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PPACK (trifluoroacetate salt)
PPACK (trifluoroacetate salt)

Artikelnummer: Cay15160-10

PPACK is a synthetic peptide derivative that irreversibly and specifically inhibits thrombin-mediated platelet activation by binding with high affinity to the active site of thrombin (Ki = 0.24 nM). It has been used as an anticoagulant (100 µM) and to study thrombin-mediated fibrin deposition, angiogenesis, and...
Schlagworte: D-Phenylalanyl-prolyl-arginyl Chloromethyl Ketone, Pebac,...
Anwendung: Thrombin inhibitor
MW: 451 D
ab 50,00 €
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(BOC-VPR)2R110
(BOC-VPR)2R110

Artikelnummer: ABD-13462

(BOC-VPR)2R110 is a sentive fluorogenic substrate for alpha-thrombin. The non-fluorescent substrate generates a bright green fluorescent R110 product that has Ex/Em = 495/520 nm, and can be easily detected with the FITC filter set. This substrate has also been used for the rapid detection of MRSA...
Anwendung: Fluorogenic alpha-thrombin substrate
139,00 €
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PPACK (hydrochloride)
PPACK (hydrochloride)

Artikelnummer: Cay37489-5

PPACK is a synthetic peptide derivative that irreversibly and specifically inhibits thrombin-mediated platelet activation by binding with high affinity to the active site of thrombin (Ki = 0.24 nM). It has been used as an anticoagulant (100 µM) and to study thrombin-mediated fibrin deposition, angiogenesis, and...
Schlagworte: D-Phenylalanyl-prolyl-arginyl Chloromethyl Ketone, D-Phe-Pro-Arg-CH2Cl, Pebac,...
Anwendung: Thrombin-mediated platelet activation inhibitor
CAS 82188-90-7
MW: 523.9 D
ab 48,00 €
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Mouse F2 (Coagulation Factor II) ELISA Kit
Mouse F2 (Coagulation Factor II) ELISA Kit

Artikelnummer: ELK-ELK1518.48

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Mouse F2. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Mouse F2. Next,...
Schlagworte: F2, Cf2, EC=3.4.21.5
Anwendung: ELISA
Spezies-Reaktivität: mouse
ab 365,00 €
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Cattle F2 (Coagulation Factor II) ELISA Kit
Cattle F2 (Coagulation Factor II) ELISA Kit

Artikelnummer: ELK-ELK8258.48

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Cattle F2. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Cattle F2. Next,...
Schlagworte: F2, EC=3.4.21.5
Anwendung: ELISA
Spezies-Reaktivität: cattle
ab 470,00 €
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Human F2 (Coagulation Factor II) ELISA Kit
Human F2 (Coagulation Factor II) ELISA Kit

Artikelnummer: ELK-ELK1634.48

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human F2. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human F2. Next,...
Schlagworte: F2, EC=3.4.21.5
Anwendung: ELISA
Spezies-Reaktivität: human
ab 365,00 €
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Thrombin Inhibitor Screening Assay Kit
Thrombin Inhibitor Screening Assay Kit

Artikelnummer: BPS-78867-1

The Thrombin Inhibitor Screening Assay is a colorimetric assay designed to measure the activity of human alpha thrombin for screening and profiling applications. The assay kit comes in a convenient 96-well or 384-well format and contains enough purified human alpha thrombin, a chromogenic substrate, and PR-02 buffer...
Schlagworte: F2, EC=3.4.21.5,
Anwendung: Inhibitor screening, HTS
Spezies-Reaktivität: human
ab 1.065,00 €
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Dabigatran
Dabigatran

Artikelnummer: Cay17133-1

Dabigatran is an inhibitor of thrombin (Ki = 0.0045 µM) and an active metabolite of the thrombin inhibitor prodrug dabigatran etexilate (Cay-17131). It also inhibits trypsin (Ki = 0.0503 µM) but is selective for thrombin and trypsin over plasmin, Factor Xa, activated protein C, and tissue plasminogen activator (tPA,...
Schlagworte: BIBR 953,...
Anwendung: Thrombin inhibitor
CAS 211914-51-1
MW: 471.5 D
ab 43,00 €
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Melagatran
Melagatran

Artikelnummer: Cay9002300-2

Melagatran is an inhibitor of thrombin (Ki = 0.002 µM) and an active metabolite of the prodrug ximelagatran (Cay-16862). It is selective for thrombin over a variety of serine proteases (Kis = 0.6-10.2 µM) but also inhibits trypsin (Ki = 0.004 µM). Melagatran inhibits thrombin-induced aggregation of isolated washed...
Schlagworte: N-[(1R)-2-[(2S)-2-[[[[4-(aminoiminomethyl)phenyl]methyl]amino]carbonyl]-1-azetidinyl]-1-cyclohexyl-2-oxoethyl]-glycine
Anwendung: Thrombin inhibitor, active ximelagatran metabolite
CAS 159776-70-2
MW: 429.5 D
715,00 €
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p-APMSF (hydrochloride)
p-APMSF (hydrochloride)

Artikelnummer: Cay14971-1

p-APMSF is an irreversible inhibitor of serine proteases with Ki values of 1.02, 1.18, 1.5, and 1.54 µM for bovine trypsin, human thrombin, bovine plasmin, and bovine Factor Xa, respectively. It is selective for these proteases over bovine chymotrypsin and acetylcholinesterase.Formal Name:...
Schlagworte: (p-Amidinophenyl)methanesulfonyl Fluoride, para-APMSF, 4-(aminoiminomethyl)-benzenemethanesulfonyl fluoride,...
Anwendung: Irreversible serine protease rreversible inhibitor of serine protease
CAS 74938-88-8
MW: 252.7 D
ab 44,00 €
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Bivalirudin
Bivalirudin

Artikelnummer: Cay23035-5

Bivalirudin is an inhibitor of alpha- and zeta-thrombin (Kis = 2.56 and 1.84 nM, respectively), enzymes that exhibit high fibrinogen-clotting activities. It is selective for alpha- and zeta-thrombin, lacking activity at trypsin and gamma-thrombin, which lacks clotting activity, at a >1,000-fold excess of...
Schlagworte: D-phenylalanyl-L-prolyl-L-arginyl-L-prolylglycylglycylglycylglycyl-L-asparaginylglycyl-L-alpha-aspartyl-L-phenylalanyl-L-a...
Anwendung: alpha- & zeta-thrombin inhibitor
CAS 128270-60-0
MW: 2180.3 D
ab 84,00 €
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Sucrose octasulfate (potassium salt)
Sucrose octasulfate (potassium salt)

Artikelnummer: Cay16382-1

Sucrose octasulfate (SOS), a component of the gastrointestinal protectant sucralfate, is an alkaline aluminum-sucrose complex that inhibits peptic hydrolysis and raises gastric pH, protecting esophageal epithelium against acid injury. It can bind to exosite II of thrombin (KD = ~1.4 µM) and inhibit its catalytic...
Schlagworte: SOS, Sucrosofate potassium, 2,3,4,6-tetrakis(hydrogen sulfate),1,3,4,6-tetra-O-sulfo-beta-D-fructofuranosyl...
Anwendung: Thrombin inhibitor
CAS 73264-44-5
MW: 1287.5 D
ab 117,00 €
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