Zu "K02214" wurden 28 Artikel gefunden!
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Anti-CDC7
Artikelnummer: CSB-PA039310.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: CDC7. Antigen Species: Human
| Schlagworte: | Anti-CDC7, Anti-CDC7L1, Anti-huCdc7, Anti-HsCdc7, EC=2.7.11.1, Anti-CDC7-related kinase, Anti-Cell division cycle... |
| Anwendung: | ELISA, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 163,00 €
Anti-CDC7
Artikelnummer: CSB-PA099386.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: CDC7. Antigen Species: Human
| Schlagworte: | Anti-CDC7, Anti-CDC7L1, Anti-huCdc7, Anti-HsCdc7, EC=2.7.11.1, Anti-CDC7-related kinase, Anti-Cell division cycle... |
| Anwendung: | ELISA, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 163,00 €
Anti-CDC7
Artikelnummer: CSB-PA790524.100
Host Species: Rabbit. Isotype: IgG. Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by...
| Schlagworte: | Anti-CDC7, Anti-CDC7L1, Anti-huCdc7, Anti-HsCdc7, EC=2.7.11.1, Anti-CDC7-related kinase, Anti-Cell division cycle... |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
275,00 €
XL413 (hydrochloride)
Artikelnummer: Cay24906-25
XL413 is a potent inhibitor of Cdc7 (IC50 = 3.4 nM). It is >60, >10, and >300-fold selective for Cdc7 over CK2, PIM1, and a panel of over 100 protein kinases, respectively. XL413 inhibits the growth of MDA-MB-231T and COLO 205 cells (IC50s = 118 and 140 nM, respectively). It inhibits Cdc7-specific phosphorylation of...
| Schlagworte: | 8-chloro-2-(2S)-2-pyrrolidinyl-benzofuro[3,2-d]pyrimidin-4(3H)-one, monohydrochloride |
| Anwendung: | Cdc7 inhibitor |
| CAS | 2062200-97-7 |
| MW: | 326.2 D |
ab 40,00 €
PHA-767491 (hydrochloride)
Artikelnummer: Cay18218-10
Cdc7 kinase is a key regulator of the S-phase of the cell cycle. It is known to promote the activity of DNA replication origins in eukaryotic organisms. Inhibition of Cdc7 kinase causes blockade of DNA synthesis in human cell lines. Tumor cells are then funneled into the apoptotic pathway in a p53-independent...
| Schlagworte: | CAY10572, 1,5,6,7-tetrahydro-2-(4-pyridinyl)-4H-pyrrolo[3,2-c]pyridin-4-one, monohydrochloride |
| Anwendung: | Cdc7 kinase inhibitor |
| CAS | 942425-68-5 |
| MW: | 249.7 D |
ab 65,00 €
Anti-CDC7
Artikelnummer: A302-504A
Protein function: Seems to phosphorylate critical substrates that regulate the G1/S phase transition and/or DNA replication. Can phosphorylates MCM2 and MCM3. [The UniProt Consortium]
| Schlagworte: | Anti-CDC7, Anti-CDC7L1, Anti-huCdc7, Anti-HsCdc7, EC=2.7.11.1, Anti-CDC7-related kinase, Anti-Cell division cycle... |
| Anwendung: | WB, IP |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 164,00 €
Anti-CDC7
Artikelnummer: E-AB-16331.120
This gene encodes a cell division cycle protein with kinase activity that is critical for the G1/S transition. The yeast homolog is also essential for initiation of DNA replication as cell division occurs. Overexpression of this gene product may be associated with neoplastic transformation for some tumors. Multiple...
| Schlagworte: | Anti-CDC7, Anti-CDC7L1, Anti-HsCdc7, Anti-huCdc7, EC=2.7.11.1, Anti-CDC7-related kinase, Anti-Cell division cycle... |
| Anwendung: | IHC, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 71,00 €
Anti-CDC7
Artikelnummer: E-AB-13139.120
This gene encodes a cell division cycle protein with kinase activity that is critical for the G1/S transition. The yeast homolog is also essential for initiation of DNA replication as cell division occurs. Overexpression of this gene product may be associated with neoplastic transformation for some tumors. Multiple...
| Schlagworte: | Anti-CDC7, Anti-CDC7L1, Anti-HsCdc7, Anti-huCdc7, EC=2.7.11.1, Anti-CDC7-related kinase, Anti-Cell division cycle... |
| Anwendung: | IHC, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 71,00 €
LY3177833
Artikelnummer: Cay25988-10
LY3177833 is an orally bioavailable inhibitor of Cdc7 kinase (IC50 = 3.3 nM for ADP production in an enzyme assay). It inhibits phosphorylation of MCM2-S53 in H1299 cells (IC50 = 0.29 µM). LY3177833 reduces tumor growth in an SW620 human colorectal adenocarcinoma mouse xenograft model when administered at doses of...
| Schlagworte: | (3R)-3-(5-fluoro-4-pyrimidinyl)-2,3-dihydro-3-methyl-6-(1H-pyrazol-4-yl)-1H-isoindol-1-one |
| Anwendung: | Cdc7 kinase inhibitor |
| CAS | 1627696-51-8 |
| MW: | 309.3 D |
ab 125,00 €
Anti-CDC7, clone BGF-3
Artikelnummer: NSJ-RQ4689
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA. This gene encodes Cell division cycle 7-related protein kinase, a cell division cycle protein with kinase activity that is critical for the G1/S transition. The yeast homolog is also essential for initiation of DNA replication as cell...
| Schlagworte: | Anti-huCdc7, Anti-CDC7L1, Anti-HsCdc7, Anti-CDC7-related kinase, Anti-Cell division cycle 7-related protein kinase, CDC7... |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
755,00 €
Anti-CDC7
Artikelnummer: ARG41364.100
Protein function: Seems to phosphorylate critical substrates that regulate the G1/S phase transition and/or DNA replication. Can phosphorylates MCM2 and MCM3. [The UniProt Consortium]
| Schlagworte: | Anti-CDC7, Anti-CDC7L1, Anti-HsCdc7, Anti-huCdc7, EC=2.7.11.1, Anti-CDC7-related kinase, Anti-Cell division cycle... |
| Anwendung: | FC, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
624,00 €
CDC7/DBF4 Complex
Artikelnummer: BPS-100538
CDC7/DBF4 complex of human CDC7, also known as HsCDC7 and Hsk 1, GenBank Accession No. NM_003503 a.a. 1-574(end) with N-terminal GST-tag and MW= 94 kDa, and human DBF4, also known as ASK and CHIF, GenBank Accession No. NM_006716, a.a. 1-674(end) with N-terminal GST-tag and MW= 125 kDa, co-expressed expressed in an...
| Schlagworte: | CDC7: HsCDC7, Hsk 1 DBF4: ASK, CHIF, |
| Anwendung: | Enzyme kinetics, inhibitor screening, selectivity profiling |
| Exprimiert in: | insect cells |
| Ursprungsart: | human |
| MW: | 94 / 125 kD |
977,00 €