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Zu "K04138" wurden 92 Artikel gefunden!
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Artikelnummer: Cay36693-10
Romifidine is an alpha2-adrenergic receptor (alpha2-AR) agonist. Epidural administration of romifidine (50 µg/kg) induces antinociception and sedation in donkeys. It also induces bradycardia in horses when administered at doses ranging from 0.04 to 0.12 mg/kg. Formulations containing romifidine have been used as...
Schlagworte: | STH 2130, N-(2-bromo-6-fluorophenyl)-4,5-dihydro-1H-imidazol-2-amine, monohydrochloride |
Anwendung: | Alpha2-AR agonist |
CAS | 65896-14-2 |
MW: | 294.6 D |
ab 93,00 €
Artikelnummer: Cay39544-100
Dexmedetomidine is an agonist of alpha2-adrenergic receptors (alpha2-ARs). It selectively binds to alpha2-ARs over alpha1-ARs (Kis = 0.015 and 5 nM, respectively). In vivo, dexmedetomidine (50 µg/kg) prevents increases in cardiac troponin I (CTnI), a marker of myocardial injury, as well as reduces myocardial...
Schlagworte: | MPV 1440, 5-[(1S)-1-(2,3-dimethylphenyl)ethyl]-1H-imidazole |
Anwendung: | Alpha2-AR agonist, sedative-hypnotic |
CAS | 113775-47-6 |
MW: | 200.3 D |
ab 53,00 €
Artikelnummer: Cay16129-500
Chlorpromazine (CPZ) is a typical antipsychotic and an antagonist of dopamine D2, D3, and D4 receptors (Kis = 0.66, 0.84, and 1.2 nM, respectively) as well as the serotonin (5-HT) receptor subtype 5-HT2A (Ki = 1.8 nM). It is also an antagonist of histamine H1, alpha1a-, alpha2b-, and alpha2C-adrenergic, and M3...
Schlagworte: | CPZ, 2-chloro-N,N-dimethyl-10H-phenothiazine-10-propanamine, monohydrochloride |
Anwendung: | 5-HT2-receptor, H1-receptor, dopamine D2-receptor, alpha2-adrenergic receptor antagonist |
CAS | 69-09-0 |
MW: | 355.3 D |
ab 43,00 €
Artikelnummer: Cay39184-1
Xylazine-d6 (CRM) (Cay-39184) is intended for use as an internal standard for the quantification of xylazine (Cay-22641) by GC- or LC-MS. Xylazine is categorized as an anesthetic.. Xylazine has been used as an adulterant in drugs of abuse and misused, leading to non-fatal and fatal intoxications. This product is...
Schlagworte: | N-(2,6-bis(methyl-d3)phenyl)-5,6-dihydro-4H-1,3-thiazin-2-amine |
Anwendung: | Certified reference material, GC-MS, LC-MS internal standard, quantification, anesthetic, adulterant |
CAS | 1228182-53-3 |
MW: | 226.4 D |
340,00 €
Artikelnummer: Cay16454-10
Medetomidine is an agonist of alpha2-adrenergic receptors (alpha2-ARs, Ki = 1.08 nM). It is selective for alpha2-ARs over alpha1-ARs (Ki = 1,750 nM). Medetomidine induces sedation in dogs. Formulations containing medetomidine have been used as sedatives in veterinary medicine. This product is also available as an...
Schlagworte: | Domitor(R), MPV 785, 5-[1-(2,3-dimethylphenyl)ethyl]-1H-imidazole, monohydrochloride |
Anwendung: | alpha2-adrenergic receptor agonist |
CAS | 86347-15-1 |
MW: | 236.7 D |
ab 84,00 €
Artikelnummer: Cay14113-5
Xylazine is an agonist of alpha2-adrenergic receptors (Ki = 194 nM). It is an analog of clonidine, an alpha2-adrenergic receptor agonist used to reduce blood pressure. Xylazine is used for sedation, anesthesia, and analgesia in non-human mammals. This product is also available as an analytical reference standard...
