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Zu "K04135" wurden 79 Artikel gefunden!
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Artikelnummer: Cay40434-10
(±)-Epinephrine-d3 is intended for use as an internal standard for the quantification of (±)-epinephrine (Cay-21245) by GC- or LC-MS. (±)-Epinephrine is a natural neurotransmitter that is released from the adrenal medulla and activates adrenoceptors (Kis = 15, 735, and 3,970 nM for alpha1A-, beta2-, and...
Schlagworte: | (±)-Adrenaline-d3, DL-Adrenaline-d3, DL-Epinephrine-d3, 4-[1-hydroxy-2-(methyl-d3 amino)ethyl]-1,2-benzenediol |
Anwendung: | GC-MS, LC-MS internal standard, quantification, natural neurotransmitter |
CAS | 1189977-29-4 |
MW: | 186.2 D |
ab 101,00 €
Artikelnummer: ELK-ELK7453.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Rat ADRa1A. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Rat ADRa1A. Next,...
Schlagworte: | Adra1c, Adra1a, Alpha-1A adrenoceptor, Alpha-1A adrenoreceptor, Alpha-1C adrenergic receptor, Alpha-1A adrenergic receptor |
Anwendung: | ELISA |
Spezies-Reaktivität: | rat |
ab 365,00 €
Artikelnummer: ELK-ELK1867.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human ADRa1A. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human ADRa1A....
Schlagworte: | ADRA1C, ADRA1A, Alpha-1A adrenoceptor, Alpha-1A adrenoreceptor, Alpha-adrenergic receptor 1c, Alpha-1C adrenergic... |
Anwendung: | ELISA |
Spezies-Reaktivität: | human |
ab 365,00 €
Artikelnummer: IB-IB31001
This is an all-inclusive cell-based luciferase reporter assay kit targeting the the Human Adrenoreceptor Alpha 1A (ADRA1A). INDIGO's ADRA1A reporter assay utilizes proprietary mammalian cells that have been engineered to provide constitutive expression of the ADRA1A. In addition to ADRA1A Reporter Cells, this kit...
Schlagworte: | ADRA1A, ADRA1C, Alpha-1A adrenoceptor, Alpha-1A adrenoreceptor, Alpha-1A adrenergic receptor, Alpha-adrenergic receptor... |
Anwendung: | Functional activity screening |
Spezies-Reaktivität: | human |
1.448,00 €
Artikelnummer: IB-IB31002
This is an all-inclusive cell-based luciferase reporter assay kit targeting the the Human Adrenoreceptor Alpha 1A (ADRA1A). INDIGO's ADRA1A reporter assay utilizes proprietary mammalian cells that have been engineered to provide constitutive expression of the ADRA1A. In addition to ADRA1A Reporter Cells, this kit...
Schlagworte: | ADRA1A, ADRA1C, Alpha-1A adrenoceptor, Alpha-1A adrenoreceptor, Alpha-1A adrenergic receptor, Alpha-adrenergic receptor... |
Anwendung: | Functional activity screening |
Spezies-Reaktivität: | human |
3.803,00 €
Artikelnummer: Cay15023-50
Prazosin is an antagonist of alpha1-adrenergic receptors (alpha1-ARs). It selectively binds to alpha1-ARs with Ki values of 0.2, 0.25, and 0.32 nM for the human recombinant alpha1A-, alpha1B-, and alpha1D-ARs, respectively, over alpha2-ARs (Kis = 340 and 3.7 nM in alpha2A-AR-expressing HT-29 cells and...
Schlagworte: | CP 12,299-1, NSC 292810, [4-(4-amino-6,7-dimethoxy-2-quinazolinyl)-1-piperazinyl]-2-furanyl-methanone, monohydrochloride |
Anwendung: | Antihypertensive agent, melatonin MT3 receptor antagonist |
CAS | 19237-84-4 |
MW: | 419.9 D |
ab 43,00 €
Artikelnummer: Cay15418-50
Carvedilol is an antagonist of the beta-adrenergic receptor (beta-AR, Kds = 1.78, 0.4, and 5.01 nM for beta1-, beta2-, and beta3-ARs, respectively). It also selectively binds to alpha1- over alpha2-ARs (Kis = 0.81 and 3,400 nM, respectively). Carvedilol reverses increases in heart rate induced by the beta1-AR...
