Zu "K01370" wurden 151 Artikel gefunden!
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Anti-Caspase-1 (p20) (mouse), clone Casper-1
Artikelnummer: AG-20B-0042-C100
Recognizes endogenous full-length and activated (p20 fragment) mouse caspase-1. Caspase-1 is the best-described inflammatory caspase. It processes the cytokines interleukin-1beta (IL-1beta) and IL-18 and induces pyroptotic cell death. Caspase-1 is activated by multiprotein complexes called Inflammasomes in response...
| Schlagworte: | Anti-CASP1, Anti-CASP-1, Anti-ICE, EC=3.4.22.36 |
| Anwendung: | WB, IHC, IP |
| Wirt: | Mouse |
| Spezies-Reaktivität: | mouse |
440,00 €
Anti-Caspase-1 (p20) (human), clone Bally-1
Artikelnummer: AG-20B-0048-C100
Recognizes endogenous full-length and activated (p20 fragment) human caspase-1. Caspase-1 is activated by multiprotein complexes called Inflammasomes in response to numerous stimuli that are detected through distinct inflammasomes. NLRC4 responds to cytosolic Caspase-1 is the best-described inflammatory caspase. It...
| Schlagworte: | Anti-CASP1, Anti-CASP-1, Anti-ICE |
| Anwendung: | WB |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
440,00 €
FLICA(TM) 660 Caspase-1 Assay Kit (25-50 tests)
Artikelnummer: ICT-9122
Kit includes 660-YVAD-FMK red caspase-1 probe, 10x Apoptosis Wash Buffer, Fixative, Technical Protocol. The red FLICA® 660-YVAD-FMK caspase-1 detection probe is comprised of the preferred affinity peptide sequence for active caspase-1 (YVAD), a far-red fluorescent 660 dye label, and a fluoromethyl ketone (FMK)...
| Anwendung: | FM, FC |
368,00 €
FAM-FLICA(R) Caspase 1 Assay Kit
Artikelnummer: ICT-97
This kits makes use of a cell-permeant green fluorecent probe (FAM-YVAD-FMK) that binds to active caspase-1 in living cells undergoing apoptosis. Excitation wavelength 488-492nm, emission 515-535nm.
| Anwendung: | FM, FC |
336,00 €
FAM-FLICA(R) Caspase 1 Assay Kit
Artikelnummer: ICT-98
This kits makes use of a cell-permeant green fluorecent probe (FAM-YVAD-FMK) that binds to active caspase-1 in living cells undergoing apoptosis. Excitation wavelength 488-492nm, emission 515-535nm.
| Anwendung: | FM, FC |
933,00 €
Pralnacasan
Artikelnummer: TGM-T16570-2mg
Description: Pralnacasan inhibits proinflammatory cytokines IL-18, IL-1beta , and IFN-gamma. Pralnacasan is an effective, non-peptide, and orally active interleukin-1beta converting enzyme inhibitor (Ki: 1.4 nM). Pralnacasan has the potential for osteoarthritis and rheumatoid arthritis treatment. Target: Others....
| Schlagworte: | VX-740, HMR 3480 |
| Anwendung: | Targets caspase 1 [EC:3.4.22.36] (CASP1) |
| CAS | 192755-52-5 |
| MW: | 523.54 D |
707,00 €
Imperatorin
Artikelnummer: TGM-T2845-100mg
Description: Imperatorin (8-Isopentenyloxypsoralene) is a modulator of p38, ERK pathway. Imperatorin increases BMP-2 expression (mRNA) and increases bone density/volume and mineralization in vivo. Target: TRP/TRPV Channel, NOD, AChR, AChE. Smiles: CC(C)=CCOc1c2occc2cc2ccc(=O)oc12. References: Koziol, E., &...
| Schlagworte: | 8-Isoamylenoxypsoralen, Ammidin, 8-Isopentenyloxypsoralene, Marmelosin, Pentosalen |
| Anwendung: | Apoptosis inducer, caspase-1 activity inhibitor |
| CAS | 482-44-0 |
| MW: | 270.28 D |
ab 41,00 €
Ac-YVAD-CMK
Artikelnummer: TGM-T36347-10mg
Description: Ac-YVAD-CMK (Ac-Tyr-Val-Ala-Asp-CMK) is a selective and irreversible inhibitor of Caspase-1 and inhibits pyroptosis, IL-1beta and IL-18. Ac-YVAD-CMK shows neuroprotective and anti-inflammatory capacity. Target: Immunology/Inflammation related, Pyroptosis, Caspase, IL Receptor. Smiles:...
| Schlagworte: | Ac-Tyr-Val-Ala-Asp-CMK, Ac-Tyr-Val-Ala-Asp-chloromethylketone, Caspase-1 Inhibitor II |
| Anwendung: | Caspase-1 inhibitor |
| CAS | 178603-78-6 |
| MW: | 540.99 D |
ab 63,00 €
Dabcyl-YVADAPV-EDANS
Artikelnummer: TGM-T35615-1mg
Description: Dabcyl YVADAPV EDANS is a fluorescent IL-1beta converting enzyme (ICE) substrate that can be used to detect ICE-like protease activity. Dabcyl YVADAPV EDANS detects fluorescence at lambdaex=360 nm, lambdaem=480 nm. Smiles:...
| Anwendung: | TR-FRET, fluorogenic caspase-1 substrate |
| CAS | 161877-70-9 |
| MW: | 1233.39 D |
301,00 €
Ac-YVAD-AFC
Artikelnummer: TGM-T78431-10mg
Description: Ac-YVAD-AFC is a fluorometric peptide substrate of caspase-1, featuring an excitation wavelength (lambda excitation) of 400 nm and an emission wavelength (lambda emission) of 505 nm [1] [2]. Smiles:...
| Anwendung: | Fluorogenic caspase-1 / caspase-4 substrate |
| CAS | 219137-85-6 |
| MW: | 719.66 D |
ab 93,00 €
Caspase-1 Protein, Human, Recombinant (HA)
Artikelnummer: TGM-TMPH-01055-100ug
Description: Caspase-1 Protein, Human, Recombinant (HA) is expressed in E. coli expression system with C-HA tag. The predicted molecular weight is 11.4 kDa and the accession number is P29466.
| Schlagworte: | ICE, IL1BCE, Interleukin-1 beta-converting enzyme, Interleukin-1 beta convertase, Caspase-1, p45, IL-1BC, IL1BC, CASP1,... |
| MW: | 11.4 kD |
ab 193,00 €
Ac-YVAD-CHO
Artikelnummer: TGM-T19883-100mg
Description: L 709049 is a biologically active compound that is a selective inhibitor of interleukin-1beta converting enzyme (Caspase-1). Caspase inhibitors interfere with the initiation of apoptosis and have multiple clinical applications. Smiles:...
| Schlagworte: | L-709049, L 709049, L709049 |
| Anwendung: | Caspase-1 inhibitor |
| CAS | 143313-51-3 |
| MW: | 492.52 D |
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