Zu "K01370" wurden 148 Artikel gefunden!
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Anti-Caspase-1 (p20) (mouse), clone Casper-1
Artikelnummer: AG-20B-0042-C100
Recognizes endogenous full-length and activated (p20 fragment) mouse caspase-1. Caspase-1 is the best-described inflammatory caspase. It processes the cytokines interleukin-1beta (IL-1beta) and IL-18 and induces pyroptotic cell death. Caspase-1 is activated by multiprotein complexes called Inflammasomes in response...
| Schlagworte: | Anti-CASP1, Anti-CASP-1, Anti-ICE, EC=3.4.22.36 |
| Anwendung: | WB, IHC, IP |
| Wirt: | Mouse |
| Spezies-Reaktivität: | mouse |
462,00 €
Anti-Caspase-1 (p20) (human), clone Bally-1
Artikelnummer: AG-20B-0048-C100
Recognizes endogenous full-length and activated (p20 fragment) human caspase-1. Caspase-1 is activated by multiprotein complexes called Inflammasomes in response to numerous stimuli that are detected through distinct inflammasomes. NLRC4 responds to cytosolic Caspase-1 is the best-described inflammatory caspase. It...
| Schlagworte: | Anti-CASP1, Anti-CASP-1, Anti-ICE |
| Anwendung: | WB |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
462,00 €
FLICA(TM) 660 Caspase-1 Assay Kit (25-50 tests)
Artikelnummer: ICT-9122
Kit includes 660-YVAD-FMK red caspase-1 probe, 10x Apoptosis Wash Buffer, Fixative, Technical Protocol. The red FLICA® 660-YVAD-FMK caspase-1 detection probe is comprised of the preferred affinity peptide sequence for active caspase-1 (YVAD), a far-red fluorescent 660 dye label, and a fluoromethyl ketone (FMK)...
| Anwendung: | FM, FC |
380,00 €
FAM-FLICA(R) Caspase 1 Assay Kit
Artikelnummer: ICT-97
This kits makes use of a cell-permeant green fluorecent probe (FAM-YVAD-FMK) that binds to active caspase-1 in living cells undergoing apoptosis. Excitation wavelength 488-492nm, emission 515-535nm.
| Anwendung: | FM, FC |
346,00 €
FAM-FLICA(R) Caspase 1 Assay Kit
Artikelnummer: ICT-98
This kits makes use of a cell-permeant green fluorecent probe (FAM-YVAD-FMK) that binds to active caspase-1 in living cells undergoing apoptosis. Excitation wavelength 488-492nm, emission 515-535nm.
| Anwendung: | FM, FC |
961,00 €
Emricasan
Artikelnummer: Cay22204-5
Emricasan is a pan-caspase inhibitor. Ex vivo, emricasan (10 mg/kg) prevents cold ischemia-warm reperfusion-induced sinusoidal endothelial cell (SEC) apoptosis and inhibits caspase-3 activation in rat liver by 55 and 94%, respectively. In vivo, emricasan reduces alanine aminotransferase (ALT) levels (ED50s = 95%....
| Schlagworte: | IDN-6556, PF-03491390,... |
| Anwendung: | Antiinflammatory, Caspase-1 inhibitor |
| CAS | 254750-02-2 |
| MW: | 569.5 D |
ab 39,00 €
Belnacasan
Artikelnummer: TGM-T6090-5mg
Description: Belnacasan (VX-765) is an orally active inhibitor of IL-converting enzyme/caspase-1. Target: Caspase. Smiles: CCO[C@@H]1OC(=O)C[C@@H]1NC(=O)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)c1ccc(N)c(Cl)c1)C(C)(C)C. References: Wannamaker W, et al....
| Schlagworte: | VX-765 |
| Anwendung: | Targets caspase 1 [EC:3.4.22.36] (CASP1) |
| CAS | 273404-37-8 |
| MW: | 508.99 D |
ab 31,00 €
Ac-YVAD-AFC
Artikelnummer: TGM-T78431-10mg
Description: Ac-YVAD-AFC is a fluorometric peptide substrate of caspase-1, featuring an excitation wavelength (lambda excitation) of 400 nm and an emission wavelength (lambda emission) of 505 nm [1] [2]. Smiles:...
| Anwendung: | Fluorogenic caspase-1 / caspase-4 substrate |
| CAS | 219137-85-6 |
| MW: | 719.66 D |
ab 94,00 €
Caspase-1 Protein, Human, Recombinant (HA)
Artikelnummer: TGM-TMPH-01055-100ug
Description: Caspase-1 Protein, Human, Recombinant (HA) is expressed in E. coli expression system with C-HA tag. The predicted molecular weight is 11.4 kDa and the accession number is P29466.
| Schlagworte: | ICE, IL1BCE, Interleukin-1 beta-converting enzyme, Interleukin-1 beta convertase, Caspase-1, p45, IL-1BC, IL1BC, CASP1,... |
| MW: | 11.4 kD |
ab 198,00 €
Ac-YVAD-CHO
Artikelnummer: TGM-T19883-1mg
Description: L 709049 is a biologically active compound that is a selective inhibitor of interleukin-1beta converting enzyme (Caspase-1). Caspase inhibitors interfere with the initiation of apoptosis and have multiple clinical applications. Smiles:...
| Schlagworte: | L-709049, L 709049, L709049 |
| Anwendung: | Caspase-1 inhibitor |
| CAS | 143313-51-3 |
| MW: | 492.52 D |
72,00 €
Emricasan
Artikelnummer: TGM-T6826-5mg
Description: Emricasan (IDN-6556) is a pan-caspase inhibitor with irreversible properties. Emricasan has anti-inflammatory and anti-apoptotic activity and can be used in the treatment of infections and liver failure, etc. Emricasan also inhibits Zika virus infections. Target: Caspase, Influenza Virus. Smiles:...
| Schlagworte: | IDN-6556, PF 03491390 |
| Anwendung: | Targets caspase 1 [EC:3.4.22.36] (CASP1) |
| CAS | 254750-02-2 |
| MW: | 569.5 D |
ab 38,00 €
Anti-Caspase-1 (Capture/Detector)
Artikelnummer: E-AN000010P.1
Caspase-1, also known as interleukin-1-beta (IL-1beta) -converting enzyme (ICE), is a member of the cysteine-aspartic protease (caspase) family . The caspase family are aspartic proteolytic enzymes that play a key role in apoptotic cell death and inflammation. Protein function: Thiol protease involved in a variety...
| Schlagworte: | Anti-Casp1, Anti-Il1bc, Caspase-1 Polyclonal Antibody(Capture/Detector) |
| Anwendung: | ELISA Capture/Detector |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | mouse |
ab 158,00 €