Zu "K01852" wurden 27 Artikel gefunden!
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BIBB 515
Artikelnummer: TGM-T4039-10mg
Description: BIBB 515 is a selective and potent inhibitor of OSC in vivo with an ED50 value of 0.2-0.5 and 0.36-33.3 mg/kg in rats and mice, respectively. 2, 3-Oxidosqualene cyclase (OSC) is an important enzyme in the biosynthesis of animal, plant, and fungal sterols. OSC catalyzes the conversion of (3S)-2,...
| Anwendung: | OSC inhibitor |
| CAS | 156635-05-1 |
| MW: | 380.87 D |
ab 42,00 €
LANOSTEROL
Artikelnummer: TGM-T4970-100mg
Description: Lanosterol (3beta-Hydroxy-8,24-lanostadiene) is a tetracyclic triterpenoid which is the compound from which all steroids are derived. Target: Endogenous Metabolite. Smiles: [H][C@@]1(CC[C@@]2(C)C3=C(CC[C@]12C)[C@@]1(C)CC[C@H](O)C(C)(C)[C@]1([H])CC3)[C@H](C)CCC=C(C)C. References: Sinha R , Ahn J ,...
| Schlagworte: | 3beta-Hydroxy-8,24-lanostadiene, 8,24-Lanostadien-3beta-ol |
| Anwendung: | Naturally-occurring sterol |
| CAS | 79-63-0 |
| MW: | 426.72 D |
ab 54,00 €
Lanosterol synthase/LSS Protein, Human, Recombinant (His)
Artikelnummer: TGM-TMPH-01603-100ug
Description: Key enzyme in the cholesterol biosynthesis pathway. Catalyzes the cyclization of (S)-2,3 oxidosqualene to lanosterol, a reaction that forms the sterol nucleus. Through the production of lanosterol may regulate lens protein aggregation and increase transparency.
| Schlagworte: | LSS, Lanosterol synthase, 2,3-epoxysqualene--lanosterol cyclase, Oxidosqualene--lanosterol cyclase |
| MW: | 89.2 kD |
ab 281,00 €
U18666A
Artikelnummer: TGM-T17190-100mg
Description: U18666A is a cell-permeable drug and is a cholesterol synthesis and transport inhibitor. It inhibits replication of Ebola virus, dengue virus, and human hepatitis C virus. Target: HCV Protease, Others. Smiles: Cl.[H][C@@]12CCC(=O)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])CC=C2C[C@H](CC[C@]12C)OCCN(CC)CC....
| Anwendung: | Cholesterol transport inhibitor |
| CAS | 3039-71-2 |
| MW: | 424.06 D |
ab 40,00 €
Lanosterol synthase (LSS), human, recombinant
Artikelnummer: CSB-EP013216HU.1
Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 2-732aa. Protein Length: Full Length of Mature Protein. Tag Info: N-terminal 10xHis-tagged. Target Protein Sequence: TEGTCLRRRG GPYKTEPATD LGRWRLNCER GRQTWTYLQD ERAGREQTGL EAYALGLDTK NYFKDLPKAH TAFEGALNGM TFYVGLQAED GHWTGDYGGP LFLLPGLLIT CHVARIPLPA...
| Schlagworte: | OSC, LSS, hOSC, Lanosterol synthase, Oxidosqualene--lanosterol cyclase, 2,3-epoxysqualene--lanosterol cyclase, Recombinant... |
| Anwendung: | Activity not tested |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 89.2 kD |
ab 292,00 €
Lanosterol
Artikelnummer: Cay19521-1
Lanosterol is a naturally-occurring sterol and biosynthetic precursor of several animal, fungal, and protozoan steroids, including cholesterol and ergosterol. Defects in the processing of lanosterol contribute to a wide variety of disorders, including the formation of cataracts. Similarly, certain fungicides act by...
| Schlagworte: | 3beta-hydroxy-8,24-Lanostadiene, 8,24-Lanostadien-3beta-ol, NSC 60677, lanosta-8,24-dien-3beta-ol |
| Anwendung: | Naturally-occurring sterol |
| CAS | 79-63-0 |
| MW: | 426.7 D |
ab 106,00 €
Ro 48-8071
Artikelnummer: Cay10006415-10
Oxidosqualene cyclase (OSC) is a microsomal enzyme that catalyzes the cyclization of monooxidosqualene to lanosterol in the cholesterol synthetic pathway. Ro 48-8071 is an inhibitor of oxidosqualene cyclase (OSC) that has low-density lipoprotein (LDL) cholesterol lowering activity similar to the...
| Schlagworte: | (4-bromophenyl)[2-fluoro-4-[[6-(methyl-2-propenylamino)hexyl]oxy]phenyl]-methanone |
| Anwendung: | OSC inhibitor |
| CAS | 161582-11-2 |
| MW: | 448.4 D |
ab 57,00 €
BIBB 515
Artikelnummer: Cay10010517-5
2,3-Oxidosqualene cyclase (OSC) is an important enzyme in the biosynthesis of animal, plant, and fungal sterols. OSC catalyzes the conversion of (3S)-2,3-oxidosqualene to lanosterol, a precursor to cholesterol, in mammals and fungi. BIBB 515 is a selective and potent inhibitor of OSC in vivo with an ED50 value of...
| Schlagworte: | 1-(4-chlorobenzoyl)-4-[[4-(4,5-dihydro-2-oxazolyl)phenyl]methylene]-piperidine |
| Anwendung: | OSC inhibitor |
| CAS | 156635-05-1 |
| MW: | 380.9 D |
ab 61,00 €
Anti-LSS
Artikelnummer: ARG57419.100
Protein function: Catalyzes the cyclization of (S)-2,3 oxidosqualene to lanosterol, a reaction that forms the sterol nucleus. Through the production of lanosterol may regulate lens protein aggregation and increase transparency. [The UniProt Consortium]
| Schlagworte: | Anti-OSC, Anti-LSS, Anti-hOSC, EC=5.4.99.7, Anti-Lanosterol synthase, Anti-Oxidosqualene--lanosterol cyclase,... |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | mouse |
658,00 €
Human LSS / Lanosterol synthase ELISA Kit
Artikelnummer: G-HUFI01671.96
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
641,00 €
Anti-LSS
Artikelnummer: ATA-HPA032060.100
Protein function: Key enzyme in the cholesterol biosynthesis pathway. Catalyzes the cyclization of (S)-2,3 oxidosqualene to lanosterol, a reaction that forms the sterol nucleus (PubMed:14766201, PubMed:7639730, PubMed:26200341). Through the production of lanosterol may regulate lens protein aggregation and increase...
| Schlagworte: | Anti-OSC, Anti-LSS, Anti-hOSC, Anti-Lanosterol synthase, Anti-Oxidosqualene--lanosterol cyclase,... |
| Anwendung: | IHC, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 239,00 €
Anti-LSS
Artikelnummer: ATA-HPA032062.100
Protein function: Key enzyme in the cholesterol biosynthesis pathway. Catalyzes the cyclization of (S)-2,3 oxidosqualene to lanosterol, a reaction that forms the sterol nucleus (PubMed:14766201, PubMed:7639730, PubMed:26200341). Through the production of lanosterol may regulate lens protein aggregation and increase...
| Schlagworte: | Anti-OSC, Anti-LSS, Anti-hOSC, Anti-Lanosterol synthase, Anti-Oxidosqualene--lanosterol cyclase,... |
| Anwendung: | IHC, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 239,00 €