Schlagworte: | BM 14190, 1-(9H-carbazol-4-yloxy)-3-[[2-(2-methoxyphenoxy)ethyl]amino]-2-propanol |
Anwendung: | alpha1 / beta adrenergic receptor antagonist |
CAS | 72956-09-3 |
MW: | 406.5 D |
ab 43,00 €
COVID-19 Forschung
Artikelnummer: Cay17201-50
Ifenprodil is an antagonist of NR1A/NR2B subunit-containing NMDA receptors (IC50 = 340 nM). It is selective for NR1A/NR2B subunit-containing NMDA receptors over those containing NR1A/NR2A or NR1A/NR2C subunits (IC50s = 20 and >100 µM, respectively) but also binds to sigma 1 (sigma1) receptors, emopamil binding...
Schlagworte: | NP-120, alpha-(4-hydroxyphenyl)-beta-methyl-4-(phenylmethyl)-1-piperidineethanol, 2R,3R-dihydroxybutanedioate (2:1) |
Anwendung: | N-methyl-D-aspartate receptor (NMDA) NR2B-selective antagonist, alpha1-adrenergic receptor antagonist |
CAS | 23210-58-4 |
MW: | 400.5 D |
ab 43,00 €
Artikelnummer: Cay18865-5
Tolazoline is an alpha1-adrenergic receptor (alpha1-AR, IC50 = 3,200 nM) and alpha2-AR antagonist (Kis = 112, 1,230, 354, and 173 nM for alpha2A, alpha2B-, alpha2C-, and alpha2D-ARs, respectively). Tolazoline inhibits alpha-AR agonist-induced contractions in isolated human corpus cavernosum smooth muscle (IC50 = 0.1...
Schlagworte: | 4,5-dihydro-2-(phenylmethyl)-1H-imidazole, monohydrochloride |
Anwendung: | alpha1/2-adrenergic receptor antagonist |
CAS | 59-97-2 |
MW: | 196.7 D |
ab 43,00 €
Artikelnummer: Cay21791-5
Cirazoline is an alpha1-adrenergic receptor (alpha1-AR) agonist (Kis = 120, 960, and 660 nM for recombinant alpha1A-, alpha1B-, and alpha1D-ARs, respectively, in CHO cell membranes). It acts as a full agonist at alpha1A- and a partial agonist at alpha1B- and alpha1D-ARs in vitro (EC50s = 70.7, 79.4, and 239.8 nM,...
Schlagworte: | 2-[(2-cyclopropylphenoxy)methyl]-4,5-dihydro-1H-imidazole, monohydrochloride |
Anwendung: | alpha-1A adrenoreceptor agonist |
CAS | 40600-13-3 |
MW: | 252.7 D |
ab 114,00 €
Artikelnummer: Cay13648-10
Alfuzosin is a post-synaptic alpha1-adrenergic receptor antagonist commonly used to improve lower urinary tract symptoms associated with benign prostatic hyperplasia (BPH). It displays high-affinity with non-selectivity for the three known human alpha1 adrenoceptors (pKi = 8.0, 8.0, and 8.5 for alpha1A, alpha1B, and...
Schlagworte: | SL 77499-10, Uroxatral, N-[3-[(4-amino-6,7-dimethoxy-2-quinazolinyl)methylamino]propyl]tetrahydro-2-furancarboxamide,... |
Anwendung: | alpha1-adrenergic receptor antagonist |
CAS | 81403-68-1 |
MW: | 425.9 D |
ab 60,00 €
Artikelnummer: AG-CR1-3627-G001
White powder. Soluble in methanol (50 mg/ml), ethanol or water. alpha1-Adrenergic receptor (alpha-AR) antagonist, Prototypical calcium channel protein inhibitor that blocks the L-type Ca2+ channels in smooth and cardiac muscle cells, Vasodilator known to reduce the renal clearance of digoxin and used to control...
Schlagworte: | NSC135784, NSC272366, NSC657799 |
Anwendung: | alpha1-Adrenergic receptor antagonist |
CAS | 152-11-4 |
MW: | 491,1 D |
ab 33,00 €