Zu "K04139" wurden 64 Artikel gefunden!
Für die Filterung wurden keine Ergebnisse gefunden!
NEU
Moxonidine
Artikelnummer: Cay25639-10
Moxonidine is an imidazoline 1 (I1) receptor agonist (Ki = 56 nM in a radioligand binding assay). It is also an agonist of the alpha2A-adrenergic receptor (alpha2A-AR, Ki = 150 nM in a radioligand binding assay). It is selective for I1 and alpha2A-AR receptors over alpha1-, alpha2B, and alpha2C-ARs (Kis = >30,000,...
| Schlagworte: | LY326869, 4-chloro-N-(4,5-dihydro-1H-imidazol-2-yl)-6-methoxy-2-methyl-5-pyrimidinamine |
| Anwendung: | Centrally-acting antiadrenergic |
| CAS | 75438-57-2 |
| MW: | 241.7 D |
ab 67,00 €
B-HT 933 dihydrochloride
Artikelnummer: TGM-T21787-1mg
Description: Azepexole dihydrochloride (B-HT 933), a potent and selective alpha 2-adrenoceptor agonist, exhibits affinity for alpha2A-, alpha2B-, and alpha2C-adrenoceptor subtypes with pKis of 8.3, 7.6, and 7.5, respectively [1]. It elicits a concentration-dependent inhibition of peristaltic contractions, evidenced...
| Anwendung: | alpha2-adrenoceptor agonist |
| CAS | 36067-72-8 |
| MW: | 254.16 D |
ab 77,00 €
Methyldopate
Artikelnummer: TGM-T36206-2mg
Description: Methyldopate is an ethyl ester prodrug form of methyldopa , a dopamine decarboxylase inhibitor that has antihypertensive activity in vitro and in vivo., Formulations containing methyldopate have been used in the treatment of hypertension. Target: Others. Smiles: CCOC(=O)[C@@](C)(N)Cc1ccc(O)c(O)c1
| Anwendung: | Dopamine decarboxylase inhibitor prodrug, alpha2-Adrenergic receptor agonist prodrug |
| CAS | 6014-30-8 |
| MW: | 239.27 D |
ab 52,00 €
Piperoxan hydrochloride
Artikelnummer: TGM-T4526-100mg
Description: Piperoxan hydrochloride (Benodaine hydrochloride) is an alpha2 adrenoceptor antagonist. Piperoxan (benodaine) is a drug which was the very first antihistamine to be discovered. Target: Adrenergic Receptor. Smiles: Cl.C(C1COc2ccccc2O1)N1CCCCC1. References: Viemari JC, et al. Nasal trigeminal inputs...
| Schlagworte: | dl-Piperoxan hydrochloride, Benodaine hydrochloride |
| Anwendung: | alpha2-adrenergic receptor (alpha2-AR) antagonist |
| CAS | 135-87-5 |
| MW: | 269.77 D |
ab 41,00 €
Apraclonidine (hydrochloride)
Artikelnummer: Cay23904-1
Apraclonidine is an alpha2-adrenergic receptor (alpha2-AR) agonist and structural analog of clonidine (Cay-15949). It binds to alpha2-ARs in calf cortex, rat kidney, and rat spleen with IC50 values of 0.9, 4.3, and 4.2 nM, respectively. Apraclonidine also binds to alpha2-ARs in rat cerebral cortex, pig submandibular...
| Schlagworte: | ALO 2145, AL0 2145, 2,6-dichloro-N1-(4,5-dihydro-1H-imidazol-2-yl)-1,4-benzenediamine, monohydrochloride |
| Anwendung: | alpha2-Adrenergic receptor agonist |
| CAS | 73218-79-8 |
| MW: | 281.6 D |
ab 47,00 €
2-(1-Piperazinyl)pyrimidine
Artikelnummer: TGM-T1696-1g
Description: 2-(1-Piperazinyl)pyrimidine is used as an anti-anxiety drug. Target: Adrenergic Receptor. Smiles: C1CN(CCN1)C1=NC=CC=N1. References: Rajamani T, Muthu S. Spectrochim Acta A Mol Biomol Spectrosc. 2013 Nov,115:654-66.
