Zu "K02622" wurden 24 Artikel gefunden!
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Nalidixic Acid
Artikelnummer: Cay19807-10
Nalidixic acid is a quinolone antibiotic. It is active against E. coli, Pasturella, K. pneumoniae, A. aerogenes, Proteus, Salmonella, and Shigella with minimum bacteriostatic concentrations (MBCs) ranging from 0.5 to 25 µg/ml. Nalidixic acid increases survival in mouse models of systemic K. pneumoniae, A. aerogenes,...
| Schlagworte: | NSC 82174, WIN 18,320, 1-ethyl-7-methyl-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid |
| Anwendung: | Antibiotic, DNA gyrase / topoisomerase IV inhibitor |
| CAS | 389-08-2 |
| MW: | 232.2 D |
ab 43,00 €
Enoxacin
Artikelnummer: Cay16956-500
Enoxacin is a fluoroquinolone antibiotic. It is active against clinical isolates of a variety of Gram-positive and Gram-negative bacteria, including S. aureus, E. coli, K. pneumoniae, P. aeruginosa, and S. marcescens (MIC50s = 1, 0.12, 0.25, 0.5, and 1 mg/L, respectively). Enoxacin inhibits S. aureus DNA gyrase...
| Schlagworte: | NSC 629661, 1-ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-1,8-naphthyridine-3-carboxylic acid |
| Anwendung: | Antibiotic, Bacterial DNA gyrase / topoisomerase IV inhibitor |
| CAS | 74011-58-8 |
| MW: | 320.3 D |
ab 60,00 €
Levofloxacin (hydrate)
Artikelnummer: Cay20382-5
Levofloxacin is a fluoroquinolone antibiotic and the active stereoisomer of ofloxacin (Cay-22891). It is active against S. aureus, S. epidermidis, B. subtilis, E. coli, P. aeruginosa, and K. pneumoniae (MICs = 0.25, 0.25, 0.5, 0.03, 4, and 0.25 µg/ml, respectively). Levofloxacin inhibits S. aureus DNA gyrase and...
| Schlagworte: | MP-376,... |
| Anwendung: | Antibacterial, nucleic acid biosynthesis inhibitor |
| CAS | 138199-71-0 |
| MW: | 361.4 D |
ab 39,00 €
Ofloxacin
Artikelnummer: Cay22891-1
Ofloxacin is a broad-spectrum fluoroquinolone antibiotic that prevents supercoiling of bacterial chromosomes by DNA gyrase. It is active against Gram-positive and Gram-negative bacteria with MIC90s ranging from 0.39 to 3.13 µg/ml for clinical isolates of S. aureus, S. epidermidis, S. pyogenes, and S. faecalis and...
| Schlagworte: | DL-8280, WP0405,... |
| Anwendung: | Antibacterial antibiotic, DNA gyrase / topoisomerase IV inhibitor |
| CAS | 82419-36-1 |
| MW: | 361.4 D |
ab 43,00 €
Nadifloxacin
Artikelnummer: Cay20252-50
Nadifloxacin is a fluoroquinolone antibiotic. It is active against clinical isolates of S. aureus, coagulase-negative staphylococci, P. acnes, and P. granulosum (MIC50s = 0.03, 0.06, 0.25, and 0.125 mg/L, respectively). Nadifloxacin inhibits the activities of DNA gyrase and topoisomerase IV (IC50s = 8.83 and 3.22...
| Schlagworte: | OPC 7251, 9-fluoro-6,7-dihydro-8-(4-hydroxy-1-piperidinyl)-5-methyl-1-oxo-1H,5H-benzo[ij]quinolizine-2-carboxylic acid |
| Anwendung: | Fluoroquinolone antibiotic |
| CAS | 124858-35-1 |
| MW: | 360.4 D |
ab 43,00 €
Gemifloxacin (mesylate)
Artikelnummer: Cay21047-5
Gemifloxacin is a fluoroquinolone antibiotic that is effective against C. pneumoniae and M. tuberculosis (MIC50s = 0.25 and 8 µg/ml, respectively). Quinolones, including gemifloxacin, inhibit bacterial DNA gyrase and other topoisomerases. Formulations containing gemifloxacin are useful against respiratory tract...
