Zu "K02145" wurden 23 Artikel gefunden!
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EN6
Artikelnummer: Cay28715-5
EN6 is an activator of autophagy. It inhibits mammalian target of rapamycin complex 1 (mTORC1) signaling by binding covalently to cysteine 277 of the ATP6V1A catalytic subunit of the lysosomal vacuolar ATPase (v-ATPase) and impairing v-ATPase coupling with Rag GTPases. It is selective for inhibition of mTORC1 over...
| Schlagworte: | N-[4-fluoro-3-[(1-oxo-2-propen-1-yl)amino]phenyl]-1-(2-fluorophenyl)-1H-pyrazole-4-carboxamide |
| Anwendung: | Autophagy activator, mTORC1 inhibitor |
| CAS | 1808714-73-9 |
| MW: | 368.3 D |
ab 110,00 €
Anti-ATP6V1A
Artikelnummer: A305-193A
Protein function: Catalytic subunit of the peripheral V1 complex of vacuolar ATPase. V-ATPase vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. [The UniProt Consortium]
| Schlagworte: | Anti-ATP6A1, Anti-ATP6V1A, EC=3.6.3.14, Anti-V-ATPase subunit A, Anti-V-ATPase 69 kDa subunit, Anti-Vacuolar ATPase... |
| Anwendung: | WB, IP |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 178,00 €
Anti-ATP6V1A
Artikelnummer: A305-194A
Protein function: Catalytic subunit of the peripheral V1 complex of vacuolar ATPase. V-ATPase vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. [The UniProt Consortium]
| Schlagworte: | Anti-ATP6A1, Anti-ATP6V1A, EC=3.6.3.14, Anti-V-ATPase subunit A, Anti-V-ATPase 69 kDa subunit, Anti-Vacuolar ATPase... |
| Anwendung: | WB, IP |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 178,00 €
Bafilomycin C1
Artikelnummer: Cay19625-5
Bafilomycin C1 is a bacterial metabolite that has been found in Streptomyces and has diverse biological activities. It inhibits the activities of vacuolar H+-ATPases (V-ATPases) and Na+/K+-ATPases in a concentration-dependent manner. Bafilomycin C1 (1 mg/ml) is active against a panel of 24 fungi in a disc assay. It...
| Schlagworte: | 2-Demethyl-2-methoxy-24-methyl-hygrolidin, L-681,110A1, 2E-butenedioic... |
| Anwendung: | V-ATPase inhibitor |
| CAS | 88979-61-7 |
| MW: | 720.9 D |
ab 111,00 €
Manzamine A
Artikelnummer: LKT-M0255.10
Manzamine A is an alkaloid isolated from marine sponges. Manzamine A exhibits neuroprotective, anticancer, anti-hyperlipidemic, anti-atherosclerotic, antibiotic, and antiviral activities. In vitro, manzamine A uncouples vacuolar ATPases, inhibiting autophagy and tumor growth. Manzamine A inhibits foam cell...
| Anwendung: | Vacuolar ATPase inhibitor |
| CAS | 104196-68-1 |
| MW: | 548.76 D |
ab 1.706,00 €
Anti-ATP6V1A
Artikelnummer: ARG57716.100
Protein function: Catalytic subunit of the peripheral V1 complex of vacuolar ATPase. V-ATPase vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. In aerobic conditions, involved in intracellular iron homeostasis, thus triggering the activity of Fe(2+) prolyl...
| Schlagworte: | Anti-ATP6A1, Anti-ATP6V1A, EC=3.6.3.14, Anti-V-ATPase subunit A, Anti-V-ATPase 69 kDa subunit, Anti-Vacuolar ATPase... |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
658,00 €
Anti-ATP6V1A
Artikelnummer: ATA-HPA035083.100
Protein function: Catalytic subunit of the peripheral V1 complex of vacuolar ATPase. V-ATPase vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. In aerobic conditions, involved in intracellular iron homeostasis, thus triggering the activity of Fe(2+) prolyl...
| Schlagworte: | Anti-ATP6A1, Anti-ATP6V1A, EC=7.1.2.2, Anti-V-ATPase subunit A, Anti-V-ATPase 69 kDa subunit, Anti-Vacuolar ATPase isoform... |
| Anwendung: | ICC, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 239,00 €
Anti-ATP6V1A
Artikelnummer: ATA-HPA035084.100
Protein function: Catalytic subunit of the peripheral V1 complex of vacuolar ATPase. V-ATPase vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. In aerobic conditions, involved in intracellular iron homeostasis, thus triggering the activity of Fe(2+) prolyl...
| Schlagworte: | Anti-ATP6A1, Anti-ATP6V1A, EC=7.1.2.2, Anti-V-ATPase subunit A, Anti-V-ATPase 69 kDa subunit, Anti-Vacuolar ATPase isoform... |
| Anwendung: | ICC, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 239,00 €
Anti-ATP6V1A / V-ATPase subunit A
Artikelnummer: NSJ-RQ6823
0.5mg/ml if reconstituted with 0.2ml sterile DI water. V-type proton ATPase catalytic subunit A is an enzyme that in humans is encoded by the ATP6V1A gene. This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase...
| Schlagworte: | Anti-ATP6A1, Anti-ATP6V1A, Anti-V-ATPase subunit A, Anti-V-ATPase 69 kDa subunit, Anti-Vacuolar ATPase isoform VA68,... |
| Anwendung: | WB, IHC (paraffin), IF, FC, Direct ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
772,00 €
NEU
Anti-ATP6V1A Recombinant
Artikelnummer: ABS-RC-4429.100
Protein function: Catalytic subunit of the peripheral V1 complex of vacuolar ATPase. V-ATPase vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. In aerobic conditions, involved in intracellular iron homeostasis, thus triggering the activity of Fe(2+) prolyl...
| Schlagworte: | Anti-V-type proton ATPase catalytic subunit A, Anti-V-ATPase subunit A, Anti-V-ATPase 69 kDa subunit, Anti-Vacuolar ATPase... |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 232,00 €
NEU
Anti-ATP6V1A Recombinant
Artikelnummer: ABS-RC-5623.100
Protein function: Catalytic subunit of the peripheral V1 complex of vacuolar ATPase. V-ATPase vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. In aerobic conditions, involved in intracellular iron homeostasis, thus triggering the activity of Fe(2+) prolyl...
| Schlagworte: | Anti-V-type proton ATPase catalytic subunit A, Anti-V-ATPase subunit A, Anti-V-ATPase 69 kDa subunit, Anti-Vacuolar ATPase... |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 232,00 €
Anti-ATP6V1A
Artikelnummer: CSB-PA002396GA01HU.100
Host Species: Rabbit. Isotype: IgG. Buffer: PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen Affinity Purified. Target Name: ATP6V1A. Antigen Species: Human
| Schlagworte: | Anti-ATP6A1, Anti-ATP6V1A, EC=7.1.2.2, Anti-V-ATPase subunit A, Anti-V-ATPase 69 kDa subunit, Anti-Vacuolar ATPase isoform... |
| Anwendung: | ELISA, WB, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
552,00 €