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Neutrophil elastase (ELANE), recombinant human
Neutrophil elastase (ELANE), recombinant human

Artikelnummer: CSB-BP007587HU.1

Organism: Homo sapiens (Human). Source: Baculovirus. Expression Region: 30-267aa. Protein Length: Full Length of Mature Protein. Tag Info: C-terminal 10xHis-tagged. Target Protein Sequence: IVGGRRARPH AWPFMVSLQL RGGHFCGATL IAPNFVMSAA HCVANVNVRA VRVVLGAHNL SRREPTRQVF AVQRIFENGY DPVNLLNDIV ILQLNGSATI NANVQVAQLP...
Schlagworte: HLE, ELA2, ELANE, Medullasin, Elastase-2, PMN elastase, EC=3.4.21.37, Neutrophil elastase, Human leukocyte elastase, Bone...
Anwendung: Activity not tested
Exprimiert in: Insect cells
Ursprungsart: human
MW: 31.2 kD
ab 489,00 €
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Neutrophil elastase (ELANE), recombinant human
Neutrophil elastase (ELANE), recombinant human

Artikelnummer: CSB-MP007587HU.1

Organism: Homo sapiens (Human). Source: Mammalian cell. Expression Region: 30-267aa. Protein Length: Full Length of Mature Protein. Tag Info: C-terminal hFc-tagged. Target Protein Sequence: IVGGRRARPH AWPFMVSLQL RGGHFCGATL IAPNFVMSAA HCVANVNVRA VRVVLGAHNL SRREPTRQVF AVQRIFENGY DPVNLLNDIV ILQLNGSATI NANVQVAQLP...
Schlagworte: HLE, ELA2, ELANE, Medullasin, Elastase-2, PMN elastase, EC=3.4.21.37, Neutrophil elastase, Human leukocyte elastase, Bone...
Anwendung: Activity not tested
Exprimiert in: Mammalian cells
Ursprungsart: human
MW: 54.5 kD
ab 371,00 €
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Neutrophil Elastase Activity Assay Kit
Neutrophil Elastase Activity Assay Kit

Artikelnummer: Cay600610-192

Cayman's Neutrophil Elastase Activity Assay kit employs a specific non-fluorescent elastase substrate, (Z-Ala-Ala-Ala-Ala)2Rh110, which is selectively cleaved by elastase to yield the highly fluorescent compound R110. Fluorescence can be analyzed with an excitation wavelength of 485 nm and emission wavelength of 525...
Schlagworte: HLE, ELA2, ELANE, Elastase-2, Medullasin, EC=3.4.21.37, PMN elastase, Neutrophil elastase, Human leukocyte elastase, Bone...
Anwendung: Neutrophile elastase detection
Spezies-Reaktivität: human
556,00 €
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Screen Quest(TM) Fluorimetric Neutrophil Elastase Inhibitor Screening Kit
Screen Quest(TM) Fluorimetric Neutrophil Elastase...

Artikelnummer: ABD-11802

The Screen Quest(TM) Fluorimetric Neutrophil Elastase Inhibitor Screening Kit offers a fast, sensitive, and high-throughput method for screening and characterizing potential inhibitors of NE. This assay measures the NE activity based on hydrolysis of the substrate, producing a fluorescent product with...
Anwendung: NE inhibitor screening, HTS
744,00 €
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N-Methoxysuccinyl-Ala-Ala-Pro-Val-7-amido-4-methylcoumarin [N-Methoxysuccinyl-AAPV-AMC]
N-Methoxysuccinyl-Ala-Ala-Pro-Val-7-amido-4-methylcoumari...

Artikelnummer: ABD-13419

N-Methoxysuccinyl-Ala-Ala-Pro-Val-7-amido-4-methylcoumarin has been used as a fluorogenic substrate in determining the elastase activity from bone marrow lysates and pancreatic lysates. It is also used for detecting the neutrophil elastase in bronchial epithelial cells. The protease activity is measured by...
Anwendung: Fluorogenic elastase substrate
245,00 €
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Anti-ELANE
Anti-ELANE

Artikelnummer: ATA-HPA073774.100

Polyclonal Antibody against Human ELANE, Gene description: elastase, neutrophil expressed, Alternative Gene Names: ELA2, HLE, HNE, NE, PMN-E, Validated applications: IHC, Uniprot ID: P08246, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C. Protein function: Modifies the...
Schlagworte: Anti-HLE, Anti-ELA2, Anti-ELANE, Anti-Medullasin, Anti-Elastase-2, Anti-PMN elastase, EC=3.4.21.37, Anti-Neutrophil...
Anwendung: IHC
Wirt: Rabbit
Spezies-Reaktivität: human
450,00 €
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MeOSuc-AAPV-pNA
MeOSuc-AAPV-pNA

