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Zu "K03853" wurden 29 Artikel gefunden!
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Artikelnummer: ELK-ELK4208.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human CAPN2. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human CAPN2. Next,...
Schlagworte: | CAPN2, CANP 2, CANPL2, M-calpain, EC=3.4.22.53, Calpain M-type, Millimolar-calpain, Calpain-2 large subunit, Calpain-2... |
Anwendung: | ELISA |
Spezies-Reaktivität: | human |
ab 365,00 €
Artikelnummer: Cay14283-5
The calpains are a family of calcium-dependent cysteine proteases that catalyze limited proteolysis of substrates. Calpain Inhibitor III is a cell permeable, selective inhibitor of µ-calpain (calpain-1) and m-calpain (calpain-2). Calpain Inhibitor III crosses the blood-brain barrier to inhibit brain cysteine...
Schlagworte: | MDL 28170, N-[(1S)-1-[[(1-formyl-2-phenylethyl)amino]carbonyl]-2-methylpropyl]-carbamic acid, phenylmethyl ester |
Anwendung: | Calpain 1 and 2 inhibitor |
CAS | 88191-84-8 |
MW: | 382.5 D |
ab 43,00 €
Artikelnummer: Cay15994-10
Calpain inhibitor II is a cell permeable, peptide aldehyde inhibitor of calpain I (Ki = 120 nM), calpain II (Ki = 230 nM), cathepsin B (Ki = 100 nM), and cathepsin L (Ki = 0.6 nM). It has been used to demonstrate the involvement of ubiquitin-proteasome protein degradation in various biological systems.Formal Name:...
Schlagworte: | Ac-Leu-Leu-Met-H, ALLM, N-acetyl-L-leucyl-N-[(1S)-1-formyl-3-(methylthio)propyl]-L-leucinamide |
Anwendung: | Calpain I/II & cathepsin B inhibitor |
CAS | 110115-07-6 |
MW: | 401.6 D |
ab 43,00 €
Artikelnummer: AG-CR1-0066-M005
Cell permeable and selective calpain inhibitor. Interacts with calcium-binding domain of calpain, Neuroprotective, Ca2+permeable AMPA receptor inhibitor, Apoptosis inhibitor .
Schlagworte: | 3-(4-Iodophenyl)-2-mercapto-(Z)-2-propenoic acid |
Anwendung: | Calpain inhibitor |
MW: | 306,1 D |
ab 83,00 €
Artikelnummer: Cay10008120-25
The calpains are a family of calcium-dependent cysteine proteases, with calpain I (µ-calpain) requiring micromolar calcium and calpain II (m-calpain) requiring millimolar calcium. Suc-Leu-Tyr-AMC is a fluorescent substrate for calpain I and II and papain (another cysteine protease) that is used for measuring the...
Schlagworte: | Suc-LY-AMC, N-(3-carboxy-1-oxopropyl)-L-leucyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-L-tyrosinamide |
Anwendung: | Fluorescent calpain I & II & papain & 20S proteasome substrate |
CAS | 94367-20-1 |
MW: | 551.6 D |
ab 50,00 €
Artikelnummer: Cay13859-25
The calpains are a family of calcium-dependent cysteine proteases which catalyze limited proteolysis of substrates. PD 150606 is a selective, cell-permeable inhibitor of calpains (Ki = 0.21 µM for µ-calpain (calpain-1) and 0.37 µM for m-calpain (calpain-2)). PD 150606 is commonly used to elucidate the roles for...
Schlagworte: | 3-(4-iodophenyl)-2Z-mercapto-2-propenoic acid |
Anwendung: | Calpain inhibitor |
CAS | 179528-45-1 |
MW: | 306.1 D |
ab 114,00 €
Artikelnummer: G-HUFI01843.96
Anwendung: | ELISA |
Spezies-Reaktivität: | human |
641,00 €
Artikelnummer: NSJ-R32944
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Calpain-2 catalytic subunit is a protein that in humans is encoded by the CAPN2 gene. The calpains, calcium-activated neutral proteases, are nonlysosomal, intracellular cysteine proteases. The mammalian calpains include ubiquitous, stomach-specific, and...
Schlagworte: | Anti-CAPN2, Anti-CANPL2, Anti-CANP 2, Anti-M-calpain, EC=3.4.22.53, Anti-Calpain M-type, Anti-Millimolar-calpain,... |
Anwendung: | WB, IHC (paraffin) |
Wirt: | Rabbit |
Spezies-Reaktivität: | human, mouse, rat |
755,00 €
Artikelnummer: Cay18752-5
Aureusimine B, also known as phevalin, is a natural pyrazinone produced by certain fungi and by Staphylococcus spp., including S. aureus. Its synthesis appears to be initiated by a conserved nonribosomal peptide synthetase that creates a dipeptide (phenylalanine-valine) aldehyde, which then undergoes cyclization and...
Schlagworte: | Phevalin, 3-(1-methylethyl)-6-(phenylmethyl)-2(1H)-pyrazinone |
Anwendung: | Natural pyrazinon, Calpain inhibitor |
CAS | 170713-71-0 |
MW: | 228.3 D |
ab 287,00 €
Artikelnummer: ARG40370.50
Protein function: Calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction. Proteolytically cleaves MYOC at 'Arg-226' (PubMed:17650508). Proteolytically cleaves CPEB3 following neuronal stimulation which abolishes...
Schlagworte: | Anti-CAPN2, Anti-CANPL2, Anti-CANP 2, Anti-M-calpain, EC=3.4.22.53, Anti-Calpain M-type, Anti-Millimolar-calpain,... |
Anwendung: | IHC (paraffin) |
Wirt: | Rabbit |
Spezies-Reaktivität: | human |
520,00 €
Artikelnummer: ARG40359.100
Protein function: Calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction. Proteolytically cleaves MYOC at 'Arg-226' (PubMed:17650508). Proteolytically cleaves CPEB3 following neuronal stimulation which abolishes...
Schlagworte: | Anti-CAPN2, Anti-CANPL2, Anti-CANP 2, Anti-M-calpain, EC=3.4.22.53, Anti-Calpain M-type, Anti-Millimolar-calpain,... |
Anwendung: | WB |
Wirt: | Rabbit |
Spezies-Reaktivität: | human, mouse, rat |
624,00 €
Artikelnummer: ARG40403.100
Protein function: Calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction. Proteolytically cleaves MYOC at 'Arg-226' (PubMed:17650508). Proteolytically cleaves CPEB3 following neuronal stimulation which abolishes...
Schlagworte: | Anti-CAPN2, Anti-CANPL2, Anti-CANP 2, Anti-M-calpain, EC=3.4.22.53, Anti-Calpain M-type, Anti-Millimolar-calpain,... |
Anwendung: | WB |
Wirt: | Rabbit |
Spezies-Reaktivität: | human, mouse, rat |
624,00 €