Zu "K02621" wurden 33 Artikel gefunden!
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Topoisomerase IV inhibitor 1
Artikelnummer: TGM-T72153-100mg
Description: Topoisomerase IV inhibitor 2 (compound 7d) is a potent inhibitor of DNA topoisomerase IV (TOPO IV), exhibiting IC50 values of 0.23 µM for TOPO IV and 0.43 µM for DNA gyrase. It demonstrates antibacterial efficacy, with minimum inhibitory concentrations (MICs) of 0.972 µM against Staphylococcus aureus...
| Anwendung: | Topoisomerase IV inhibitor |
| CAS | 2883403-42-5 |
| MW: | 685.72 D |
ab 1.491,00 €
Topoisomerase IV inhibitor 2
Artikelnummer: TGM-T72154-100mg
Description: Topoisomerase IV inhibitor 2 (compound 5d) is a potent inhibitor of DNA topoisomerase IV (TOPO IV), exhibiting IC50 values of 0.35 µM for TOPO IV and 0.55 µM for DNA gyrase. It demonstrates antibacterial properties with minimum inhibitory concentrations (MICs) of 1.985 µM against Staphylococcus aureus...
| Anwendung: | Topoisomerase IV inhibitor |
| CAS | 2883403-36-7 |
| MW: | 671.7 D |
ab 1.491,00 €
Clinafloxacin
Artikelnummer: TGM-T1283-100mg
Description: Clinafloxacin (CI-960)(PD-127391) is a fluoroquinolone antibiotic. Target: Antibiotic, Antibacterial. Smiles: ClC1=C2N(C=C(C(O)=O)C(=O)C2=CC(F)=C1N3CC(N)CC3)C4CC4. References: Humphrey GH, et al. J Clin Pharmacol, 1999, 39(11), 1143-1150.
| Schlagworte: | AM-1091, PD 127391, CI-960 |
| Anwendung: | Topoisomerase IV inhibitor |
| CAS | 105956-97-6 |
| MW: | 365.79 D |
ab 31,00 €
Moxifloxacin (hydrochloride)
Artikelnummer: Cay14830-50
Moxifloxacin is a fluoroquinolone antibiotic. It is active against 390 clinical isolates of aerobic and anaerobic Gram-positive and Gram-negative bacteria (MIC90s = =0.25 µg/ml), as well as clinical isolates of methicillin-susceptible and -resistant S. aureus (MIC90s = 0.12 and 2 µg/ml, respectively). Moxifloxacin...
| Schlagworte: | BAY 12-8039,... |
| Anwendung: | Antibiotic, DNA gyrase / topoisomerase IV inhibitor |
| CAS | 186826-86-8 |
| MW: | 437.9 D |
ab 125,00 €
Clinafloxacin hydrochloride
Artikelnummer: LKT-C4535.250
Clinafloxacin hydrochloride is an antimicrobial fluoroquinolone which inhibits topoisomerase IV.
| Schlagworte: | AM-1091, CI-960, PD-12739 |
| Anwendung: | Topoisomerase IV inhibitor |
| CAS | 105956-97-6 |
| MW: | 402,24 D |
ab 242,00 €
Besifloxacin (hydrochloride)
Artikelnummer: Cay23692-5
Besifloxacin is an ophthalmologic fluoroquinolone antibiotic that is active against Gram-negative and Gram-positive aerobic and anaerobic bacterial strains (MICs = 0.006-1.56 µg/ml). It inhibits LPS-stimulated production of the inflammatory cytokines IL-1beta, IL-8, IL-6, and IL-1alpha in human THP-1 monocytes....
| Schlagworte: | BOL-303224-A,... |
| Anwendung: | Antibiotic, Antibacterial, Nucleic acid biosynthesis inhibitor |
| CAS | 405165-61-9 |
| MW: | 430.3 D |
ab 60,00 €
Enrofloxacin
Artikelnummer: Cay20301-25
Enrofloxacin is a fluoroquinolone antibiotic. It is active against panels of Campylobacter, E. coli, and Salmonella isolates (mean MIC50s = 0.06, 0.5, and 0.03 µg/ml, respectively). It is also active against equine isolates of L. intracellularis (MICs = 0.125-0.5 µg/ml). Enrofloxacin inhibits bacterial DNA gyrase....
