Zu "K03083" wurden 170 Artikel gefunden!
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CHIR99021
Artikelnummer: Cay13122-1
CHIR99021 is an aminopyrimidine derivative that inhibits GSK3alpha and GSK3beta with IC50 values of 10 and 6.7 nM, respectively. When tested against twenty different protein kinases, this inhibitor shows greater than 500-fold selectivity for GSK3. CHIR99021 activates glycogen synthesis in CHO-IR cells (EC50 = 0.763...
| Schlagworte: | CT 99021,... |
| Anwendung: | GSK3alpha and GSK3beta inhibitor |
| CAS | 252917-06-9 |
| MW: | 465.3 D |
ab 44,00 €
NEU
Anti-GSK3B
Artikelnummer: ABS-KC-6249.100
Protein function: Constitutively active protein kinase that acts as a negative regulator in the hormonal control of glucose homeostasis, Wnt signaling and regulation of transcription factors and microtubules, by phosphorylating and inactivating glycogen synthase (GYS1 or GYS2), EIF2B, CTNNB1/beta-catenin, APC,...
| Schlagworte: | Anti-Glycogen synthase kinase-3 beta, Anti-GSK-3 beta, Anti-Serine/threonine-protein kinase GSK3B, GSK3B Antibody |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human, rat, mouse |
ab 232,00 €
NEU
Anti-GSK3B
Artikelnummer: ABS-KC-6250.100
Protein function: Constitutively active protein kinase that acts as a negative regulator in the hormonal control of glucose homeostasis, Wnt signaling and regulation of transcription factors and microtubules, by phosphorylating and inactivating glycogen synthase (GYS1 or GYS2), EIF2B, CTNNB1/beta-catenin, APC,...
| Schlagworte: | Anti-Glycogen synthase kinase-3 beta, Anti-GSK-3 beta, Anti-Serine/threonine-protein kinase GSK3B, GSK3B Antibody |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human, rat, mouse |
ab 232,00 €
NEU
Anti-GSK3B
Artikelnummer: ABS-KC-6251.100
Protein function: Constitutively active protein kinase that acts as a negative regulator in the hormonal control of glucose homeostasis, Wnt signaling and regulation of transcription factors and microtubules, by phosphorylating and inactivating glycogen synthase (GYS1 or GYS2), EIF2B, CTNNB1/beta-catenin, APC,...
| Schlagworte: | Anti-Glycogen synthase kinase-3 beta, Anti-GSK-3 beta, Anti-Serine/threonine-protein kinase GSK3B, GSK3B Antibody |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human, rat, mouse |
ab 232,00 €
NEU
Anti-GSK3B
Artikelnummer: ABS-KC-6282.100
Protein function: Constitutively active protein kinase that acts as a negative regulator in the hormonal control of glucose homeostasis, Wnt signaling and regulation of transcription factors and microtubules, by phosphorylating and inactivating glycogen synthase (GYS1 or GYS2), EIF2B, CTNNB1/beta-catenin, APC,...
| Schlagworte: | Anti-Glycogen synthase kinase-3 beta, Anti-GSK-3 beta, Anti-Serine/threonine-protein kinase GSK3B, GSK3B Antibody |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human, mouse, rat |
ab 232,00 €
NEU
Anti-GSK3B
Artikelnummer: ABS-KC-6339.100
Protein function: Constitutively active protein kinase that acts as a negative regulator in the hormonal control of glucose homeostasis, Wnt signaling and regulation of transcription factors and microtubules, by phosphorylating and inactivating glycogen synthase (GYS1 or GYS2), EIF2B, CTNNB1/beta-catenin, APC,...
| Schlagworte: | Anti-Glycogen synthase kinase-3 beta, Anti-GSK-3 beta, Anti-Serine/threonine-protein kinase GSK3B, GSK3B Antibody |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human, mouse, rat |
ab 232,00 €
GSK-3beta inhibitor 3
Artikelnummer: TGM-T35554-100mg
Description: GSK-3beta inhibitor 3 is a potent, selective, and irreversible covalent inhibitor of glycogen synthase kinase 3beta (GSK-3beta) with an IC50 of 6.6 µM, and can be used to study acute promyelocytic leukemia. Target: Apoptosis, GSK-3. Smiles: Fc1ccc(cc1)C1CC(=O)N(C(=O)C=C)c2ccccc2S1. References: Zhang P,...
| Anwendung: | GSK-3beta inhibitor |
| CAS | 1448990-73-5 |
| MW: | 327.37 D |
ab 98,00 €
GSK-3beta inhibitor 8
Artikelnummer: TGM-T35556-1mg
Description: GSK-3beta inhibitor 8 (GSK3beta Inhibitor XVIII) is a potent and selective GSK-3beta inhibitor with an IC50 value of 64 nM.GSK-3beta inhibitor 8 is a thienopyrimidine derivative that negatively regulates the Wnt signaling pathway and stimulates beta-cell proliferation. Target: GSK-3, Wnt/beta-catenin....
| Schlagworte: | GSK3beta Inhibitor XVIII |
| Anwendung: | GSK-3beta inhibitor |
| CAS | 1139875-74-3 |
| MW: | 413.92 D |
110,00 €
Manzamine A
Artikelnummer: TGM-T27977-1mg
Description: Manzamine A is a GSK-3 inhibitor and vacuolar ATPase uncoupler found in marine sponges. It inhibits autophagy and tumor growth in cancer models, suppresses foam cell formation in macrophages, prevents growth of gram negative and gram positive bacteria, and decreases tau hyperphosphorylation. Target:...
| Schlagworte: | Keramamine A |
| Anwendung: | Antiinflammatory GSK-3beta inhibitor |
| CAS | 104196-68-1 |
| MW: | 548.775 D |
591,00 €
GSK3beta Inhibitor XI
Artikelnummer: TGM-T36088-1mg
Description: GSK3beta Inhibitor XI has GSK3beta inhibitory effect. Target: Others. Smiles: OCCCn1cc(C2=C(C(=O)NC2=O)c2cnccn2)c2cccnc12 , t:7,
| Schlagworte: | GSK3beta Inhibitor XI |
| Anwendung: | GSK3beta inhibitor |
| CAS | 626604-39-5 |
| MW: | 349.35 D |
701,00 €
Tideglusib
Artikelnummer: TGM-T3067-100mg
Description: Tideglusib (NP031112), a non-ATP competitive inhibitor of glycogen synthase kinase 3 (GSK-3), is with anti-inflammatory and neuroprotective activities. Target: GSK-3. Smiles: O=c1sn(-c2cccc3ccccc23)c(=O)n1Cc1ccccc1. References: Domínguez JM, et al. J Biol Chem, 2012, 287(2), 893-90
| Schlagworte: | NP-12, NP031112 |
| Anwendung: | Neuroprotective, GSK3beta inhibitor |
| CAS | 865854-05-3 |
| MW: | 334.39 D |
ab 40,00 €
CP21R7
Artikelnummer: TGM-T3684-100mg
Description: CP21R7 (CP21) is an effective and specific GSK3beta inhibitor. It is used as an activator of stem cells prior to the induction of differentiation of stem cells to smooth muscle and endothelial cells. CP21R7 can be combined with BMP4 to commit human pluripotent stem cells to a mesodermal fate. Target:...
| Schlagworte: | CP21 |
| Anwendung: | Potent, selective GSK-3beta inhibitor |
| CAS | 125314-13-8 |
| MW: | 317.34 D |
ab 57,00 €