Zu "K04097" wurden 37 Artikel gefunden!
Für die Filterung wurden keine Ergebnisse gefunden!
Anti-HPGDS
Artikelnummer: ABS-KC-2583.100
Protein function: Bifunctional enzyme which catalyzes both the conversion of PGH2 to PGD2, a prostaglandin involved in smooth muscle contraction/relaxation and a potent inhibitor of platelet aggregation, and the conjugation of glutathione with a wide range of aryl halides and organic isothiocyanates. Also exhibits...
| Schlagworte: | Anti-Hematopoietic prostaglandin D synthase, Anti-H-PGDS, Anti-GST class-sigma, Anti-Glutathione S-transferase,... |
| Anwendung: | IHC |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
ab 206,00 €
F092
Artikelnummer: TGM-T69730-100mg
Description: F092 is a potent inhibitor of hematopoietic prostaglandin D synthetase (H-PGDS), which can be used to study allergic inflammation and vascular-related diseases. Target: PGE Synthase. Smiles: O=C(NC1=CC=C(C=C1)N2C(=O)CCC2)C=3C=NC(=NC3)C4=NC=CC=C4. References: Takaya D, et al. Characterization of crystal...
| Anwendung: | Hematopoietic prostaglandin D synthase (H-PGDS) inhibitor |
| CAS | 2250261-59-5 |
| MW: | 359.38 D |
ab 57,00 €
HPGDS inhibitor 2
Artikelnummer: TGM-T7948-100mg
Description: HPGDS inhibitor 2 (GSK-2894631A) is a potent, selective hematopoietic prostaglandin D synthase (h-pgds) inhibitor, IC50 = 9.9 nm. Target: PGE Synthase. Smiles: CC(C)(O)[C@H]1CC[C@@H](CC1)NC(=O)c1cnc2cc(OC(F)F)ccc2c1. References: Rc A , Dnd A , Yd A , et al. The exploration of aza-quinolines as...
| Schlagworte: | GSK-2894631A |
| Anwendung: | HPGDS (Hematopoietic prostaglandin D synthase) inhibitor |
| CAS | 2101626-26-8 |
| MW: | 378.41 D |
ab 88,00 €
PGDS Protein, Human, Recombinant
Artikelnummer: TGM-TMPJ-00690-10ug
Description: Hematopoietic Prostaglandin D Synthase (HPGDS) belongs to the GST superfamily and Sigma family. HPGDS contains one GST C-terminal domain and one GST N-terminal domain. HPGDS is highly expressed in adipose tissue, macrophages, and placenta, and it exists in the form of homodimer in living body. HPGDS is...
| Schlagworte: | Glutathione S-Transferase, PGDS, Glutathione-Requiring Prostaglandin D Synthase, H-PGDS, GST Class-Sigma, PTGDS2, GSTS,... |
| MW: | 26 kD |
ab 181,00 €
HPGDS/PGD2 Protein, Human, Recombinant (His)
Artikelnummer: TGM-TMPY-04077-50ug
Description: HPGDS/PGD2 Protein, Human, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 24.2 kDa and the accession number is O60760.
| Schlagworte: | hematopoietic prostaglandin D synthase, GSTS1, PGDS, PGD2, GSTS1-1, GSTS |
| MW: | 24.2 kD |
599,00 €
HPGDS inhibitor 1
Artikelnummer: TGM-T1804-100mg
Description: HPGDS inhibitor 1 is a novel and selective inhibitor for Hematopoietic Prostaglandin D Synthase (HPGDS) with an IC50 Value of 0.7 nM. Target: PGE Synthase. Smiles: Fc1cccc(c1)-c1ccc(cn1)C(=O)NC1CCN(CC(F)(F)F)CC1. References: Chris P. Carron, et al. ACS Med. Chem. Lett., 2010, 1 (2), pp 59-63
| Schlagworte: | HPGDS-inhibitor-1 |
| Anwendung: | HPGDS (Hematopoietic prostaglandin D synthase) inhibitor |
| CAS | 1033836-12-2 |
| MW: | 381.37 D |
ab 45,00 €
HPGDS inhibitor 3
Artikelnummer: TGM-T61250-100mg
Description: HPGDS inhibitor 3 is a powerful oral compound that selectively inhibits the hematopoietic prostaglandin D synthase (H-PGDS). With an IC50 value of 9.4 nM and EC50 of 42 nM, it demonstrates high potency in peripherally restricting H-PGDS. Moreover, HPGDS inhibitor 3 exhibits excellent selectivity with no...