| Schlagworte: | BAY-Vp 2674, ENR, PD 160788, 1-cyclopropyl-7-(4-ethyl-1-piperazinyl)-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid |
| Anwendung: | Antibacterial antibiotic, DNA gyrase / topoisomerase IV inhibitor |
| CAS | 93106-60-6 |
| MW: | 359.4 D |
ab 43,00 €
Balofloxacin
Artikelnummer: Cay25504-500
Balofloxacin is a fluoroquinolone antibiotic. It is active against clinical isolates of a variety of Gram-positive and Gram-negative bacteria in vitro, including K. pneumoniae, H. influenzae, N. gonorrhoeae, P. mirabilis, S. pyogenes, and methicillin-resistant S. aureus (MRSA, MIC50s = 0.025-0.78 µg/ml)....
| Schlagworte: | Q-35, 1-cyclopropyl-6-fluoro-1,4-dihydro-8-methoxy-7-[3-(methylamino)-1-piperidinyl]-4-oxo-3-quinolinecarboxylic acid |
| Anwendung: | Antibacterial, nucleic acid biosynthesis inhibitor, topoisomerase IV inhibitor, DNA gyrase inhibitor |
| CAS | 127294-70-6 |
| MW: | 389.4 D |
ab 50,00 €
Garenoxacin
Artikelnummer: Cay33599-5
Garenoxacin is a quinolone antibiotic. It is active against a variety of Gram-positive and Gram-negative bacteria (MIC90s = 0.025-6.25 and 0.0125-100 µg/ml, respectively). Garenoxacin inhibits E. coli DNA gyrase supercoiling and S. aureus topoisomerase IV decatenation activities (IC50s = 0.17 and 2.19 mg/L,...
| Schlagworte: | BMS-284756, T-3811ME,... |
| Anwendung: | Quinolone antibiotic, Antibacterial, Nucleic acid biosynthesis inhibitor |
| CAS | 194804-75-6 |
| MW: | 426.4 D |
ab 147,00 €
Orbifloxacin
Artikelnummer: Cay17353-100
Orbifloxacin is a fluoroquinolone antibiotic used in animals, including dogs, cattle, and swine, to combat gastrointestinal and respiratory infections. It is effective against most Gram-negative bacteria, including Enterobacteriaceae and Pseudomonas, with lower activity against Gram-positive aerobes.Formal Name:...
| Schlagworte: | CP 104,354, 1-cyclopropyl-7-[(3R,5S)-3,5-dimethyl-1-piperazinyl]-5,6,8-trifluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid |
| Anwendung: | Fluoroquinolone antibiotic, DNA gyrase inhibitor, Topoisomerase IV inhibitor |
| CAS | 113617-63-3 |
| MW: | 395.4 D |
ab 60,00 €
Nalidixic Acid
Artikelnummer: Cay19807-100
Nalidixic acid is a quinolone antibiotic. It is active against E. coli, Pasturella, K. pneumoniae, A. aerogenes, Proteus, Salmonella, and Shigella with minimum bacteriostatic concentrations (MBCs) ranging from 0.5 to 25 µg/ml. Nalidixic acid increases survival in mouse models of systemic K. pneumoniae, A. aerogenes,...
| Schlagworte: | NSC 82174, WIN 18,320, 1-ethyl-7-methyl-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid |
| Anwendung: | Antibiotic, DNA gyrase / topoisomerase IV inhibitor |
| CAS | 389-08-2 |
| MW: | 232.2 D |
ab 43,00 €
Nadifloxacin
Artikelnummer: Cay20252-500
Nadifloxacin is a fluoroquinolone antibiotic. It is active against clinical isolates of S. aureus, coagulase-negative staphylococci, P. acnes, and P. granulosum (MIC50s = 0.03, 0.06, 0.25, and 0.125 mg/L, respectively). Nadifloxacin inhibits the activities of DNA gyrase and topoisomerase IV (IC50s = 8.83 and 3.22...
| Schlagworte: | OPC 7251, 9-fluoro-6,7-dihydro-8-(4-hydroxy-1-piperidinyl)-5-methyl-1-oxo-1H,5H-benzo[ij]quinolizine-2-carboxylic acid |
| Anwendung: | Fluoroquinolone antibiotic |
| CAS | 124858-35-1 |
| MW: | 360.4 D |
ab 43,00 €