Zu "K04131" wurden 92 Artikel gefunden!
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CHRM3 Protein, Human, Recombinant (B2M & His)
Artikelnummer: TGM-TMPH-01716-100ug
Description: The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is Pi turnover. CHRM3 Protein, Human, Recombinant (B2M &...
| Schlagworte: | CHRM3, Muscarinic acetylcholine receptor M3 |
| MW: | 40.7 kD |
ab 193,00 €
Tiotropium bromide
Artikelnummer: TGM-T1179-100mg
Description: Tiotropium bromide (BA679 BR) is a long-acting, 24 hour, anticholinergic bronchodilator used in the management of chronic obstructive pulmonary disease (COPD). Tiotropium is a muscarinic receptor antagonist, on topical application it acts mainly on M3 muscarinic receptors located in the airways to...
| Schlagworte: | BA679 BR, Tiopropium |
| Anwendung: | Muscarinic cholinergic receptor antagonist |
| CAS | 136310-93-5 |
| MW: | 472.42 D |
ab 45,00 €
Zamifenacin fumarate
Artikelnummer: TGM-T13385-100mg
Description: Zamifenacin fumarate (UK-76654 fumarate) is a potent, gut-selective antagonist of the muscarinic M3 receptor. Target: AChR. Smiles: OC(=O)\C=C\C(O)=O.C(Cc1ccc2OCOc2c1)N1CCC[C@H](C1)OC(c1ccccc1)c1ccccc1. References: Houghton LA, et al. Zamifenacin (UK-76, 654) a potent gut M3 selective muscarinic...
| Schlagworte: | UK-76654 fumarate |
| Anwendung: | Muscarinic M3 receptor antagonist |
| CAS | 127308-98-9 |
| MW: | 531.6 D |
ab 34,00 €
D-Panthenol
Artikelnummer: TGM-T1437-1g
Description: D-Panthenol (D-Pantothenyl alcohol) is an alcoholic analogue of D-pantothenic acid and cholinergic agent. D-Panthenol acts as a precursor of coenzyme A necessary for acetylation reactions and is involved in the synthesis of acetylcholine. Although the exact mechanism of the actions of D-Panthenol is...
| Schlagworte: | Dexpanthenol, Ilopan, Pantothenol, D-Pantothenyl alcohol |
| Anwendung: | Targets muscarinic acetylcholine receptor M3 (CHRM3) |
| CAS | 81-13-0 |
| MW: | 205.25 D |
ab 32,00 €
Cevimeline
Artikelnummer: TGM-T21119-25mg
Description: Cevimeline, a parasympathomimetic and muscarinic agonist, affects M1 and M3 receptors. Cevimeline has been shown to treat dry mouth and Sj gren's syndrome. It is also used to reduce Xerostomia symptoms and increase salivary flow in head and neck cancer survivors after radiotherapy. Target: Others....
| Schlagworte: | AF-102B, FKS 508, SNI 2011, HSDB 7286 |
| Anwendung: | Targets muscarinic acetylcholine receptor M3 (CHRM3) |
| CAS | 107233-08-9 |
| MW: | 199.31 D |
2.117,00 €
Navafenterol
Artikelnummer: TGM-T30264-5mg
Description: AZD-8871 can present a novel treatment approach to chronic obstructive pulmonary disease [COPD] and potentially also asthma (in combination with an inhaled corticosteroid [ICS]). Target: Others. Smiles:...
| Schlagworte: | LAS-191351, AZD8871, LAS 191351, LAS191351, AZD-8871, AZD 8871 |
| Anwendung: | Targets muscarinic acetylcholine receptor M3 (CHRM3) |
| CAS | 1435519-06-4 |
| MW: | 742.91 D |
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Navafenterol saccharinate
Artikelnummer: TGM-T30265-25mg
Description: AZD-8871 saccharinate is a dual-acting bronchodilator which may be useful in the treatment of Chronic Obstructive Pulmonary Disease (COPD). Target: Others. Smiles:...
| Schlagworte: | AZD-8871 saccharinate, LAS191351 saccharinate, LAS-191351 saccharinate, AZD8871 saccharinate |
| Anwendung: | Targets muscarinic acetylcholine receptor M3 (CHRM3) |
| CAS | 1648550-37-1 |
| MW: | 926.09 D |
1.491,00 €
Sofpironium bromide
Artikelnummer: TGM-T28827-100mg
Description: Sofpironium bromide (BBI4000) belongs to a class of drugs called anticholinergics, which exert their effect by blocking the action of acetylcholine. Target: AChR, Others. Smiles: [Br-].CCOC(=O)C[N+]1(C)CC[C@H](C1)OC(=O)[C@@](O)(C1CCCC1)c1ccccc1. References: Julia Paik, et al. Sofpironium Bromide: First...
| Schlagworte: | BBI4000, BBI 4000, BBI-4000 |
| Anwendung: | Targets muscarinic acetylcholine receptor M3 (CHRM3) |
| CAS | 1628106-94-4 |
| MW: | 470.4 D |
ab 67,00 €
Hexocyclium metilsulfate
Artikelnummer: TGM-T27539-100mg
Description: Hexocyclium metilsulfate has anti-gastric secretory effects in humans. Target: Others. Smiles: O=S(=O)([O-])OC.OC(C=1C=CC=CC1)(CN2CC[N+](C)(C)CC2)C3CCCCC3. References: BRETTE R, LAMBERT R, HALLACQ A. [Action of urogastrone and hexocyclium methylsulfate on gastric secretion in man]. Arch Mal Appar Dig...
| Schlagworte: | AB803, AB-803, AB 803, Traline |
| Anwendung: | Targets muscarinic acetylcholine receptor M3 (CHRM3) |
| CAS | 115-63-9 |
| MW: | 428.59 D |
ab 1.491,00 €
Darifenacin
Artikelnummer: TGM-T62320-500mg
Description: Darifenacin (UK88525) is an M3 muscarinic receptor antagonist (pKi: 8.9). Target: Others. Smiles: C(C(N)=O)([C@H]1CN(CCC=2C=C3C(=CC2)OCC3)CC1)(C4=CC=CC=C4)C5=CC=CC=C5
| Anwendung: | Targets muscarinic acetylcholine receptor M3 (CHRM3) |
| CAS | 133099-04-4 |
| MW: | 426.55 D |
1.237,00 €
Revefenacin
Artikelnummer: TGM-T7392-100mg
Description: Revefenacin (TD-4208) is a mAChR antagonist has a high affinity on M3 receptor( Ki : 0.18 nM),and potentially useful for the treatment of respiratory disease. Target: AChR. Smiles: CN(CCN1CCC(CC1)OC(=O)Nc1ccccc1-c1ccccc1)C(=O)c1ccc(CN2CCC(CC2)C(N)=O)cc1. References: Pulido-Rios MT, McNamara A, Obedencio...
| Schlagworte: | GSK1160724, TD-4208 |
| Anwendung: | Targets muscarinic acetylcholine receptor M3 (CHRM3) |
| CAS | 864750-70-9 |
| MW: | 597.75 D |
ab 35,00 €
Anti-CHRM3 Recombinant Monoclonal, clone 2D4
Artikelnummer: CSB-RA827961A0HU.100
Isotype: Rabbit IgG. Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Affinity-chromatography. Target Name: CHRM3. Antigen Species: Human
| Schlagworte: | Anti-CHRM3, Anti-Muscarinic acetylcholine receptor M3, Muscarinic acetylcholine receptor M3, CHRM3, CHRM3 Recombinant... |
| Anwendung: | ELISA, WB, IHC, FC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 201,00 €