Zu "K01425" wurden 69 Artikel gefunden!
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Glutaminase 1 (glsA1), Escherichia coli, recombinant
Artikelnummer: CSB-EP302868ENV.1
Organism: Escherichia coli (strain K12). Source: E.coli. Expression Region: 1-310aa. Protein Length: Full Length. Tag Info: N-terminal 6xHis-GST-tagged. Target Protein Sequence: MLDANKLQQA VDQAYTQFHS LNGGQNADYI PFLANVPGQL AAVAIVTCDG NVYSAGDSDY RFALESISKV CTLALALEDV GPQAVQDKIG ADPTGLPFNS VIALELHGGK PLSPLVNAGA...
| Schlagworte: | ybaS, b0485, Glutaminase 1, Recombinant Escherichia coli Glutaminase 1 (glsA1) |
| Anwendung: | Activity not tested |
| Exprimiert in: | E.coli |
| Ursprungsart: | E.coli |
| MW: | 62.9 kD |
ab 354,00 €
Glutaminase liver isoform, mitochondrial (GLS2), human,...
Artikelnummer: CSB-EP887058HU.1
Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 15-602aa. Protein Length: Full Length of Mature Protein. Tag Info: N-terminal 6xHis-SUMO-tagged. Target Protein Sequence: GSHCGRGGWG HPSRSPLLGG GVRHHLSEAA AQGRETPHSH QPQHQDHDSS ESGMLSRLGD LLFYTIAEGQ ERIPIHKFTT ALKATGLQTS DPRLRDCMSE MHRVVQESSS...
| Schlagworte: | GA, GLS, GLS2, L-glutaminase, L-glutamine amidohydrolase, Glutaminase liver isoform, mitochondrial, Recombinant Human... |
| Anwendung: | Activity not tested |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 80.7 kD |
ab 283,00 €
Anti-GLS
Artikelnummer: CSB-PA177709.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: GLS. Antigen Species: Human
| Schlagworte: | Anti-GLS, Anti-GLS1, AAD20 antibody, DKFZp686O15119 antibody, FLJ10358 antibody, GAC antibody, GAM antibody, GLS antibody,... |
| Anwendung: | ELISA, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 163,00 €
Anti-GLS
Artikelnummer: CSB-PA969762.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: GLS. Antigen Species: Human
| Schlagworte: | Anti-GLS, Anti-GLS1, AAD20 antibody, DKFZp686O15119 antibody, FLJ10358 antibody, GAC antibody, GAM antibody, GLS antibody,... |
| Anwendung: | ELISA, WB, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 163,00 €
IPN60090
Artikelnummer: Cay35855-1
IPN60090 is an inhibitor of glutaminase 1 (GLS1, IC50 = 0.031 µM for the glutaminase C isoform). It is selective for GLS1 over GLS2 (IC50 = >50 µM), as well as panels of 80 ion channels and receptors and 97 kinases at 10 µM. IPN60090 also binds to zinc finger SWIM domain-containing protein 4 (ZSWIM4, Kd = 2.98 µM)....
| Schlagworte: | IACS-6274,... |
| Anwendung: | GLS1 inhibitor |
| CAS | 1853164-83-6 |
| MW: | 532.5 D |
ab 240,00 €
CB-839
Artikelnummer: Cay22038-5
CB-839 is an orally bioavailable noncompetitive inhibitor of the glutaminase 1 (GLS1) splice variants, kidney-type (KGA) and glutaminase C (GAC), which convert glutamine into glutamate. CB-839 inhibits human recombinant GAC with IC50 values of less than 50 nM, varying based on the length of preincubation. It...
| Schlagworte: | GLS1 Inhibitor III,... |
| Anwendung: | Glutaminase inhibitor |
| CAS | 1439399-58-2 |
| MW: | 571.6 D |
ab 77,00 €
Glutaminase C Inhibitor 11
Artikelnummer: Cay39883-1
Glutaminase C inhibitor 11 is an inhibitor of glutaminase C (GAC). It inhibits GAC enzyme activity (EC50 = 10.64 nM) and reduces the viability of A549 non-small cell lung cancer (NSCLC) cells (IC50 = 4.025 nM). Glutaminase C inhibitor 11 (0.1 and 1 µM) reduces colony formation by, and intracellular glutamate levels...
| Schlagworte: | (R)-2-(3-phenoxyphenyl)-N-(5-((1-(pyridazin-3-yl)pyrrolidin-3-yl)amino)-1,3,4-thiadiazol-2-yl)acetamide |
| Anwendung: | GAC (GLS, Glutaminase kidney isoform, mitochondrial) inhibitor |
| MW: | 473.6 D |
ab 106,00 €
Glutaminase (EC 3.5.1.2), Escherichia coli
Artikelnummer: NZY-AE00071
Glutaminase (EC 3.5.1.2) is purified from a recombinant E. coli strain. Glutaminase is an amidohydrolase enzyme which generates glutamate from glutamine. Glutaminase has tissue-specific isoenzymes. Importantly, glutaminase is found in glial cells. Glutaminase is expressed in periportal hepatocytes, where it...
| Schlagworte: | ybaS, b0485, Glutaminase 1 |
| Anwendung: | Enzyme assays |
169,00 €
BPTES
Artikelnummer: Cay19284-5
BPTES is an allosteric inhibitor of kidney-type glutaminase 1 (GLS1, IC50 = 3.3 µM) that drives the formation of inactive GLS1 tetramers. It is selective for GLS1 over GLS2, glutamate dehydrogenase, and gamma-glutamyl transpeptidase. BPTES decreases glutaminase activity and reduces proliferation of aerobic P493...
| Schlagworte: | N,N'-[thiobis(2,1-ethanediyl-1,3,4-thiadiazole-5,2-diyl)]bis-benzeneacetamide |
| Anwendung: | GLS inhibitor |
| CAS | 314045-39-1 |
| MW: | 524.7 D |
ab 43,00 €
Mouse GLS2 (Glutaminase 2) ELISA Kit
Artikelnummer: ELK-ELK6204.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Mouse GLS2. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Mouse GLS2. Next,...
| Schlagworte: | GLS, LGA, Gls2, Kiaa4146, L-glutaminase, L-glutamine amidohydrolase, Glutaminase liver isoform, mitochondrial |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | mouse |
ab 365,00 €
Glutaminase Inhibitor Compound 968
Artikelnummer: Cay17199-5
Glutaminase inhibitor compound 968 is a cell-permeable, reversible inhibitor of a mitochondrial glutaminase splice variant, glutaminase C (IC50 = ~2.5 µM), which is commonly found in cancer cells. Through this action, glutaminase inhibitor compound 968 blocks transformation induced by Rho GTPases and inhibits the...
| Schlagworte: | 5-[3-bromo-4-(dimethylamino)phenyl]-2,3,5,6-tetrahydro-2,2-dimethyl-benzo[a]phenanthridin-4(1H)-one |
| Anwendung: | Glutaminase inhibitor |
| CAS | 311795-38-7 |
| MW: | 475.4 D |
ab 43,00 €
Glutaminase Assay Kit (Colorimetric)
Artikelnummer: ARG82767.96
This Glutaminase Assay Kit (Colorimetric) is a detection kit for the quantification of Glutaminase activity in cells, bacteria and tissue samples. Protein function: Catalyzes the first reaction in the primary pathway for the renal catabolism of glutamine. Plays a role in maintaining acid-base homeostasis. Regulates...
| Schlagworte: | GLS, GLS1 |
| Anwendung: | FA |
| Spezies-Reaktivität: | broad |
824,00 €