Zu "K01314" wurden 85 Artikel gefunden!
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Apixaban
Artikelnummer: TGM-T1736-10mg
Description: Apixaban (BMS-562247-01) is an orally active anticoagulant that inhibits coagulation factor Xa, directly preventing the conversion of prothrombin to thrombin and the formation of cross-linked fibrin clots. Target: Factor Xa. Smiles: O=C1C=2N(N=C(C(N)=O)C2CCN1C3=CC=C(C=C3)N4C(=O)CCCC4)C5=CC=C(OC)C=C5....
| Schlagworte: | BMS-562247-01 |
| Anwendung: | Targets coagulation factor X [EC:3.4.21.6] (F10) |
| CAS | 503612-47-3 |
| MW: | 459.5 D |
ab 35,00 €
Fidexaban
Artikelnummer: TGM-T27318-1mg
Description: Fidexaban (CI1031) is a novel, potent, selective and orally active factor Xa inhibitor that has demonstrated antithrombotic activity in a variety of assays. Target: Factor Xa. Smiles: O(C1=C(F)C(N(CC(O)=O)C)=C(F)C(OC2=CC(=CC=C2)C=3N(C)CCN3)=N1)C4=CC(C(=N)N)=CC=C4O. References: Remko MR, et al....
| Schlagworte: | PD-200022, BX-807834, CI-1031, ZK-807834, BX807834, CI1031 |
| Anwendung: | Targets coagulation factor X [EC:3.4.21.6] (F10) |
| CAS | 183305-24-0 |
| MW: | 526.49 D |
ab 143,00 €
Bz-IEGR-pNA (acetate)
Artikelnummer: TGM-T35926-10mg
Description: Bz-IEGR-pNA is a colorimetric substrate for Factor Xa.1 Factor Xa preferentially binds to and cleaves the Ile-Glu-Gly-Arg (IEGR) peptide sequence to release p-nitroanilide (pNA), which can be quantified by colorimetric detection at 405 nm as a measure of Factor Xa activity. Target: Others. Smiles:...
| Anwendung: | Photometric Factor Xa substrate |
| CAS | 1325307-57-0 |
| MW: | 757.802 D |
ab 79,00 €
Suc-Ile-Glu(gamma-pip)-Gly-Arg-pNA hydrochloride
Artikelnummer: TGM-T38795-10mg
Description: Suc-Ile-Glu(gamma-pip)-Gly-Arg-pNA hydrochloride is a chromogenic substrate specifically designed for factor Xa. Smiles: Cl.CC[C@H](C)[C@H](NC(=O)CCC(O)=O)C(=O)N[C@@H](CCC(=O)N1CCCCC1)C(=O)NCC(=O)N[C@@H](CCCNC(N)=N)C(=O)Nc1ccc(cc1)[N+]([O-])=O. References: Thierry Schmitz, et al. Oral heparin delivery:...
| Anwendung: | Photometric Factor Xa substrate |
| CAS | 1379822-04-4 |
| MW: | 797.31 D |
ab 124,00 €
Z-D-Arg-Gly-Arg-pNA . 2 HCl
Artikelnummer: TGM-T37054-10mg
Description: Z-RGR-pNA is a chromogenic substrate for the determination of factor Xa. Target: Others. Smiles: Cl.Cl.NC(=N)NCCC[C@@H](NC(=O)OCc1ccccc1)C(=O)NCC(=O)N[C@@H](CCCNC(N)=N)C(=O)Nc1ccc(cc1)N(=O)=O
| Anwendung: | Photometric Factor Xa substrate |
| CAS | 113711-77-6 |
| MW: | 714.61 D |
ab 124,00 €
TPU-0037A
Artikelnummer: TGM-T37731-5mg
Description: TPU-0037A is an antibiotic and a congener of lydicamycin. It inhibits the growth of Gram-positive bacteria, including methicillin-resistant S. aureus (MRSA), B. subtilis, and M. luteus (MICs = 1.56-12.5 µg/ml), but not Gram-negative E. coli, P. mirabilis, P. vulgaris, or P. aeruginosa strains (MICs =...
| Anwendung: | Factor Xa inhibitor, GC-MS, LC-MS, internal standard |
| CAS | 485815-59-6 |
| MW: | 841.1 D |
3.458,00 €
Betrixaban
Artikelnummer: TGM-T4341-100mg
Description: Betrixaban (PRT054021) is a non-vitamin K oral anticoagulant whose action is driven by the competitive and reversible inhibition of the factor Xa [1]. It was selected among all lead compounds due to its low hERG channel affinity while sustaining its factor Xa inhibition capacity [3]. Betrixaban, now...
| Schlagworte: | PRT054021 |
| Anwendung: | Targets coagulation factor X [EC:3.4.21.6] (F10) |
| CAS | 330942-05-7 |
| MW: | 451.91 D |
ab 41,00 €
Emicizumab
Artikelnummer: TGM-T77457-100mg
Description: Emicizumab(ACE 910) is a humanized monoclonal antibody that bridges activated factor IX and activated factor X to mimic the function of activated factor VIII. Emicizumab is used for the prevention and treatment of hemophilia A. It has been shown to be effective in the treatment of hemophilia A. It has...
| Schlagworte: | ACE 910, RO 5534262 |
| Anwendung: | Targets coagulation factor IX (Christmas factor) [EC:3.4.21.22] (F9) |
| CAS | 1610943-06-0 |
ab 1.982,00 €
Coagulation factor X/F10 Protein, Mouse, Recombinant (His)
Artikelnummer: TGM-TMPJ-00707-10ug
Description: Mouse coagulation factor X / F10 a member of the peptidase S1 family. The mature F10 is composed mostly of two EGF-like domains, one Gla gamma-carboxy-glutamate domain and one peptidase S1 domain. Factor Xa is a vitamin K-dependent plasma protease that converts prothrombin to thrombin in the presence of...
| Schlagworte: | F10, Coagulation factor X, Stuart factor |
| MW: | 28 kD |
ab 184,00 €
Coagulation factor X/F10 Protein, Human, Recombinant (His)
Artikelnummer: TGM-TMPY-01101-100ug
Description: Coagulation factor X, also known as FX, F10, Eponym Stuart-Prower factor, and thrombokinase, is an enzyme of the coagulation cascade. It is one of the vitamin K-dependent serine proteases, and plays a crucial role in the coagulation cascade and blood clotting, as the first enzyme in the common pathway...
| Schlagworte: | coagulation factor 10, coagulation factor X, FXA, FX |
| MW: | 52.8 kD |
ab 386,00 €
Edoxaban-d6
Artikelnummer: TGM-TMIJ-0132-1mg
Description: Edoxaban-d6 is a deuterated compound of Edoxaban. Edoxaban has a CAS number of 480449-70-5. Edoxaban(DU-176) is an oral factor Xa (FXa) inhibitor in clinical development for stroke prevention. Smiles:...
| Anwendung: | Factor Xa inhibitor, GC-MS, LC-MS, internal standard |
| CAS | 1304701-57-2 |
| MW: | 554.09 D |
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Coagulation Factor X Protein, Human, Recombinant (hFc)
Artikelnummer: TGM-TMPJ-00301-10ug
Description: F10, also known as Coagulation factor X, belongs to the peptidase S1 family that is synthesized as a 488 amino acid (aa) with a signal peptide and a pro region (residues 1-40). Both the intrinsic and extrinsic pathways activate Factor X to Xa, which consists of light (residues 41-179) and heavy...
| Schlagworte: | Coagulation factor X, Stuart-Prower factor, Stuart factor |
| MW: | 25 kD |
ab 184,00 €