Zu "K04139" wurden 64 Artikel gefunden!
Für die Filterung wurden keine Ergebnisse gefunden!
Moxonidine
Artikelnummer: Cay25639-10
Moxonidine is an imidazoline 1 (I1) receptor agonist (Ki = 56 nM in a radioligand binding assay). It is also an agonist of the alpha2A-adrenergic receptor (alpha2A-AR, Ki = 150 nM in a radioligand binding assay). It is selective for I1 and alpha2A-AR receptors over alpha1-, alpha2B, and alpha2C-ARs (Kis = >30,000,...
| Schlagworte: | LY326869, 4-chloro-N-(4,5-dihydro-1H-imidazol-2-yl)-6-methoxy-2-methyl-5-pyrimidinamine |
| Anwendung: | Centrally-acting antiadrenergic |
| CAS | 75438-57-2 |
| MW: | 241.7 D |
ab 67,00 €
Lofexidine hydrochloride
Artikelnummer: LKT-L5822.1
It is an alpha2-adrenergic agonist useful in the management of opioid drawer.
| Anwendung: | alpha2-adrenergic agonist |
| CAS | 21498-08-8 |
| MW: | 295,6 D |
ab 160,00 €
Apraclonidine (hydrochloride)
Artikelnummer: Cay23904-1
Apraclonidine is an alpha2-adrenergic receptor (alpha2-AR) agonist and structural analog of clonidine (Cay-15949). It binds to alpha2-ARs in calf cortex, rat kidney, and rat spleen with IC50 values of 0.9, 4.3, and 4.2 nM, respectively. Apraclonidine also binds to alpha2-ARs in rat cerebral cortex, pig submandibular...
| Schlagworte: | ALO 2145, AL0 2145, 2,6-dichloro-N1-(4,5-dihydro-1H-imidazol-2-yl)-1,4-benzenediamine, monohydrochloride |
| Anwendung: | alpha2-Adrenergic receptor agonist |
| CAS | 73218-79-8 |
| MW: | 281.6 D |
ab 48,00 €
2-(1-Piperazinyl)pyrimidine
Artikelnummer: TGM-T1696-1g
Description: 2-(1-Piperazinyl)pyrimidine is used as an anti-anxiety drug. Target: Adrenergic Receptor. Smiles: C1CN(CCN1)C1=NC=CC=N1. References: Rajamani T, Muthu S. Spectrochim Acta A Mol Biomol Spectrosc. 2013 Nov,115:654-66.
| Anwendung: | Alpha2-AR antagonist |
| CAS | 20980-22-7 |
| MW: | 164.21 D |
ab 33,00 €
B-HT 933 dihydrochloride
Artikelnummer: TGM-T21787-1mg
Description: Azepexole dihydrochloride (B-HT 933), a potent and selective alpha 2-adrenoceptor agonist, exhibits affinity for alpha2A-, alpha2B-, and alpha2C-adrenoceptor subtypes with pKis of 8.3, 7.6, and 7.5, respectively [1]. It elicits a concentration-dependent inhibition of peristaltic contractions, evidenced...
| Anwendung: | alpha2-adrenoceptor agonist |
| CAS | 36067-72-8 |
| MW: | 254.16 D |
ab 77,00 €
Methyldopate
Artikelnummer: TGM-T36206-2mg
Description: Methyldopate is an ethyl ester prodrug form of methyldopa , a dopamine decarboxylase inhibitor that has antihypertensive activity in vitro and in vivo., Formulations containing methyldopate have been used in the treatment of hypertension. Target: Others. Smiles: CCOC(=O)[C@@](C)(N)Cc1ccc(O)c(O)c1
| Anwendung: | Dopamine decarboxylase inhibitor prodrug, alpha2-Adrenergic receptor agonist prodrug |
| CAS | 6014-30-8 |
| MW: | 239.27 D |
ab 54,00 €
Piperoxan hydrochloride
Artikelnummer: TGM-T4526-100mg
Description: Piperoxan hydrochloride (Benodaine hydrochloride) is an alpha2 adrenoceptor antagonist. Piperoxan (benodaine) is a drug which was the very first antihistamine to be discovered. Target: Adrenergic Receptor. Smiles: Cl.C(C1COc2ccccc2O1)N1CCCCC1. References: Viemari JC, et al. Nasal trigeminal inputs...
