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Zu "K03462" wurden 165 Artikel gefunden!
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Artikelnummer: AG-45A-0006YEK-KI01
Nicotinamide phosphoribosyltransferase (Nampt, pre-B cell colony-enhancing factor, PBEF, Visfatin) is an 52kDA adipokine secreted by adipose tissue and involved in the biosynthesis of nicotinamide adenine dinucleotide (NAD+). Two forms of Nampt exist, an intracellular form (iNampt) and an extracellular form...
Schlagworte: | PBEF, NAMPT, Nampt, Visfatin, NAmPRTase, EC=2.4.2.12, Pre-B cell-enhancing factor, Pre-B-cell colony-enhancing factor 1,... |
Anwendung: | ELISA |
Spezies-Reaktivität: | human |
ab 693,00 €
Artikelnummer: Cay16411-100
beta-Nicotinamide mononucleotide (beta-NMN) is an intermediate in the biosynthesis of nicotinamide adenine dinucleotide (NAD+, Cay-16077). Nicotinamide phosphoribosyltransferase (Nampt) catalyzes the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to generate beta-NMN, which is subsequently...
Schlagworte: | beta-NMN, 3-(aminocarbonyl)-1-(5-O-phosphono-beta-D-ribofuranosyl)-pyridinium, inner salt |
Anwendung: | NAD biosynthesis intermediate |
CAS | 1094-61-7 |
MW: | 334.2 D |
ab 61,00 €
Artikelnummer: TGM-TMPJ-00968-10ug
Description: Pre-B cell colony enhancing factor (PBEF) was originally identified as a cytokine that potentiated the clonal expansion and differentiation of pre-B cells, but it is also acknowledged to be the ubiquitous intracellular enzyme nicotinamide phosphoribosyltranferase (NAMPT) and the adipokine "visfatin"....
Schlagworte: | PBEF, Nicotinamide phosphoribosyltransferase, PBEF1, Visfatin, NAmPRTase, NAMPT, Pre-B cell-enhancing factor, Pre-B-cell... |
MW: | 55 kD |
ab 116,00 €
Artikelnummer: TGM-TMPH-02810-100ug
Description: NAMPT Protein, Mouse, Recombinant (His) is expressed in yeast with N-10xHis tag. The predicted molecular weight is 57.9 kDa and the accession number is Q99KQ4.
Schlagworte: | Nicotinamide phosphoribosyltransferase, Nampt, Visfatin, Pre-B-cell colony-enhancing factor 1 homolog |
MW: | 57.9 kD |
ab 281,00 €
Artikelnummer: TGM-TMPH-03760-100ug
Description: NAMPT Protein, Mouse, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 55.6 kDa and the accession number is Q99KQ4.
Schlagworte: | Nampt, Nicotinamide phosphoribosyltransferase, Visfatin, Pre-B-cell colony-enhancing factor 1 homolog |
MW: | 55.6 kD |
ab 390,00 €
Artikelnummer: TGM-TMPH-03761-100ug
Description: NAMPT Protein, Mouse, Recombinant (HA & His) is expressed in E. coli expression system with N-6xHis and C-HA tag. The predicted molecular weight is 60.6 kDa and the accession number is Q99KQ4.
Schlagworte: | Visfatin, Nampt, Nicotinamide phosphoribosyltransferase, Pre-B-cell colony-enhancing factor 1 homolog |
MW: | 60.6 kD |
ab 236,00 €
Artikelnummer: TGM-TMPY-02577-50ug
Description: Nicotinamide phosphoribosyltransferase (NAMPT), also known as pre-B-cell colony-enhancing factor 1 (PBEF1) or visfatin, is an enzyme belonging to the family of glycosyltransferases, to be specific, the pentosyltransferases. This enzyme participates in nicotinate and nicotinamide metabolism. This enzyme...
Schlagworte: | VISFATIN, PBEF, PBEF1, 1110035O14Rik, VF, nicotinamide phosphoribosyltransferase |
MW: | 83.3 kD |
304,00 €
Artikelnummer: TGM-T18477-100mg
Description: NAMPT inhibitor-linker 1, a drug-linker conjugate for ADC, integrates an NAMPT inhibitor (as a payload) with a linker. In the formulation of ADC-3, it pairs with an anti-c-Kit monoclonal antibody, demonstrating strong efficacy against c-Kit expressing cell lines, specifically GIST-T1 and NCI-H526, where...
Anwendung: | NAMPT inhibitor |
CAS | 2241019-57-6 |
MW: | 668.71 D |
Bitte fragen Sie den aktuellen Preis für diesen Artikel an.
Artikelnummer: TGM-T18478-100mg
Description: NAMPT inhibitor-linker 2, a drug-linker conjugate for antibody-drug conjugates (ADCs), comprises an NAMPT inhibitor payload and a linker. When combined with an anti-c-Kit monoclonal antibody to form ADC-4, it demonstrates potent efficacy against c-Kit expressing cell lines, including GIST-T1 and...
Anwendung: | NAMPT inhibitor |
CAS | 2241014-82-2 |
MW: | 624.66 D |
Bitte fragen Sie den aktuellen Preis für diesen Artikel an.
Artikelnummer: TGM-T1880-100mg
Description: The P7C3 class of neuroprotective aminopropyl carbazoles has been shown to block neuronal cell death in models of neurodegeneration. We now show that P7C3 molecules additionally preserve axonal integrity after injury, before neuronal cell death occurs, in a rodent model of blast-mediated traumatic brain...
Anwendung: | Neuroprotective |
CAS | 301353-96-8 |
MW: | 474.19 D |
ab 43,00 €
Artikelnummer: TGM-T6682-100mg
Description: STF-118804, a highly specific NAMPT inhibitor, reduces the viability of most B-ALL cell lines with an IC50 of less than 10 nM. Target: NAMPT, Apoptosis. Smiles: Cc1oc(nc1CS(=O)(=O)c1ccc(C)cc1)-c1ccc(cc1)C(=O)NCc1cccnc1. References: Matheny CJ, et al. Chem Biol. 2013, 20(11), 1352-1363.
Schlagworte: | STF118804, STF 118804 |
Anwendung: | NAMPT inhibitor |
CAS | 894187-61-2 |
MW: | 461.53 D |
ab 31,00 €
Artikelnummer: A300-372A
Protein function: Catalyzes the condensation of nicotinamide with 5- phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, an intermediate in the biosynthesis of NAD. It is the rate limiting component in the mammalian NAD biosynthesis pathway. The secreted form behaves both as a cytokine with...
Schlagworte: | Anti-PBEF, Anti-NAMPT, Anti-Nampt, Anti-Visfatin, Anti-NAmPRTase, EC=2.4.2.12, Anti-Pre-B cell-enhancing factor,... |
Anwendung: | WB, IP, IHC |
Wirt: | Rabbit |
Spezies-Reaktivität: | human, mouse |
ab 178,00 €