydrochloride)
Artikelnummer: Cay10851-25
Guanabenz is an alpha2-adrenergic receptor agonist (effective concentrations 10-100 nM) with hypotensive effects. It also competes for imidazoline I2-binding sites in brown adipose tissue (Ki = 97 nM).Formal Name: 2-[(2,6-dichlorophenyl)methylene]-hydrazinecarboximidamide, monohydrochloride. CAS Number: 23113-43-1....
| Schlagworte: | Wytensin, 2-[(2,6-dichlorophenyl)methylene]-hydrazinecarboximidamide, monohydrochloride |
| Anwendung: | alpha2-adrenergic receptor agonist |
| CAS | 23113-43-1 |
| MW: | 267.5 D |
ab 62,00 €
Quercetin 3-O-glucuronide
Artikelnummer: Cay21289-1
Quercetin 3-O-glucuronide is a pharmacologically active flavonol glucuronide isolated from H. perforatum (St. John's wort) that inhibits the alpha2c adrenergic receptor (Ki = 4,060 nM in halpha2c preparations).{33869,33870, 33974} Quercetin 3-O-glucuronide (0.6 mg/kg) reduced the time rats spent immobile in the...
| Schlagworte: | Miquelianin, Quercetin 3-O-beta-D-glucuronide,... |
| Anwendung: | alpha-2C adrenergic receptor inhibitor |
| CAS | 22688-79-5 |
| MW: | 478.4 D |
ab 67,00 €
Clonidine (hydrochloride)
Artikelnummer: Cay15949-500
Clonidine is an agonist of alpha2-adrenergic receptors (alpha2-ARs, Kis = 61.66, 69.18, and 134.9 nM for alpha2A-, alpha2B-, and alpha2C-ARs, respectively). It stimulates [35S]GTPgammaS binding to HEK293 cell membranes expressing the human receptors with EC50 values of 26.92, 56.23, and 912.01 nM for alpha2A-,...
| Schlagworte: | ST 155, N-(2,6-dichlorophenyl)-4,5-dihydro-1H-imidazol-2-amine, monohydrochloride |
| Anwendung: | alpha2-adrenergic receptor agonist |
| CAS | 4205-91-8 |
| MW: | 266.6 D |
ab 44,00 €
Medetomidine (hydrochloride)
Artikelnummer: Cay16454-50
Medetomidine is an agonist of alpha2-adrenergic receptors (alpha2-ARs, Ki = 1.08 nM). It is selective for alpha2-ARs over alpha1-ARs (Ki = 1,750 nM). Medetomidine induces sedation in dogs. Formulations containing medetomidine have been used as sedatives in veterinary medicine. This product is also available as an...
| Schlagworte: | Domitor(R), MPV 785, 5-[1-(2,3-dimethylphenyl)ethyl]-1H-imidazole, monohydrochloride |
| Anwendung: | alpha2-adrenergic receptor agonist |
| CAS | 86347-15-1 |
| MW: | 236.7 D |
ab 85,00 €
Yohimbine (hydrochloride)
Artikelnummer: Cay19869-500
Yohimbine is a natural alkaloid that has highest affinity for alpha2-adrenergic receptors (pKis = 8.2, 8.7, and 9.6 for human alpha2A, alpha2B, and alpha2C, respectively), with antagonist activity at these receptors. It less potently antagonizes serotonin 5-HT1 receptors (pKis = 7.3, 6.8, and 7.6 for human HT1A,...
| Schlagworte: | NIH 9689, NSC 19509, Yohimbe, 17alpha-hydroxy-yohimban-16alpha-carboxylic acid, methyl ester, monohydrochloride |
| Anwendung: | Alpha-2A/B/C adrenergic receptor antagonist |
| CAS | 65-19-0 |
| MW: | 390.9 D |
ab 44,00 €