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Zu "K01278" wurden 218 Artikel gefunden!
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Artikelnummer: Cay700210-96
DPP (IV) inhibitors have emerged as a new class of oral antidiabetic agents. These inhibitors promote glucose homeostasis by inhibiting degradation of glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) by DPP (IV). GLP-1 extends the action of insulin while suppressing the release...
Schlagworte: | Dipeptidyl peptidase IV |
Anwendung: | DPP (IV) inhibitor screening |
Spezies-Reaktivität: | human |
467,00 €
Artikelnummer: E-BC-D007.96
Detection principle: The detection principle of this kit is that DPP4 can decompose the substrate and release fluorescent substance AMC. The addition of DPP4 inhibitor can inhibit the enzyme activity, and the inhibitory ability of the inhibitor can be determined by the fluorescence value. Performance...
Schlagworte: | ADCP2, Dipeptidyl Peptidase IV (DPP4) Inhibitor Screening Assay Kit |
515,00 €
Artikelnummer: ELK-ELK1595.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human DPP4. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human DPP4. Next,...
Schlagworte: | ADCP2 |
Anwendung: | ELISA |
Spezies-Reaktivität: | human |
ab 365,00 €
Artikelnummer: ELK-ELK1596.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Rat DPP4. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Rat DPP4. Next,...
Schlagworte: | Cd26, Dpp4 |
Anwendung: | ELISA |
Spezies-Reaktivität: | rat |
ab 365,00 €
Artikelnummer: ELK-ELK1597.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Mouse DPP4. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Mouse DPP4. Next,...
Schlagworte: | Cd26, Dpp4 |
Anwendung: | ELISA |
Spezies-Reaktivität: | mouse |
ab 365,00 €
Artikelnummer: G-HDBS0134.100
Protein function: Cell surface glycoprotein receptor involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T- cell activation. Acts as a positive regulator of T-cell coactivation, by binding at least ADA, CAV1, IGF2R, and PTPRC. Its binding to CAV1 and CARD11 induces T-cell proliferation...
Schlagworte: | Anti-Cd26, Anti-Dpp4 |
Anwendung: | FC |
Wirt: | Mouse |
Spezies-Reaktivität: | human |
399,00 €
-15 %
Rabattaktion
Artikelnummer: A700-288
Protein function: Cell surface glycoprotein receptor involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T- cell activation (PubMed:10951221, PubMed:10900005, PubMed:11772392, PubMed:17287217). Acts as a positive regulator of T-cell coactivation, by binding at least ADA, CAV1, IGF2R,...
Schlagworte: | Anti-ADCP2 |
Anwendung: | IHC, ICC, FC |
Wirt: | Rabbit |
Spezies-Reaktivität: | human |
172,00 €
ab 146,20 €
Artikelnummer: E-UNEL-H0038.15
Colormetric. Detection Range: 0.78-50 ng/mL. Protein function: Cell surface glycoprotein receptor involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T- cell activation (PubMed:10951221, PubMed:10900005, PubMed:11772392, PubMed:17287217). Acts as a positive regulator of T-cell...
Schlagworte: | ADCP2 |
Anwendung: | ELISA |
Spezies-Reaktivität: | human |
ab 396,00 €
Artikelnummer: Cay13252-50
(-)-Sitagliptin is a potent inhibitor of dipeptidyl peptidase 4 (DPP-4, IC50 = 18 nM). It is selective for DPP-4 over DPP-8 (IC50 = 48 µM) as well as several other peptidases, including DPP-9, DPP-2, and amino peptidase P. (-)-Sitagliptin improves glucose tolerance in insulin-resistant Zucker fatty and high-fat diet...
Schlagworte: | (R)-Sitagliptin, INN, MK-431, ONO-5435,... |
Anwendung: | DPP4 inhibitor |
CAS | 654671-78-0 |
MW: | 505.3 D |
ab 50,00 €
Artikelnummer: BPS-80040
Active human DPP4 (GenBank Accession No. NM_001935), (amino acids 29-end) with C-terminal His tag, MW=89.1 kDa, expressed in a Baculovirus infected Sf9 cell expression system.
Schlagworte: | ADCP2, |
Anwendung: | Enzyme kinetics, inhibitor screening |
MW: | 89.1 kD |
708,00 €
Artikelnummer: AG-CR1-3618-M050
White to off-white solid. Soluble in DMSO, ethanol or methanol. Slightly soluble in water (~1mg/ml). Antidiabetic agent, Highly potent and selective competitive inhibitor of dipeptidyl-peptidase 4 (DPP4, DPP IV, CD26), an enzyme that degrades, glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic...
Schlagworte: | 8-(3-(R)-Aminopiperidin-1-yl)-7-but-2-ynyl-3-methyl-1-(4-methyl-quinazolin-2-ylmethyl)-3,7-dihydropurine-2,6-dione, BI-1356 |
Anwendung: | Antidiabetic agent, DPP4 inhibitor |
CAS | 668270-12-0 |
MW: | 472,5 D |
ab 50,00 €
Artikelnummer: Cay14705-10
Vildagliptin is an inhibitor of dipeptidyl peptidase 4 (DPP-4, Ki = 0.003 µM). It is selective for DPP-4 over DPP-2, DPP-8, and DPP-9 (Kis = >500, 0.81, and 0.095 µM, respectively). Vildagliptin (3 mg/kg) decreases plasma glucose levels and increases plasma insulin levels during an oral glucose challenge in Zucker...
Schlagworte: | 1-[2-[(3-hydroxytricyclo[3.3.1.13,7]dec-1-yl)amino]acetyl]-2S-pyrrolidinecarbonitrile |
Anwendung: | DPP4 / DPP8 / DPP9 inhibitor |
CAS | 274901-16-5 |
MW: | 303.4 D |
ab 39,00 €