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Novobiocin
Novobiocin

Artikelnummer: TGM-T20510-100mg

Description: Novobiocin is an orally active and potent antibiotic.Novobiocin is a DNA gyrase inhibitor and heat shock protein 90 (Hsp90) antagonist with inhibitory effects on gyrase and Hsp90. Novobiocin has anti-positive activity and can be used to study highly resistant pneumococcal infections. Target: Antibiotic,...
Schlagworte: Cathomycin, Albamycin, U-6391, U6391, U 6391
Anwendung: DNA gyrase inhibitor screening
CAS 303-81-1
MW: 612.62 D
ab 31,00 €
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Tosufloxacin tosylate
Tosufloxacin tosylate

Artikelnummer: TGM-T26368-500mg

Description: Tosufloxacin is a fluoroquinolone antibiotic used to treat susceptible infections. Target: Others. Smiles: Cc1ccc(cc1)S(O)(=O)=O.NC1CCN(C1)c1nc2n(cc(C(O)=O)c(=O)c2cc1F)-c1ccc(F)cc1F. References: Kim YD, Kim MK, Wee WR, Choi HJ. Tosufloxacin deposits in compromised corneas. Optom Vis Sci. 2014...
Schlagworte: T3262, T 3262, T-3262, Tosufloxacin
Anwendung: Antibacterial antibiotic
CAS 115964-29-9
MW: 576.54 D
210,00 €
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Dihydronovobiocin
Dihydronovobiocin

Artikelnummer: TGM-T37721-5mg

Description: Dihydronovobiocin is a coumarin antibiotic and derivative of novobiocin .1It is active against the bacteriaS. aureus,S. haemolyticus,D. pneumoniae,S. typhosa,K. pneumoniae, andP. multocida(MICs = 0.6, 2, 0.6, 10, 10, and 3 µg/ml, respectively).2Dihydronovobiocin inhibits DNA gyrase subunit B with an...
Anwendung: Coumarin antibiotic, DNA gyrase subunit B inhibitor
CAS 29826-16-2
MW: 614.64 D
1.943,00 €
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Type II topoisomerase inhibitor 1
Type II topoisomerase inhibitor 1

Artikelnummer: TGM-T61054-100mg

Description: Type II topoisomerase inhibitor 1 is a potent and selective inhibitor of E. coli DNA gyrase with an IC50 value of 1.7 nM and forms hydrogen bonds with the Asp73 residue. It inhibits topoisomerase IV activity with an IC50 value of 0.98 µM and is applicable in the antibacterial area [1] [2]. Target:...
Anwendung: Type II topoisomerase inhibitor
CAS 2245691-60-3
MW: 337.33 D
ab 1.491,00 €
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GyrB Protein, Salmonella typhi, Recombinant (His & Myc)
GyrB Protein, Salmonella typhi, Recombinant (His & Myc)

Artikelnummer: TGM-TMPH-03470-100ug

Description: GyrB Protein, Salmonella typhi, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 51.8 kDa and the accession number is P0A2I4.
Schlagworte: gyrB, DNA gyrase subunit B
MW: 51.8 kD
ab 352,00 €
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Norfloxacin-d5
Norfloxacin-d5

Artikelnummer: TGM-TMIH-0398-1mg

Description: Norfloxacin-d5 is a deuterated compound of Norfloxacin. Smiles: [2H]C([2H])([2H])C([2H])([2H])N1C=C(C(O)=O)C(=O)C2=CC(F)=C(C=C12)N1CCNCC1
Anwendung: GC-MS, LC-MS, internal standard, quantification, antibacterial, topoisomerase IV inhibitor
CAS 1015856-57-1
MW: 324.36 D
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Sarafloxacin-d8 Hydrochloride
Sarafloxacin-d8 Hydrochloride

Artikelnummer: TGM-TMIJ-0037-1mg

Description: Sarafloxacin-d8 Hydrochloride is a deuterated compound of Sarafloxacin Hydrochloride. Sarafloxacin Hydrochloride has a CAS number of 91296-87-6. Sarafloxacin hydrochloride, a quinolone antibiotic drug, is a hydrochloride salt form of sarafloxacin. Smiles:...
Anwendung: GC-MS, LC-MS internal standard, quantification, antibacterial nucleic acid biosynthesis inhibitor
CAS 2733145-07-6
MW: 429.87 D
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(R)-Ofloxacin
(R)-Ofloxacin

