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Anti-MME
Anti-MME

Artikelnummer: ABS-KC-570.100

Protein function: Thermolysin-like specificity, but is almost confined on acting on polypeptides of up to 30 amino acids (PubMed:15283675, PubMed:8168535). Biologically important in the destruction of opioid peptides such as Met- and Leu-enkephalins by cleavage of a Gly-Phe bond (PubMed:17101991). Able to cleave...
Schlagworte: Anti-Neprilysin, Anti-Atriopeptidase, Anti-Common acute lymphocytic leukemia antigen, Anti-CALLA, Anti-Enkephalinase,...
Anwendung: IHC
Wirt: Mouse
Spezies-Reaktivität: human
ab 206,00 €
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Anti-MME
Anti-MME

Artikelnummer: ABS-KC-571.100

Protein function: Thermolysin-like specificity, but is almost confined on acting on polypeptides of up to 30 amino acids (PubMed:15283675, PubMed:8168535). Biologically important in the destruction of opioid peptides such as Met- and Leu-enkephalins by cleavage of a Gly-Phe bond (PubMed:17101991). Able to cleave...
Schlagworte: Anti-Neprilysin, Anti-Atriopeptidase, Anti-Common acute lymphocytic leukemia antigen, Anti-CALLA, Anti-Enkephalinase,...
Anwendung: IHC
Wirt: Mouse
Spezies-Reaktivität: human
ab 206,00 €
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Anti-MME
Anti-MME

Artikelnummer: ABS-KC-572.100

Protein function: Thermolysin-like specificity, but is almost confined on acting on polypeptides of up to 30 amino acids (PubMed:15283675, PubMed:8168535). Biologically important in the destruction of opioid peptides such as Met- and Leu-enkephalins by cleavage of a Gly-Phe bond (PubMed:17101991). Able to cleave...
Schlagworte: Anti-Neprilysin, Anti-Atriopeptidase, Anti-Common acute lymphocytic leukemia antigen, Anti-CALLA, Anti-Enkephalinase,...
Anwendung: IHC
Wirt: Mouse
Spezies-Reaktivität: human
ab 206,00 €
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Anti-MME
Anti-MME

Artikelnummer: ABS-KC-4323.100

Protein function: Thermolysin-like specificity, but is almost confined on acting on polypeptides of up to 30 amino acids (PubMed:15283675, PubMed:8168535). Biologically important in the destruction of opioid peptides such as Met- and Leu-enkephalins by cleavage of a Gly-Phe bond (PubMed:17101991). Able to cleave...
Schlagworte: Anti-Neprilysin, Anti-Atriopeptidase, Anti-Common acute lymphocytic leukemia antigen, Anti-CALLA, Anti-Enkephalinase,...
Wirt: Mouse
Spezies-Reaktivität: human, rat, mouse
ab 232,00 €
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Sacubitril hemicalcium salt
Sacubitril hemicalcium salt

Artikelnummer: TGM-T4200-10mg

Description: Sacubitril hemicalcium salt (AHU377 calcium salt) is a potent NEP inhibitor with an IC50 of 5 nM. Sacubitril hemicalcium salt is a component of the heart failure medicine LCZ696. Sacubitril hemicalcium salt is a prodrug of LBQ657, which is an inhibitor of the zinc metallopeptidase neprilysin. Neprilysin...
Schlagworte: AHU377 calcium salt, AHU-377 (hemicalcium salt)
Anwendung: Neprilysin inhibitor
CAS 1369773-39-6
MW: 861.06 D
ab 34,00 €
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Ecadotril
Ecadotril

Artikelnummer: TGM-T31598-100mg

Description: Ecadotril is a neutral endopeptidase (NEP) inhibitor, which plays an anti hypertensive role. Target: Others. Smiles: [C@H](CC1=CC=CC=C1)(C(NCC(OCC2=CC=CC=C2)=O)=O)CSC(C)=O. References: Sáez J, Cifuentes L. Is racecadotril effective for acute diarrhea in children? -First update. Version 2. Medwave. 2016...
Schlagworte: S049, BP 1.02, BAY-y 7432, BAY y 7432, S.049
Anwendung: Targets neprilysin [EC:3.4.24.11] (MME, CD10)
CAS 112573-73-6
MW: 385.48 D
ab 1.520,00 €
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Candoxatrilat
Candoxatrilat