Artikelnummer: Cay17601-10

Proteinase 3 (PR3, myeloblastin) is a polymorphonuclear leukocyte serine proteinase that degrades matrix proteins including fibronectin, laminin, vitronectin, and collagen type IV to generate antimicrobial peptides. Neutrophil elastase is a serine proteinase that is secreted by neutrophils during inflammation to...
Schlagworte: N-(4-methoxy-1,4-dioxobutyl)-L-alanyl-L-alanyl-L-prolyl-N-(4-nitrophenyl)-L-valinamide
Anwendung: Neutrophil elastase & PR3 substrate
CAS 70967-90-7
MW: 590.6 D
ab 90,00 €
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Sivelestat
Sivelestat

Artikelnummer: TGM-T6986-5mg

Description: Sivelestat (ONO5046) is a potent and selective inhibitor of neutrophil elastase with IC50 of 44 nM. Target: Others, SARS-CoV, Serine Protease. Smiles: CC(C)(C)C(=O)Oc1ccc(cc1)S(=O)(=O)Nc1ccccc1C(=O)NCC(O)=O. References: Li G, et al. Int J Mol Med. 2016, 38(3):767-75.
Schlagworte: EI546, ONO5046, LY544349
Anwendung: Targets leukocyte elastase [EC:3.4.21.37] (ELANE)
CAS 127373-66-4
MW: 434.46 D
ab 42,00 €
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Sivelestat sodium tetrahydrate
Sivelestat sodium tetrahydrate

Artikelnummer: TGM-T20762-100mg

Description: Sivelestat sodium tetrahydrate (ONO5046 sodium tetrahydrate) is a competitive inhibitor of human neutrophil elastase, with an IC50 of 44 nM and a Ki of 200 nM. Sivelestat (EI546) sodium tetrahydrate has the potential for the study of acute lung injury/acute respiratory distress syndrome or disseminated...
Schlagworte: Sivelestat Sodium Hydrate, ONO5046, Sivelestat Sodium, ONO 5046, ONO5046 sodium tetrahydrate, ONO-5046 sodium...
Anwendung: Targets leukocyte elastase [EC:3.4.21.37] (ELANE)
CAS 201677-61-4
MW: 528.51 D
ab 42,00 €
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Elasnin
Elasnin

Artikelnummer: TGM-T27251-5mg

Description: Elasnin is a reversible inhibitor of elastase for human granulocyte and pancreatic enzymes with IC50 values of 1.3 and 30 µg/ml, respectively. Target: Others. Smiles: CCCCCC(=O)C(CCCC)c1oc(=O)c(CCCC)c(O)c1CCCC. References: Cook L, Ternai B, Ghosh P. Inhibition of human sputum elastase by substituted...
Anwendung: Leukocyte elastase inhibitor
CAS 68112-21-0
MW: 392.57 D
958,00 €
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Alvelestat
Alvelestat

Artikelnummer: TGM-T3107-100mg

Description: Alvelestat (AZD9668) is an orally bioavailable, selective, and reversible inhibitor of human neutrophil elastase (NE), exhibiting potential anti-inflammatory activity. Target: Others, Serine Protease. Smiles: Cc1c(cc(C(=O)NCc2ccc(cn2)S(C)(=O)=O)c(=O)n1-c1cccc(c1)C(F)(F)F)-c1ccnn1C. References: Stevens...
Schlagworte: AZD9668, Avelestat
Anwendung: Neutrophil elastase inhibitor
CAS 848141-11-7
MW: 545.53 D
ab 31,00 €
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MeOSuc-AAPV-pNA
MeOSuc-AAPV-pNA

Artikelnummer: TGM-T38363-10mg

Description: Proteinase 3 (PR3, myeloblastin) is a polymorphonuclear leukocyte serine proteinase that degrades matrix proteins including fibronectin, laminin, vitronectin, and collagen type IV to generate antimicrobial peptides. Neutrophil elastase is a serine proteinase that is secreted by neutrophils during...
Anwendung: Neutrophil elastase & PR3 substrate
CAS 70967-90-7
MW: 590.63 D
ab 77,00 €
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