Artikelnummer: TGM-T17307-10mg

Description: (R)-Ofloxacin is a R-isomer of Ofloxacin, an antibiotic used to treat a number of bacterial infections. Target: Others. Smiles: O=C1C=2C3=C(C(=C(F)C2)N4CCN(C)CC4)OC[C@@H](C)N3C=C1C(O)=O. References: Lahouidak S, Soriano ML, Salghi R, Zougagh M, Ríos Á. Graphene quantum dots for enhancement of...
Schlagworte: (R)-(+)-Ofloxacin, (+)-Ofloxacin, DR 3354, DR3354, D-Ofloxacin, DR-3354
Anwendung: Fluoroquinolone antibiotic, DNA gyrase inhibitor
CAS 100986-86-5
MW: 361.37 D
ab 166,00 €
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DNA gyrase subunit B (gyrB), partial, Salmonella typhi, recombinant
DNA gyrase subunit B (gyrB), partial, Salmonella typhi,...

Artikelnummer: CSB-EP358232SWW.1

Organism: Salmonella typhi. Source: E.coli. Expression Region: 415-804aa. Protein Length: partial. Tag Info: N-terminal 10xHis-tagged and C-terminal Myc-tagged. Target Protein Sequence: PALSELYLVE GDSAGGSAKQ GRNRKNQAIL PLKGKILNVE KARFDKMLSS QEVATLITAL GCGIGRDEYN PDKLRYHSII IMTDADVDGS HIRTLLLTFF YRQMPEIVER GHVYIAQPPL...
Schlagworte: STY3943, DNA gyrase subunit B, Recombinant Salmonella typhi DNA gyrase subunit B (gyrB), partial
Anwendung: Activity not tested
Exprimiert in: E.coli
Ursprungsart: Salmonella typhi
MW: 51.8 kD
ab 354,00 €
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Ciprofloxacin (hydrochloride hydrate)
Ciprofloxacin (hydrochloride hydrate)

Artikelnummer: Cay14286-5

Ciprofloxacin is a fluoroquinolone antibiotic. It is active against a variety of Gram-positive and Gram-negative bacteria in vitro, including S. aureus, L. monocytogenes, P. aeruginosa, Legionella, N. gonorrhoeae, and H. pylori (MIC50s = 0.004-1 µg/ml). It is also active against clinical isolates of Bacteroides,...
Schlagworte: BAY-o 9867, NSC 620634, 1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid,...
Anwendung: Antibiotic
CAS 86393-32-0
MW: 367.8 D
ab 43,00 €
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Novobiocin (sodium salt)
Novobiocin (sodium salt)

Artikelnummer: Cay18457-1

Bacterial DNA gyrase is a heterodimeric type II topoisomerase that negatively supercoils circular double-stranded DNA. Novobiocin is a coumarin antibiotic, first isolated from Streptomyces species, that inhibits the ATPase activity of DNA gyrase. Its antibacterial activity arises from competitive inhibition of the...
Schlagworte: NSC 2382,...
Anwendung: Bacterial DNA gyrase (GyrB) inhibitor
CAS 1476-53-5
MW: 634.6 D
ab 60,00 €
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Levofloxacin (hydrate)
Levofloxacin (hydrate)

Artikelnummer: Cay20382-1

Levofloxacin is a fluoroquinolone antibiotic and the active stereoisomer of ofloxacin (Cay-22891). It is active against S. aureus, S. epidermidis, B. subtilis, E. coli, P. aeruginosa, and K. pneumoniae (MICs = 0.25, 0.25, 0.5, 0.03, 4, and 0.25 µg/ml, respectively). Levofloxacin inhibits S. aureus DNA gyrase and...
Schlagworte: MP-376,...
Anwendung: Antibacterial, nucleic acid biosynthesis inhibitor
CAS 138199-71-0
MW: 361.4 D
ab 39,00 €
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