Zu "K03156" wurden 560 Artikel gefunden!
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Tumor Necrosis Factor alpha, human recombinant (rHuTNF-a)
Artikelnummer: 50435.10
Tumor necrosis factor is a cytokine involved in systemic inflammation and is a member of a group of cytokines that all stimulate the acute phase reaction. TNF is mainly secreted by macrophages. TNF causes apoptotic cell death, cellular proliferation, differentiation, inflammation, tumorigenesis and viral...
| Schlagworte: | TNF-alpha, Tumor necrosis factor ligand superfamily member 2, TNF-a, Cachectin, DIF, TNFA, TNFSF2 |
| Anwendung: | Cell culture |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 17.5 kD |
ab 94,00 €
Tumor Necrosis Factor alpha, mouse recombinant (rmTNF-a)
Artikelnummer: 52624.5
Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain...
| Schlagworte: | TNF-alpha, Tumor necrosis factor ligand superfamily member 2, TNF-a, Cachectin, DIF, TNFA, TNFSF2 |
| Anwendung: | Cell culture |
| Exprimiert in: | E.coli |
| Ursprungsart: | mouse |
| MW: | 17.3 kD |
ab 94,00 €
TNF alpha, Human
Artikelnummer: CR-C01047-20UG
Sequence: MVRSSSRTPS DKPVAHVVAN PQAEGQLQWL NRRANALLAN GVELRDNQLV VPSEGLYLIY SQVLFKGQGC PSTHVLLTHT ISRIAVSYQT VNLLSAIKSP CQRETPEGAE AKPWYEPIYL GGVFQLEKGD RLSAEINRPD YLDFAESGQV with polyhistidine tag at the C-terminus Endotoxin level: <0.1 EU per 1 µg of the protein by the LAL method. Protein function: Cytokine that...
| Schlagworte: | TNF, TNFA |
| Anwendung: | Cell culture |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
ab 96,00 €
Tanshinone IIA
Artikelnummer: TGM-T2906-20mg
Description: Tanshinone IIA (Tanshinone B) is a diterpene quinone natural product that targets the protein kinase domain of VEGF/VEGFR2. Tanshinone IIA inhibits angiogenesis and exhibits anti-inflammatory, antioxidant, and therapeutic activities against coronary heart disease. Target: VEGFR. Smiles:...
| Schlagworte: | Tanshinone B, Dan Shen ketone |
| Anwendung: | Anti-inflammatory agent |
| CAS | 568-72-9 |
| MW: | 294.34 D |
50,00 €
TNF-alpha Antagonist
Artikelnummer: TGM-T36127-1mg
Description: TNF-alpha antagonist is an exocyclic peptide that mimics the critical TNF-alpha recognition loop on TNF receptor I complex and, thus, prevents ligand interaction with the receptor. By blocking the TNF receptor ligand contact site, this peptide interferes with both activating receptor activator of...
| Anwendung: | TNFA antagonist |
| CAS | 199999-60-5 |
| MW: | 1226.39 D |
ab 289,00 €
Quinolactacin A
Artikelnummer: TGM-T38338-1mg
Description: Quinolactactin A is a quinolone fungal metabolite originally isolated from Penicillium. It inhibits TNF production induced by LPS in murine peritoneal macrophages (IC50 = 12.2 µg/ml). It is not active against a variety of bacteria, fungi, and yeasts. Quinolactacin A is a mixture of quinolactacin A1 and...
| Anwendung: | Quinolone fungal metabolite |
| CAS | 319917-25-4 |
| MW: | 270.332 D |
ab 208,00 €
Etanercept
Artikelnummer: TGM-T37445-100mg
Description: Etanercept is a dimeric fusion protein that serves as a competitive TNF inhibitor by binding to TNF. It effectively inhibits the binding of both TNF-alpha and TNF-beta to the TNF receptors on cell surfaces, thereby rendering TNF biologically inactive. Etanercept has demonstrated efficacy in treating...
| Anwendung: | Targets tumor necrosis factor superfamily, member 2 (TNF, TNFA) |
| CAS | 185243-69-0 |
ab 321,00 €
Golimumab
Artikelnummer: TGM-T76711-100mg
Description: Golimumab (CNTO-148) is a potent humanized anti-TNFalpha IgG1kappa monoclonal antibody with anti-inflammatory and anticancer activity. It inhibits the production of IL-6 and IL-1beta, induces apoptosis, and can be used to prevent inflammation and destruction of cartilage or bone. This makes Golimumab...
| Schlagworte: | CNTO-148, SCH 900259, MK-8259 |
ab 290,00 €
TNF alpha Protein, Rabbit, Recombinant
Artikelnummer: TGM-TMPJ-00779-100ug
Description: Tumor necrosis factor alpha (TNFalpha) is the prototypic ligand of the TNF superfamily. TNFalpha forms a homotrimer and functions by activating two types of receptors TNF-R1 (TNF receptor type 1,p55R) and TNF-R2 (TNF receptor type 2,p75R). TNFalpha is a pleiotropic cytokine that is capable to promote...
| Schlagworte: | TNFSF2, TNF, TNF-Alpha, TNFA, Tumor Necrosis Factor Ligand Superfamily Member 2, TNF-a, Tumor Necrosis Factor, TNF-alpha,... |
| MW: | 18 kD |
ab 90,00 €
Infliximab
Artikelnummer: TGM-T9921-1mg
Description: Infliximab is a humanized antibody against tumor necrosis factor alpha TNF-alpha) that is used in the treatment of Crohn's disease and rheumatoid arthritis. Target: TNF. References: Dahlén R, et al. Infliximab inhibits activation and effector functions of peripheral blood T cells in vitro from patients...
| MW: | 149 kD |
ab 96,00 €
TNF alpha Protein, Cynomolgus, Recombinant (His)
Artikelnummer: TGM-TMPK-00119-100ug
Description: TNF alpha Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with N-His tag. The predicted molecular weight is 18.35 kDa and the accession number is P79337.
| Schlagworte: | TNF, DIF, Cachectin, TNFalpha, TNFSF2, TNF-alpha, APC1 protein, TNFalpha, TNF alpha, TNFA, TNF-alpha, TNFSF1A, TNFATNF |
| MW: | 18.35 kD |
ab 477,00 €
TNF alpha Protein, Human, Recombinant (His & Avi)
Artikelnummer: TGM-TMPK-00120-100ug
Description: TNF alpha Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 20.3 kDa and the accession number is P01375.
| Schlagworte: | TNF-alpha, TNFSF1A, TNFATNF, TNFA, TNFalpha, Cachectin, DIF, APC1 protein, TNFalpha, TNF alpha, TNF-alpha, TNFSF2, TNF |
| MW: | 20.3 kD |
ab 339,00 €