Zu "K02087" wurden 204 Artikel gefunden!
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6-(Dimethylamino)purine
Artikelnummer: TGM-T7444-100mg
Description: 6-(Dimethylamino)purine (N,N-Dimethyladenine) is a serine threonine protein kinase and CDK inhibitor. Target: Serine/threonin kinase, CDK. Smiles: CN(C)c1ncnc2nc[nH]c12. References: Nakashima M , Cui Z G , Tabuchi Y , et al. Apoptosis induced by an alkylated purine, 6-dimethylaminopurine, and changes...
| Schlagworte: | N,N-Dimethyladenine |
| Anwendung: | Protein kinase inhibitor |
| CAS | 938-55-6 |
| MW: | 163.18 D |
30,00 €
ALSTERPAULLONE
Artikelnummer: TGM-T7426-100mg
Description: Alsterpaullone is a Cyclin-Dependent Kinase Inhibitor, Mediated Toxicity in HeLa Cells Through Apoptosis-Inducing Effec. Target: CDK, GSK-3, Apoptosis. Smiles: [O-][N+](=O)c1ccc2[nH]c-3c(CC(=O)Nc4ccccc-34)c2c1. References: Cui C , Wang Y , Wang Y , et al. Alsterpaullone, a Cyclin-Dependent Kinase...
| Anwendung: | CDK inhibitor |
| CAS | 237430-03-4 |
| MW: | 293.28 D |
ab 87,00 €
BS194
Artikelnummer: TGM-T7698-100mg
Description: BS194 is as a potent cyclin-dependent protein kinases (CDKs) inhibitor. Target: CDK. Smiles: C(C)(C)C1=C2N(C(NCC3=CC=CC=C3)=CC(N[C@H]([C@@H](CO)O)CO)=N2)N=C1. References: Exploring the selectivity of a ligand complex with CDK2/CDK1: a molecular dynamics simulation approach[J]. Journal of Molecular...
| Anwendung: | CDK2 / CDK1 / CDK5 / CDK7 / CDK9 inhibitor |
| CAS | 1092443-55-4 |
| MW: | 385.46 D |
ab 72,00 €
CDK1 Protein, Human, Recombinant (His)
Artikelnummer: TGM-TMPH-01167-100ug
Description: CDK1 Protein, Human, Recombinant (His) is expressed in E. coli.
| Schlagworte: | Cyclin-dependent kinase 1, CDKN1, Cell division protein kinase 1, P34CDC2, CDC2, CDK1, CDC28A, Cell division control... |
| MW: | 38.1 kD |
ab 232,00 €
CDK1 Protein, Mouse, Recombinant (His & GST)
Artikelnummer: TGM-TMPY-04775-50ug
Description: CDK1 Protein, Mouse, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 61.9 kDa and the accession number is P11440.
| Schlagworte: | p34<, cyclin-dependent kinase 1, CDC2>, Cdc2, Cdc2a |
| MW: | 61.9 kD |
290,00 €
CDK1 Protein, Human, Recombinant (GST)
Artikelnummer: TGM-TMPY-04549-50ug
Description: CDK1 Protein, Human, Recombinant (GST) is expressed in Baculovirus insect cells with GST tag. The predicted molecular weight is 60 kDa and the accession number is P06493-1.
| Schlagworte: | CDC2, CDC28A, P34CDC2, cyclin-dependent kinase 1 |
| MW: | 60 kD |
290,00 €
Butyrolactone I
Artikelnummer: TGM-T25192-10mg
Description: Butyrolactone I (Olomoucin) is an ATP-competitive inhibitor of CDK and cdc2 kinase family. Butyrolactone I shows antitumor effects in non-small cell lung, small cell lung, and prostate cancer cell lines. Target: CDK. Smiles: COC(=O)[C@]1(Cc2ccc(O)c(CC=C(C)C)c2)OC(=O)C(O)=C1c1ccc(O)cc1. References:...
| Schlagworte: | Olomoucin |
| Anwendung: | Cell permeable CDK1/2/5 inhibitor, Apoptosis inducer |
| CAS | 87414-49-1 |
| MW: | 424.44 D |
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AT7519 Hydrochloride
Artikelnummer: TGM-T1778-10mg
Description: AT7519 Hydrochloride (AT7519 HCl) is a multi-CDK inhibitor for CDK1, 2, 4, 6 and 9. Target: Apoptosis, CDK, GSK-3. Smiles: Cl.Clc1cccc(Cl)c1C(=O)Nc1c[nH]nc1C(=O)NC1CCNCC1. References: Squires MS, et al. Mol Cancer Ther, 2009, 8(2), 324-332.
| Schlagworte: | AT7519 HCl, AT 7519 hydrochloride salt |
| Anwendung: | CDK inhibitor |
| CAS | 902135-91-5 |
| MW: | 418.71 D |
ab 52,00 €
CDK1-IN-2
Artikelnummer: TGM-T64373-100mg
Description: CDK1-IN-2 (cdk1 inhibitor 2) is a CDK1 inhibitor with IC50 of 5.8 µM. A broad-spectrum kinase profiling of CDK1-IN-2 revealed nonselective inhibition of several kinases. Target: CDK. Smiles: Clc1[nH]c2ccccc2c1\C=C1\C(=O)Nc2ccccc12. References: Jorda R, et al. How Selective Are Pharmacological Inhibitors...
| Schlagworte: | cdk1 inhibitor 2 |
| Anwendung: | Cyclin-dependent kinase 1 inhibitor |
| CAS | 220749-41-7 |
| MW: | 294.73 D |
ab 46,00 €
Cdk1/2 Inhibitor III
Artikelnummer: TGM-T14914-100mg
Description: Cdk1/2 Inhibitor III is a selective inhibitor of Cdk1/2 with an IC50 value of 2.1 µM against CDK1/cyclin B. Target: CDK. Smiles: C(NC1=C(F)C=CC=C1F)(=S)N2C(NC3=CC=C(S(N)(=O)=O)C=C3)=NC(N)=N2. References: Lin R, et al. Acyl-1H-[1,2,4]triazole-3,5-diamine analogues as novel and potent anticancer...
| Anwendung: | Cdk1/2 inhibitor |
| CAS | 443798-55-8 |
| MW: | 425.44 D |
ab 342,00 €
CGP60474
Artikelnummer: TGM-T14943-100mg
Description: CGP60474 is an inhibitor of VEGFR-2 (IC50 = 84 nM) and an inhibitor of ATP-competitive PKC. CGP60474 is also a highly potent anti-endotoxemic agent and inhibits cyclin-dependent kinase (CDK) potently. Target: CDK, PKC, VEGFR. Smiles: OCCCNc1cc(ccn1)-c1ccnc(Nc2cccc(Cl)c2)n1. References: Kuo GH, et al....
| Anwendung: | CDK inhibitor |
| CAS | 164658-13-3 |
| MW: | 355.82 D |
ab 31,00 €
RP-106
Artikelnummer: TGM-T24734-1mg
Description: RP-106 is an ATP-competitive inhibitor of CDK5/p25, CDK1/cyclin B, and GSK-3. Target: Others. Smiles: C(CCC)C1=C(NC=2C1=NC=CN2)C3=CC=C(OC)C=C3. References: Dong B, Chen J, Zhang X, Pan Z, Bai F, Li Y. Two novel PRP31 premessenger ribonucleic acid processing factor 31 homolog mutations including a...
| Schlagworte: | RP 106 |
| Anwendung: | CDK1/cyclin B inhibitor |
| CAS | 496864-15-4 |
| MW: | 281.35 D |
ab 81,00 €