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Zu "K04130" wurden 94 Artikel gefunden!
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NEU
Artikelnummer: DIM-PME101282.10
Recombinant Human CHRM2 Protein with C-terminal human Fc tag. CHRM2(Met1-Glu22) hFc(Glu99-Ala330), Protein function: The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the...
Schlagworte: | HM2 |
Exprimiert in: | Human cells |
Ursprungsart: | human |
CAS | 12 |
MW: | 28.6 kD |
ab 98,00 €
NEU
Artikelnummer: DIM-FLP100111.10
Discover a breakthrough in membrane protein research and drug development with DIMA Biotech's Synthetic Nanodiscs. Traditional methods struggle with challenges in obtaining water-soluble and bioactive forms of multi-transmembrane proteins. Our innovative polymer-based Nanodisc platform offers a game-changing...
Schlagworte: | CHRM2, Muscarinic acetylcholine receptor M2, HM2, Human CHRM2 full length protein-synthetic nanodisc |
Anwendung: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
Exprimiert in: | Human cells |
Ursprungsart: | human |
MW: | 51.7 kD |
ab 1.260,00 €
NEU
Artikelnummer: CSB-PA006807.100
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
Schlagworte: | Anti-CHRM2, Anti-Muscarinic acetylcholine receptor M2, 7TM receptor antibody, Acetylcholine receptor, muscarinic, 2... |
Anwendung: | ELISA, WB, IF |
Wirt: | Rabbit |
Spezies-Reaktivität: | human, mouse, rat |
ab 106,00 €
NEU
Artikelnummer: CSB-PA096500.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: CHRM2. Antigen Species: Human
Schlagworte: | Anti-CHRM2, Anti-Muscarinic acetylcholine receptor M2, 7TM receptor antibody, Acetylcholine receptor, muscarinic, 2... |
Anwendung: | ELISA, IHC |
Wirt: | Rabbit |
Spezies-Reaktivität: | human, mouse, rat |
ab 163,00 €
Artikelnummer: CSB-EP005382HU1.1
Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 210-387aa. Protein Length: Partial. Tag Info: N-terminal 6xHis-tagged. Target Protein Sequence: SRASKSRIKK DKKEPVANQD PVSPSLVQGR IVKPNNNNMP SSDDGLEHNK IQNGKAPRDP VTENCVQGEE KESSNDSTSV SAVASNMRDD EITQDENTVS TSLGHSKDEN SKQTCIRIGT KTPKSDSCTP TNTTVEVVGS...
Schlagworte: | CHRM2, Muscarinic acetylcholine receptor M2, Recombinant Human Muscarinic acetylcholine receptor M2 (CHRM2), partial |
Anwendung: | Activity not tested |
Exprimiert in: | E.coli |
Ursprungsart: | human |
MW: | 23.4 kD |
ab 283,00 €
Artikelnummer: Cay39825-1
Metixene is an antagonist of muscarinic acetylcholine receptors (mAChRs, Ki = 15 nM for the rat receptor). It also inhibits bovine acetylcholinesterase (AChE) by 43% when used at the concentration 10 µM and butyrylcholinesterase (BChE, IC50 = 1.6 µM for the horse enzyme) in cell-free assays. Metixene reduces the...
Schlagworte: | Methixine, 1-methyl-3-(9H-thioxanthen-9-ylmethyl)-piperidine, monohydrochloride, monohydrate |
Anwendung: | Muscarinic acetylcholine receptor antagonist |
CAS | 7081-40-5 |
MW: | 363.9 D |
ab 34,00 €
Artikelnummer: Cay23609-500
Propantheline is an anticholinergic agent. It inhibits contraction of isolated guinea pig ileum induced by acetylcholine (Cay-23829) and reduces intensity of vagal-stimulated gastric contractions in rats. Propantheline (5 mg/kg, s.c.) increases gastric pH and prevents pyloric ligature-induced gastric ulcer formation...
