Zu "K04129" wurden 127 Artikel gefunden!
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Scopolamine (hydrobromide)
Artikelnummer: Cay14108-1
Scopolamine is a tropane alkaloid that can be found in many plants of the Solanaceae (nightshade) family. It is a muscarinic receptor antagonist that can be used to induce memory impairment in animals. Scopolamine prevents motion sickness, nausea, and vomiting in animals.Formal Name:...
| Schlagworte: | Hyoscine, (1alpha,2beta,4beta,5alpha,7beta)-9-methyl-3-oxa-9-azatricyclo[3.3.1.02,4]non-7-yl ester... |
| Anwendung: | Analytical reference standard, tropane alkaloid, muscarinic receptor antagonist, antiemetic |
| CAS | 114-49-8 |
| MW: | 384.3 D |
ab 111,00 €
Cyclobenzaprine (hydrochloride)
Artikelnummer: Cay15885-1
Cyclobenzaprine is a skeletal muscle relaxant that also has sedative properties. It has been shown to antagonize muscarinic receptors (Kis = 25, 60, and 6 nM for M1, M2, and M3, respectively), serotonin 5-HT2 receptors (Kis = 56 and 330 nM for 5-HT2C and 5-HT2B, respectively), and histamine H1 receptor (IC50 = 20...
| Schlagworte: | MK-130, 3-(5H-dibenzo[a,d]cyclohepten-5-ylidene)-N,N-dimethyl-1-propanamine, monohydrochloride |
| Anwendung: | Analytical reference material, skeletal muscle relaxant |
| CAS | 6202-23-9 |
| MW: | 311.9 D |
ab 35,00 €
Aceclidine
Artikelnummer: TGM-T19870-100mg
Description: Aceclidine (1-azabicyclo[2.2.2]octan-3-yl acetate) is a modulator of M3 mAChR and can be used in studies about treating glaucoma by reducing intraocular pressure. Target: AChR. Smiles: CC(=O)OC1CN2CCC1CC2. References: Ehlert FJ, Griffin MT, Glidden PF. The interaction of the enantiomers of aceclidine...
| Schlagworte: | Quinuclidin-3-yl acetate, NSC 657843, 1-azabicyclo[2.2.2]octan-3-yl acetate, 3-Acetoxyquinuclidine, NSC657843,... |
| Anwendung: | Targets muscarinic acetylcholine receptor M1 (CHRM1) |
| CAS | 827-61-2 |
| MW: | 169.22 D |
ab 37,00 €
TBPB
Artikelnummer: TGM-T1760-100mg
Description: TBPB, an allosteric M1 mAChR agonist, is an [iso]propyl (2-{4-methoxy-3-[3-(4-methylpiperidin-1-yl)propoxy]phenyl}ethyl)carbamate exhibiting a molar mass of 430.6 g/mol. Target: AChR. Smiles: Cc1ccccc1CN1CCC(CC1)N1CCC(CC1)n1c2ccccc2[nH]c1=O. References: Jones CK, et al. J Neurosci. 2008 Oct...
| Anwendung: | Muscarinic acetylcholine receptor M1 agonist |
| CAS | 634616-95-8 |
| MW: | 404.55 D |
ab 40,00 €
Dicyclomine
Artikelnummer: TGM-T60751-100mg
Description: Dicyclomine (Dicycloverine) is a potent, orally active antagonist of muscarinic cholinergic receptors, specifically M1 and M2 subtypes, with Ki values of 5.1 nM and 54.6 nM in brush-border and basal plasma membranes, respectively [1] [2]. As an antispasmodic agent, it relieves smooth muscle spasm of the...
| Anwendung: | Targets muscarinic acetylcholine receptor M1 (CHRM1) |
| CAS | 77-19-0 |
| MW: | 309.49 D |
ab 1.520,00 €
Xanomeline oxalate
Artikelnummer: TGM-T13353-100mg
Description: Xanomeline oxalate (LY246708 oxalate), a potent and selective muscarinic receptor agonist (SMRA), effectively stimulates in vivo phosphoinositide hydrolysis. It is a valuable compound for Alzheimer's disease research. Target: AChR. Smiles: OC(=O)C(O)=O.CCCCCCOc1nsnc1C1=CCCN(C)C1. References: F P...