Artikelnummer: TGM-T30701-100mg

Description: Candoxatrilat (U 73967, UK69578) is an active neutral endopeptidase inhibitor that reduces atrial natriuretic peptide degradation. Target: Others. Smiles: C([C@@H](COCCOC)C(O)=O)C1(C(N[C@H]2CC[C@@H](C(O)=O)CC2)=O)CCCC1. References: Kaye B, Brearley CJ, Cussans NJ, Herron M, Humphrey MJ, Mollatt AR....
Schlagworte: UK69578, UK 69578, UK-69578, U 73967, U73967, U-73967
Anwendung: Targets neprilysin [EC:3.4.24.11] (MME, CD10)
CAS 123122-54-3
MW: 399.48 D
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Sacubitril
Sacubitril

Artikelnummer: TGM-T4574-100mg

Description: Sacubitril (AHU-377) is a potent NEP inhibitor with an IC50 of 5 nM and is a component of the heart failure medicine LCZ696. Target: Neprilysin. Smiles: CCOC(=O)[C@H](C)C[C@@H](Cc1ccc(cc1)-c1ccccc1)NC(=O)CCC(O)=O. References: Ksander GM,etal.Dicarboxylic acid dipeptide neutral endopeptidase inhibitors.J...
Schlagworte: AHU-377, AHU377, AHU 377
Anwendung: Targets neprilysin [EC:3.4.24.11] (MME, CD10)
CAS 149709-62-6
MW: 411.49 D
ab 57,00 €
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Racecadotril-d5
Racecadotril-d5

Artikelnummer: TGM-T71145-10mg

Description: Racecadotril-d5 is intended for use as an internal standard for the quantification of racecadotril by GC- or LC-MS. Racecadotril is a prodrug form of the neprilysin (NEP) inhibitor thiorphan. In vivo, racecadotril reduces or prevents castor oil-induced diarrhea without delaying intestinal transit in...
Anwendung: GC-MS, LC-MS internal standard, quantification, enkephalinase inhibitor
CAS 1246815-11-1
MW: 390.51 D
ab 122,00 €
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Thiorphan
Thiorphan

Artikelnummer: TGM-T7693-100mg

Description: Thiorphan is an neprilysin inhibitor (NEP, IC50 : 0.007 µM). Target: Neprilysin. Smiles: OC(=O)CNC(=O)C(CS)Cc1ccccc1. References: Chicau-Chovet M , Dubrasquet M , Chariot J , et al. Thiorphan and acetorphan inhibit gastric secretion by a central, non-opioid mechanism in the rat[J]. European Journal of...
Anwendung: Potent neprilysin inhibitor
CAS 76721-89-6
MW: 253.32 D
ab 31,00 €
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CD10 Protein, Mouse, Recombinant (His)
CD10 Protein, Mouse, Recombinant (His)

Artikelnummer: TGM-TMPY-01093-50ug

Description: CD10 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 82.2 kDa and the accession number is Q61391.
Schlagworte: membrane metallo-endopeptidase, C85356, 6030454K05Rik, NEP, CALLA, CD10, SFE
MW: 82.2 kD
599,00 €
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AHU-377-d4
AHU-377-d4

Artikelnummer: TGM-TMIH-0076-1mg

Description: AHU-377-d4 is a deuterated compound of AHU-377. Smiles: [2H]C([2H])(C(O)=O)C([2H])([2H])C(=O)N[C@@H](C[C@@H](C)C(=O)OCC)CC1=CC=C(C=C1)C1=CC=CC=C1
Anwendung: Neprilysin inhibitor, GC-MS, LC-MS, internal standard
CAS 1884269-07-1
MW: 415.52 D
ab 347,00 €
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