Zu "K01398" wurden 179 Artikel gefunden!
Für die Filterung wurden keine Ergebnisse gefunden!
CTS-1027
Artikelnummer: TGM-T15015-2mg
Description: CTS-1027 is a small molecule inhibitor of MMPs (IC50s: 0.3 nM, 0.5 nM for MMP2, MMP13). It has > 1,000 fold selectivity over MMP1. Target: Others. Smiles: ONC(=O)C1(CS(=O)(=O)c2ccc(Oc3ccc(Cl)cc3)cc2)CCOCC1. References: Kahraman A, et al. Matrix metalloproteinase inhibitor, CTS-1027, attenuates liver...
| Schlagworte: | Ro 1130830, RS 130830 |
| Anwendung: | MMP2/9/13 inhibitor |
| CAS | 193022-04-7 |
| MW: | 425.88 D |
95,00 €
ARP-100
Artikelnummer: TGM-T14322-100mg
Description: ARP-100 (MMP-2 Inhibitor III) is a potent and selective matrix metalloproteinase MMP-2 inhibitor (IC50=12 nM). ARP-100 interacts with the S1' pocket of MMP-2 and exhibits anti-invasive properties in an in vitro invasion Matrigel model. ARP-100 has low inhibitory activity against MMP-1 (>50 µM), MMP-3...
| Schlagworte: | MMP-2 Inhibitor III |
| Anwendung: | MMP-2 inhibitor |
| CAS | 704888-90-4 |
| MW: | 364.42 D |
ab 32,00 €
SD-2590 HCl
Artikelnummer: TGM-T24775-1mg
Description: SD-2590 HCl is an MMP-2,-3, -9, -8, 13, and -14 inhibitor. Target: Others. Smiles: Cl.O=C(NO)C1(CCN(CCOC)CC1)S(=O)(=O)C2=CC=C(OC3=CC=C(OC(F)(F)F)C=C3)C=C2. References: Becker DP, Barta TE, Bedell LJ, Boehm TL, Bond BR, Carroll J, Carron CP, Decrescenzo GA, Easton AM, Freskos JN, Funckes-Shippy CL, Heron...
| Schlagworte: | SD2590 Hydrochloride, SD 2590 Hydrochloride, SD2590 HCl, SD-2590 Hydrochloride |
| Anwendung: | MMP2 / MMP13 / MMP9 / MMP8 / MMP3 inhibitor |
| CAS | 226395-93-3 |
| MW: | 554.96 D |
ab 108,00 €
ONO 4817
Artikelnummer: TGM-T21814-1mg
Description: ONO-4817 is a broad-spectrum matrix metalloproteinase (MMP) inhibitor that potentially mitigates atherosclerotic neointimal proliferation and atheromatous plaque progression by suppressing matrix metalloproteinases (MMPs). It effectively reduces the development of aortic intimal hyperplasia in...
| Anwendung: | MMP-2 / MMP-9 inhibitor |
| CAS | 223472-31-9 |
| MW: | 416.47 D |
ab 259,00 €
SB-3CT
Artikelnummer: TGM-T2009-1mg
Description: SB-3CT is a potent and specific gelatinase inhibitor for MMP-2 (Ki = 13.9 nM) and MMP-9 (Ki = 600 nM). Target: MMP. Smiles: O=S(=O)(CC1CS1)c1ccc(Oc2ccccc2)cc1. References: Brown S, et al. J Am Chem Soc. 2000, 122 (28), 6799-6800.
| Anwendung: | MMP-2 / MMP-9 inhibitor |
| CAS | 292605-14-2 |
| MW: | 306.4 D |
ab 41,00 €
Ilomastat
Artikelnummer: TGM-T2743-100mg
Description: Ilomastat (GM6001) (GM6001, Galardin) is a broad spectrum matrix metalloprotease (MMP) inhibitor. Target: MMP. Smiles: CNC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CC(C)C)CC(=O)NO. References: Grobelny D, et al. Biochemistry, 1992, 31(31), 7152-714.