| Schlagworte: | dl-Piperoxan hydrochloride, Benodaine hydrochloride |
| Anwendung: | alpha2-adrenergic receptor (alpha2-AR) antagonist |
| CAS | 135-87-5 |
| MW: | 269.77 D |
ab 37,00 €
Anti-ADRA2B
Artikelnummer: CSB-PA585658.100
Host Species: Rabbit. Isotype: IgG. Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by...
| Schlagworte: | Anti-ADRA2B, Anti-ADRA2L1, Anti-Alpha-2BAR, Anti-Alpha-2B adrenoceptor, Anti-Alpha-2B adrenoreceptor, Anti-Alpha-2B... |
| Anwendung: | ELISA, IF |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
283,00 €
Levonordefrin
Artikelnummer: Cay23993-10
Levonordefrin is the (-)-enantiomer of nordefrin, a synthetic derivative of norepinephrine (Cay-16673), that acts as a vasoconstrictor. Levonordefrin (1-5 µg/kg) rapidly increases blood pressure and heart rate in anesthetized dogs and has a more potent effect on blood pressure than the dextronordefrin enantiomer. It...
| Schlagworte: | (-)-3,4-dihydroxy Norephedrine, (-)-alpha-methyl Noradrenaline, Corbadrine,... |
| Anwendung: | Vasoconstrictor, alpha2-Adrenergic receptor agonist |
| CAS | 829-74-3 |
| MW: | 183.2 D |
ab 85,00 €
Medetomidine (hydrochloride)
Artikelnummer: Cay16454-5
Medetomidine is an agonist of alpha2-adrenergic receptors (alpha2-ARs, Ki = 1.08 nM). It is selective for alpha2-ARs over alpha1-ARs (Ki = 1,750 nM). Medetomidine induces sedation in dogs. Formulations containing medetomidine have been used as sedatives in veterinary medicine. This product is also available as an...
| Schlagworte: | Domitor(R), MPV 785, 5-[1-(2,3-dimethylphenyl)ethyl]-1H-imidazole, monohydrochloride |
| Anwendung: | alpha2-adrenergic receptor agonist |
| CAS | 86347-15-1 |
| MW: | 236.7 D |
ab 85,00 €
Yohimbine (hydrochloride)
Artikelnummer: Cay19869-1
Yohimbine is a natural alkaloid that has highest affinity for alpha2-adrenergic receptors (pKis = 8.2, 8.7, and 9.6 for human alpha2A, alpha2B, and alpha2C, respectively), with antagonist activity at these receptors. It less potently antagonizes serotonin 5-HT1 receptors (pKis = 7.3, 6.8, and 7.6 for human HT1A,...
| Schlagworte: | NIH 9689, NSC 19509, Yohimbe, 17alpha-hydroxy-yohimban-16alpha-carboxylic acid, methyl ester, monohydrochloride |
| Anwendung: | Alpha-2A/B/C adrenergic receptor antagonist |
| CAS | 65-19-0 |
| MW: | 390.9 D |
ab 44,00 €
Fendiline (hydrochloride)
Artikelnummer: Cay17295-5
Fendiline is an alpha2-adrenergic receptor antagonist (Kd = 2.6 µM) and an L-type calcium channel blocker (IC50 = 17 µM) well-known for its coronary vasodilator effects. Fendiline has recently been reported to inhibit K-Ras plasma membrane localization (IC50 = 9.64 µM), which prevents K-Ras signal transduction and...
| Schlagworte: | gamma-phenyl-N-(1-phenylethyl)-benzenepropanamine, monohydrochloride |
| Anwendung: | alpha2-adrenergic receptor antagonist, L-type calcium channel blocker |
| CAS | 13636-18-5 |
| MW: | 351.9 D |
ab 47,00 €