Zu "K02090" wurden 68 Artikel gefunden!
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NEU
Cyclin-dependent kinase 5 (CDK5), human, recombinant
Artikelnummer: CSB-EP005067HU.1
Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 1-292aa. Protein Length: Full Length. Tag Info: N-terminal 6xHis-SUMO-tagged. Target Protein Sequence: MQKYEKLEKI GEGTYGTVFK AKNRETHEIV ALKRVRLDDD DEGVPSSALR EICLLKELKH KNIVRLHDVL HSDKKLTLVF EFCDQDLKKY FDSCNGDLDP EIVKSFLFQL LKGLGFCHSR NVLHRDLKPQ...
| Schlagworte: | CDK5, CDKN5, EC=2.7.11.1, TPKII catalytic subunit, Cell division protein kinase 5, Cyclin-dependent-like kinase 5, Tau... |
| Anwendung: | Activity not tested |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 49.3 kD |
ab 213,00 €
NEU
Cyclin-dependent kinase 5 (CDK5), human, recombinant
Artikelnummer: CSB-EP005067HUb0.1
Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 1-292aa. Protein Length: Full Length. Tag Info: N-terminal 10xHis-tagged. Target Protein Sequence: MQKYEKLEKI GEGTYGTVFK AKNRETHEIV ALKRVRLDDD DEGVPSSALR EICLLKELKH KNIVRLHDVL HSDKKLTLVF EFCDQDLKKY FDSCNGDLDP EIVKSFLFQL LKGLGFCHSR NVLHRDLKPQ...
| Schlagworte: | CDK5, CDKN5, EC=2.7.11.1, TPKII catalytic subunit, Cell division protein kinase 5, Cyclin-dependent-like kinase 5, Tau... |
| Anwendung: | Activity not tested |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 39.3 kD |
ab 213,00 €
NEU
Cyclin-dependent kinase 5 (CDK5), human, recombinant
Artikelnummer: CSB-EP005067HUe1.1
Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 1-292aa. Protein Length: Full Length. Tag Info: Tag-Free. Target Protein Sequence: MQKYEKLEKI GEGTYGTVFK AKNRETHEIV ALKRVRLDDD DEGVPSSALR EICLLKELKH KNIVRLHDVL HSDKKLTLVF EFCDQDLKKY FDSCNGDLDP EIVKSFLFQL LKGLGFCHSR NVLHRDLKPQ NLLINRNGEL KLADFGLARA...
| Schlagworte: | CDK5, CDKN5, EC=2.7.11.1, TPKII catalytic subunit, Cell division protein kinase 5, Cyclin-dependent-like kinase 5, Tau... |
| Anwendung: | Activity not tested |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 33.4 kD |
ab 355,00 €
Indirubin
Artikelnummer: LKT-I5212.5
Indirubin is a bisindole isomer of indigo, naturally sourced from Indigo naturalis. Indirubin exhibits anti-inflammatory, anti-angiogenic, and anticancer chemotherapeutic activities. In vivo, indirubin decreases levels of IgE and production of inflammatory cytokines, decreasing overall inflammation as well as skin...
| Anwendung: | CDK inhibitor |
| CAS | 479-41-4 |
| MW: | 262.26 D |
ab 104,00 €
Mouse CDK5 (Cyclin Dependent Kinase 5) ELISA Kit
Artikelnummer: ELK-ELK7636.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Mouse CDK5. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Mouse CDK5. Next,...
| Schlagworte: | EC=2.7.11.1, TPKII catalytic subunit, Cyclin-dependent kinase 5, Cell division protein kinase 5, Cyclin-dependent-like... |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | mouse |
ab 365,00 €
Human CDK5 (Cyclin Dependent Kinase 5) ELISA Kit
Artikelnummer: ELK-ELK2095.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human CDK5. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human CDK5. Next,...
| Schlagworte: | EC=2.7.11.1, TPKII catalytic subunit, Cyclin-dependent kinase 5, Cell division protein kinase 5, Cyclin-dependent-like... |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
ab 365,00 €
Rat CDK5 (Cyclin Dependent Kinase 5) ELISA Kit
Artikelnummer: ELK-ELK4419.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Rat CDK5. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Rat CDK5. Next,...