| Schlagworte: | LB 20304a, SB 265805S,... |
| Anwendung: | Antibiotic, Antibacterial, Nucleic acid biosynthesis inhibitor, Topoisomerase inhibitor |
| CAS | 210353-53-0 |
| MW: | 485.5 D |
ab 50,00 €
Moxifloxacin (hydrochloride)
Artikelnummer: Cay14830-500
Moxifloxacin is a fluoroquinolone antibiotic. It is active against 390 clinical isolates of aerobic and anaerobic Gram-positive and Gram-negative bacteria (MIC90s = =0.25 µg/ml), as well as clinical isolates of methicillin-susceptible and -resistant S. aureus (MIC90s = 0.12 and 2 µg/ml, respectively). Moxifloxacin...
| Schlagworte: | BAY 12-8039,... |
| Anwendung: | Antibiotic, DNA gyrase / topoisomerase IV inhibitor |
| CAS | 186826-86-8 |
| MW: | 437.9 D |
ab 125,00 €
Clinafloxacin (hydrochloride)
Artikelnummer: Cay16923-100
Clinafloxacin is a fluoroquinolone antibiotic that displays broad-spectrum antibacterial activity against Gram-positive, Gram-negative, and anaerobic pathogens by inhibiting the bacterial regulatory enzyme DNA gyrase (IC50 = 0.92 µg/ml) as well as topoisomerase IV (IC50 = 1.62 µg/ml).Formal Name:...
| Schlagworte: | AM1091, 7-(3-amino-1-pyrrolidinyl)-8-chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid |
| Anwendung: | Antibacterial antibiotic, DNA gyrase inhibitor, Topoisomerase IV inhibitor |
| CAS | 105956-99-8 |
| MW: | 402.3 D |
ab 125,00 €
Sitafloxacin
Artikelnummer: Cay32949-5
Sitafloxacin is a fluoroquinolone antibiotic. It is active against a panel of clinical isolates from a variety of bacterial species (MIC50s = =0.006-1.56 µg/ml), including methicillin-resistant strains of S. aureus and S. epidermidis and ofloxacin-resistant P. aeruginosa (MIC50s = 0.025-6.25 µg/ml). Sitafloxacin...
| Schlagworte: | DU-6859, DU6859a,... |
| Anwendung: | Fluoroquinolone antibiotic, Antibacterial, Nucleic acid biosynthesis inhibitor |
| CAS | 127254-12-0 |
| MW: | 409.8 D |
ab 163,00 €
Orbifloxacin
Artikelnummer: Cay17353-250
Orbifloxacin is a fluoroquinolone antibiotic used in animals, including dogs, cattle, and swine, to combat gastrointestinal and respiratory infections. It is effective against most Gram-negative bacteria, including Enterobacteriaceae and Pseudomonas, with lower activity against Gram-positive aerobes.Formal Name:...
| Schlagworte: | CP 104,354, 1-cyclopropyl-7-[(3R,5S)-3,5-dimethyl-1-piperazinyl]-5,6,8-trifluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid |
| Anwendung: | Fluoroquinolone antibiotic, DNA gyrase inhibitor, Topoisomerase IV inhibitor |
| CAS | 113617-63-3 |
| MW: | 395.4 D |
ab 60,00 €
Enrofloxacin
Artikelnummer: Cay20301-5
Enrofloxacin is a fluoroquinolone antibiotic. It is active against panels of Campylobacter, E. coli, and Salmonella isolates (mean MIC50s = 0.06, 0.5, and 0.03 µg/ml, respectively). It is also active against equine isolates of L. intracellularis (MICs = 0.125-0.5 µg/ml). Enrofloxacin inhibits bacterial DNA gyrase....
| Schlagworte: | BAY-Vp 2674, ENR, PD 160788, 1-cyclopropyl-7-(4-ethyl-1-piperazinyl)-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid |
| Anwendung: | Antibacterial antibiotic, DNA gyrase / topoisomerase IV inhibitor |
| CAS | 93106-60-6 |
| MW: | 359.4 D |
ab 43,00 €
Sparfloxacin
Artikelnummer: LKT-S6000.1
A fluoroquniolone antibacterial, acts on DNA gyrase.
| Schlagworte: | SPFX |
| Anwendung: | Antibacterial agent, Topoisomerase IV inhibitor |
| CAS | 110871-86-8 |
| MW: | 392,4 D |
ab 67,00 €