Zu "K02732" wurden 26 Artikel gefunden!
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Bortezomib
Artikelnummer: Cay10008822-1
Bortezomib is a dipeptide boronic acid derivative that reversibly inhibits the 20S proteasome (Ki = 0.6 nM). It binds the beta5-subunit of the 20S proteasome and selectively inhibits chymotryptic activity. In part by blocking the degradation of tumor-suppressing and proapoptotic proteins, bortezomib drives cell...
| Schlagworte: | LDP-341, MG-341, MLN341, NSC 681239, PS-341,... |
| Anwendung: | Proteasome subunit beta type-1/5 inhibitor |
| CAS | 179324-69-7 |
| MW: | 384.2 D |
ab 43,00 €
Human proteasome (prosome, macropain) subunit beta type 1...
Artikelnummer: ELK-ELK8540.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human proteasome. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human...
| Schlagworte: | PSC5, PSMB1, Macropain subunit C5, Proteasome gamma chain, Proteasome component C5, Proteasome subunit beta type-1,... |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
ab 365,00 €
Bortezomib, Free Base (Velcade, MG-341, PS-341, CAS...
Artikelnummer: LC-B-1408_100mg
Soluble in DMSO at 200 mg/mL, soluble in ethanol at 200 mg/mL, very poorly soluble in water, maximum solubility in plain water is estimated to be about 5-10 µM, buffers, serum, or other additives may increase or decrease the aqueous solubility
| Schlagworte: | LDP-341, MG-341, MLN341, NSC 681239, PS-341, Velcade,... |
| Anwendung: | Proteasome subunit beta type-1/5 inhibitor |
| CAS | 179324-69-7 |
| MW: | 384,24 D |
ab 80,00 €
Bortezomib
Artikelnummer: LKT-B5871.5
Proteasome inhibitor.
| Schlagworte: | Velcade, PS-341, [(1R)-3-Methyl-1-[[(2S)-3-phenyl-2-(pyrazine-2-carbonylamino)propanoyl] amino]butyl]boronic acid |
| Anwendung: | Proteasome subunit beta type-1 inhibitor, proteasome subunit beta type-5 inhibitor |
| CAS | 179324-69-7 |
| MW: | 384.24 D |
ab 149,00 €
![Z-Leu-Leu-Glu-AMC [Z-LLE-AMC]](https://www.biomol.com/media/image/0e/8d/00/SBB-PS0006-M002_200x200.png "Z-Leu-Leu-Glu-AMC [Z-LLE-AMC]")
Z-Leu-Leu-Glu-AMC [Z-LLE-AMC]
Artikelnummer: SBB-PS0006-M002
Lyophilized powder. Soluble in DMSO. Z-LLE-AMC is a fluorogenic peptide substrate for measuring caspase-like activity of the proteasome. Hydrolysis of this substrate by the beta1-subunit of the 20S proteasome is monitored by observing fluorescence at an Excitation wavelength of 345nm and Emission at 445nm. This...
| Schlagworte: | Proteasome Substrate II |
| Anwendung: | Fluorogenic peptide substrate |
| MW: | 664,8 D |
234,00 €
Anti-PSMB1
Artikelnummer: ARG56253.100
Protein function: Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory particles. Associated with two 19S regulatory particles, forms the 26S proteasome...
| Schlagworte: | Anti-PSC5, Anti-PSMB1, Anti-Macropain subunit C5, Anti-Proteasome gamma chain, Anti-Proteasome component C5,... |
| Anwendung: | WB, ICC, IF |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
624,00 €
![Delanzomib [CEP-18770]](https://www.biomol.com/media/image/dd/19/42/AG-CR1-3673-M001_200x200.png "Delanzomib [CEP-18770]")
Delanzomib [CEP-18770]
Artikelnummer: AG-CR1-3673-M025
Synthetic. Chemical. CAS: 847499-27-8. Formula: C21H28BN3O5. MW: 413.3. Synthetic. Potent, selective, reversible orally bioavailable proteasome inhibitor. Synthetic P2 threonine boronic acid. Targets the chymotrypsin-like beta5 subunit of the constitutive 20S proteasome (IC50=3.8nM). Cross-reacts and inhibits the...
| Schlagworte: | NPH 007098, CT 47098, CIP 18770,... |
| Anwendung: | Proteasome inhibitor |
| CAS | 847499-27-8 |
| MW: | 413,3 D |
ab 33,00 €
![VR23 [Proteasome Inhibitor]](https://www.biomol.com/media/image/a3/db/0c/AG-CR1-3676-M001_200x200.png "VR23 [Proteasome Inhibitor]")
VR23 [Proteasome Inhibitor]
Artikelnummer: AG-CR1-3676-M025
Synthetic. Chemical. CAS: 1624602-30-7. Formula: C19H16ClN5O6S. MW: 477.9. Synthetic. Potent selective and reversible chloroquine derivative 20S proteasome inhibitor (all proteolytic subunits). Targets the trypsin-like beta2 subunit of the constitutive 20S proteasome (IC50=1nM). Cross-reacts and inhibits the...
| Schlagworte: | 7-Chloro-4-[4-[(2,4-dinitrophenyl)sulfonyl]-1-piperazinyl]quinoline |
| Anwendung: | Proteasome inhibitor |
| CAS | 1624602-30-7 |
| MW: | 477,9 D |
ab 33,00 €
K-7174 (hydrochloride)
Artikelnummer: Cay32773-25
K-7174 is a 20S proteasome inhibitor. It inhibits the beta1, beta2, and beta5 catalytic subunits of the 20S proteasome when used at a concentration of 5 µM. K-7174 (10 µM) reduces TNF-alpha- or IL-1beta-induced adherence of U937 monocytes to human umbilical vein endothelial cells (HUVECs) in a co-culture model of...
| Schlagworte: | hexahydro-1,4-bis[(4E)-5-(3,4,5-trimethoxyphenyl)-4-penten-1-yl]-1H-1,4-diazepine, dihydrochloride |
| Anwendung: | 20S proteasome inhibitor |
| CAS | 191089-60-8 |
| MW: | 641.7 D |
ab 130,00 €
Anti-PSMB1
Artikelnummer: ATA-HPA029635.100
Protein function: Non-catalytic component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory particles. Associated with two 19S regulatory particles, forms the...
| Schlagworte: | Anti-PSC5, Anti-PSMB1, Anti-Macropain subunit C5, Anti-Proteasome gamma chain, Anti-Proteasome component C5,... |
| Anwendung: | ICC, IHC, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 335,00 €
Anti-PSMB1
Artikelnummer: ATA-HPA029637.100
Protein function: Non-catalytic component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory particles. Associated with two 19S regulatory particles, forms the...
| Schlagworte: | Anti-PSC5, Anti-PSMB1, Anti-Macropain subunit C5, Anti-Proteasome gamma chain, Anti-Proteasome component C5,... |
| Anwendung: | WB, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
446,00 €
Anti-Psmb1
Artikelnummer: NSJ-RQ6511
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Proteasome subunit beta type-1 also known as 20S proteasome subunit beta-6 (based on systematic nomenclature) is a protein that in humans is encoded by the PSMB1 gene. The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S...
| Schlagworte: | Anti-Psmb1, Anti-Macropain subunit C5, Anti-Proteasome gamma chain, Anti-Proteasome component C5, Anti-Proteasome subunit... |
| Anwendung: | WB, FC, Direct ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | mouse, rat |
755,00 €