| Anwendung: | Alpha2-AR antagonist |
| CAS | 20980-22-7 |
| MW: | 164.21 D |
ab 33,00 €
Anti-ADRA2B
Artikelnummer: CSB-PA585658.100
Host Species: Rabbit. Isotype: IgG. Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by...
| Schlagworte: | Anti-ADRA2B, Anti-ADRA2L1, Anti-Alpha-2BAR, Anti-Alpha-2B adrenoceptor, Anti-Alpha-2B adrenoreceptor, Anti-Alpha-2B... |
| Anwendung: | ELISA, IF |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
275,00 €
Romifidine (hydrochloride)
Artikelnummer: Cay36693-25
Romifidine is an alpha2-adrenergic receptor (alpha2-AR) agonist. Epidural administration of romifidine (50 µg/kg) induces antinociception and sedation in donkeys. It also induces bradycardia in horses when administered at doses ranging from 0.04 to 0.12 mg/kg. Formulations containing romifidine have been used as...
| Schlagworte: | STH 2130, N-(2-bromo-6-fluorophenyl)-4,5-dihydro-1H-imidazol-2-amine, monohydrochloride |
| Anwendung: | Alpha2-AR agonist |
| CAS | 65896-14-2 |
| MW: | 294.6 D |
ab 93,00 €
Dexmedetomidine
Artikelnummer: Cay39544-10
Dexmedetomidine is an agonist of alpha2-adrenergic receptors (alpha2-ARs). It selectively binds to alpha2-ARs over alpha1-ARs (Kis = 0.015 and 5 nM, respectively). In vivo, dexmedetomidine (50 µg/kg) prevents increases in cardiac troponin I (CTnI), a marker of myocardial injury, as well as reduces myocardial...
| Schlagworte: | MPV 1440, 5-[(1S)-1-(2,3-dimethylphenyl)ethyl]-1H-imidazole |
| Anwendung: | Alpha2-AR agonist, sedative-hypnotic |
| CAS | 113775-47-6 |
| MW: | 200.3 D |
ab 53,00 €
Anti-ADRA2B / Alpha-2B Adrenergic Receptor
Artikelnummer: NSJ-F54979-0.08ML
In 1X PBS, pH 7.4, with 0.09% sodium azide. Alpha-2-adrenergic receptors are members of the G protein-coupled receptor superfamily. They include 3 highly homologous subtypes: alpha2A, alpha2B, and alpha2C. These receptors have a critical role in regulating neurotransmitter release from sympathetic nerves and from...
| Schlagworte: | Anti-ADRA2B, Anti-ADRA2L1, Anti-Alpha-2BAR, Anti-Alpha-2B adrenoceptor, Anti-Alpha-2B adrenoreceptor, Anti-Alpha-2B... |
| Anwendung: | WB, IF, FC, IHC (paraffin) |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 326,00 €
Levonordefrin
Artikelnummer: Cay23993-10
Levonordefrin is the (-)-enantiomer of nordefrin, a synthetic derivative of norepinephrine (Cay-16673), that acts as a vasoconstrictor. Levonordefrin (1-5 µg/kg) rapidly increases blood pressure and heart rate in anesthetized dogs and has a more potent effect on blood pressure than the dextronordefrin enantiomer. It...
| Schlagworte: | (-)-3,4-dihydroxy Norephedrine, (-)-alpha-methyl Noradrenaline, Corbadrine,... |
| Anwendung: | Vasoconstrictor, alpha2-Adrenergic receptor agonist |
| CAS | 829-74-3 |
| MW: | 183.2 D |
ab 84,00 €
Medetomidine (hydrochloride)
Artikelnummer: Cay16454-5
Medetomidine is an agonist of alpha2-adrenergic receptors (alpha2-ARs, Ki = 1.08 nM). It is selective for alpha2-ARs over alpha1-ARs (Ki = 1,750 nM). Medetomidine induces sedation in dogs. Formulations containing medetomidine have been used as sedatives in veterinary medicine. This product is also available as an...
| Schlagworte: | Domitor(R), MPV 785, 5-[1-(2,3-dimethylphenyl)ethyl]-1H-imidazole, monohydrochloride |
| Anwendung: | alpha2-adrenergic receptor agonist |
| CAS | 86347-15-1 |
| MW: | 236.7 D |
ab 84,00 €