| Anwendung: | HPGDS (Hematopoietic prostaglandin D synthase) inhibitor |
| CAS | 2255311-93-2 |
| MW: | 353.46 D |
ab 2.142,00 €
TFC-007
Artikelnummer: TGM-T24870-10mg
Description: TFC-007 is an inhibitor of hematopoietic prostaglandin D synthase. Target: Others. Smiles: C(=O)(C1CCN(CC1)C2=CC=C(NC(=O)C=3C=NC(OC4=CC=CC=C4)=NC3)C=C2)N5CCOCC5. References: Nabe T, Kuriyama Y, Mizutani N, Shibayama S, Hiromoto A, Fujii M, Tanaka K, Kohno S. Inhibition of hematopoietic prostaglandin D...
| Schlagworte: | TFC007 |
| Anwendung: | H-PGDS inhibitor |
| CAS | 927878-49-7 |
| MW: | 487.55 D |
ab 128,00 €
TAS 205
Artikelnummer: TGM-T38350-1mg
Description: TAS 205 is an inhibitor of hematopoietic prostaglandin D synthase (H-PGDS, IC50= 55.8 nM).1It is selective for H-PGDS over lipocalin-type PGDS (L-PGDS) at 100 µM, as well as over enzyme and receptor panels at 10 µM. TAS 205 inhibits production of prostaglandin D2induced by A23187 in KU812 human and...
| Anwendung: | H-PGDS inhibitor |
| CAS | 1584160-52-0 |
| MW: | 526.638 D |
ab 214,00 €
PROTAC(H-PGDS)-7
Artikelnummer: TGM-T41267-1mg
Description: PROTAC(H-PGDS)-7 is a selective and potent small molecule hematopoietic prostaglandin D synthase (H-PGDS) PROTAC degradation agent that exhibits degradation activity in KU812 cells with a DC50 of 17.3 pM. It effectively inhibits prostaglandin D2 (PGD2) and is a candidate compound for the treatment of...
| Anwendung: | PROTAC, H-PGDS degradation |
| CAS | 2761281-50-7 |
| MW: | 742.78 D |
ab 492,00 €
Anti-Prostaglandin D Synthase (hematopoietic-type, human)...
Artikelnummer: Cay10004345-1
Prostaglandin D synthase (PGDS) is a glutathione-dependent enzyme and member of the sigma class of glutathione-S-transferases (GSTs) that catalyzes the conversion of PGH2 (Cay-17020) to PGD2 (Cay-12010), an eicosanoid that has numerous biological functions, including vasorelaxation, recruitment of inflammatory...
| Schlagworte: | H-PGD Synthase, H-PGDS |
| Anwendung: | IHC, WB |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human, mouse |
431,00 €
TFC 007
Artikelnummer: Cay17971-5
TFC 007 is an inhibitor of hematopoietic prostaglandin D synthase (H-PGDS, IC50 = 0.083 µM). It is selective for H-PGDS over lipocalin PGDS (L-PGDS) and microsomal PGE2 synthase (mPGES) at 100 µM. It is also selective for H-PGDS over COX-1, COX-2, 5-lipoxygenase (5-LO), leukotriene C4 (LTC4) synthase, and...
| Schlagworte: | N-[4-[4-(4-morpholinylcarbonyl)-1-piperidinyl]phenyl]-2-phenoxy-5-pyrimidinecarboxamide |
| Anwendung: | H-PGDS inhibitor |
| CAS | 927878-49-7 |
| MW: | 487.6 D |
ab 52,00 €