Zu "K01634" wurden 21 Artikel gefunden!
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A6770
Artikelnummer: TGM-T36833-10mg
Description: A6770 is an inhibitor of sphingosine-1-phosphate (S1P) lyase.1It induces accumulation of [3H]sphinganine-1-phosphate ([3H]dhS1P), an S1P lyase substrate, in IT-79MTNC3 cells that endogenously express high levels of S1P lyase (EC50= <0.01 µM), an effect that is reduced in the presence of vitamin B6(EC50=...
| Anwendung: | S1P lyase inhibitor |
| CAS | 1331754-16-5 |
| MW: | 140.142 D |
ab 193,00 €
S1PL-IN-31
Artikelnummer: TGM-T83910-10mg
Description: S1PL-IN-31 is a dual-function chemical compound acting as an inhibitor of sphingosine-1-phosphate (S1P) lyase with an IC50 value of 210 nM and as an antagonist of the Smoothened (Smo) receptor with an IC50 of 440 nM. Demonstrating therapeutic potential, this compound, at a dosage of 2 mg/kg per day,...
| Schlagworte: | S1P Lyase Inhibitor 31, S1PL Inhibitor 31, Sphingosine-1-Phosphate Lyase Inhibitor 31 |
| Anwendung: | S1P lyase inhibitor |
| CAS | 1538574-95-6 |
| MW: | 454.95 D |
ab 169,00 €
2-ATHBI
Artikelnummer: TGM-T19778-1mg
Description: 2-ATHBI is a S1P lyase inhibitor. Target: Others. Smiles: CCC(O)(O)C(O)(O)c1cnc([nH]1)C(C)=O. References: Wang L, Ren B, Liu Y, Lu Y, Chang F, Yang L. 2-acetyl-4-tetrahydroxybutylimidazole and 4-methylimidazole in caramel colours, vinegar and beverages in China. Food Addit Contam Part B Surveill....
| Schlagworte: | THI |
| Anwendung: | S1P lyase inhibitor |
| CAS | 94944-70-4 |
| MW: | 230.22 D |
ab 48,00 €
Anti-SGPL1
Artikelnummer: CSB-PA088132.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: SGPL1. Antigen Species: Human
| Schlagworte: | Anti-S1PL, Anti-hSPL, Anti-SPL 1, Anti-SP-lyase 1, Anti-Sphingosine-1-phosphate lyase 1, Anti-Sphingosine-1-phosphate... |
| Anwendung: | ELISA, WB, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 163,00 €
Anti-SGPL1
Artikelnummer: CSB-PA266237.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: SGPL1. Antigen Species: Human
| Schlagworte: | Anti-S1PL, Anti-hSPL, Anti-SPL 1, Anti-SP-lyase 1, Anti-Sphingosine-1-phosphate lyase 1, Anti-Sphingosine-1-phosphate... |
| Anwendung: | ELISA, WB, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 163,00 €
Sphingosine-1-Phosphate Lyase Fluorogenic Substrate
Artikelnummer: Cay13238-1
S1P lyase fluorogenic substrate is a substrate of S1P lyase, leading to the production of the fluorescent product umbelliferone (7-hydroxycoumarin) under appropriate conditions. This compound is intended to be used to monitor or measure S1P lyase activity.Formal Name:...
| Schlagworte: | S1P Lyase Fluorogenic Substrate, 2S-ammonio-3R-hydroxy-5-((2-oxo-2H-chromen-7-yl)oxy)pentyl hydrogen phosphate |
| Anwendung: | S1P lyase activity measurement |
| CAS | 1166838-84-1 |
| MW: | 359.3 D |
ab 274,00 €
2-Acetyl-5-tetrahydroxybutyl Imidazole
Artikelnummer: Cay13222-1
2-Acetyl-5-tetrahydroxybutyl imidazole (THI) is an inhibitor of sphingosine-1-phosphate (S1P) lyase in vivo. THI is not active at S1P lyase in cell-free or cell-based assays but is converted to A6770 in vivo, which is subsequently activated by phosphorylation. In mice, THI (50 µg/ml in drinking water) increases S1P...
| Schlagworte: | 2-Acetyl-4-tetrahydroxybutyl Imidazole, 2-ATHBI, THI, 1-[5-[(1R,2S,3R)-1,2,3,4-tetrahydroxybutyl]-1H-imidazol-2-yl]-ethanone |
| Anwendung: | S1P lyase inhibitor |
| CAS | 94944-70-4 |
| MW: | 230.2 D |
ab 86,00 €
S1PL-IN-31
Artikelnummer: Cay39826-1
S1PL-IN-31 is an inhibitor of sphingosine-1-phosphate (S1P) lyase (IC50 = 210 nM). It is also an antagonist of the Smoothened (Smo) receptor (IC50 = 440 nM). In vivo, S1PL-IN-31 (2 mg/kg per day) prevents cervical and thoracic lymphocyte infiltration and neuromuscular weakness in a rat model of experimental...
| Schlagworte: | S1P Lyase Inhibitor 31, S1PL Inhibitor 31, Sphingosine-1-Phosphate Lyase Inhibitor 31,... |
| Anwendung: | S1P lyase inhibitor |
| CAS | 1538574-95-6 |
| MW: | 455 D |
ab 93,00 €
Mouse SGPL1 (Sphingosine 1 Phosphate Lyase 1) ELISA Kit
Artikelnummer: ELK-ELK6869.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Mouse SGPL1. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Mouse SGPL1. Next,...
| Schlagworte: | S1PL, mSPL, SPL 1, SP-lyase 1, Sphingosine-1-phosphate lyase 1, Sphingosine-1-phosphate aldolase |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | mouse |
ab 365,00 €
A6770
Artikelnummer: Cay29972-1
A6770 is an inhibitor of sphingosine-1-phosphate (S1P) lyase. It induces accumulation of [3H]sphinganine-1-phosphate ([3H]dhS1P), an S1P lyase substrate, in IT-79MTNC3 cells that endogenously express high levels of S1P lyase (EC50 = 6 (EC50 = 98%. Formulation: (Request formulation change), A crystalline solid....
| Schlagworte: | 1-[5-(hydroxymethyl)-1H-imidazol-2-yl]-ethanone |
| Anwendung: | S1P lyase inhibitor |
| CAS | 1331754-16-5 |
| MW: | 140.1 D |
ab 109,00 €
Mouse Sgpl1 / Sphingosine-1-phosphate lyase 1 ELISA Kit
Artikelnummer: G-MOFI00450.96
| Anwendung: | ELISA |
| Spezies-Reaktivität: | mouse |
694,00 €
4-Deoxypyridoxine Phosphate
Artikelnummer: Cay29973-1
4-Deoxypyridoxine phosphate is a vitamin B6 analog and an inhibitor of sphingosine-1-phosphate (S1P) lyase. It induces accumulation of [3H]sphinganine-1-phosphate ([3H]dhS1P), an S1P lyase substrate, in IT-79MTNC3 cells that endogenously express high levels of S1P lyase (EC50s = 100 µM in the absence and presence of...
| Schlagworte: | 4-Deoxypyridoxine Phosphate, DOP Phosphate, DOP-P, NSC 29870, 5-hydroxy-4,6-dimethyl-3-pyridinemethanol, 3-(dihydrogen... |
| Anwendung: | Vitamin B6 analog, Sphingosine-1-phosphate lyase 1 (S1PL) inhibitor |
| CAS | 883-84-1 |
| MW: | 233.2 D |
ab 43,00 €