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PD150606
PD150606

Artikelnummer: TGM-T3525-1mg

Description: PD150606 is a selective nonpeptide calpain inhibitor with neuroprotective activity that inhibits µ-calpains and m-calpains. Inhibits erythrocyanine-induced Ca2+ efflux and interferes with excitotoxicity-dependent motor neuron death. Target: Cysteine Protease. Smiles: OC(=O)C(\S)=C\c1ccc(I)cc1....
Anwendung: Calpain inhibitor
CAS 179528-45-1
MW: 306.12 D
ab 31,00 €
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CAPN2 Protein, Human, Recombinant (His)
CAPN2 Protein, Human, Recombinant (His)

Artikelnummer: TGM-TMPH-01031-100ug

Description: Calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction. Proteolytically cleaves MYOC at 'Arg-226'. Proteolytically cleaves CPEB3 following neuronal stimulation which abolishes CPEB3 translational...
Schlagworte: CANPL2, Calpain large polypeptide L2, Calcium-activated neutral proteinase 2, CAPN2, Millimolar-calpain, Calpain-2...
MW: 82.1 kD
ab 193,00 €
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Calpain-2 catalytic subunit (CAPN2), human, recombinant
Calpain-2 catalytic subunit (CAPN2), human, recombinant

Artikelnummer: CSB-EP004496HU.1

Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 20-700aa. Protein Length: Full Length of Mature Protein. Tag Info: N-terminal 6xHis-tagged. Target Protein Sequence: SHDRAIKYLN QDYEALRNEC LEAGTLFQDP SFPAIPSALG FKELGPYSSK TRGIEWKRPT EICADPQFII GGATRTDICQ GALGDCWLLA AIASLTLNEE ILARVVPLNQ SFQENYAGIF...
Schlagworte: CAPN2, CANP 2, CANPL2, M-calpain, EC=3.4.22.53, Calpain M-type, Millimolar-calpain, Calpain-2 large subunit, Calpain-2...
Anwendung: Activity not tested
Exprimiert in: E.coli
Ursprungsart: human
MW: 82.1 kD
ab 216,00 €
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Anti-CAPN2 Recombinant Monoclonal, clone 17E9
Anti-CAPN2 Recombinant Monoclonal, clone 17E9

Artikelnummer: CSB-RA899086A0HU.100

Isotype: Rabbit IgG. Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Affinity-chromatography. Target Name: CAPN2. Antigen Species: Human
Schlagworte: Anti-CAPN2, Anti-CANPL2, Anti-CANP 2, Anti-M-calpain, EC=3.4.22.53, Anti-Calpain M-type, Anti-Millimolar-calpain,...
Anwendung: ELISA, WB,
Wirt: Rabbit
Spezies-Reaktivität: human
ab 201,00 €
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Anti-CAPN2
Anti-CAPN2

Artikelnummer: CSB-PA247305.100

Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: CAPN2. Antigen Species: Human
Schlagworte: Anti-CAPN2, Anti-CANPL2, Anti-CANP 2, Anti-M-calpain, EC=3.4.22.53, Anti-Calpain M-type, Anti-Millimolar-calpain,...
Anwendung: ELISA, WB
Wirt: Rabbit
Spezies-Reaktivität: human, mouse, rat
ab 165,00 €
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Anti-CAPN2
Anti-CAPN2

Artikelnummer: CSB-PA257142.100

Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: CAPN2. Antigen Species: Human
Schlagworte: Anti-CAPN2, Anti-CANPL2, Anti-CANP 2, Anti-M-calpain, EC=3.4.22.53, Anti-Calpain M-type, Anti-Millimolar-calpain,...
Anwendung: ELISA, WB
Wirt: Rabbit
Spezies-Reaktivität: human, mouse, rat
ab 165,00 €
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Suc-Leu-Tyr-AMC
Suc-Leu-Tyr-AMC

Artikelnummer: Cay10008120-25

The calpains are a family of calcium-dependent cysteine proteases, with calpain I (µ-calpain) requiring micromolar calcium and calpain II (m-calpain) requiring millimolar calcium. Suc-Leu-Tyr-AMC is a fluorescent substrate for calpain I and II and papain (another cysteine protease) that is used for measuring the...
Schlagworte: Suc-LY-AMC, N-(3-carboxy-1-oxopropyl)-L-leucyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-L-tyrosinamide
Anwendung: Fluorescent calpain I & II & papain & 20S proteasome substrate
CAS 94367-20-1
MW: 551.6 D
ab 52,00 €
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Calpain Inhibitor III
Calpain Inhibitor III

Artikelnummer: Cay14283-5

The calpains are a family of calcium-dependent cysteine proteases that catalyze limited proteolysis of substrates. Calpain Inhibitor III is a cell permeable, selective inhibitor of µ-calpain (calpain-1) and m-calpain (calpain-2). Calpain Inhibitor III crosses the blood-brain barrier to inhibit brain cysteine...
Schlagworte: MDL 28170, N-[(1S)-1-[[(1-formyl-2-phenylethyl)amino]carbonyl]-2-methylpropyl]-carbamic acid, phenylmethyl ester
Anwendung: Calpain 1 and 2 inhibitor
CAS 88191-84-8
MW: 382.5 D
ab 44,00 €
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Calpain Inhibitor II
Calpain Inhibitor II

Artikelnummer: Cay15994-10

Calpain inhibitor II is a cell permeable, peptide aldehyde inhibitor of calpain I (Ki = 120 nM), calpain II (Ki = 230 nM), cathepsin B (Ki = 100 nM), and cathepsin L (Ki = 0.6 nM). It has been used to demonstrate the involvement of ubiquitin-proteasome protein degradation in various biological systems.Formal Name:...
Schlagworte: Ac-Leu-Leu-Met-H, ALLM, N-acetyl-L-leucyl-N-[(1S)-1-formyl-3-(methylthio)propyl]-L-leucinamide
Anwendung: Calpain I/II & cathepsin B inhibitor
CAS 110115-07-6
MW: 401.6 D
ab 44,00 €
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PD 150,606
PD 150,606

Artikelnummer: AG-CR1-0066-M005

Cell permeable and selective calpain inhibitor. Interacts with calcium-binding domain of calpain, Neuroprotective, Ca2+permeable AMPA receptor inhibitor, Apoptosis inhibitor .
Schlagworte: 3-(4-Iodophenyl)-2-mercapto-(Z)-2-propenoic acid
Anwendung: Calpain inhibitor
MW: 306,1 D
ab 83,00 €
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PD 150606
PD 150606

Artikelnummer: Cay13859-25

The calpains are a family of calcium-dependent cysteine proteases which catalyze limited proteolysis of substrates. PD 150606 is a selective, cell-permeable inhibitor of calpains (Ki = 0.21 µM for µ-calpain (calpain-1) and 0.37 µM for m-calpain (calpain-2)). PD 150606 is commonly used to elucidate the roles for...
Schlagworte: 3-(4-iodophenyl)-2Z-mercapto-2-propenoic acid
Anwendung: Calpain inhibitor
CAS 179528-45-1
MW: 306.1 D
ab 116,00 €
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Human CAPN2 / Calpain 2 ELISA Kit
Human CAPN2 / Calpain 2 ELISA Kit

Artikelnummer: G-HUFI01843.96

Anwendung: ELISA
Spezies-Reaktivität: human
641,00 €
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