Zu "K04129" wurden 118 Artikel gefunden!
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Scopolamine (hydrobromide)
Artikelnummer: Cay14108-1
Scopolamine is a tropane alkaloid that can be found in many plants of the Solanaceae (nightshade) family. It is a muscarinic receptor antagonist that can be used to induce memory impairment in animals. Scopolamine prevents motion sickness, nausea, and vomiting in animals.Formal Name:...
| Schlagworte: | Hyoscine, (1alpha,2beta,4beta,5alpha,7beta)-9-methyl-3-oxa-9-azatricyclo[3.3.1.02,4]non-7-yl ester... |
| Anwendung: | Analytical reference standard, tropane alkaloid, muscarinic receptor antagonist, antiemetic |
| CAS | 114-49-8 |
| MW: | 384.3 D |
ab 109,00 €
Cyclobenzaprine (hydrochloride)
Artikelnummer: Cay15885-1
Cyclobenzaprine is a skeletal muscle relaxant that also has sedative properties. It has been shown to antagonize muscarinic receptors (Kis = 25, 60, and 6 nM for M1, M2, and M3, respectively), serotonin 5-HT2 receptors (Kis = 56 and 330 nM for 5-HT2C and 5-HT2B, respectively), and histamine H1 receptor (IC50 = 20...
| Schlagworte: | MK-130, 3-(5H-dibenzo[a,d]cyclohepten-5-ylidene)-N,N-dimethyl-1-propanamine, monohydrochloride |
| Anwendung: | Analytical reference material, skeletal muscle relaxant |
| CAS | 6202-23-9 |
| MW: | 311.9 D |
ab 34,00 €
Oxyphencyclimine Hydrochloride
Artikelnummer: TGM-T2138-1mg
Description: Oxyphencyclimine Hydrochloride (Ulcociclinina) is a synthetic tertiary amine and antimuscarinic agent with antispasmodic and antisecretory activities. Target: AChR. Smiles: Cl.CN1CCCN=C1COC(=O)C(O)(C1CCCCC1)c1ccccc1. References: Waelbroeck M, et al. Eur J Pharmacol. 1992 Sep 1,227(1):33-42.
| Schlagworte: | Spazamin, Daricon, Ulcociclinina |
| Anwendung: | Targets muscarinic acetylcholine receptor M1 (CHRM1) |
| CAS | 125-52-0 |
| MW: | 380.91 D |
ab 48,00 €
Oxyphencyclimine
Artikelnummer: TGM-T2138L-25mg
Description: Oxyphencyclimine is a muscarinic receptor antagonist (MRA) anticholinergic drug used to treat peptic ulcers. Target: Others. Smiles: C(C(OCC=1N(C)CCCN1)=O)(O)(C2CCCCC2)C3=CC=CC=C3. References: Klaphajone J, Kitisomprayoonkul W, Sriplakit S. Botulinum toxin type A injections for treating neurogenic...
| Schlagworte: | Caridan, Naridan, Oxiphencycliminum, Manir, Zamanil, Antulcus |
| Anwendung: | Targets muscarinic acetylcholine receptor M1 (CHRM1) |
| CAS | 125-53-1 |
| MW: | 344.45 D |
ab 1.491,00 €
Cevimeline hydrochloride
Artikelnummer: TGM-T20131-2mg
Description: Cevimeline HCl is an agonist of cholinergic that binds to muscarinic receptors. Muscarinic agonists in sufficient dosage can enhance the secretion of exocrine glands, such as salivary and sweat glands. Target: Others. Smiles: Cl.C[C@@H]1O[C@@]2(CS1)CN1CCC2CC1. References: Malallah OS, Garcia CMA,...
| Schlagworte: | Evoxac, Cevimeline HCl |
| Anwendung: | Muscarinic receptor agonist |
| CAS | 107220-28-0 |
| MW: | 235.77 D |
58,00 €
Tridihexethyl chloride
Artikelnummer: TGM-T34936-100mg
Description: Tridihexethyl is an anticholinergic, antimuscarinic, and antispasmolytic drug, which can be used to treat acquired nystagmus or peptic ulcer disease. Target: Others. Smiles: [Cl-].OC(C=1C=CC=CC1)(CC[N+](CC)(CC)CC)C2CCCCC2. References: Leigh RJ, Burnstine TH, Ruff RL, Kasmer RJ. Effect of anticholinergic...