Schlagworte: | SC-3171, N-methyl-N-(1-methylethyl)-N-[2-[(9H-xanthen-9-ylcarbonyl)oxy]ethyl]-2-propanaminium, monobromide |
Anwendung: | Muscarinic acetylcholine receptor antagonist |
CAS | 50-34-0 |
MW: | 448.4 D |
ab 35,00 €
Artikelnummer: Cay12008-1
Atropine is a naturally occurring tropane alkaloid extracted from plants of the family Solanaceae including deadly nightshade (A. belladonna). It is a non-selective, competitive antagonist of the muscarinic acetylcholine receptor types M1, M2, M3, M4, and M5 (pKBs range from 8.9-9.8). Atropine increases firing of...
Schlagworte: | DL-Hyoscyamine, Tropine tropate, alpha-(hydroxymethyl)-(3-endo)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester-benzeneacetic acid |
Anwendung: | Muscarinic acetylcholine receptor antagonist |
CAS | 51-55-8 |
MW: | 289.4 D |
ab 34,00 €
Artikelnummer: Cay14487-500
(+)-Pilocarpine is a muscarinic acetylcholine receptor agonist that binds to human hippocampal, pons, and submandibular gland membranes, which are endogenously enriched in the M1, M2, and M3 receptor subtypes, respectively (apparent Kis = 6, 8.2, and 6.9 µM, respectively). It induces salivary secretion in rats when...
Schlagworte: | NSC 5746, (3S,4R)-3-ethyldihydro-4-[(1-methyl-1H-imidazol-5-yl)methyl]-2(3H)-furanone, monohydrochloride |
Anwendung: | Muscarinic acetylcholine receptor agonist |
CAS | 54-71-7 |
MW: | 244.7 D |
ab 50,00 €
Artikelnummer: Cay20847-50
Oxotremorine M is a non-selective muscarinic (M) acetylcholine receptor agonist that induces phosphoinositide hydrolysis in mouse ileum isolated from wild-type, M2, M3, and M2/M3 knockout mice (EC50s = 0.36, 0.52, 1.62, and 1.48 µM, respectively). It also increases M4-induced inhibition of calcium currents in...
Schlagworte: | N,N,N-trimethyl-4-(2-oxo-1-pyrrolidinyl)-2-butyn-1-aminium, monoiodide |
Anwendung: | Muscarinic receptor agonist |
CAS | 3854-04-4 |
MW: | 322.2 D |
ab 97,00 €
Artikelnummer: Cay23830-1
Bethanechol is an agonist of muscarinic acetylcholine receptors with IC50 values of 1,837, 25, 631, 317, and 393 µM for M1-5, respectively, in a radioligand binding assay using CHO cells expressing the human receptors. It inhibits M2-mediated increases in cyclic AMP induced by isoproterenol (Cay-15592) in isolated...
Schlagworte: | (±)-Bethanechol, Carbamyl-beta-methylcholine chloride, NSC 30783, 2-[(aminocarbonyl)oxy]-N,N,N-trimethyl-1-propanaminium,... |
Anwendung: | Muscarinic acetylcholine receptor agonist |
CAS | 590-63-6 |
MW: | 196.7 D |
ab 50,00 €
Artikelnummer: Cay23825-1
Oxybutynin is an antagonist of muscarinic acetylcholine receptors (Kis = 5, 14.5, 3.7, 5.3, and 40 nM for human recombinant M1-5, respectively). It inhibits intracellular calcium mobilization induced by carbamoylcholine (carbachol, Cay-14486) in bladder smooth muscle and submandibular gland cells isolated from...
Schlagworte: | MJ4309-1, 4-(diethylamino)-2-butyn-1-yl ester alpha-cyclohexyl-alpha-hydroxy-benzeneacetic acid, monohydrochloride |
Anwendung: | Muscarinic cholinergic receptor antagonist |
CAS | 1508-65-2 |
MW: | 394 D |
ab 98,00 €