Zu "K03164" wurden 235 Artikel gefunden!
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Doxorubicin (hydrochloride)
Artikelnummer: Cay15007-5
Doxorubicin is an anthracycline antitumor antibiotic that inhibits DNA topoisomerase II by inducing double-stranded DNA breaks. By intercalating within DNA, doxorubicin inhibits nucleic acid synthesis and induces apoptosis by inducing the accumulation of the p53 tumor suppressor protein.Formal Name:...
| Schlagworte: | DOX,... |
| Anwendung: | DNA topoisomerase II inhibitor, Antitumor agent |
| CAS | 25316-40-9 |
| MW: | 580 D |
ab 44,00 €
-9 %
NEU
Anti-TOP2A
Artikelnummer: ABS-KC-589.100
Protein function: Key decatenating enzyme that alters DNA topology by binding to two double-stranded DNA molecules, generating a double-stranded break in one of the strands, passing the intact strand through the broken strand, and religating the broken strand (PubMed:17567603, PubMed:18790802, PubMed:22013166,...
| Schlagworte: | Anti-DNA topoisomerase 2-alpha, Anti-DNA topoisomerase II, Anti-alpha isozyme, TOP2A Antibody |
| Anwendung: | IHC |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
206,00 €
ab 187,46 €
-9 %
NEU
Anti-TOP2A
Artikelnummer: ABS-KC-590.100
Protein function: Key decatenating enzyme that alters DNA topology by binding to two double-stranded DNA molecules, generating a double-stranded break in one of the strands, passing the intact strand through the broken strand, and religating the broken strand (PubMed:17567603, PubMed:18790802, PubMed:22013166,...
| Schlagworte: | Anti-DNA topoisomerase 2-alpha, Anti-DNA topoisomerase II, Anti-alpha isozyme, TOP2A Antibody |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
232,00 €
ab 211,12 €
-9 %
NEU
Anti-TOP2A
Artikelnummer: ABS-KC-591.100
Protein function: Key decatenating enzyme that alters DNA topology by binding to two double-stranded DNA molecules, generating a double-stranded break in one of the strands, passing the intact strand through the broken strand, and religating the broken strand (PubMed:17567603, PubMed:18790802, PubMed:22013166,...
| Schlagworte: | Anti-DNA topoisomerase 2-alpha, Anti-DNA topoisomerase II, Anti-alpha isozyme, TOP2A Antibody |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
232,00 €
ab 211,12 €
-9 %
NEU
Anti-TOP2B
Artikelnummer: ABS-KC-745.100
Protein function: Key decatenating enzyme that alters DNA topology by binding to two double-stranded DNA molecules, generating a double-stranded break in one of the strands, passing the intact strand through the broken strand, and religating the broken strand. [The UniProt Consortium]
| Schlagworte: | Anti-DNA topoisomerase 2-beta, Anti-DNA topoisomerase II, Anti-beta isozyme, TOP2B Antibody |
| Anwendung: | IHC |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
206,00 €
ab 187,46 €
-9 %
NEU
Anti-TOP2B
Artikelnummer: ABS-KC-746.100
Protein function: Key decatenating enzyme that alters DNA topology by binding to two double-stranded DNA molecules, generating a double-stranded break in one of the strands, passing the intact strand through the broken strand, and religating the broken strand. [The UniProt Consortium]
| Schlagworte: | Anti-DNA topoisomerase 2-beta, Anti-DNA topoisomerase II, Anti-beta isozyme, TOP2B Antibody |
| Anwendung: | IHC |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
206,00 €
ab 187,46 €
-9 %
NEU
Anti-TOP2B
Artikelnummer: ABS-KC-747.100
Protein function: Key decatenating enzyme that alters DNA topology by binding to two double-stranded DNA molecules, generating a double-stranded break in one of the strands, passing the intact strand through the broken strand, and religating the broken strand. [The UniProt Consortium]
| Schlagworte: | Anti-DNA topoisomerase 2-beta, Anti-DNA topoisomerase II, Anti-beta isozyme, TOP2B Antibody |
| Anwendung: | IHC |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
206,00 €
ab 187,46 €
-9 %
NEU
Anti-TOP2A
Artikelnummer: ABS-OC-097.100
Protein function: Key decatenating enzyme that alters DNA topology by binding to two double-stranded DNA molecules, generating a double-stranded break in one of the strands, passing the intact strand through the broken strand, and religating the broken strand (PubMed:17567603, PubMed:18790802, PubMed:22013166,...
| Schlagworte: | Anti-DNA topoisomerase 2-alpha, Anti-DNA topoisomerase II, Anti-alpha isozyme, TOP2A Antibody |
| Anwendung: | IHC |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
206,00 €
ab 187,46 €
-9 %
NEU
TOP2B (human) Antibody Pair
Artikelnummer: ABS-ES-534.50
Protein function: Key decatenating enzyme that alters DNA topology by binding to two double-stranded DNA molecules, generating a double-stranded break in one of the strands, passing the intact strand through the broken strand, and religating the broken strand. [The UniProt Consortium]
| Schlagworte: | Anti-TOP2B, Anti-DNA topoisomerase 2-beta, Anti-DNA topoisomerase II, beta isozyme |
| Anwendung: | ELISA |
| Wirt: | Mouse/Mouse |
| Spezies-Reaktivität: | human |
1.080,00 €
982,80 €
-9 %
NEU
TOP2B (human) Antibody Pair
Artikelnummer: ABS-ES-535.50
Protein function: Key decatenating enzyme that alters DNA topology by binding to two double-stranded DNA molecules, generating a double-stranded break in one of the strands, passing the intact strand through the broken strand, and religating the broken strand. [The UniProt Consortium]
| Schlagworte: | Anti-TOP2B, Anti-DNA topoisomerase 2-beta, Anti-DNA topoisomerase II, beta isozyme |
| Anwendung: | ELISA |
| Wirt: | Mouse/Mouse |
| Spezies-Reaktivität: | human |
1.080,00 €
982,80 €
-9 %
NEU
TOP2B (human) Antibody Pair
Artikelnummer: ABS-ES-533.50
Protein function: Key decatenating enzyme that alters DNA topology by binding to two double-stranded DNA molecules, generating a double-stranded break in one of the strands, passing the intact strand through the broken strand, and religating the broken strand. [The UniProt Consortium]
| Schlagworte: | Anti-TOP2B, Anti-DNA topoisomerase 2-beta, Anti-DNA topoisomerase II, beta isozyme |
| Anwendung: | ELISA |
| Wirt: | Mouse/Mouse |
| Spezies-Reaktivität: | human |
1.080,00 €
982,80 €
Etoposide
Artikelnummer: Cay12092-25
Etoposide is a plant alkaloid and an inhibitor of topoisomerase II (IC50 = 60.3 µM). It inhibits proliferation of a variety of adenocarcinoma cells (IC50s = 0.005-12,200 µM) and human umbilical vein endothelial (HUVEC) cells (IC50 = 0.249 µM). It reduces tumor growth in an Ma human embryonal carcinoma mouse...
| Schlagworte: | EPE, NSC 141540, VP-16-123,... |
| Anwendung: | DNA Topoisomerase II inhibitor, Apoptosis inducer |
| CAS | 33419-42-0 |
| MW: | 588.6 D |
ab 28,00 €