Zu "K01322" wurden 50 Artikel gefunden!
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Z-Prolyl-prolinal
Artikelnummer: Cay41535-1
Z-Prolyl-prolinal (ZPP) is an inhibitor of prolyl endopeptidase (Kis = 0.35 and 0.5 nM for the mouse and human enzymes, respectively). ZPP (4 and 40 µM) inhibits the formation of angiotensin (1-7) from angiotensin II in kidney sections isolated from wild-type and Ace2-/- mice. In vivo, ZPP (10 and 50 mg/kg) reduces...
| Schlagworte: | Benzyloxycarbonyl-prolyl-prolinal, ZPP, (2S)-2-[[(2S)-2-formyl-1-pyrrolidinyl]carbonyl]-1-pyrrolidinecarboxylic acid,... |
| Anwendung: | Prolyl endopeptidase inhibitor |
| CAS | 86925-97-5 |
| MW: | 296.4 D |
ab 35,00 €
PREP inhibitor-1
Artikelnummer: TGM-T61622-1mg
Description: PREP inhibitor-1 is a prolyl oligopeptidase (PREP) inhibitor for the study of Alzheimer's disease. Target: Others. Smiles: C(=O)(N1[C@@H](CCC1)C=2NC=CN2)[C@H]3N(C(CCCC4=CC=CC=C4)=O)CCC3. References: Pätsi HT, et al. 2-Imidazole as a Substitute for the Electrophilic Group Gives Highly Potent Prolyl...
| Anwendung: | Prolyl endopeptidase (PREP) inhibitor |
| CAS | 2760543-16-4 |
| MW: | 380.48 D |
ab 194,00 €
Albocycline
Artikelnummer: TGM-T25027-25mg
Description: Albocycline is a Macrolide antibiotic from Streptomyces bruneogriseus nov. sp. MCRL-0129, specifically anti-staphylococcal, including antibiotic-resistant strains. Target: Others. Smiles: O(C)[C@H]\1/C=C/[C@@](C)(O)/C=C/C(=O)O[C@H](C)[C@@H](C)CC/C=C1\C. References: Liang H, Zhou G, Ge Y, D'Ambrosio EA,...
| Schlagworte: | TA-2407, Ingramycin |
| Anwendung: | Antibiotic, prolyl oligopeptidase inhibitor |
| CAS | 25129-91-3 |
| MW: | 308.41 D |
1.520,00 €
Baicalin
Artikelnummer: TGM-T2775-100mg
Description: Baicalin (Baicalein 7-O-beta-D-glucuronide) is a prolyl endopeptidase inhibitor isolated from scutellaria baicalensis, with antioxidant, anti-tumor, anti-HIV properties. Target: NF-kappaB, GABA Receptor, Autophagy, HIV Protease. Smiles:...
| Schlagworte: | Baicalein 7-O-beta-D-glucuronide |
| Anwendung: | Chemotherapeutic, prolyl oligopeptidase inhibitor, neuraminidase inhibitor |
| CAS | 21967-41-9 |
| MW: | 446.36 D |
ab 31,00 €
KYP-2047
Artikelnummer: TGM-T8657-100mg
Description: KYP-2047 is a very potent, selective Prolyl oligopeptidase (POP) inhibitor. Target: Others. Smiles: C(=O)([C@H]1N(C(CCCC2=CC=CC=C2)=O)CCC1)N3[C@H](C#N)CCC3. References: T T Myöhänen 1 , M J Hannula, R Van Elzen,et al.A prolyl oligopeptidase inhibitor, KYP-2047, reduces alpha-synuclein protein levels and...
| Anwendung: | Prolyl endopeptidase inhibitor |
| CAS | 796874-99-2 |
| MW: | 339.43 D |
ab 40,00 €
Prolyl Endopeptidase Protein, Mouse, Recombinant (His)
Artikelnummer: TGM-TMPY-03269-50ug
Description: Prolyl endopeptidase, also known as PREP, belongs to a distinct class of serine peptidases. It is a large cytosolic enzyme which was first described in the cytosol of rabbit brain as an oligopeptidase. Prolyl endopeptidase degrades the nonapeptide bradykinin at the Pro-Phe bond. It is involved in the...