Schlagworte: | N-(2,6-dimethylphenyl)-5,6-dihydro-4H-1,3-thiazin-2-amine |
Anwendung: | alpha2 adrenergic receptor agonist |
CAS | 7361-61-7 |
MW: | 220.3 D |
ab 52,00 €
Artikelnummer: Cay37854-1
Xylazine (CRM) (Cay-37854) is a certified reference material categorized as an anesthetic. It has been used as an adulterant in drugs of abuse and misused, leading to non-fatal and fatal intoxications. This product is intended for use in analytical forensic applications. This product is also available as a general...
Schlagworte: | N-(2,6-dimethylphenyl)-5,6-dihydro-4H-1,3-thiazin-2-amine |
Anwendung: | Certified reference material, anesthetic, alpha2-adrenergic receptor agonist |
CAS | 7361-61-7 |
MW: | 220.3 D |
164,00 €
Artikelnummer: Cay36692-1
Xylazine is an agonist of alpha2-adrenergic receptors (Ki = 194 nM). It is an analog of clonidine, an alpha2-adrenergic receptor agonist used to reduce blood pressure. Xylazine is used for sedation, anesthesia, and analgesia in non-human mammals. This product is also available as an analytical reference standard...
Schlagworte: | BAY-Va 1470, N-(2,6-dimethylphenyl)-5,6-dihydro-4H-1,3-thiazin-2-amine, monohydrochloride |
Anwendung: | Alpha2-adrenergic receptors agonist |
CAS | 23076-35-9 |
MW: | 256.8 D |
ab 35,00 €
Artikelnummer: Cay17295-1
Fendiline is an alpha2-adrenergic receptor antagonist (Kd = 2.6 µM) and an L-type calcium channel blocker (IC50 = 17 µM) well-known for its coronary vasodilator effects. Fendiline has recently been reported to inhibit K-Ras plasma membrane localization (IC50 = 9.64 µM), which prevents K-Ras signal transduction and...
Schlagworte: | gamma-phenyl-N-(1-phenylethyl)-benzenepropanamine, monohydrochloride |
Anwendung: | alpha2-adrenergic receptor antagonist, L-type calcium channel blocker |
CAS | 13636-18-5 |
MW: | 351.9 D |
ab 46,00 €
Artikelnummer: Cay15596-100
Rauwolscine is a natural alkaloid that acts as a selective and reversible alpha2-adrenergic receptor antagonist (Ki = 12 nM). It is a stereoisomer of yohimbine, which potently antagonizes both alpha1- and alpha2-adrenergic receptors. Rauwolscine also acts as a receptor antagonist at the serotonin 5-HT2B receptor (Ki...
Schlagworte: | Isoyohimbine, NSC 407307, alpha-Yohimbine, (16beta,17alpha,20alpha)-17-hydroxy-yohimban-16-carboxylic acid, methyl ester,... |
Anwendung: | Selective, reversible alpha2-adrenergic receptor antagonist |
CAS | 6211-32-1 |
MW: | 390.9 D |
ab 50,00 €
Artikelnummer: Cay16673-500
(-)-Norepinephrine is the endogenous isomer of (±)-norepinephrine (Cay-35580) that acts as a neurotransmitter and hormone and is biosynthesized from dopamine by dopamine beta-hydroxylase. It is an agonist of adrenergic receptors (Ki values are 330, 56, and 740 nM for alpha1, alpha2, and beta1 adrenoceptors,...
Schlagworte: | Arterenol, Levarterenol, L-Noradrenaline, NE, 4-[(1R)-2-amino-1-hydroxyethyl]-1,2-benzenediol... |
Anwendung: | Adrenergic receptor agonist, dopamine beta-hydroxylase metabolite |
CAS | 108341-18-0 |
MW: | 337.3 D |
ab 44,00 €
Artikelnummer: Cay15949-1
Clonidine is an agonist of alpha2-adrenergic receptors (alpha2-ARs, Kis = 61.66, 69.18, and 134.9 nM for alpha2A-, alpha2B-, and alpha2C-ARs, respectively). It stimulates [35S]GTPgammaS binding to HEK293 cell membranes expressing the human receptors with EC50 values of 26.92, 56.23, and 912.01 nM for alpha2A-,...
Schlagworte: | ST 155, N-(2,6-dichlorophenyl)-4,5-dihydro-1H-imidazol-2-amine, monohydrochloride |
Anwendung: | alpha2-adrenergic receptor agonist |
CAS | 4205-91-8 |
MW: | 266.6 D |
ab 43,00 €