| Schlagworte: | Propethonum, Pathilon, Tridihexethyl |
| Anwendung: | Targets muscarinic acetylcholine receptor M1 (CHRM1) |
| CAS | 4310-35-4 |
| MW: | 353.97 D |
ab 967,00 €
Sabcomeline hydrochloride
Artikelnummer: TGM-T28654-2mg
Description: Sabcomeline is a selective M1 receptor partial agonist. Target: Others. Smiles: Cl.CO\N=C(/C#N)[C@H]1CN2CCC1CC2. References: McArthur RA, Gray J, Schreiber R. Cognitive effects of muscarinic M1 functional agonists in non-human primates and clinical trials. Curr Opin Investig Drugs. 2010...
| Schlagworte: | BCI224, BCI-224, BRL-55473, CEB-2424, Sabcomeline HCl, SB-202026A |
| Anwendung: | Targets muscarinic acetylcholine receptor M1 (CHRM1) |
| CAS | 159912-58-0 |
| MW: | 229.71 D |
478,00 €
VU0357017 hydrochloride
Artikelnummer: TGM-T3619-100mg
Description: VU0357017 hydrochloride (ML071 hydrochloride) is highly selective M1 agonists act at an allosteric site to activate the receptor (EC50: 477 ± 172 nM, Pec50: 6.37 ± 0.15). Target: AChR. Smiles: Cl.CCOC(=O)N1CCC(CC1)NCCNC(=O)c1ccccc1C. References: Digby GJ, et al. ACS Chem Neurosci. 2012 Dec...
| Schlagworte: | ML071 hydrochloride, VU 0357017 hydrochloride, CID-25010775 |
| Anwendung: | M1 muscarinic acetylcholine allosteric agonist |
| CAS | 1135242-13-5 |
| MW: | 369.89 D |
ab 35,00 €
Sceptrin
Artikelnummer: TGM-T34564-100mg
Description: Sceptrin is a pyrrole-imidazole alkaloid that is naturally produced by various marine sponges. Target: Others. Smiles: O=C(C1=CC(Br)=CN1)NC[C@H]2[C@H](C3=CN=C(N3)N)[C@@H](C4=CN=C(N4)N)[C@@H]2CNC(C5=CC(Br)=CN5)=O.Cl.Cl. References: Ma Z, Wang X, Wang X, Rodriguez RA, Moore CE, Gao S, Tan X, Ma Y,...
| Anwendung: | Antibiotic, competitive mAChR inhibitor |
| CAS | 79703-25-6 |
| MW: | 693.22 D |
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Oxyphenonium bromide
Artikelnummer: TGM-T33846-100mg
Description: Oxyphenonium bromide (Oxyfenon) shows anticholinergic activity and can be used for research on the treatment of gastric and duodenal ulcers and for the relief of visceral spasms. Target: Others. Smiles: [Br-].CC[N+](C)(CC)CCOC(=O)C(O)(C1CCCCC1)c1ccccc1. References: El-Gindy A, Emara S, Shaaban H....
| Schlagworte: | Oxyfenon, Atrenyl, Oxyphenon, 50-10-2, Spasmophen, Oxifenon |
| Anwendung: | Targets muscarinic acetylcholine receptor M1 (CHRM1) |
| CAS | 50-10-2 |
| MW: | 428.404 D |
ab 39,00 €
Xanomeline
Artikelnummer: TGM-T36640-100mg
Description: Xanomeline (LY-246708) is a functionally selective M1/M4 activator used in the study of neurological disorders such as schizophrenia and has shown promising treatment in preclinical trials. Xanomeline is well absorbed orally, crosses the blood-brain barrier and undergoes extensive liver metabolism with...
| Schlagworte: | LY-246708 |
| Anwendung: | Targets muscarinic acetylcholine receptor M1 (CHRM1) |
| CAS | 131986-45-3 |
| MW: | 281.42 D |
ab 31,00 €
Xanomeline tartrate
Artikelnummer: TGM-T39010-2mg
Description: Xanomeline tartrate (LY 246708 tartrate) is an M1 and M4 mAChR agonist with antipsychotic-like activity that improves cognition and can be used in studies of schizophrenia and Alzheimer's disease. Target: Others. Smiles: O[C@@H]([C@H](O)C(O)=O)C(O)=O.CCCCCCOc1nsnc1C1=CCCN(C)C1. References: Kreir M, et...
| Schlagworte: | LY246708 tartrate, LY 246708 tartrate, LY-246708 tartrate |
| Anwendung: | Targets muscarinic acetylcholine receptor M1 (CHRM1) |
| CAS | 152854-19-8 |
| MW: | 431.5 D |
ab 31,00 €