Zu "K01542" wurden 31 Artikel gefunden!
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Potassium-transporting ATPase alpha chain 1 (ATP4A),...
Artikelnummer: CSB-EP002342HU.1
Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 350-783aa. Protein Length: Partial. Tag Info: N-terminal 10xHis-tagged and C-terminal Myc-tagged. Target Protein Sequence: TVTVCLSLTA KRLASKNCVV KNLEAVETLG STSVICSDKT GTLTQNRMTV SHLWFDNHIH TADTTEDQSG QTFDQSSETW RALCRVLTLC NRAAFKSGQD AVPVPKRIVI...
| Schlagworte: | ATP4A, EC=7.2.2.19, Proton pump, Gastric H(+)/K(+) ATPase subunit alpha, Potassium-transporting ATPase alpha chain 1,... |
| Anwendung: | Activity not tested |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 54.6 kD |
ab 283,00 €
Esomeprazole
Artikelnummer: Cay40851-100
Esomeprazole is an inhibitor of the gastric H+/K+-ATPase and the (S) enantiomer of omeprazole (Cay-14880). It reversibly inhibits the activity of the H+/K+-ATPase in an enzyme assay. Esomeprazole (30 mg/kg, s.c.) inhibits histamine-induced gastric acid secretion in rats. Formulations containing esomeprazole in...
| Schlagworte: | (-)-Omeprazole, (S)-Omeprazole, 6-methoxy-2-[(S)-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole |
| Anwendung: | H+/K+-ATPase inhibitor |
| CAS | 119141-88-7 |
| MW: | 345.4 D |
ab 131,00 €
Omeprazole sulfide-d3
Artikelnummer: Cay40260-1
Omeprazole sulfide-d3 is intended for use as an internal standard for the quantification of omeprazole sulfide (Cay-18885) by GC- or LC-MS. Omeprazole sulfide is an active metabolite of the gastric H+/K+ ATPase inhibitor omeprazole (Cay-14880). Omeprazole sulfide has been used as a precursor in the synthesis of the...
| Schlagworte: | OMEP sulfide-d3, OMP sulfide-d3, OMZ sulfide-d3, Pyrmetazole-d3, Ufiprazole-d3,... |
| Anwendung: | GC-MS, LC-MS internal standard, quantification, active omeprazole metabolite |
| MW: | 332.4 D |
ab 221,00 €
Anti-ATP4A
Artikelnummer: NSJ-RQ7146
0.5mg/ml if reconstituted with 0.2ml sterile DI water. The protein encoded by this gene belongs to a family of P-type cation-transporting ATPases. The gastric H+, K+-ATPase is a heterodimer consisting of a high molecular weight catalytic alpha subunit and a smaller but heavily glycosylated beta subunit. This enzyme...
| Schlagworte: | Anti-Proton pump, Anti-Gastric H(+)/K(+) ATPase subunit alpha, Anti-Potassium-transporting ATPase alpha chain 1, ATP4A... |
| Anwendung: | WB, IHC (paraffin), FC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
755,00 €
Mouse ATP4a (ATPase, H+/K+ Exchanging Alpha Polypeptide)...
Artikelnummer: ELK-ELK6337.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Mouse ATP4a. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Mouse ATP4a. Next,...
| Schlagworte: | Proton pump, Gastric H(+)/K(+) ATPase subunit alpha, Potassium-transporting ATPase alpha chain 1 |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | mouse |
ab 365,00 €
Omeprazole
Artikelnummer: Cay14880-100
Omeprazole is an inhibitor of gastric H+/K+ ATPase (IC50 = 1.1 µM for the pig ATPase). It is a racemic mixture of esomeprazole (Cay-17303) and (R)-omeprazole (Cay-18874). Omeprazole (100 µM) decreases zymosan-induced oxygen free radical production in isolated human neutrophils. It is active against 17 strains of H....
