Zu "K02105" wurden 298 Artikel gefunden!
Für die Filterung wurden keine Ergebnisse gefunden!
NEU
Anti-CTNNB1
Artikelnummer: ABS-KC-6240.100
Protein function: Key downstream component of the canonical Wnt signaling pathway (PubMed:17524503, PubMed:18077326, PubMed:18086858, PubMed:18957423, PubMed:21262353, PubMed:22155184, PubMed:22647378, PubMed:22699938). In the absence of Wnt, forms a complex with AXIN1, AXIN2, APC, CSNK1A1 and GSK3B that promotes...
| Schlagworte: | Anti-Catenin beta-1, Anti-Beta-catenin, CTNNB1 Antibody |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human, mouse, rat |
ab 232,00 €
CCT 031374 hydrobromide
Artikelnummer: TGM-T21685-1mg
Description: CCT 031374 hydrobromide is a TCF/beta-catenin inhibitor with antitumor activities. Target: Wnt/beta-catenin. Smiles: Br.O=C(CN1C2=NCCN2C2=C1C=CC=C2)C1=CC=C(C=C1)C1=CC=CC=C1. References: Ewan K, et al. A useful approach to identify novel small-molecule inhibitors of Wnt-dependent transcription. Cancer...
| Anwendung: | beta-Catenin/TCF complex signaling inhibitor |
| CAS | 1219184-91-4 |
| MW: | 434.33 D |
ab 68,00 €
iCRT 14
Artikelnummer: TGM-T4486-100mg
Description: iCRT 14 is a novel and potent inhibitor of beta-catenin-responsive transcription (CRT) with an IC50 of 40.3 nM in assays of Wnt pathway activity. Target: Wnt/beta-catenin. Smiles: Cc1cc(C=C2SC(=O)N(C2=O)c2ccccc2)c(C)n1-c1cccnc1. References: Gonsalves FC, et al. An RNAi-based chemical genetic screen...
| Anwendung: | beta-catenin inhibitor |
| CAS | 677331-12-3 |
| MW: | 375.44 D |
ab 31,00 €
ICG-001
Artikelnummer: TGM-T6113-100mg
Description: ICG-001 antagonizes Wnt/beta-catenin/TCF-mediated transcription and specifically binds to element-binding protein (CBP) with IC50 of 3 µM, but is not the related transcriptional coactivator p300. Target: Epigenetic Reader Domain, Apoptosis, Wnt/beta-catenin. Smiles:...
| Anwendung: | beta-catenin / CBP inhibitor |
| CAS | 780757-88-2 |
| MW: | 548.63 D |
ab 31,00 €
PNU-74654
Artikelnummer: TGM-T7204-100mg
Description: PNU 74654 binds to beta-catenin (Kd = 450 nM), inhibiting its interaction with the transcription factor T cell factor 4 (Tcf4) resulting in disruption of the Wnt signaling pathway. Target: Apoptosis, Wnt/beta-catenin. Smiles: Cc1ccc(\C=N\NC(=O)c2ccccc2Oc2ccccc2)o1. References: Leal, Letícia F, Bueno A...
| Anwendung: | Tcf4/beta-catenin interaction inhibitor |
| CAS | 113906-27-7 |
| MW: | 320.34 D |
ab 52,00 €
MSAB
Artikelnummer: TGM-T8710-100mg
Description: MSAB is a selective inhibitor of Wnt/beta-catenin signaling. MSAB binds to beta-catenin, promoting its degradation, and specifically downregulates Wnt/beta-catenin target genes. Target: Wnt/beta-catenin. Smiles: COC(=O)c1cccc(NS(=O)(=O)c2ccc(C)cc2)c1. References: Hwang SY, et, al. Direct Targeting of...
| Anwendung: | Wnt/beta-catenin signaling inhibitor |
| CAS | 173436-66-3 |
| MW: | 305.35 D |
ab 31,00 €
Beta-Catenin Protein, Human, Recombinant (His & GST)
Artikelnummer: TGM-TMPY-02205-100ug
Description: Beta-Catenin Protein, Human, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 113 kDa and the accession number is P35222-1.
| Schlagworte: | armadillo, catenin beta 1, MRD19, catenin beta1, CTNNB, beta-Catenin |
| MW: | 113 kD |
ab 386,00 €
Beta-Catenin Protein, Mouse, Recombinant (His & GST)
Artikelnummer: TGM-TMPY-02985-20ug
Description: Beta-Catenin Protein, Mouse, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 113 kDa and the accession number is Q02248.
| Schlagworte: | Catnb, beta-Catenin, Bfc, catenin beta1, catenin beta 1, Mesc |
| MW: | 113 kD |
356,00 €
PRI-724
Artikelnummer: TGM-T64414-100mg
Description: PRI-724 (C-82 prodrug) is a selective small-molecule inhibitor of beta-catenin/CBP interaction. Target: Wnt/beta-catenin. Smiles: C([C@@H]1N2[C@@](N(C(NCC3=CC=CC=C3)=O)N(C)CC2=O)([C@H](C)N(CC=4C5=C(C=CC4)C=CC=N5)C1=O)[H])C6=CC=C(OP(=O)(O)O)C=C6. References: PRI-724 reduces liver fibrosis, and hepatic...
| Schlagworte: | Foscenvivint, ICG-001 analog, C-82 prodrug |
| Anwendung: | Targets catenin beta 1 (CTNNB1) |
| CAS | 1422253-38-0 |
| MW: | 658.64 D |
ab 42,00 €
Catenin beta-1 (CTNNB1), human, recombinant
Artikelnummer: CSB-EP006169HU.1
Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 2-781aa. Protein Length: Full Length of Mature Protein. Tag Info: N-terminal GST-tagged. Target Protein Sequence: ATQADLMELD MAMEPDRKAA VSHWQQQSYL DSGIHSGATT TAPSLSGKGN PEEEDVDTSQ VLYEWEQGFS QSFTQEQVAD IDGQYAMTRA QRVRAAMFPE TLDEGMQIPS TQFDAAHPTN...
| Schlagworte: | CTNNB, CTNNB1, Beta-catenin, Catenin beta-1, Recombinant Human Catenin beta-1 (CTNNB1) |
| Anwendung: | Activity not tested |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 112.4 kD |
ab 219,00 €
Catenin beta-1 (CTNNB1), human, recombinant
Artikelnummer: CSB-EP006169HUa0.1
Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 2-781aa. Protein Length: Full Length of Mature Protein. Tag Info: N-terminal 6xHis-tagged. Target Protein Sequence: ATQADLMELD MAMEPDRKAA VSHWQQQSYL DSGIHSGATT TAPSLSGKGN PEEEDVDTSQ VLYEWEQGFS QSFTQEQVAD IDGQYAMTRA QRVRAAMFPE TLDEGMQIPS TQFDAAHPTN...
| Schlagworte: | CTNNB, CTNNB1, Beta-catenin, Catenin beta-1, Recombinant Human Catenin beta-1 (CTNNB1) |
| Anwendung: | Activity not tested |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 90.9 kD |
ab 219,00 €