| Schlagworte: | EC=2.7.11.1, TPKII catalytic subunit, Cyclin-dependent kinase 5, Cell division protein kinase 5, Cyclin-dependent-like... |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | rat |
ab 365,00 €
Dinaciclib
Artikelnummer: Cay14707-5
Cyclin-dependent kinases (CDKs) are critical positive regulators of cell cycle progression and cellular transcription whose dysregulation can lead to the development of cancer. Dinaciclib inhibits CDK1, CDK2, CDK5, and CDK9 activity in vitro with IC50 values of 3, 1, 1, and 4 nM, respectively. Compared to the...
| Schlagworte: | SCH 727965, 1-[3-ethyl-7-[[(1-oxido-3-pyridinyl)methyl]amino]pyrazolo[1,5-a]pyrimidin-5-yl]-2S-piperidineethanol |
| Anwendung: | CDK1 / CDK2 / CDK5 / CDK9 inhibitor |
| CAS | 779353-01-4 |
| MW: | 396.5 D |
ab 125,00 €
SR 1664
Artikelnummer: Cay11086-10
Apart from direct peroxisome proliferator-activated receptor gamma (PPARgamma) agonism, several PPARgamma ligands have recently been shown to exert anti-diabetic effects through a second, distinct biochemical function: blocking the obesity-linked phosphorylation of PPARgamma by cyclin-dependent kinase 5 (Cdk5) at...
| Schlagworte: | 4'-[[2,3-dimethyl-5-[[[(1S)-1-(4-nitrophenyl)ethyl]amino]carbonyl]-1H-indol-1-yl]methyl]-[1,1'-biphenyl]-2-carboxylic acid |
| Anwendung: | Blocks phosphorylation of PPARgamma by Cdk5 |
| CAS | 1338259-05-4 |
| MW: | 547.6 D |
ab 61,00 €
Butyrolactone I
Artikelnummer: BVT-0448-M005
White to off-white solid. Soluble in DMSO, methanol, ethanol or acetone. Isolated from Aspergillus terreus. Cell permeable, potent and selective cyclin-dependent kinase CDK-1 (CDC2), -2 and -5 inhibitor. Apoptosis inducer. Antitumor agent. Inhibits cell cycle progression at the G1/S and G2/M transitions. Shown to...
| Anwendung: | Cell permeable CDK-1, -2, -5 inhibitor, Apoptosis inducer |
| CAS | 87414-49-1 |
| MW: | 424.5 D |
ab 100,00 €
PHA-793887
Artikelnummer: Cay18388-5
PHA-793887 is an inhibitor of cyclin-dependent kinases (CDKs, IC50s = 8, 8, 5, and 10 nM for Cdk2/cyclin A, Cdk2/cyclin E, Cdk5/p25, and Cdk7/cyclin H, respectively). It is selective for these CDKs over Cdk1/cyclin B, Cdk4/cyclin D1, Cdk9/cyclin T1, and glycogen synthase kinase 3beta (GSK3beta, IC50s = 60, 62, 138,...
| Schlagworte: | 3-methyl-N-[1,4,5,6-tetrahydro-6,6-dimethyl-5-[(1-methyl-4-piperidinyl)carbonyl]pyrrolo[3,4-c]pyrazol-3-yl]-butanamide |
| Anwendung: | CDK2, CDK5, CDK7 inhibitor |
| CAS | 718630-59-2 |
| MW: | 361.5 D |
ab 62,00 €
Cdk1/5 Inhibitor
Artikelnummer: Cay18740-1
Cyclin-dependent kinases (Cdks) are key regulators of cell cycle progression and are therefore promising targets for cancer therapy. Cdk1/5 Inhibitor is a pyrazolo [3,4-b] quioxaline that inhibits Cdk1/cyclin B and Cdk5/p25 (IC50s = 600 and 400 nM, respectively). It less potently inhibits GSK3beta (IC50 = 1 µM) and...
| Schlagworte: | Cyclin-dependent kinase 1/5 Inhibitor, NSC 693868, 1H-pyrazolo[3,4-b]quinoxalin-3-amine |
| Anwendung: | Cdk1/cyclin B inhibitor, Cdk5/p25 inhibitor |
| CAS | 40254-90-8 |
| MW: | 185.2 D |
ab 66,00 €