| Schlagworte: | OMEP, OMP, OMZ, 6-methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole |
| Anwendung: | Gastric H+/K+ ATPase pump inhibitor |
| CAS | 73590-58-6 |
| MW: | 345.4 D |
ab 43,00 €
Pantoprazole
Artikelnummer: Cay21345-1
Pantoprazole is a proton pump inhibitor that inhibits H+/K+-ATPase activity in porcine gastric membrane vesicles with an IC50 value of 6.8 µM. It reduces basal gastric acid secretion in pylorus-ligated rats (ED50 = 1.3 mg/kg) and inhibits mepirizole-induced increases in gastric acid secretion in an anesthetized rat...
| Schlagworte: | BY 1023, SKF 96022, 6-(difluoromethoxy)-2-[[(3,4-dimethoxy-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole |
| Anwendung: | Gastric H+/K+ ATPase pump inhibitor |
| CAS | 102625-70-7 |
| MW: | 383.4 D |
ab 43,00 €
(R)-Omeprazole (sodium salt)
Artikelnummer: Cay18874-1
(R)-Omeprazole is an inhibitor of the gastric H+/K+ ATPase and an enantiomer of esomeprazole (Cay-17303). It inhibits acid secretion induced by histamine (Cay-33828) in isolated rabbit gastric glands (IC50 = 781 µM) to a lesser extent than esomeprazole. (R)-Omeprazole (30 mg/kg) inhibits histamine-induced stomach...
| Schlagworte: | 6-methoxy-2-[(R)-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole, monosodium salt |
| Anwendung: | H+/K+ exchanging, alpha / beta polypeptide inhibitor |
| CAS | 161796-77-6 |
| MW: | 368.4 D |
ab 109,00 €
Omeprazole-d3
Artikelnummer: Cay22087-1
Omeprazole-d3 is intended for use as an internal standard for the quantification of omeprazole (Cay-14880) by GC- or LC-MS. Omeprazole is an inhibitor of gastric H+/K+ ATPase (IC50 = 1.1 µM for the pig ATPase). It is a racemic mixture of esomeprazole (Cay-17303) and (R)-omeprazole (Cay-18874). Omeprazole (100 µM)...
| Schlagworte: | OMEP-d3, OMP-d3, OMZ-d3, 6-methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole-4,5,7-d3 |
| Anwendung: | GC-MS, LC-MS, internal standard |
| CAS | 934293-92-2 |
| MW: | 348.4 D |
ab 156,00 €
Vonoprazan (fumarate)
Artikelnummer: Cay24200-500
Vonoprazan is a selective, reversible, and potassium-competitive proton pump inhibitor that inhibits gastric H+/K+ ATPase (IC50 = 17 nM) but does not inhibit porcine Na+/K+ ATPase activity when used at a concentration of 10 µM. It maintains its inhibitory effect in both weakly acidic (pH 6.5) and neutral (pH 7.5)...
| Schlagworte: | TAK-438, 5-(2-fluorophenyl)-N-methyl-1-(3-pyridinylsulfonyl)-1H-pyrrole-3-methanamine, 2-butenedioate |
| Anwendung: | Proton pump inhibitor |
| CAS | 1260141-27-2 |
| MW: | 461.5 D |
ab 60,00 €
Rabeprazole-d4 (sodium salt)
Artikelnummer: Cay26118-500
Rabeprazole-d4 is intended for use as an internal standard for the quantification of rabeprazole (Cay-14939) by GC- or LC-MS. Rabeprazole is a proton pump inhibitor that selectively and irreversibly inhibits the gastric H+/K+ ATPase (IC50 = 72 nM). It can be activated more rapidly and over a greater pH range than...
| Schlagworte: | 2-[[[4-(3-methoxypropoxy)-3-methyl-2-pyridinyl]methyl]sulfinyl]-1H-benzimidazole-4,5,6,7-d4, monosodium salt |
| Anwendung: | GC-MS, LC-MS, Internal standard, Proton pump inhibitor |
| MW: | 385.4 D |
ab 341,00 €
Rabeprazole
Artikelnummer: LKT-R0105.10
A proton pump/ATP-ase inhibitor.
| Schlagworte: | Rabeprazole Sodium, H+/K+ exchanging, alpha/beta polypeptide inhibitor |
| Anwendung: | Proton pump inhibitor |
| CAS | 117976-89-3 |
| MW: | 359,44 D |
ab 135,00 €