| Schlagworte: | LY246708 oxalate |
| Anwendung: | Muscarinic acetylcholine receptors agonist |
| CAS | 141064-23-5 |
| MW: | 371.45 D |
ab 33,00 €
Oxotremorine M iodide
Artikelnummer: TGM-T12339-10mg
Description: Oxotremorine M iodide (Oxotremorine methiodide) is an agonist of mAChR and potentiates NMDA receptors. Target: AChR. Smiles: [I-].C[N+](C)(C)CC#CCN1CCCC1=O. References: Tran JA, et al. Differential coupling of muscarinic M1, M2, and M3 receptors to phosphoinositide hydrolysis in urinary bladder and...
| Schlagworte: | Oxotremorine methiodide |
| Anwendung: | Muscarinic receptor agonist |
| CAS | 3854-04-4 |
| MW: | 322.19 D |
ab 43,00 €
Alvameline maleate
Artikelnummer: TGM-T14197L-100mg
Description: Alvameline maleate is used as a Partial M1 Agonist and M2/M3 Antagonist. Target: Others. Smiles: C(=C\C(O)=O)\C(O)=O.C(C)N1N=C(N=N1)C=2CN(C)CCC2. References: Tapia E, Sánchez-Lozada LG, García-Niño WR, García E, Cerecedo A, García-Arroyo FE, Osorio H, Arellano A, Cristóbal-García M, Loredo ML,...
| Schlagworte: | Lu 25-109-M |
| Anwendung: | Targets muscarinic acetylcholine receptor M1 (CHRM1) |
| CAS | 219581-36-9 |
| MW: | 309.32 D |
ab 1.520,00 €
Dicyclomine hydrochloride
Artikelnummer: TGM-T1460-1mL
Description: Dicyclomine hydrochloride is a muscarinic antagonist used as an antispasmodic and in urinary incontinence. Target: AChR. Smiles: Cl.CCN(CC)CCOC(=O)C1(CCCCC1)C1CCCCC1. References: Jin CH, et al. J Neurosci Res. 2009 Dec,87(16):3658-70.
| Anwendung: | Targets muscarinic acetylcholine receptor M1 (CHRM1) |
| CAS | 67-92-5 |
| MW: | 345.95 D |
ab 31,00 €
MK-7622
Artikelnummer: TGM-T15942-10mg
Description: MK-7622 (M1 receptor modulator) is a positive allosteric modulator of the muscarinic M1 receptor. Target: AChR. Smiles: Cc1ccc(Cc2cc3c(ncn([C@H]4CCCC[C@@H]4O)c3=O)c3ccccc23)cn1. References: Kuduk Scott D, et al. Dihydrobenzoquinazolinone M1 receptor positive allosteric modulators. From PCT Int. Appl....
| Schlagworte: | M1 receptor modulator |
| Anwendung: | Muscarinic acetylcholine receptor M1 positive allosteric modulator |
| CAS | 1227923-29-6 |
| MW: | 399.48 D |
ab 45,00 €
Oxyphencyclimine Hydrochloride
Artikelnummer: TGM-T2138-1mg
Description: Oxyphencyclimine Hydrochloride (Ulcociclinina) is a synthetic tertiary amine and antimuscarinic agent with antispasmodic and antisecretory activities. Target: AChR. Smiles: Cl.CN1CCCN=C1COC(=O)C(O)(C1CCCCC1)c1ccccc1. References: Waelbroeck M, et al. Eur J Pharmacol. 1992 Sep 1,227(1):33-42.
| Schlagworte: | Spazamin, Daricon, Ulcociclinina |
| Anwendung: | Targets muscarinic acetylcholine receptor M1 (CHRM1) |
| CAS | 125-52-0 |
| MW: | 380.91 D |
ab 48,00 €
Oxyphencyclimine
Artikelnummer: TGM-T2138L-25mg
Description: Oxyphencyclimine is a muscarinic receptor antagonist (MRA) anticholinergic drug used to treat peptic ulcers. Target: Others. Smiles: C(C(OCC=1N(C)CCCN1)=O)(O)(C2CCCCC2)C3=CC=CC=C3. References: Klaphajone J, Kitisomprayoonkul W, Sriplakit S. Botulinum toxin type A injections for treating neurogenic...
| Schlagworte: | Caridan, Naridan, Oxiphencycliminum, Manir, Zamanil, Antulcus |
| Anwendung: | Targets muscarinic acetylcholine receptor M1 (CHRM1) |
| CAS | 125-53-1 |
| MW: | 344.45 D |
ab 1.520,00 €