| Schlagworte: | GM6001, Galardin |
| Anwendung: | Targets matrix metalloproteinase-2 (gelatinase A) [EC:3.4.24.24] (MMP2) |
| CAS | 142880-36-2 |
| MW: | 388.46 D |
ab 41,00 €
BPHA
Artikelnummer: TGM-T36712-100mg
Description: BPHA (MMP-2/MMP-9 Inhibitor II) is a potent, selective and orally active inhibitor of MMP-2, MMP-9 and MMP-14 with IC50s of 12 nM, 16 nM and 17 nM, respectively.BPHA does not inhibit MMP-1, -3 and -7 (IC50s of 974, >1000 and 795 nM, respectively).BPHA has anti-angiogenic and BPHA has anti-angiogenic and...
| Schlagworte: | MMP-2/MMP-9 Inhibitor II |
| Anwendung: | MMP2 / MMP9 inhibitor |
| CAS | 193807-60-2 |
| MW: | 396.46 D |
ab 210,00 €
Pyridoxatin
Artikelnummer: TGM-T70891-1mg
Description: Pyridoxatin is a fungal metabolite that inhibits production of thiobarbituric acid reactive substance (TBARS). Pyridoxatin inhibits hemolysis induced by the free radical generator AAPH and is active against C. albicans. Target: Others. Smiles: CC1CC(C)C(C(C1)C=C)c1c(O)ccn(O)c1=O
| Anwendung: | Antibiotic |
| CAS | 135529-30-5 |
| MW: | 263.33 D |
ab 193,00 €
MMP-2 Protein, Human, Recombinant (His)
Artikelnummer: TGM-TMPJ-00362-10ug
Description: 72 kDa type IV collagenase also known as matrix metalloproteinase-2 (MMP-2) and gelatinase A is an enzyme that in humans is encoded by the MMP2 gene.It belongs to the matrix metalloproteinase (MMP) family. Matrix metalloproteinases (MMPs) are a family of zinc-dependent endopeptidases that degrade...
| Schlagworte: | 72 kDa Type IV Collagenase, MMP-2, CLG4A, MMP2, 72 kDa Gelatinase, TBE-1, Gelatinase A, Matrix Metalloproteinase-2 |
| MW: | 72 kD |
ab 180,00 €
MMP-2 Protein, Mouse, Recombinant (His)
Artikelnummer: TGM-TMPY-02290-100ug
Description: MMP-2 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 30.9 kDa and the accession number is P33434-1.
| Schlagworte: | matrix metallopeptidase 2, MMP-2, GelA, Clg4a |
| MW: | 30.9 kD |
ab 389,00 €
Prinomastat hydrochloride
Artikelnummer: TGM-T12539-100mg
Description: Prinomastat hydrochloride is a orally active inhibitor of metalloproteinase (MMP)(MMP-1, MMP-3 and MMP-9 with IC50s of 79, 6.3 and 5.0 nM , respectively),with Antitumor avtivity. Target: MMP. Smiles: S(=O)(=O)(N1[C@@H](C(NO)=O)C(C)(C)SCC1)C2=CC=C(OC=3C=CN=CC3)C=C2.Cl. References: Sørensen MD, et al....
| Schlagworte: | KB-R9896 hydrochloride, AG3340 hydrochloride |
| Anwendung: | MMP-2 inhibitor |
| CAS | 1435779-45-5 |
| MW: | 459.97 D |
ab 1.049,00 €
72KDA type IV collagenase (Mmp2), rat, recombinant
Artikelnummer: CSB-EP014666RA.1
Organism: Rattus norvegicus (Rat). Source: E.coli. Expression Region: 110-662aa. Protein Length: Full Length of Mature Protein. Tag Info: N-terminal 6xHis-SUMO-tagged. Target Protein Sequence: YNFFPRKPKW DKNQITYRII GYTPDLDPET VDDAFARALK VWSDVTPLRF SRIHDGEADI MINFGRWEHG DGYPFDGKDG LLAHAFAPGT GVGGDSHFDD DELWTLGEGQ...
| Schlagworte: | Mmp2, Recombinant Rat 72KDA type IV collagenase (Mmp2) |
| Anwendung: | Activity not tested |
| Exprimiert in: | E.coli |
| Ursprungsart: | rat |
| MW: | 78.1 kD |
ab 283,00 €