Zu "K01313" wurden 107 Artikel gefunden!
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Melagatran
Artikelnummer: Cay9002300-2
Melagatran is an inhibitor of thrombin (Ki = 0. µM) and an active metabolite of the prodrug ximelagatran (Cay-16862). It is selective for thrombin over a variety of serine proteases (Kis = 0.6-10. µM) but also inhibits trypsin (Ki = 0. µM). Melagatran inhibits thrombin-induced aggregation of isolated washed human...
| Schlagworte: | N-[(1R)-2-[(2S)-2-[[[[4-(aminoiminomethyl)phenyl]methyl]amino]carbonyl]-1-azetidinyl]-1-cyclohexyl-2-oxoethyl]-glycine |
| Anwendung: | Thrombin inhibitor, ximelagatran metabolite |
| CAS | 159776-70-2 |
| MW: | 429.5 D |
732,00 €
PPACK (trifluoroacetate salt)
Artikelnummer: Cay15160-10
PPACK is a synthetic peptide derivative that irreversibly and specifically inhibits thrombin-mediated platelet activation by binding with high affinity to the active site of thrombin (Ki = 0.24 nM). It has been used as an anticoagulant (100 µM) and to study thrombin-mediated fibrin deposition, angiogenesis, and...
| Schlagworte: | D-Phenylalanyl-prolyl-arginyl Chloromethyl Ketone, Pebac,... |
| Anwendung: | Thrombin inhibitor |
| MW: | 451 D |
ab 52,00 €
(BOC-VPR)2R110
Artikelnummer: ABD-13462
(BOC-VPR)2R110 is a sentive fluorogenic substrate for alpha-thrombin. The non-fluorescent substrate generates a bright green fluorescent R110 product that has Ex/Em = 495/520 nm, and can be easily detected with the FITC filter set. This substrate has also been used for the rapid detection of MRSA...
| Anwendung: | Fluorogenic alpha-thrombin substrate |
141,00 €
Dabigatran Etexilate Mesylate
Artikelnummer: TGM-T5133-100mg
Description: Dabigatran Etexilate Mesylate (BIBR 1048MS) is the orally active prodrug of dabigatran. Dabigatran is a reversible and selective, direct thrombin inhibitor (DTI, Ki: 4.5 nM). Target: Thrombin. Smiles: CS(O)(=O)=O.CCCCCCOC(=O)NC(=N)c1ccc(NCc2nc3cc(ccc3n2C)C(=O)N(CCC(=O)OCC)c2ccccn2)cc1. References:...
| Schlagworte: | BIBR 1048MS, Dabigatran etexilate methanesulfonate |
| Anwendung: | Targets coagulation factor II (thrombin) [EC:3.4.21.5] (F2) |
| CAS | 872728-81-9 |
| MW: | 723.84 D |
ab 37,00 €
Bivalirudin
Artikelnummer: TGM-T5519-100mg
Description: Bivalirudin (BG-8967) is a reversible inhibitor of alpha- and zeta-thrombin (Kis = 2.56 and 1.84 nM, respectively), enzymes that exhibit high fibrinogen-clotting activities. Target: Thrombin. Smiles:...
| Schlagworte: | BG-8967, Hirulog-1 |
| Anwendung: | Targets coagulation factor II (thrombin) [EC:3.4.21.5] (F2) |
| CAS | 128270-60-0 |
| MW: | 2180.29 D |
ab 38,00 €
Thrombin inhibitor 6
Artikelnummer: TGM-T72448-100mg
Description: Thrombin Inhibitor 6, with an IC 50 of 1 nM, acts as a potent anticoagulant by inhibiting thrombin. Target: Others. Smiles: O=C1C(C2=NN(C(C(C)(C)C)=O)C(NCC=3SC(Cl)=CC3)=C2)=CC=CN1
| Anwendung: | Thrombin inhibitor |
| CAS | 1628224-94-1 |
| MW: | 390.89 D |
ab 1.520,00 €
Dabigatran-d3
Artikelnummer: TGM-TMIH-0174-1mg
Description: Dabigatran-d3 is a deuterated compound of Dabigatran. Smiles: [2H]C([2H])([2H])N1C(CNC2=CC=C(C=C2)C(N)=N)=NC2=CC(=CC=C12)C(=O)N(CCC(O)=O)C1=CC=CC=N1
| Anwendung: | GC-MS, LC-MS internal standard, quantification, thrombin inhibitor |
| CAS | 1246817-44-6 |
| MW: | 474.53 D |
ab 311,00 €
Thrombin inhibitor 5
Artikelnummer: TGM-T9845-100mg
Description: Thrombin inhibitor 5 (compound 385) is a thrombin inhibitor with IC50 values ranging from 0.1 µM to 1 µM, suitable for venous thromboembolism research[1]. Target: Others. Smiles: COC(=O)c1n[nH]c(NC(=O)c2ccc(F)cc2)n1
| Anwendung: | Thrombin inhibitor |
| CAS | 328108-09-4 |
| MW: | 264.21 D |
ab 33,00 €
Prothrombin Protein, Human, Recombinant (His)
Artikelnummer: TGM-TMPH-01974-100ug
Description: Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing. Prothrombin Protein, Human, Recombinant (His) is expressed in yeast...
| Schlagworte: | Coagulation factor II, Prothrombin, F2 |
| MW: | 67.3 kD |
ab 339,00 €
Prothrombin Protein, Human, Recombinant (His & SUMO)
Artikelnummer: TGM-TMPH-01975-100ug
Description: Prothrombin Protein, Human, Recombinant (His & SUMO) is expressed in E. coli.
| Schlagworte: | F2, Prothrombin, Coagulation factor II |
| MW: | 81.3 kD |
ab 198,00 €
Coagulation Factor II Protein, Rat, Recombinant (His)
Artikelnummer: TGM-TMPY-04996-50ug
Description: Coagulation Factor II Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 69.5 kDa and the accession number is A6HND0.
| Schlagworte: | coagulation factor II (thrombin) |
| MW: | 69.5 kD |
699,00 €
Coagulation Factor II Protein, Mouse, Recombinant (His)
Artikelnummer: TGM-TMPY-01791-20ug
Description: Coagulation Factor II Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 69.3 kDa and the accession number is P19221.
| Schlagworte: | Cf-2, coagulation factor II (thrombin), Cf2, FII |
| MW: | 69.3 kD |
355,00 €