| Schlagworte: | AI047692, AI450383, PEP, D10Wsu136e, Pop, prolyl endopeptidase |
| MW: | 82.9 kD |
599,00 €
Prolyl Endopeptidase Inhibitor 1
Artikelnummer: TGM-T12546-100mg
Description: Prolyl Endopeptidase Inhibitor 1 is a potent inhibitor of prolyl endopeptidase (PEP, PE)(Ki : 15 nM) , has anti-amnesic effect. Target: Others. Smiles: CC(C)(C)OC(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C=O. References: Yoshimoto T, et al. Specific inhibitors for prolyl endopeptidase and their anti-amnesic...
| Schlagworte: | Boc-Pro-prolinal, BPP, (Boc)-Prolyl-prolinal |
| Anwendung: | Prolyl Endopeptidase (PREP) inhibitor |
| CAS | 86925-97-5 |
| MW: | 296.36 D |
ab 217,00 €
Prolyl endopeptidase (PREP), human, recombinant
Artikelnummer: CSB-EP018664HU.1
Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 2-710aa. Protein Length: Full Length of Mature Protein. Tag Info: N-terminal 10xHis-tagged and C-terminal Myc-tagged. Target Protein Sequence: LSLQYPDVYR DETAVQDYHG HKICDPYAWL EDPDSEQTKA FVEAQNKITV PFLEQCPIRG LYKERMTELY DYPKYSCHFK KGKRYFYFYN...
| Schlagworte: | PE, PEP, PREP, EC=3.4.21.26, Prolyl endopeptidase, Post-proline cleaving enzyme, Recombinant Human Prolyl endopeptidase... |
| Anwendung: | Activity not tested |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 88.0 kD |
ab 219,00 €
Prolyl endopeptidase (Prep), mouse, recombinant
Artikelnummer: CSB-EP018664MO.1
Organism: Mus musculus (Mouse). Source: E.coli. Expression Region: 1-710aa. Protein Length: Full Length. Tag Info: C-terminal 6xHis-tagged. Target Protein Sequence: MLSFQYPDVY RDETSVQEYH GHKICDPYSW LEDPDSEQTK AFVEAQNKIT VPFLEQCPIR GLYKERMTEL YDYPKYSCHF KKGKRYFYFY NTGLQNQRVL YVQDSLEGEA RVFLDPNTLS DDGTVALRGY...
| Schlagworte: | PE, Pep, Prep, EC=3.4.21.26, Prolyl endopeptidase, Post-proline cleaving enzyme, Recombinant Mouse Prolyl endopeptidase... |
| Anwendung: | Activity not tested |
| Exprimiert in: | E.coli |
| Ursprungsart: | mouse |
| MW: | 87.7 kD |
ab 247,00 €
Anti-PREP
Artikelnummer: CSB-PA004861.100
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
| Schlagworte: | Anti-PE, Anti-PEP, Anti-PREP, EC=3.4.21.26, Anti-Prolyl endopeptidase, Anti-Post-proline cleaving enzyme, PREP, PEP,... |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 126,00 €
Prolyl Oligopeptidase/Prolyl Endopeptidase, active human...
Artikelnummer: BPS-80105
Active human Prolyl oligopeptidase (POP)/Prolyl endopeptidase (PREP) (GenBank Accession No. NM_002726.) full length with N-terminal His tag, MW = 81.6 kDa, expressed in an E. coli expression system.
| Schlagworte: | PE, PEP, PREP, EC=3.4.21.26, Prolyl endopeptidase, Post-proline cleaving enzyme, |
| Anwendung: | Enzyme kinetics, inhibitor screening |
| MW: | 81.6 kD |
611,00 €
KYP-2047
Artikelnummer: Cay39180-1
KYP-2047 is an inhibitor of prolyl endopeptidase (Ki = 0.02 nM for the porcine enzyme). It inhibits hydrogen peroxide-induced aggregation of alpha-synuclein in SH-SY5Y cells expressing wild-type, alpha-synucleinA30P, or alpha-synucleinA53T in in vitro models of Parkinson's disease when used at a concentration of 1...
| Schlagworte: | (2S)-1-[[(2S)-1-(1-oxo-4-phenylbutyl)-2-pyrrolidinyl]carbonyl]-2-pyrrolidinecarbonitrile |
| Anwendung: | Prolyl endopeptidase inhibitor |
| CAS | 796874-99-2 |
| MW: | 339.4 D |
ab 81,00 €